JP2006500372A - 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 - Google Patents

選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 Download PDF

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JP2006500372A
JP2006500372A JP2004530197A JP2004530197A JP2006500372A JP 2006500372 A JP2006500372 A JP 2006500372A JP 2004530197 A JP2004530197 A JP 2004530197A JP 2004530197 A JP2004530197 A JP 2004530197A JP 2006500372 A JP2006500372 A JP 2006500372A
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JP2006500372A5 (https=
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ウェインガーテン，ゴードン
ブラヴィ，ジアンパオロ
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Glaxo Group Ltd
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Glaxo Group Ltd
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Priority claimed from GB0219304A external-priority patent/GB0219304D0/en
Priority claimed from GB0219305A external-priority patent/GB0219305D0/en
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
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  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
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JP2004530197A 2002-08-19 2003-08-15 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 Pending JP2006500372A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0219304A GB0219304D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
GB0219305A GB0219305D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
PCT/EP2003/009153 WO2004018452A1 (en) 2002-08-19 2003-08-15 Pyrimidine derivatives as selective cox-2 inhibitors

Publications (2)

Publication Number Publication Date
JP2006500372A true JP2006500372A (ja) 2006-01-05
JP2006500372A5 JP2006500372A5 (https=) 2006-09-07

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JP2004530197A Pending JP2006500372A (ja) 2002-08-19 2003-08-15 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体

Country Status (8)

Country Link
US (1) US7235560B2 (https=)
EP (1) EP1546128B1 (https=)
JP (1) JP2006500372A (https=)
AT (1) ATE325115T1 (https=)
AU (1) AU2003258630A1 (https=)
DE (1) DE60305053T2 (https=)
ES (1) ES2263058T3 (https=)
WO (1) WO2004018452A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE325115T1 (de) 2002-08-19 2006-06-15 Glaxo Group Ltd Pyrimidinderivate als selektive cox-2-inhibitoren
GB0221443D0 (en) 2002-09-16 2002-10-23 Glaxo Group Ltd Pyridine derivates
LT2801354T (lt) 2004-10-08 2017-06-26 Forward Pharma A/S Kontroliuojamo atpalaidavimo farmacinės kompozicijos, apimančios fumaro rūgšties esterį
US7759350B2 (en) * 2005-09-15 2010-07-20 Orchid Research Laboratories Ltd. Pyrimidine carboxamides
WO2007042035A2 (en) * 2005-10-07 2007-04-19 Aditech Pharma Ab Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders
WO2010079222A1 (en) 2009-01-09 2010-07-15 Forward Pharma A/S Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
EP2547662A4 (en) * 2010-03-17 2013-10-02 Glaxo Group Ltd PYRIMIDINE DERIVATIVES FOR USE AS AGONISTS OF SPHINGOSIN 1-PHOSPHATE 1 (S1P1) RECEPTORS
AU2017275657B2 (en) 2016-06-02 2021-08-19 Novartis Ag Potassium channel modulators
PL3571193T3 (pl) 2017-01-23 2022-04-25 Cadent Therapeutics, Inc. Modulatory kanału potasowego
EP3870291A1 (en) 2018-10-22 2021-09-01 Cadent Therapeutics, Inc. Crystalline forms of potassium channel modulators
EP4027993A4 (en) * 2019-09-13 2023-09-20 The Broad Institute Inc. Cyclooxygenase-2 inhibitors and uses thereof

Citations (6)

* Cited by examiner, † Cited by third party
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