JP2005517407A5 - - Google Patents
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- Publication number
- JP2005517407A5 JP2005517407A5 JP2003568071A JP2003568071A JP2005517407A5 JP 2005517407 A5 JP2005517407 A5 JP 2005517407A5 JP 2003568071 A JP2003568071 A JP 2003568071A JP 2003568071 A JP2003568071 A JP 2003568071A JP 2005517407 A5 JP2005517407 A5 JP 2005517407A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- vector
- host cell
- signal peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/076,802 US7094579B2 (en) | 2002-02-13 | 2002-02-13 | Eukaryotic signal sequences for prokaryotic expression |
| PCT/US2003/004791 WO2003068956A1 (en) | 2002-02-13 | 2003-02-13 | Eukaryotic signal sequences for polypeptide expression and polypeptide display libraries |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009065285A Division JP5190963B2 (ja) | 2002-02-13 | 2009-03-17 | ポリペプチドを発現させるための真核生物シグナル配列およびポリペプチド提示ライブラリー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005517407A JP2005517407A (ja) | 2005-06-16 |
| JP2005517407A5 true JP2005517407A5 (https=) | 2006-03-30 |
| JP4303596B2 JP4303596B2 (ja) | 2009-07-29 |
Family
ID=27732544
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003568071A Expired - Lifetime JP4303596B2 (ja) | 2002-02-13 | 2003-02-13 | ポリペプチドを発現させるための真核生物シグナル配列およびポリペプチド提示ライブラリー |
| JP2009065285A Expired - Fee Related JP5190963B2 (ja) | 2002-02-13 | 2009-03-17 | ポリペプチドを発現させるための真核生物シグナル配列およびポリペプチド提示ライブラリー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009065285A Expired - Fee Related JP5190963B2 (ja) | 2002-02-13 | 2009-03-17 | ポリペプチドを発現させるための真核生物シグナル配列およびポリペプチド提示ライブラリー |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US7094579B2 (https=) |
| EP (2) | EP1481059B1 (https=) |
| JP (2) | JP4303596B2 (https=) |
| AT (2) | ATE406439T1 (https=) |
| AU (1) | AU2003225578B2 (https=) |
| CA (1) | CA2475929C (https=) |
| DE (1) | DE60323210D1 (https=) |
| DK (2) | DK1481059T3 (https=) |
| WO (1) | WO2003068956A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7097840B2 (en) | 2000-03-16 | 2006-08-29 | Genentech, Inc. | Methods of treatment using anti-ErbB antibody-maytansinoid conjugates |
| US7094579B2 (en) * | 2002-02-13 | 2006-08-22 | Xoma Technology Ltd. | Eukaryotic signal sequences for prokaryotic expression |
| US8088387B2 (en) | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
| US8293503B2 (en) | 2003-10-03 | 2012-10-23 | Promega Corporation | Vectors for directional cloning |
| CA2541177A1 (en) * | 2003-10-03 | 2005-09-22 | Promega Corporation | Vectors for directional cloning |
| ATE479760T1 (de) * | 2004-03-24 | 2010-09-15 | Domantis Ltd | Universelles signalpeptid gas1 |
| JP5080269B2 (ja) | 2004-12-07 | 2012-11-21 | ロンザ アーゲー | メリビオースオペロン発現系 |
| CA2589937C (en) * | 2004-12-07 | 2014-04-22 | Lonza Ag | Rhamnose promoter expression system |
| EP2059590B1 (en) * | 2006-07-14 | 2014-12-31 | Novozymes, Inc. | Methods for producing secreted polypeptides having biological activity |
| GB0810154D0 (en) | 2008-06-04 | 2008-07-09 | Avecia Biolog Ltd | Expression vector |
| EP2344686B1 (en) | 2008-10-03 | 2014-03-05 | XOMA Technology Ltd. | Novel triple tag sequences and methods of use thereof |
| JP5745432B2 (ja) * | 2009-02-25 | 2015-07-08 | ネクステラ アーエス | シグナル配列非依存性pIXファージディスプレイ |
| WO2010117420A2 (en) | 2009-03-30 | 2010-10-14 | Pacific Biosciences Of California, Inc. | Fret-labeled compounds and uses therefor |
| JP2014504503A (ja) | 2010-12-28 | 2014-02-24 | ゾーマ テクノロジー リミテッド | Pdzドメインを用いた細胞表面提示 |
| AU2012212047A1 (en) | 2011-02-03 | 2013-08-22 | Xoma Technology Ltd. | Methods and materials for enhancing functional protein expression in bacteria |
| ES3011307T3 (en) | 2012-02-23 | 2025-04-07 | Juno Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| US9803191B2 (en) | 2012-07-05 | 2017-10-31 | Genentech, Inc. | Expression and secretion system |
| EP2877589B1 (en) | 2012-07-26 | 2024-03-06 | Momenta Pharmaceuticals, Inc. | Glycoproteins with anti-inflammatory properties |
| MX2018004875A (es) | 2015-10-22 | 2018-08-01 | Juno Therapeutics Gmbh | Metodos para cultivar celulas y kits y aparatos para ello. |
| EP3365453A2 (en) | 2015-10-22 | 2018-08-29 | Juno Therapeutics GmbH | Methods, kits, agents and apparatuses for transduction |
| US10954500B2 (en) | 2015-10-23 | 2021-03-23 | Fred Hutchinson Cancer Research Center | Methods to create chemically-induced dimerizing protein systems for regulation of cellular events |
| CN105734061B (zh) * | 2016-03-25 | 2019-07-23 | 中国农业科学院生物技术研究所 | 从毕赤酵母中分离的鼠李糖诱导型启动子及其应用 |
| JP7339160B2 (ja) | 2017-04-27 | 2023-09-05 | ジュノ セラピューティクス ゲーエムベーハー | オリゴマー粒子試薬およびその使用方法 |
| EP3444269A1 (en) | 2017-08-17 | 2019-02-20 | National Research Council of Canada | Systems and methods for the production of diphtheria toxin polypeptides |
| IL275239B2 (en) | 2017-12-11 | 2026-03-01 | Abalone Bio Inc | Yeast presentation of proteins in the subplasmic space |
| SG11202104355SA (en) | 2018-10-31 | 2021-05-28 | Juno Therapeutics Gmbh | Methods for selection and stimulation of cells and apparatus for same |
| US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
| IT201900006656A1 (it) | 2019-05-08 | 2020-11-08 | Salvagnini Italia Spa | Macchina piegatrice per lamiere metalliche |
| MX2022010467A (es) * | 2020-02-25 | 2022-12-15 | Momenta Pharmaceuticals Inc | Enzimas para la sialilación de glicanos. |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
| CN116284288A (zh) * | 2023-02-01 | 2023-06-23 | 深圳大学 | 莱茵衣藻分泌导肽和转基因莱茵衣藻及其构建方法与应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| ATE114723T1 (de) | 1987-03-02 | 1994-12-15 | Enzon Lab Inc | Organismus als träger für ''single chain antibody domain (scad)''. |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9011861D0 (en) | 1990-05-26 | 1990-07-18 | Beecham Group Plc | Novel compounds |
| US5723286A (en) | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| DE4022940A1 (de) | 1990-07-19 | 1992-01-23 | Bosch Gmbh Robert | Einrichtung zur temperatursteuerung eines messwiderstands |
| US5401629A (en) | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| CA2095633C (en) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Enrichment method for variant proteins with altered binding properties |
| ATE414768T1 (de) | 1991-04-10 | 2008-12-15 | Scripps Research Inst | Bibliotheken heterodimerer rezeptoren mittels phagemiden |
| DE4122598C1 (https=) * | 1991-07-08 | 1992-07-30 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg, De | |
| EP0605522B1 (en) | 1991-09-23 | 1999-06-23 | Medical Research Council | Methods for the production of humanized antibodies |
| US5470997A (en) | 1992-04-06 | 1995-11-28 | Biosite Diagnostics Incorporated | Amphetamine derivatives and protein and polypeptide amphetamine derivative conjugates and labels |
| US6555310B1 (en) * | 1997-04-04 | 2003-04-29 | Biosite Diagnostics, Inc. | Polyclonal libraries |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| WO1998047343A2 (en) | 1997-04-04 | 1998-10-29 | Biosite Diagnostics, Inc. | Antibodies or binding protein libraries displayed on phage, cells, or other replicatable genetic packages |
| NZ516848A (en) * | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| JP3374052B2 (ja) | 1997-07-28 | 2003-02-04 | 株式会社堀場製作所 | オゾン測定装置 |
| US5932445A (en) | 1997-11-07 | 1999-08-03 | Incyte Pharmaceuticals, Inc. | Signal peptide-containing proteins |
| US6545140B1 (en) * | 1998-07-13 | 2003-04-08 | University Of Georgia Research Foundation, Inc. | DNA encoding an avian beta-defensin and uses thereof |
| AU781460B2 (en) | 1999-02-12 | 2005-05-26 | Amgen, Inc. | Glycosylated leptin compositions and related methods |
| US6794132B2 (en) | 1999-10-02 | 2004-09-21 | Biosite, Inc. | Human antibodies |
| US7094579B2 (en) | 2002-02-13 | 2006-08-22 | Xoma Technology Ltd. | Eukaryotic signal sequences for prokaryotic expression |
| DE20207301U1 (de) | 2002-05-10 | 2002-12-19 | Eichler-Stahlberg, Alke, 93059 Regensburg | Expressionssystem für synthetische Gene in Mikroalgen |
| CN103929153B (zh) | 2013-01-11 | 2016-12-28 | 北大方正集团有限公司 | 一种倍频处理方法和装置 |
-
2002
- 2002-02-13 US US10/076,802 patent/US7094579B2/en not_active Expired - Lifetime
-
2003
- 2003-02-13 CA CA2475929A patent/CA2475929C/en not_active Expired - Fee Related
- 2003-02-13 EP EP03739833A patent/EP1481059B1/en not_active Expired - Lifetime
- 2003-02-13 EP EP08163005A patent/EP2060628B1/en not_active Expired - Lifetime
- 2003-02-13 DK DK03739833T patent/DK1481059T3/da active
- 2003-02-13 WO PCT/US2003/004791 patent/WO2003068956A1/en not_active Ceased
- 2003-02-13 DK DK08163005.5T patent/DK2060628T3/da active
- 2003-02-13 AU AU2003225578A patent/AU2003225578B2/en not_active Expired
- 2003-02-13 US US10/367,169 patent/US7396661B2/en not_active Expired - Lifetime
- 2003-02-13 DE DE60323210T patent/DE60323210D1/de not_active Expired - Lifetime
- 2003-02-13 JP JP2003568071A patent/JP4303596B2/ja not_active Expired - Lifetime
- 2003-02-13 AT AT03739833T patent/ATE406439T1/de not_active IP Right Cessation
- 2003-02-13 AT AT08163005T patent/ATE533845T1/de active
-
2008
- 2008-01-25 US US12/020,482 patent/US7977068B2/en not_active Expired - Fee Related
- 2008-01-28 US US12/021,098 patent/US7972811B2/en not_active Expired - Fee Related
-
2009
- 2009-03-17 JP JP2009065285A patent/JP5190963B2/ja not_active Expired - Fee Related
-
2011
- 2011-05-20 US US13/112,600 patent/US8476040B2/en not_active Expired - Fee Related
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