ATE406439T1 - Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken - Google Patents

Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken

Info

Publication number
ATE406439T1
ATE406439T1 AT03739833T AT03739833T ATE406439T1 AT E406439 T1 ATE406439 T1 AT E406439T1 AT 03739833 T AT03739833 T AT 03739833T AT 03739833 T AT03739833 T AT 03739833T AT E406439 T1 ATE406439 T1 AT E406439T1
Authority
AT
Austria
Prior art keywords
polypeptide
signal sequences
eukaryontic
presentation libraries
expression
Prior art date
Application number
AT03739833T
Other languages
English (en)
Inventor
Jeff Gray
Joe Buechler
Uday Veeramallu
Original Assignee
Xoma Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Technology Ltd filed Critical Xoma Technology Ltd
Application granted granted Critical
Publication of ATE406439T1 publication Critical patent/ATE406439T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT03739833T 2002-02-13 2003-02-13 Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken ATE406439T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/076,802 US7094579B2 (en) 2002-02-13 2002-02-13 Eukaryotic signal sequences for prokaryotic expression

Publications (1)

Publication Number Publication Date
ATE406439T1 true ATE406439T1 (de) 2008-09-15

Family

ID=27732544

Family Applications (2)

Application Number Title Priority Date Filing Date
AT08163005T ATE533845T1 (de) 2002-02-13 2003-02-13 Eukaryotische signalsequenzen zur polypeptid- expression und polypeptid-anzeigebibliotheken
AT03739833T ATE406439T1 (de) 2002-02-13 2003-02-13 Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT08163005T ATE533845T1 (de) 2002-02-13 2003-02-13 Eukaryotische signalsequenzen zur polypeptid- expression und polypeptid-anzeigebibliotheken

Country Status (9)

Country Link
US (5) US7094579B2 (de)
EP (2) EP2060628B1 (de)
JP (2) JP4303596B2 (de)
AT (2) ATE533845T1 (de)
AU (1) AU2003225578B2 (de)
CA (1) CA2475929C (de)
DE (1) DE60323210D1 (de)
DK (2) DK1481059T3 (de)
WO (1) WO2003068956A1 (de)

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US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
US8293503B2 (en) * 2003-10-03 2012-10-23 Promega Corporation Vectors for directional cloning
CA2541177A1 (en) * 2003-10-03 2005-09-22 Promega Corporation Vectors for directional cloning
ATE479760T1 (de) 2004-03-24 2010-09-15 Domantis Ltd Universelles signalpeptid gas1
AU2005313530B2 (en) 2004-12-07 2011-03-10 Lonza Ag Melibiose operon expression system
CN101090969B (zh) 2004-12-07 2013-01-16 隆萨股份公司 鼠李糖启动子表达系统及用途
WO2008008950A2 (en) * 2006-07-14 2008-01-17 Novozymes, Inc. Methods for producing secreted polypeptides having biological activity
GB0810154D0 (en) * 2008-06-04 2008-07-09 Avecia Biolog Ltd Expression vector
JP2012504424A (ja) 2008-10-03 2012-02-23 ゾーマ テクノロジー リミテッド トリプルタグ配列およびその使用方法
PL2401373T3 (pl) * 2009-02-25 2014-02-28 Nextera As Prezentacja fagowa pix niezależna od sekwencji sygnalnej
WO2010117420A2 (en) 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor
WO2012092323A1 (en) 2010-12-28 2012-07-05 Xoma Technology Ltd. Cell surface display using pdz domains
CA2826142A1 (en) 2011-02-03 2012-08-09 Xoma Technology Ltd. Methods and materials for enhancing functional protein expression in bacteria
CA2865033C (en) 2012-02-23 2021-11-02 Stage Cell Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
EP3578660A1 (de) 2012-07-05 2019-12-11 F. Hoffmann-La Roche AG Expressions- und sekretionssystem
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
AU2016341527B2 (en) 2015-10-22 2023-04-27 Juno Therapeutics Gmbh Methods, kits, agents and apparatuses for transduction
US10954500B2 (en) 2015-10-23 2021-03-23 Fred Hutchinson Cancer Research Center Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
CN105734061B (zh) * 2016-03-25 2019-07-23 中国农业科学院生物技术研究所 从毕赤酵母中分离的鼠李糖诱导型启动子及其应用
EP4647493A2 (de) 2017-04-27 2025-11-12 Juno Therapeutics, Inc. Oligomere partikelreagenzien und verfahren zur verwendung davon
EP3444269A1 (de) 2017-08-17 2019-02-20 National Research Council of Canada Systeme und methoden für die produktion von diphteria-giftstoff-polypeptiden
AU2018383600B2 (en) 2017-12-11 2025-10-02 Abalone Bio, Inc. Yeast display of proteins in the periplasmic space
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
IT201900006656A1 (it) 2019-05-08 2020-11-08 Salvagnini Italia Spa Macchina piegatrice per lamiere metalliche
US20230303984A1 (en) * 2020-02-25 2023-09-28 Momenta Pharmaceuticals, Inc. Enzymes for Sialylation of Glycans
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

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Also Published As

Publication number Publication date
EP1481059B1 (de) 2008-08-27
US20100009857A1 (en) 2010-01-14
DK2060628T3 (da) 2012-01-23
ATE533845T1 (de) 2011-12-15
US8476040B2 (en) 2013-07-02
CA2475929C (en) 2013-01-15
US7977068B2 (en) 2011-07-12
JP5190963B2 (ja) 2013-04-24
US20030162249A1 (en) 2003-08-28
JP2009131286A (ja) 2009-06-18
WO2003068956A1 (en) 2003-08-21
US20030228660A1 (en) 2003-12-11
EP2060628B1 (de) 2011-11-16
US20110224102A1 (en) 2011-09-15
US20080214411A1 (en) 2008-09-04
AU2003225578B2 (en) 2008-04-03
US7396661B2 (en) 2008-07-08
JP2005517407A (ja) 2005-06-16
EP1481059A4 (de) 2006-02-01
EP1481059A1 (de) 2004-12-01
CA2475929A1 (en) 2003-08-21
EP2060628A1 (de) 2009-05-20
DK1481059T3 (da) 2009-01-12
US7094579B2 (en) 2006-08-22
JP4303596B2 (ja) 2009-07-29
DE60323210D1 (en) 2008-10-09
AU2003225578A1 (en) 2003-09-04
US7972811B2 (en) 2011-07-05

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