DK1481059T3 - Eukaryote signalsekvenser for polypeptidekspression og polypeptiddisplaybiblioteker - Google Patents

Eukaryote signalsekvenser for polypeptidekspression og polypeptiddisplaybiblioteker

Info

Publication number
DK1481059T3
DK1481059T3 DK03739833T DK03739833T DK1481059T3 DK 1481059 T3 DK1481059 T3 DK 1481059T3 DK 03739833 T DK03739833 T DK 03739833T DK 03739833 T DK03739833 T DK 03739833T DK 1481059 T3 DK1481059 T3 DK 1481059T3
Authority
DK
Denmark
Prior art keywords
polypeptide
signal sequences
display libraries
eukaryotic signal
expression
Prior art date
Application number
DK03739833T
Other languages
English (en)
Inventor
Jeff Gray
Joe Buechler
Uday Kumar Veeramallu
Original Assignee
Xoma Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Technology Ltd filed Critical Xoma Technology Ltd
Application granted granted Critical
Publication of DK1481059T3 publication Critical patent/DK1481059T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK03739833T 2002-02-13 2003-02-13 Eukaryote signalsekvenser for polypeptidekspression og polypeptiddisplaybiblioteker DK1481059T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/076,802 US7094579B2 (en) 2002-02-13 2002-02-13 Eukaryotic signal sequences for prokaryotic expression
PCT/US2003/004791 WO2003068956A1 (en) 2002-02-13 2003-02-13 Eukaryotic signal sequences for polypeptide expression and polypeptide display libraries

Publications (1)

Publication Number Publication Date
DK1481059T3 true DK1481059T3 (da) 2009-01-12

Family

ID=27732544

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03739833T DK1481059T3 (da) 2002-02-13 2003-02-13 Eukaryote signalsekvenser for polypeptidekspression og polypeptiddisplaybiblioteker
DK08163005.5T DK2060628T3 (da) 2002-02-13 2003-02-13 Eukaryotiske signalsekvenser til polypeptidekspression og polypeptid-display-biblioteker

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK08163005.5T DK2060628T3 (da) 2002-02-13 2003-02-13 Eukaryotiske signalsekvenser til polypeptidekspression og polypeptid-display-biblioteker

Country Status (9)

Country Link
US (5) US7094579B2 (da)
EP (2) EP1481059B1 (da)
JP (2) JP4303596B2 (da)
AT (2) ATE533845T1 (da)
AU (1) AU2003225578B2 (da)
CA (1) CA2475929C (da)
DE (1) DE60323210D1 (da)
DK (2) DK1481059T3 (da)
WO (1) WO2003068956A1 (da)

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US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
US8293503B2 (en) 2003-10-03 2012-10-23 Promega Corporation Vectors for directional cloning
EP1847611B1 (en) * 2003-10-03 2009-09-09 Promega Corporation Rhamnose-inducible expression system
EP2172553A1 (en) * 2004-03-24 2010-04-07 Domantis Limited Gas1 universal leader
CA2589937C (en) 2004-12-07 2014-04-22 Lonza Ag Rhamnose promoter expression system
JP5080269B2 (ja) 2004-12-07 2012-11-21 ロンザ アーゲー メリビオースオペロン発現系
CN101511997B (zh) * 2006-07-14 2013-09-04 诺维信股份有限公司 用于产生具有生物学活性的分泌型多肽的方法
GB0810154D0 (en) * 2008-06-04 2008-07-09 Avecia Biolog Ltd Expression vector
US8546307B2 (en) * 2008-10-03 2013-10-01 Xoma Technology, Ltd. Triple tag sequence and methods of use thereof
PT2401373E (pt) * 2009-02-25 2013-12-16 Nextera As Apresentação em pix de fago independente de sequência sinal
WO2010117420A2 (en) 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor
EP2658971A1 (en) 2010-12-28 2013-11-06 XOMA Technology Ltd. Cell surface display using pdz domains
AU2012212047A1 (en) 2011-02-03 2013-08-22 Xoma Technology Ltd. Methods and materials for enhancing functional protein expression in bacteria
SG11201404991YA (en) 2012-02-23 2014-09-26 Stage Cell Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
MX356162B (es) * 2012-07-05 2018-05-16 Genentech Inc Sistema de expresion y secrecion.
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
ES2923755T3 (es) * 2015-10-23 2022-09-30 Fred Hutchinson Cancer Center Procedimientos para crear sistemas de proteínas de dimerización inducidos químicamente para la regulación de eventos celulares
CN105734061B (zh) * 2016-03-25 2019-07-23 中国农业科学院生物技术研究所 从毕赤酵母中分离的鼠李糖诱导型启动子及其应用
WO2018197949A1 (en) 2017-04-27 2018-11-01 Juno Therapeutics Gmbh Oligomeric particle reagents and methods of use thereof
EP3444269A1 (en) 2017-08-17 2019-02-20 National Research Council of Canada Systems and methods for the production of diphtheria toxin polypeptides
US11795579B2 (en) 2017-12-11 2023-10-24 Abalone Bio, Inc. Yeast display of proteins in the periplasmic space
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
IT201900006656A1 (it) 2019-05-08 2020-11-08 Salvagnini Italia Spa Macchina piegatrice per lamiere metalliche
EP4110391A4 (en) * 2020-02-25 2024-07-03 Momenta Pharmaceuticals Inc ENZYMES FOR SIALYLATION OF GLYCANS
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

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Also Published As

Publication number Publication date
US20030228660A1 (en) 2003-12-11
US20100009857A1 (en) 2010-01-14
CA2475929C (en) 2013-01-15
EP1481059B1 (en) 2008-08-27
CA2475929A1 (en) 2003-08-21
DK2060628T3 (da) 2012-01-23
US20110224102A1 (en) 2011-09-15
US20080214411A1 (en) 2008-09-04
DE60323210D1 (en) 2008-10-09
JP2009131286A (ja) 2009-06-18
AU2003225578B2 (en) 2008-04-03
AU2003225578A1 (en) 2003-09-04
EP2060628B1 (en) 2011-11-16
ATE406439T1 (de) 2008-09-15
ATE533845T1 (de) 2011-12-15
EP1481059A4 (en) 2006-02-01
EP1481059A1 (en) 2004-12-01
US7972811B2 (en) 2011-07-05
US8476040B2 (en) 2013-07-02
WO2003068956A1 (en) 2003-08-21
JP4303596B2 (ja) 2009-07-29
US7977068B2 (en) 2011-07-12
EP2060628A1 (en) 2009-05-20
JP5190963B2 (ja) 2013-04-24
US7396661B2 (en) 2008-07-08
JP2005517407A (ja) 2005-06-16
US20030162249A1 (en) 2003-08-28
US7094579B2 (en) 2006-08-22

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