DK1481059T3 - Eukaryote signalsekvenser for polypeptidekspression og polypeptiddisplaybiblioteker - Google Patents

Eukaryote signalsekvenser for polypeptidekspression og polypeptiddisplaybiblioteker

Info

Publication number
DK1481059T3
DK1481059T3 DK03739833T DK03739833T DK1481059T3 DK 1481059 T3 DK1481059 T3 DK 1481059T3 DK 03739833 T DK03739833 T DK 03739833T DK 03739833 T DK03739833 T DK 03739833T DK 1481059 T3 DK1481059 T3 DK 1481059T3
Authority
DK
Denmark
Prior art keywords
polypeptide
signal sequences
display libraries
eukaryotic signal
expression
Prior art date
Application number
DK03739833T
Other languages
Danish (da)
English (en)
Inventor
Jeff Gray
Joe Buechler
Uday Kumar Veeramallu
Original Assignee
Xoma Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Technology Ltd filed Critical Xoma Technology Ltd
Application granted granted Critical
Publication of DK1481059T3 publication Critical patent/DK1481059T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK03739833T 2002-02-13 2003-02-13 Eukaryote signalsekvenser for polypeptidekspression og polypeptiddisplaybiblioteker DK1481059T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/076,802 US7094579B2 (en) 2002-02-13 2002-02-13 Eukaryotic signal sequences for prokaryotic expression
PCT/US2003/004791 WO2003068956A1 (en) 2002-02-13 2003-02-13 Eukaryotic signal sequences for polypeptide expression and polypeptide display libraries

Publications (1)

Publication Number Publication Date
DK1481059T3 true DK1481059T3 (da) 2009-01-12

Family

ID=27732544

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03739833T DK1481059T3 (da) 2002-02-13 2003-02-13 Eukaryote signalsekvenser for polypeptidekspression og polypeptiddisplaybiblioteker
DK08163005.5T DK2060628T3 (da) 2002-02-13 2003-02-13 Eukaryotiske signalsekvenser til polypeptidekspression og polypeptid-display-biblioteker

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK08163005.5T DK2060628T3 (da) 2002-02-13 2003-02-13 Eukaryotiske signalsekvenser til polypeptidekspression og polypeptid-display-biblioteker

Country Status (9)

Country Link
US (5) US7094579B2 (https=)
EP (2) EP1481059B1 (https=)
JP (2) JP4303596B2 (https=)
AT (2) ATE406439T1 (https=)
AU (1) AU2003225578B2 (https=)
CA (1) CA2475929C (https=)
DE (1) DE60323210D1 (https=)
DK (2) DK1481059T3 (https=)
WO (1) WO2003068956A1 (https=)

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CA2541177A1 (en) * 2003-10-03 2005-09-22 Promega Corporation Vectors for directional cloning
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JP5745432B2 (ja) * 2009-02-25 2015-07-08 ネクステラ アーエス シグナル配列非依存性ｐＩＸファージディスプレイ
WO2010117420A2 (en) 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor
JP2014504503A (ja) 2010-12-28 2014-02-24 ゾーマ テクノロジー リミテッド Ｐｄｚドメインを用いた細胞表面提示
AU2012212047A1 (en) 2011-02-03 2013-08-22 Xoma Technology Ltd. Methods and materials for enhancing functional protein expression in bacteria
ES3011307T3 (en) 2012-02-23 2025-04-07 Juno Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
US9803191B2 (en) 2012-07-05 2017-10-31 Genentech, Inc. Expression and secretion system
EP2877589B1 (en) 2012-07-26 2024-03-06 Momenta Pharmaceuticals, Inc. Glycoproteins with anti-inflammatory properties
MX2018004875A (es) 2015-10-22 2018-08-01 Juno Therapeutics Gmbh Metodos para cultivar celulas y kits y aparatos para ello.
EP3365453A2 (en) 2015-10-22 2018-08-29 Juno Therapeutics GmbH Methods, kits, agents and apparatuses for transduction
US10954500B2 (en) 2015-10-23 2021-03-23 Fred Hutchinson Cancer Research Center Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
CN105734061B (zh) * 2016-03-25 2019-07-23 中国农业科学院生物技术研究所 从毕赤酵母中分离的鼠李糖诱导型启动子及其应用
JP7339160B2 (ja) 2017-04-27 2023-09-05 ジュノ セラピューティクス ゲーエムベーハー オリゴマー粒子試薬およびその使用方法
EP3444269A1 (en) 2017-08-17 2019-02-20 National Research Council of Canada Systems and methods for the production of diphtheria toxin polypeptides
IL275239B2 (en) 2017-12-11 2026-03-01 Abalone Bio Inc Yeast presentation of proteins in the subplasmic space
SG11202104355SA (en) 2018-10-31 2021-05-28 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
IT201900006656A1 (it) 2019-05-08 2020-11-08 Salvagnini Italia Spa Macchina piegatrice per lamiere metalliche
MX2022010467A (es) * 2020-02-25 2022-12-15 Momenta Pharmaceuticals Inc Enzimas para la sialilación de glicanos.
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
CN116284288A (zh) * 2023-02-01 2023-06-23 深圳大学 莱茵衣藻分泌导肽和转基因莱茵衣藻及其构建方法与应用

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CN103929153B (zh) 2013-01-11 2016-12-28 北大方正集团有限公司 一种倍频处理方法和装置

Also Published As

Publication number Publication date
AU2003225578A1 (en) 2003-09-04
US8476040B2 (en) 2013-07-02
CA2475929A1 (en) 2003-08-21
JP2009131286A (ja) 2009-06-18
US7094579B2 (en) 2006-08-22
US20030228660A1 (en) 2003-12-11
US20030162249A1 (en) 2003-08-28
AU2003225578B2 (en) 2008-04-03
CA2475929C (en) 2013-01-15
US20080214411A1 (en) 2008-09-04
EP1481059A1 (en) 2004-12-01
EP2060628B1 (en) 2011-11-16
US20110224102A1 (en) 2011-09-15
JP4303596B2 (ja) 2009-07-29
JP5190963B2 (ja) 2013-04-24
US7396661B2 (en) 2008-07-08
US7977068B2 (en) 2011-07-12
ATE533845T1 (de) 2011-12-15
ATE406439T1 (de) 2008-09-15
US7972811B2 (en) 2011-07-05
US20100009857A1 (en) 2010-01-14
DE60323210D1 (en) 2008-10-09
DK2060628T3 (da) 2012-01-23
JP2005517407A (ja) 2005-06-16
EP1481059A4 (en) 2006-02-01
EP2060628A1 (en) 2009-05-20
EP1481059B1 (en) 2008-08-27
WO2003068956A1 (en) 2003-08-21

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