JP2005509000A5 - - Google Patents
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- Publication number
- JP2005509000A5 JP2005509000A5 JP2003543568A JP2003543568A JP2005509000A5 JP 2005509000 A5 JP2005509000 A5 JP 2005509000A5 JP 2003543568 A JP2003543568 A JP 2003543568A JP 2003543568 A JP2003543568 A JP 2003543568A JP 2005509000 A5 JP2005509000 A5 JP 2005509000A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- liposome
- agent
- lyophilizing
- vesicle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33124801P | 2001-11-13 | 2001-11-13 | |
| US39427102P | 2002-07-09 | 2002-07-09 | |
| PCT/CA2002/001726 WO2003041681A2 (en) | 2001-11-13 | 2002-11-13 | Lipid carrier compositions with enhanced blood stability |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009242896A Division JP2010018632A (ja) | 2001-11-13 | 2009-10-21 | 増強された血中安定性を有する脂質キャリア組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005509000A JP2005509000A (ja) | 2005-04-07 |
| JP2005509000A5 true JP2005509000A5 (https=) | 2005-12-15 |
| JP4555569B2 JP4555569B2 (ja) | 2010-10-06 |
Family
ID=26987658
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003543568A Expired - Lifetime JP4555569B2 (ja) | 2001-11-13 | 2002-11-13 | 増強された血中安定性を有する脂質キャリア組成物 |
| JP2009242896A Withdrawn JP2010018632A (ja) | 2001-11-13 | 2009-10-21 | 増強された血中安定性を有する脂質キャリア組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009242896A Withdrawn JP2010018632A (ja) | 2001-11-13 | 2009-10-21 | 増強された血中安定性を有する脂質キャリア組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20050118250A1 (https=) |
| EP (1) | EP1443900B1 (https=) |
| JP (2) | JP4555569B2 (https=) |
| AU (1) | AU2002340669A1 (https=) |
| CA (1) | CA2467064C (https=) |
| ES (1) | ES2387886T3 (https=) |
| PT (1) | PT1443900E (https=) |
| WO (1) | WO2003041681A2 (https=) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2467064C (en) * | 2001-11-13 | 2011-02-08 | Murray Webb | Lipid carrier compositions with enhanced blood stability |
| JP4874547B2 (ja) * | 2002-11-26 | 2012-02-15 | ギリアード サイエンシーズ, インコーポレイテッド | 勾配によるリポソームへの薬物充填方法 |
| US8980310B2 (en) * | 2002-12-31 | 2015-03-17 | Bharat Serums and Vaccines, Ltd. | Non-pegylated long-circulating liposomes |
| EP1643972A4 (en) * | 2003-06-27 | 2010-01-20 | Smithkline Beecham Corp | STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD |
| CA2928387A1 (en) | 2004-05-03 | 2005-11-17 | Merrimack Pharmaceuticals, Inc. | Drug delivery liposomes containing anionic polyols or anionic sugars |
| JP4885715B2 (ja) * | 2004-06-01 | 2012-02-29 | テルモ株式会社 | イリノテカン製剤 |
| JP4715133B2 (ja) * | 2004-08-26 | 2011-07-06 | コニカミノルタエムジー株式会社 | 抗腫瘍リポソーム製剤およびその製造方法 |
| US20090285878A1 (en) * | 2004-11-05 | 2009-11-19 | Tekmira Pharmaceuticals Corporation | Compositions and methods for stabilizing liposomal drug formulations |
| US20110020434A1 (en) * | 2005-09-02 | 2011-01-27 | O'halloran Thomas V | Nanoparticle arsenic-platinum compositions |
| US20070154403A1 (en) * | 2006-01-05 | 2007-07-05 | Thomas Skold | Oral, Pulmonary and Transmucosal Delivery Composition |
| AU2007235463B2 (en) * | 2006-03-30 | 2012-11-22 | The Research Foundation Of State University Of New York | Compositions of less immunogenic and long-circulating protein-lipid complexes |
| JP2009545621A (ja) * | 2006-08-02 | 2009-12-24 | ユナイテッド セラピューティクス コーポレーション | ウィルス感染症のリポソーム処置 |
| US20090196917A1 (en) * | 2008-02-01 | 2009-08-06 | University Of Kentucky Research Foundation | Liposomal Formulations of Hydrophobic Lactone Drugs in the Presence of Metal Ions |
| US20090252785A1 (en) * | 2008-03-26 | 2009-10-08 | University Of Oxford | Endoplasmic reticulum targeting liposomes |
| EP2123258A1 (en) | 2008-05-23 | 2009-11-25 | Liplasome Pharma A/S | Liposomes for drug delivery |
| AR076634A1 (es) * | 2008-11-21 | 2011-06-29 | Medgenesis Therapeutix Inc | Composiciones y metodo para tratar desordenes del sistema nervioso central |
| KR20120059447A (ko) * | 2009-03-27 | 2012-06-08 | 더 챈슬러 마스터즈 앤드 스칼라스 오브 더 유니버시티 오브 옥스포드 | 콜레스테롤 수준 저하 리포좀 |
| ES2593027T3 (es) * | 2009-03-30 | 2016-12-05 | Eisai R&D Management Co., Ltd. | Composición liposomal |
| EP2415464B1 (en) | 2009-03-30 | 2017-05-10 | Eisai R&D Management Co., Ltd. | Method for producing liposome composition |
| DK177532B1 (en) * | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
| DK177529B1 (en) | 2009-10-23 | 2013-09-08 | Bio Bedst Aps | Liposomes with improved storage stability |
| PT2508170E (pt) * | 2009-12-03 | 2015-10-16 | Shanghai Hengrui Pharm Co Ltd | Lipossoma de irinotecano ou o seu cloridrato e seu método de preparação |
| JP2013529638A (ja) * | 2010-06-19 | 2013-07-22 | ウェスタン ユニバーシティ オブ ヘルス サイエンス | Peg化リポソーム封入糖ペプチド抗生物質の新規製剤 |
| ITMI20111271A1 (it) * | 2011-07-08 | 2013-01-09 | Giuseppe Milani | Prodotto alimentare del tipo da conservare e consumare refrigerato o congelato |
| EP3572071A1 (en) * | 2011-10-21 | 2019-11-27 | Jazz Pharmaceuticals Research LLC | Lyophilized liposomes |
| PL2861214T3 (pl) * | 2012-06-14 | 2021-02-08 | Universität Bern | Liposomy przystosowane do leczenia zakażeń bakteryjnych |
| US9801874B2 (en) | 2012-11-20 | 2017-10-31 | Spectrum Pharmaceuticals | Method for the preparation of liposome encapsulated vincristine for therapeutic use |
| WO2014153114A1 (en) * | 2013-03-14 | 2014-09-25 | Fred Hutchinson Cancer Research Center | Compositions and methods to modify cells for therapeutic objectives |
| US9993427B2 (en) | 2013-03-14 | 2018-06-12 | Biorest Ltd. | Liposome formulation and manufacture |
| RS61273B1 (sr) * | 2014-04-30 | 2021-01-29 | Fujifilm Corp | Lipozomska kompozicija i postupak za njeno dobijanje |
| TWI678213B (zh) | 2015-07-22 | 2019-12-01 | 美商史倍壯製藥公司 | 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物 |
| MX382522B (es) | 2015-10-16 | 2025-03-13 | Ipsen Biopharm Ltd | Composiciones farmaceuticas estabilizantes de camptotecina. |
| US10188749B2 (en) | 2016-04-14 | 2019-01-29 | Fred Hutchinson Cancer Research Center | Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers |
| US12029724B2 (en) | 2016-04-28 | 2024-07-09 | Eisai R&D Management Co., Ltd. | Method for inhibiting tumor growth |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2018266111B2 (en) | 2017-05-08 | 2024-11-07 | Flagship Pioneering Innovations V, Inc. | Compositions for facilitating membrane fusion and uses thereof |
| US10459751B2 (en) * | 2017-06-30 | 2019-10-29 | ATI Technologies ULC. | Varying firmware for virtualized device |
| CN111629715A (zh) | 2018-01-18 | 2020-09-04 | 弗莱德哈钦森癌症研究中心 | 通过调节细胞活化状态改变体内免疫细胞的炎症状态 |
| US11590079B2 (en) * | 2018-01-18 | 2023-02-28 | EndoProtech, Inc. | Treating microvascular dysfunction |
| MX2021001820A (es) * | 2018-09-14 | 2021-04-28 | Pharmosa Biopharm Inc | Composicion farmaceutica para la liberacion controlada de farmacos acidos debiles y usos de los mismos. |
| EP3856198A4 (en) | 2018-09-25 | 2022-06-22 | Celator Pharmaceuticals, Inc. | Low-intensity treatment of hematological disorders |
| EP4137527A1 (en) | 2018-12-04 | 2023-02-22 | TIEN, Der-Yang | Stereocomplexes for the delivery of anti-cancer agents |
| CA3119037A1 (en) | 2018-12-11 | 2020-06-18 | Disruption Labs Inc. | Compositions for the delivery of therapeutic agents and methods of use and making thereof |
| CN113473980A (zh) | 2019-03-01 | 2021-10-01 | 弗拉梅尔爱尔兰有限公司 | 在进食状态下具有改善的药代动力学的γ-羟基丁酸酯组合物 |
| US11083705B2 (en) | 2019-07-26 | 2021-08-10 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| US12036204B2 (en) | 2019-07-26 | 2024-07-16 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| JP2023535790A (ja) | 2020-07-28 | 2023-08-21 | ジャズ ファーマシューティカルズ アイルランド リミテッド | 縮合二環式raf阻害薬及びその使用方法 |
| WO2022023450A1 (en) | 2020-07-28 | 2022-02-03 | Jazz Pharmaceuticals Ireland Limited | Chiral synthesis of fused bicyclic raf inhibitors |
| US11980636B2 (en) | 2020-11-18 | 2024-05-14 | Jazz Pharmaceuticals Ireland Limited | Treatment of hematological disorders |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| WO2024209267A2 (en) | 2023-04-03 | 2024-10-10 | Jazz Pharmaceuticals Ireland Limited | Modulators of nanoparticle uptake |
| TW202543582A (zh) * | 2024-02-29 | 2025-11-16 | 美商葛里柯麥公司 | 脂質體調配物及其使用及製備方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5077056A (en) * | 1984-08-08 | 1991-12-31 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
| DE3686025T2 (de) * | 1985-05-22 | 1993-01-07 | Liposome Technology Inc | Verfahren und system zum einatmen von liposomen. |
| IE58981B1 (en) * | 1985-10-15 | 1993-12-15 | Vestar Inc | Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles |
| JPH0617309B2 (ja) * | 1985-11-29 | 1994-03-09 | 株式会社ビタミン研究所 | アドリアマイシン包埋リポソ−ム製剤 |
| US4927571A (en) * | 1987-05-18 | 1990-05-22 | Liposome Technology, Inc. | Preparation of injectable doxorubicin/liposome suspension |
| AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
| US4915951A (en) * | 1987-12-03 | 1990-04-10 | California Institute Of Technology | Cryoprotective reagent |
| WO1990003795A1 (en) * | 1988-10-05 | 1990-04-19 | Vestar, Inc. | Method of making liposomes with improved stability during drying |
| US5843473A (en) * | 1989-10-20 | 1998-12-01 | Sequus Pharmaceuticals, Inc. | Method of treatment of infected tissues |
| US5225212A (en) * | 1989-10-20 | 1993-07-06 | Liposome Technology, Inc. | Microreservoir liposome composition and method |
| IS1685B (is) * | 1990-12-11 | 1998-02-24 | Bracco International B.V. | Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum |
| GB9111611D0 (en) | 1991-05-30 | 1991-07-24 | Sandoz Ltd | Liposomes |
| US5648532A (en) * | 1993-06-03 | 1997-07-15 | The Regents Of The University Of California | Compositions for boron neutron capture therapy and methods thereof |
| US5415869A (en) * | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
| PT101422B (pt) | 1993-12-06 | 1997-06-30 | Ineti Inst Biotec Q F E Tecnol | Formulacoes lipossomicas contendo vidarabina e/ou derivados, com indice terapeutico elevado e processo para a sua preparacao |
| US6139871A (en) * | 1995-07-26 | 2000-10-31 | The University Of British Columbia | Liposome compositions and methods for the treatment of atherosclerosis |
| JPH07316041A (ja) | 1994-03-28 | 1995-12-05 | Dai Ichi Seiyaku Co Ltd | 保持容量を向上させたリポソーム |
| CN1148336A (zh) | 1994-03-28 | 1997-04-23 | 第一制药株式会社 | 增大包封量的脂质体 |
| AU714043B2 (en) * | 1994-10-03 | 1999-12-16 | Infectio Recherche Inc. | Liposome-formulations for treatment of viral diseases |
| CA2263455C (en) * | 1996-08-23 | 2002-10-29 | Sequus Pharmaceuticals, Inc. | Liposomes containing a cisplatin compound |
| US6120800A (en) * | 1997-09-25 | 2000-09-19 | Nexstar Pharmaceuticals, Inc. | Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties |
| AU756109B2 (en) | 1997-12-04 | 2003-01-02 | Hadasit Medical Research Services & Development Company Ltd | Methods for antitumor therapy |
| JPH11171772A (ja) | 1997-12-11 | 1999-06-29 | Sankyo Co Ltd | 抗腫瘍薬のリポソーム化製剤 |
| AU4196099A (en) | 1998-05-21 | 1999-12-06 | Isis Pharmaceuticals, Inc. | Long-circulating liposomal compositions |
| US6200598B1 (en) * | 1998-06-18 | 2001-03-13 | Duke University | Temperature-sensitive liposomal formulation |
| US6270806B1 (en) | 1999-03-03 | 2001-08-07 | Elan Pharma International Limited | Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions |
| JP2001026544A (ja) | 1999-05-11 | 2001-01-30 | Sankyo Co Ltd | 脂溶性抗腫瘍薬のリポソーム製剤 |
| DE60014093T2 (de) * | 1999-07-16 | 2005-02-03 | Alza Corp., Mountain View | Liposomzusammensetzung mit Schutz vor Gefrier-/Aufbau-Schaden |
| JP2001302496A (ja) | 2000-04-14 | 2001-10-31 | Takeda Chem Ind Ltd | リポソーム製剤 |
| JP4540287B2 (ja) * | 2001-03-02 | 2010-09-08 | 日油株式会社 | ポリアルキレンオキシド修飾リン脂質の製造方法 |
| DE60208454T2 (de) * | 2001-03-02 | 2006-09-07 | Nof Corp. | Polyalkylenoxid-modifizierte Phospholipide und Verfahren zu ihrer Herstellung |
| CA2467064C (en) * | 2001-11-13 | 2011-02-08 | Murray Webb | Lipid carrier compositions with enhanced blood stability |
-
2002
- 2002-11-13 CA CA2467064A patent/CA2467064C/en not_active Expired - Lifetime
- 2002-11-13 PT PT02774210T patent/PT1443900E/pt unknown
- 2002-11-13 US US10/495,666 patent/US20050118250A1/en not_active Abandoned
- 2002-11-13 ES ES02774210T patent/ES2387886T3/es not_active Expired - Lifetime
- 2002-11-13 AU AU2002340669A patent/AU2002340669A1/en not_active Abandoned
- 2002-11-13 US US10/294,474 patent/US8518437B2/en active Active
- 2002-11-13 EP EP02774210A patent/EP1443900B1/en not_active Expired - Lifetime
- 2002-11-13 WO PCT/CA2002/001726 patent/WO2003041681A2/en not_active Ceased
- 2002-11-13 JP JP2003543568A patent/JP4555569B2/ja not_active Expired - Lifetime
-
2009
- 2009-10-21 JP JP2009242896A patent/JP2010018632A/ja not_active Withdrawn
-
2010
- 2010-09-16 US US12/884,098 patent/US20110002982A1/en not_active Abandoned
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