JP2005504718A5 - - Google Patents
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- JP2005504718A5 JP2005504718A5 JP2002559071A JP2002559071A JP2005504718A5 JP 2005504718 A5 JP2005504718 A5 JP 2005504718A5 JP 2002559071 A JP2002559071 A JP 2002559071A JP 2002559071 A JP2002559071 A JP 2002559071A JP 2005504718 A5 JP2005504718 A5 JP 2005504718A5
- Authority
- JP
- Japan
- Prior art keywords
- capsular polysaccharide
- meningococcal
- immune composition
- adjuvant
- multivalent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 150000004676 glycans Polymers 0.000 claims 15
- 229920001282 polysaccharide Polymers 0.000 claims 15
- 239000005017 polysaccharide Substances 0.000 claims 15
- 150000004804 polysaccharides Polymers 0.000 claims 15
- 229960005486 vaccines Drugs 0.000 claims 9
- 230000000240 adjuvant Effects 0.000 claims 6
- 239000002671 adjuvant Substances 0.000 claims 6
- 102000014914 Carrier Proteins Human genes 0.000 claims 4
- 108010078791 Carrier Proteins Proteins 0.000 claims 4
- WNROFYMDJYEPJX-UHFFFAOYSA-K Aluminium hydroxide Chemical group [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 2
- ILRRQNADMUWWFW-UHFFFAOYSA-K Aluminium phosphate Chemical group O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 claims 2
- 241000588650 Neisseria meningitidis Species 0.000 claims 2
- 229960003983 diphtheria toxoid Drugs 0.000 claims 2
- 229940052778 Neisseria meningitidis Drugs 0.000 claims 1
- 201000009910 diseases by infectious agent Diseases 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
Claims (17)
- ２、３、または４つの別個のタンパク質−多糖複合体を含み、各複合体が、１以上の担体タンパク質に結合した２以上の髄膜炎菌血清群由来の莢膜多糖を含むことを特徴とする免疫組成物。
- 前記莢膜多糖が、髄膜炎菌血清群Ａ、Ｃ、Ｗ−１３５、およびＹ由来の莢膜多糖より成る群から選択されることを特徴とする請求項１記載の免疫組成物。
- 前記莢膜多糖が、髄膜炎菌血清群ＡおよびＣ由来の莢膜多糖であることを特徴とする請求項１記載の免疫組成物。
- 前記莢膜多糖が、髄膜炎菌血清群Ａ、Ｃ，Ａ−１３５、およびＣ由来の莢膜多糖であることを特徴とする請求項１記載の免疫組成物。
- 前記担体タンパク質がジフテリアトキソイドであることを特徴とする請求項１記載の免疫組成物。
- アジュバントをさらに含むことを特徴とする請求項１記載の免疫組成物。
- 前記アジュバントが水酸化アルミニウムであることを特徴とする請求項５記載の免疫組成物。
- 前記アジュバントがリン酸アルミニウムであることを特徴とする請求項５記載の免疫組成物。
- 髄膜炎菌の莢膜多糖に対する免疫応答を誘導するためにヒトまたは動物に投与されることを特徴とする請求項１記載の免疫組成物。
- 免疫学的効果量の２から４つの別個のタンパク質−多糖複合体から成り、各複合体が担体タンパク質に結合した異なる莢膜多糖を含み、各莢膜多糖が血清群Ａ、Ｃ、Ｗ−１３５、およびＹ由来の莢膜多糖より成る群から選択されることを特徴とする多価髄膜炎菌ワクチン。
- 前記莢膜多糖が、髄膜炎菌血清群ＡおよびＣから調製されることを特徴とする請求項１０記載の多価髄膜炎菌ワクチン。
- 前記莢膜多糖が、髄膜炎菌血清群Ａ、Ｃ，Ａ−１３５、およびＣから調製されることを特徴とする請求項１０記載の多価髄膜炎菌ワクチン。
- 前記担体タンパク質がジフテリアトキソイドであることを特徴とする請求項１０記載の多価髄膜炎菌ワクチン。
- アジュバントをさらに含むことを特徴とする請求項１０記載の多価髄膜炎菌ワクチン。
- 前記アジュバントが水酸化アルミニウムであることを特徴とする請求項１４記載の多価髄膜炎菌ワクチン。
- 前記アジュバントがリン酸アルミニウムであることを特徴とする請求項５記載の多価髄膜炎菌ワクチン。
- 髄膜炎菌に感染しやすいヒトまたは動物を防御するためにヒトまたは動物に投与されることを特徴とする請求項１０記載の多価髄膜炎菌ワクチン。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26343501P | 2001-01-23 | 2001-01-23 | |
| PCT/US2002/001963 WO2002058737A2 (en) | 2001-01-23 | 2002-01-22 | Multivalent meningococcal polysaccharide-protein conjugate vaccine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011089891A Division JP5795721B2 (ja) | 2001-01-23 | 2011-04-14 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005504718A JP2005504718A (ja) | 2005-02-17 |
| JP2005504718A5 true JP2005504718A5 (ja) | 2005-12-22 |
Family
ID=23001755
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002559071A Pending JP2005504718A (ja) | 2001-01-23 | 2002-01-22 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2011089891A Expired - Lifetime JP5795721B2 (ja) | 2001-01-23 | 2011-04-14 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2013257766A Pending JP2014043474A (ja) | 2001-01-23 | 2013-12-13 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2013257767A Pending JP2014043475A (ja) | 2001-01-23 | 2013-12-13 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2014004347A Pending JP2014065745A (ja) | 2001-01-23 | 2014-01-14 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2016081902A Pending JP2016128526A (ja) | 2001-01-23 | 2016-04-15 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011089891A Expired - Lifetime JP5795721B2 (ja) | 2001-01-23 | 2011-04-14 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2013257766A Pending JP2014043474A (ja) | 2001-01-23 | 2013-12-13 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2013257767A Pending JP2014043475A (ja) | 2001-01-23 | 2013-12-13 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2014004347A Pending JP2014065745A (ja) | 2001-01-23 | 2014-01-14 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| JP2016081902A Pending JP2016128526A (ja) | 2001-01-23 | 2016-04-15 | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
Country Status (38)
| Country | Link |
|---|---|
| US (9) | US8722062B2 (ja) |
| EP (3) | EP2332581B1 (ja) |
| JP (6) | JP2005504718A (ja) |
| KR (2) | KR100947751B1 (ja) |
| CN (1) | CN100556459C (ja) |
| AP (1) | AP1897A (ja) |
| AU (2) | AU2007216743A1 (ja) |
| BE (3) | BE2012C050I2 (ja) |
| BR (1) | BRPI0206672B8 (ja) |
| CA (1) | CA2435681C (ja) |
| CR (1) | CR7035A (ja) |
| CY (2) | CY1113072T1 (ja) |
| DK (2) | DK1355673T3 (ja) |
| EA (1) | EA006947B1 (ja) |
| EC (1) | ECSP034701A (ja) |
| ES (3) | ES2892316T3 (ja) |
| FR (3) | FR12C0072I2 (ja) |
| GE (1) | GEP20053691B (ja) |
| HR (1) | HRP20030598B1 (ja) |
| HU (2) | HU230490B1 (ja) |
| IL (3) | IL157060A0 (ja) |
| IS (1) | IS6881A (ja) |
| LT (1) | LT5177B (ja) |
| LU (1) | LU92108I2 (ja) |
| LV (1) | LV13128B (ja) |
| MX (2) | MXPA03006561A (ja) |
| NO (1) | NO20033816L (ja) |
| NZ (2) | NZ622900A (ja) |
| OA (1) | OA12590A (ja) |
| PL (1) | PL226184B1 (ja) |
| PT (2) | PT2332581E (ja) |
| RO (1) | RO122761B1 (ja) |
| SI (1) | SI21352A (ja) |
| TN (1) | TNSN03041A1 (ja) |
| UA (1) | UA92579C2 (ja) |
| WO (1) | WO2002058737A2 (ja) |
| YU (1) | YU66103A (ja) |
| ZA (1) | ZA200306176B (ja) |
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| AU2003299501A1 (en) * | 2002-05-16 | 2004-05-04 | Aventis Pasteur, Inc. | Animal component free meningococcal polysaccharide fermentation and seedbank development |
| AU2003257003A1 (en) * | 2002-07-30 | 2004-02-16 | Baxter Healthcare S.A. | Chimeric multivalent polysaccharide conjugate vaccines |
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