JP2005503125A5 - - Google Patents
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- JP2005503125A5 JP2005503125A5 JP2002582208A JP2002582208A JP2005503125A5 JP 2005503125 A5 JP2005503125 A5 JP 2005503125A5 JP 2002582208 A JP2002582208 A JP 2002582208A JP 2002582208 A JP2002582208 A JP 2002582208A JP 2005503125 A5 JP2005503125 A5 JP 2005503125A5
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- JP
- Japan
- Prior art keywords
- nucleic acid
- acid sequence
- seq
- protein
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000007523 nucleic acids Chemical class 0.000 claims 53
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 35
- 108090000623 proteins and genes Proteins 0.000 claims 20
- 102000004169 proteins and genes Human genes 0.000 claims 18
- 125000003275 alpha amino acid group Chemical group 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 16
- 102000039446 nucleic acids Human genes 0.000 claims 16
- 108010000700 Acetolactate synthase Proteins 0.000 claims 12
- 238000000034 method Methods 0.000 claims 9
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 108010030975 Polyketide Synthases Proteins 0.000 claims 7
- 244000005700 microbiome Species 0.000 claims 7
- 102000004243 Tubulin Human genes 0.000 claims 5
- 108090000704 Tubulin Proteins 0.000 claims 5
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 4
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- BCIHMWNOJJYBSJ-UHFFFAOYSA-N 2-pyrimidin-2-yloxybenzoic acid Chemical compound OC(=O)C1=CC=CC=C1OC1=NC=CC=N1 BCIHMWNOJJYBSJ-UHFFFAOYSA-N 0.000 claims 3
- CAAMSDWKXXPUJR-UHFFFAOYSA-N 3,5-dihydro-4H-imidazol-4-one Chemical compound O=C1CNC=N1 CAAMSDWKXXPUJR-UHFFFAOYSA-N 0.000 claims 3
- 239000003112 inhibitor Substances 0.000 claims 3
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 claims 3
- 230000002103 transcriptional effect Effects 0.000 claims 3
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 claims 2
- 101710123462 Bleomycin resistance protein Proteins 0.000 claims 2
- 235000021294 Docosapentaenoic acid Nutrition 0.000 claims 2
- 102000009114 Fatty acid desaturases Human genes 0.000 claims 2
- 108010087894 Fatty acid desaturases Proteins 0.000 claims 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 2
- 235000021342 arachidonic acid Nutrition 0.000 claims 2
- 229940114079 arachidonic acid Drugs 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 2
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 2
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 2
- 230000006801 homologous recombination Effects 0.000 claims 2
- 238000002744 homologous recombination Methods 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 230000035945 sensitivity Effects 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 230000009466 transformation Effects 0.000 claims 2
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 claims 1
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 claims 1
- 241001467333 Thraustochytriaceae Species 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28411601P | 2001-04-16 | 2001-04-16 | |
| PCT/US2002/012040 WO2002083869A2 (en) | 2001-04-16 | 2002-04-16 | Product and process for transformation of thraustochytriales microorganisms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010019881A Division JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005503125A JP2005503125A (ja) | 2005-02-03 |
| JP2005503125A5 true JP2005503125A5 (enExample) | 2005-12-22 |
| JP4536324B2 JP4536324B2 (ja) | 2010-09-01 |
Family
ID=23088908
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582208A Expired - Fee Related JP4536324B2 (ja) | 2001-04-16 | 2002-04-16 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2010019881A Expired - Lifetime JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2012215905A Withdrawn JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2015253726A Expired - Fee Related JP6211577B2 (ja) | 2001-04-16 | 2015-12-25 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010019881A Expired - Lifetime JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2012215905A Withdrawn JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2015253726A Expired - Fee Related JP6211577B2 (ja) | 2001-04-16 | 2015-12-25 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7001772B2 (enExample) |
| EP (3) | EP2325319B1 (enExample) |
| JP (4) | JP4536324B2 (enExample) |
| CN (3) | CN101760469A (enExample) |
| AT (1) | ATE533844T1 (enExample) |
| AU (1) | AU2002250592C1 (enExample) |
| CA (1) | CA2443908C (enExample) |
| ES (3) | ES2698473T3 (enExample) |
| TW (3) | TWI377253B (enExample) |
| WO (1) | WO2002083869A2 (enExample) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US7211418B2 (en) | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| TWI377253B (en) * | 2001-04-16 | 2012-11-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7211656B2 (en) † | 2002-01-30 | 2007-05-01 | Abbott Laboratories | Desaturase genes, enzymes encoded thereby, and uses thereof |
| DK1572994T3 (da) * | 2002-12-20 | 2007-05-29 | Chromagenics Bv | Midler og fremgangsmåder til fremstilling af en protein gennem chromatinåbnere, som kan göre chromatin mere tilgængeligt for transkriptionsfaktorer |
| US7208590B2 (en) * | 2003-07-15 | 2007-04-24 | Abbott Laboratories | Genes involved in polyketide synthase pathways and uses thereof |
| ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| CA3056110C (en) | 2004-04-22 | 2020-07-14 | Surinder Pal Singh | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| US8999667B2 (en) * | 2004-11-08 | 2015-04-07 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20060195935A1 (en) | 2004-11-08 | 2006-08-31 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| BRPI0517380A (pt) * | 2004-11-08 | 2008-10-07 | Chromagenics Bv | molécula de dna, cassete de expressão, célula hospedeira, e, métodos para gerar uma célula hospedeira que expressa um polipeptìdeo de interesse e para produzir um polipeptìdeo de interesse |
| US20100136616A1 (en) * | 2004-11-08 | 2010-06-03 | Chromagenics B.V. | Selection of Host Cells Expressing Protein at High Levels |
| NZ553700A (en) * | 2004-11-08 | 2010-09-30 | Chromagenics Bv | Selection of host cells expressing protein at high levels using a selectable marker with a non-optimal start codon |
| JP4796786B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
| JP4796787B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
| ES2909600T3 (es) | 2005-06-07 | 2022-05-09 | Dsm Nutritional Products Ag | Microorganismos eucarióticos para producir lípidos y antioxidantes |
| CA2624661C (en) | 2005-11-23 | 2015-06-30 | E.I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| EP1818411A1 (en) * | 2006-02-13 | 2007-08-15 | Lonza AG | Process for the preparation of optically active chiral amines |
| WO2007106903A2 (en) | 2006-03-15 | 2007-09-20 | Martek Biosciences Corporation | Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems |
| CA2649118A1 (en) * | 2006-04-11 | 2007-10-25 | Martek Biosciences Corporation | Food products comprising long chain polyunsaturated fatty acids and methods for preparing the same |
| PL2034973T5 (pl) | 2006-06-22 | 2023-02-20 | Dsm Ip Assets B.V. | Kapsułkowane kompozycje nietrwałych związków i sposoby ich wytwarzania |
| US9023616B2 (en) * | 2006-08-01 | 2015-05-05 | Dsm Nutritional Products Ag | Oil producing microbes and method of modification thereof |
| EP2415360A3 (en) | 2006-08-29 | 2012-02-29 | Martek Biosciences Corporation | Use of DPA(n-6) oils in infant formula |
| RU2009111266A (ru) | 2006-08-29 | 2010-10-10 | Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) | Синтез жирных кислот |
| KR100860111B1 (ko) * | 2006-10-02 | 2008-09-25 | 인제대학교 산학협력단 | 신규 미생물 트라우스토카이트리움 에스피.케이제이에스-1, 바실러스 폴리퍼멘티쿠스 케이제이에스-2 및 이들과 바실러스 리케니포르미스를 포함하고 있는 사료첨가제 및 사료 |
| UA102059C2 (uk) | 2006-10-23 | 2013-06-10 | Е.І. Дю Пон Де Немур Енд Компані | Дельта-8 десатураза та її застосування для одержання поліненасичених жирних кислот |
| US7790156B2 (en) | 2007-04-10 | 2010-09-07 | E. I. Du Pont De Nemours And Company | Δ-8 desaturases and their use in making polyunsaturated fatty acids |
| US7794701B2 (en) | 2007-04-16 | 2010-09-14 | E.I. Du Pont De Nemours And Company | Δ-9 elongases and their use in making polyunsaturated fatty acids |
| US8957280B2 (en) | 2007-05-03 | 2015-02-17 | E. I. Du Pont De Nemours And Company | Delta-5 desaturases and their use in making polyunsaturated fatty acids |
| US20090023808A1 (en) * | 2007-06-29 | 2009-01-22 | Martek Biosciences Corporation | Production and Purification of Esters of Polyunsaturated Fatty Acids |
| EA019387B1 (ru) | 2007-09-12 | 2014-03-31 | Мартек Биосайнсиз Корпорейшн | Способ получения биологического масла и его использование в способе получения биодизеля |
| US20110076379A1 (en) * | 2008-06-13 | 2011-03-31 | Means Michael M | High omega saturated fat free meat products |
| DK2358882T3 (da) | 2008-11-18 | 2017-11-06 | Commw Scient Ind Res Org | Enzymer og fremgangsmåder til fremstilling af omega-3 fedtsyrer |
| EP2358862B1 (en) | 2008-12-18 | 2017-08-02 | E. I. du Pont de Nemours and Company | Reducing byproduction of malonates in a fermentation process |
| JP5415896B2 (ja) | 2009-01-29 | 2014-02-12 | Jfeスチール株式会社 | インダイレクトスポット溶接方法 |
| CN102648207A (zh) | 2009-03-16 | 2012-08-22 | 马太克生物科学公司 | 在网粘菌门微生物中产生蛋白质 |
| ES2717102T3 (es) | 2009-03-19 | 2019-06-19 | Dsm Ip Assets Bv | Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos |
| US8207363B2 (en) | 2009-03-19 | 2012-06-26 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| JP5931721B2 (ja) | 2009-06-16 | 2016-06-08 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company | アシルCoAリゾリン脂質アシルトランスフェラーゼの発現による長鎖オメガ−3及びオメガ−6多価不飽和脂肪酸生合成の改良 |
| EP2966169A1 (en) * | 2009-09-24 | 2016-01-13 | Kyushu University | Method for transforming stramenopiles |
| EA030095B1 (ru) * | 2009-12-28 | 2018-06-29 | ДиЭсЭм АйПи АССЕТС Б.В. | Получение белка гемагглютинин-нейраминидазы в микроводорослях |
| EP3213766A1 (en) | 2009-12-28 | 2017-09-06 | Merial Ltd. | Recombinant ndv antigen and uses thereof |
| CA2785971C (en) * | 2009-12-28 | 2019-02-12 | Dsm Ip Assets B.V. | Production of heterologous polypeptides in microalgae, microalgal extracellular bodies, compositions, and methods of making and uses thereof |
| CN102906270B (zh) * | 2009-12-28 | 2016-06-22 | Dsmip资产公司 | 在木糖上生长的重组破囊壶菌和其组合物、制备方法及用途 |
| EP2519625B1 (en) * | 2009-12-28 | 2018-09-26 | DSM IP Assets B.V. | Recombinant thraustochytrids that grow on sucrose, and compositions, methods of making, and uses thereof |
| CA2993690C (en) | 2010-01-19 | 2022-03-22 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| WO2011112945A2 (en) | 2010-03-12 | 2011-09-15 | Merial Limited | Foot and mouth disease virus recombinant vaccines and uses thereof |
| JP2013535988A (ja) | 2010-08-26 | 2013-09-19 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 変異hpggモチーフおよびhdashモチーフδ5デサチュラーゼおよび多価不飽和脂肪酸の製造におけるそれらの使用 |
| JP5963749B2 (ja) | 2010-08-26 | 2016-08-03 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company | 変異δ9エロンガーゼおよび多価不飽和脂肪酸の製造におけるそれらの使用 |
| US9133463B2 (en) * | 2011-03-07 | 2015-09-15 | Dsm Nutritional Products Ag | Engineering microorganisms |
| MX342216B (es) | 2011-07-21 | 2016-09-20 | Dsm Ip Assets Bv | Composiciones de acidos grasos. |
| US8950312B2 (en) * | 2011-08-17 | 2015-02-10 | Lwrc International Llc | Bolt carrier and bolt for gas operated firearms |
| US8844424B2 (en) * | 2011-08-17 | 2014-09-30 | Lwrc International Llc | Bolt carrier and bolt for gas operated firearms |
| US8946460B2 (en) | 2012-06-15 | 2015-02-03 | Commonwealth Scientific And Industrial Research Organisation | Process for producing polyunsaturated fatty acids in an esterified form |
| WO2013192002A1 (en) | 2012-06-19 | 2013-12-27 | E. I. Du Pont De Nemours And Company | IMPROVED PRODUCTION OF POLYUNSATURATED FATTY ACIDS BY COEXPRESSION OF ACYL-CoA:LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASES AND PHOSPHOLIPID:DIACYLGLYCEROL ACYLTRANSFERASES |
| AU2014229307B2 (en) | 2013-03-13 | 2017-08-31 | Dsm Nutritional Products Ag | Engineering microorganisms |
| WO2015196250A1 (en) | 2014-06-27 | 2015-12-30 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising docosapentaenoic acid |
| KR102386838B1 (ko) | 2013-12-18 | 2022-04-15 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 장쇄 다중불포화 지방산을 포함하는 지질 |
| CN105567715B (zh) * | 2014-10-17 | 2021-06-29 | 丰益(上海)生物技术研发中心有限公司 | 裂殖壶菌α-微管蛋白相关序列及其应用 |
| EP3265567B1 (en) | 2015-03-02 | 2020-07-29 | Conagen Inc. | Regulatory elements from labyrinthulomycetes microorganisms |
| AR104042A1 (es) | 2015-03-26 | 2017-06-21 | Mara Renewables Corp | Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto |
| EP3302032B1 (en) | 2015-06-06 | 2021-12-15 | DSM IP Assets B.V. | Production of polyunsaturated fatty acids (pufas) using a novel modular docosahexaenoic acid (dha) synthase |
| US10542961B2 (en) | 2015-06-15 | 2020-01-28 | The Research Foundation For The State University Of New York | System and method for infrasonic cardiac monitoring |
| CN122256151A (zh) * | 2015-07-13 | 2026-06-23 | 玛拉可再生能源公司 | 增强木糖的微藻代谢 |
| IL241462A0 (en) | 2015-09-10 | 2015-11-30 | Yeda Res & Dev | Heterologous engineering of betalain pigments in plants |
| AU2017235543B2 (en) | 2016-03-16 | 2020-05-14 | Conagen, Inc. | Production of proteins in labyrinthulomycetes |
| EP3455351B1 (en) | 2016-05-12 | 2022-08-24 | DSM IP Assets B.V. | Method of increasing omega-3 polyunsaturated fatty acids production in microalgae |
| US10851395B2 (en) | 2016-06-10 | 2020-12-01 | MARA Renewables Corporation | Method of making lipids with improved cold flow properties |
| WO2018013821A1 (en) | 2016-07-13 | 2018-01-18 | Dsm Ip Assets B.V. | A crispr-cas system for an algal host cell |
| IL247752A0 (en) | 2016-09-11 | 2016-11-30 | Yeda Res & Dev | Compositions and methods for modulating gene expression for site-directed mutagenesis |
| US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
| WO2019078359A1 (ja) | 2017-10-19 | 2019-04-25 | 味の素株式会社 | ステロールの製造法 |
| WO2019173226A1 (en) * | 2018-03-05 | 2019-09-12 | Synthetic Genomics, Inc. | Organisms and methods for producing glycomolecules with low sulfation |
| EP3788164A4 (en) * | 2018-05-01 | 2022-01-26 | Conagen Inc. | RECOMBINANT ORGANISMS AND METHODS FOR PRODUCTION OF HIGH GLYCAN OCCUPANCY GLYCOMOLECULES |
| WO2020032261A1 (ja) * | 2018-08-10 | 2020-02-13 | 協和発酵バイオ株式会社 | エイコサペンタエン酸を生産する微生物及びエイコサペンタエン酸の製造法 |
| CN109777815B (zh) * | 2019-03-28 | 2021-10-29 | 昆明理工大学 | HMG-CoA合成酶基因RKHMGCS及其应用 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE545283A (enExample) | ||||
| LU35839A1 (enExample) | ||||
| US3223456A (en) * | 1963-11-14 | 1965-12-14 | Siemens Ag | Conveying apparatus for fine-granular material |
| US4381897A (en) * | 1980-10-06 | 1983-05-03 | Krupp Polysius Ag | Installation for transporting fine-grained material |
| US4626505A (en) * | 1984-02-24 | 1986-12-02 | E. I. Du Pont De Nemours And Company | Selectable markers for yeast transformation |
| US5605011A (en) * | 1986-08-26 | 1997-02-25 | E. I. Du Pont De Nemours And Company | Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase |
| IL83348A (en) * | 1986-08-26 | 1995-12-08 | Du Pont | Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase |
| US5130242A (en) * | 1988-09-07 | 1992-07-14 | Phycotech, Inc. | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
| US5340742A (en) | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
| US5426040A (en) | 1989-08-17 | 1995-06-20 | Northeastern University | Methods for producing improved strains of seaweed by fusion of spore-protoplasts, and resultant seaweeds and phycocolloids |
| IL100908A0 (en) | 1991-02-22 | 1992-11-15 | Salk Inst Biotech Ind | Invertase genes and their use |
| US5804408A (en) * | 1991-03-13 | 1998-09-08 | Yoshihide Hagiwara | Expression of human SOD in blue green algae |
| US5661017A (en) * | 1993-09-14 | 1997-08-26 | Dunahay; Terri Goodman | Method to transform algae, materials therefor, and products produced thereby |
| IL113375A (en) * | 1995-04-13 | 1997-09-30 | Fortress U & T Ltd | Internationally regulated system for one to one cryptographic communications with national sovereignty without key escrow |
| DK0821729T3 (da) * | 1995-04-20 | 2007-02-05 | Basf Ag | Strukturbaserede, udformede herbicidresistente produkter |
| US5853973A (en) * | 1995-04-20 | 1998-12-29 | American Cyanamid Company | Structure based designed herbicide resistant products |
| DE19529475A1 (de) | 1995-08-11 | 1997-02-13 | Marcus Weis | Siebkonstruktion zum Abtrennen des Faseranteils aus der Shredderleichtfraktion |
| WO1997020854A1 (en) | 1995-12-05 | 1997-06-12 | University Of Massachusetts | Recombinant gas vesicles and uses thereof |
| WO1997039106A1 (en) * | 1996-04-12 | 1997-10-23 | Martek Biosciences Corporation | Methods and tools for transformation of eukaryotic algae |
| US6194167B1 (en) * | 1997-02-18 | 2001-02-27 | Washington State University Research Foundation | ω-3 fatty acid desaturase |
| US5968809A (en) * | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| ES2125195B1 (es) | 1997-04-18 | 1999-10-01 | Antibioticos Sa | Procedimiento de inactivacion de genes que codifican para enzimas del catabolismo del fenilacetato, plasmidos que intervienen y cepas transformadas con los mismos. |
| US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| FR2791699B1 (fr) * | 1999-03-29 | 2004-10-29 | Meristem Therapeutics | Promoteurs chimeriques d'expression, cassettes d'expression, vecteurs, plantes et semences transgeniques les contenant, et methodes de leur obtention |
| KR20000075076A (ko) * | 1999-05-28 | 2000-12-15 | 최태진 | 형질전환된 미세조류를 이용하여 외래 단백질을 생산하는 방법 |
| US20060029604A1 (en) | 2000-06-28 | 2006-02-09 | Gerngross Tillman U | Immunoglobulins comprising predominantly a GlcNAc2Man3GlcNAc2 glycoform |
| US7029872B2 (en) | 2000-06-28 | 2006-04-18 | Glycofi, Inc | Methods for producing modified glycoproteins |
| US20060257399A1 (en) | 2000-06-28 | 2006-11-16 | Glycofi, Inc. | Immunoglobulins comprising predominantly a Man5GIcNAc2 glycoform |
| US7625756B2 (en) | 2000-06-28 | 2009-12-01 | GycoFi, Inc. | Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells |
| US7795002B2 (en) | 2000-06-28 | 2010-09-14 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| DK1911837T3 (da) | 2000-09-28 | 2011-08-29 | Bioriginal Food & Science Corp | FAD5-2 fedtsyredesaturasefamiliemedlem og anvendelser deraf |
| US6419425B1 (en) * | 2001-02-28 | 2002-07-16 | Neu Transf'air | Granular material distributing apparatus comprising at least two transfer vessels that operate in alternation |
| TWI377253B (en) * | 2001-04-16 | 2012-11-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7332299B2 (en) | 2003-02-20 | 2008-02-19 | Glycofi, Inc. | Endomannosidases in the modification of glycoproteins in eukaryotes |
| US7541038B2 (en) | 2003-06-05 | 2009-06-02 | Wyeth Holdings Corporation | Fusogenic, self-propagating blebs as immunogenic compositions |
| JP4796786B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
| JP4796787B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
| PT103331A (pt) | 2005-08-05 | 2007-02-28 | Fundacao Da Faculdade De Cienc | Expressão dum transportador activo de xilose em saccharomyces cerevisiae modificada geneticamente |
| WO2007106903A2 (en) | 2006-03-15 | 2007-09-20 | Martek Biosciences Corporation | Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems |
| US9023616B2 (en) | 2006-08-01 | 2015-05-05 | Dsm Nutritional Products Ag | Oil producing microbes and method of modification thereof |
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| EA019387B1 (ru) | 2007-09-12 | 2014-03-31 | Мартек Биосайнсиз Корпорейшн | Способ получения биологического масла и его использование в способе получения биодизеля |
| EP2090648A1 (en) | 2008-02-12 | 2009-08-19 | Institut Francais de Recherche pour l'Exploitation de la Mere(Ifremer) | Production of glycosylated polypeptides in microalgae |
| MX338039B (es) | 2008-04-09 | 2016-03-30 | Solazyme Inc | Modificacion quimica directa de biomasa bacteriana y aceites microbianos. |
| CN102906270B (zh) | 2009-12-28 | 2016-06-22 | Dsmip资产公司 | 在木糖上生长的重组破囊壶菌和其组合物、制备方法及用途 |
| EP2519625B1 (en) | 2009-12-28 | 2018-09-26 | DSM IP Assets B.V. | Recombinant thraustochytrids that grow on sucrose, and compositions, methods of making, and uses thereof |
| EA030095B1 (ru) | 2009-12-28 | 2018-06-29 | ДиЭсЭм АйПи АССЕТС Б.В. | Получение белка гемагглютинин-нейраминидазы в микроводорослях |
| CA2785971C (en) | 2009-12-28 | 2019-02-12 | Dsm Ip Assets B.V. | Production of heterologous polypeptides in microalgae, microalgal extracellular bodies, compositions, and methods of making and uses thereof |
-
2002
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- 2002-04-15 TW TW098130758A patent/TWI350854B/zh not_active IP Right Cessation
- 2002-04-15 TW TW091107634A patent/TWI324181B/zh not_active IP Right Cessation
- 2002-04-16 CA CA2443908A patent/CA2443908C/en not_active Expired - Fee Related
- 2002-04-16 EP EP10178886.7A patent/EP2325319B1/en not_active Expired - Lifetime
- 2002-04-16 EP EP10178911.3A patent/EP2314706B1/en not_active Expired - Lifetime
- 2002-04-16 ES ES10178911T patent/ES2698473T3/es not_active Expired - Lifetime
- 2002-04-16 US US10/124,807 patent/US7001772B2/en not_active Expired - Lifetime
- 2002-04-16 CN CN200910141898A patent/CN101760469A/zh active Pending
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- 2002-04-16 AU AU2002250592A patent/AU2002250592C1/en not_active Ceased
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- 2002-04-16 AT AT02719515T patent/ATE533844T1/de active
- 2002-04-16 WO PCT/US2002/012040 patent/WO2002083869A2/en not_active Ceased
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- 2002-04-16 JP JP2002582208A patent/JP4536324B2/ja not_active Expired - Fee Related
- 2002-04-16 CN CNB2006100842683A patent/CN100513564C/zh not_active Expired - Fee Related
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