JP2005503125A5 - - Google Patents
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- JP2005503125A5 JP2005503125A5 JP2002582208A JP2002582208A JP2005503125A5 JP 2005503125 A5 JP2005503125 A5 JP 2005503125A5 JP 2002582208 A JP2002582208 A JP 2002582208A JP 2002582208 A JP2002582208 A JP 2002582208A JP 2005503125 A5 JP2005503125 A5 JP 2005503125A5
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- JP
- Japan
- Prior art keywords
- nucleic acid
- acid sequence
- seq
- protein
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000007523 nucleic acids Chemical class 0.000 claims 53
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 35
- 108090000623 proteins and genes Proteins 0.000 claims 20
- 102000004169 proteins and genes Human genes 0.000 claims 18
- 125000003275 alpha amino acid group Chemical group 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 16
- 102000039446 nucleic acids Human genes 0.000 claims 16
- 108010000700 Acetolactate synthase Proteins 0.000 claims 12
- 238000000034 method Methods 0.000 claims 9
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 108010030975 Polyketide Synthases Proteins 0.000 claims 7
- 244000005700 microbiome Species 0.000 claims 7
- 102000004243 Tubulin Human genes 0.000 claims 5
- 108090000704 Tubulin Proteins 0.000 claims 5
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 4
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- BCIHMWNOJJYBSJ-UHFFFAOYSA-N 2-pyrimidin-2-yloxybenzoic acid Chemical compound OC(=O)C1=CC=CC=C1OC1=NC=CC=N1 BCIHMWNOJJYBSJ-UHFFFAOYSA-N 0.000 claims 3
- CAAMSDWKXXPUJR-UHFFFAOYSA-N 3,5-dihydro-4H-imidazol-4-one Chemical compound O=C1CNC=N1 CAAMSDWKXXPUJR-UHFFFAOYSA-N 0.000 claims 3
- 239000003112 inhibitor Substances 0.000 claims 3
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 claims 3
- 230000002103 transcriptional effect Effects 0.000 claims 3
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 claims 2
- 101710123462 Bleomycin resistance protein Proteins 0.000 claims 2
- 235000021294 Docosapentaenoic acid Nutrition 0.000 claims 2
- 102000009114 Fatty acid desaturases Human genes 0.000 claims 2
- 108010087894 Fatty acid desaturases Proteins 0.000 claims 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 2
- 235000021342 arachidonic acid Nutrition 0.000 claims 2
- 229940114079 arachidonic acid Drugs 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 2
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 2
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 2
- 230000006801 homologous recombination Effects 0.000 claims 2
- 238000002744 homologous recombination Methods 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 230000035945 sensitivity Effects 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 230000009466 transformation Effects 0.000 claims 2
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 claims 1
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 claims 1
- 241001467333 Thraustochytriaceae Species 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28411601P | 2001-04-16 | 2001-04-16 | |
| PCT/US2002/012040 WO2002083869A2 (en) | 2001-04-16 | 2002-04-16 | Product and process for transformation of thraustochytriales microorganisms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010019881A Division JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005503125A JP2005503125A (ja) | 2005-02-03 |
| JP2005503125A5 true JP2005503125A5 (enExample) | 2005-12-22 |
| JP4536324B2 JP4536324B2 (ja) | 2010-09-01 |
Family
ID=23088908
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582208A Expired - Fee Related JP4536324B2 (ja) | 2001-04-16 | 2002-04-16 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2010019881A Expired - Lifetime JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2012215905A Withdrawn JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2015253726A Expired - Fee Related JP6211577B2 (ja) | 2001-04-16 | 2015-12-25 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010019881A Expired - Lifetime JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2012215905A Withdrawn JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2015253726A Expired - Fee Related JP6211577B2 (ja) | 2001-04-16 | 2015-12-25 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7001772B2 (enExample) |
| EP (3) | EP2325319B1 (enExample) |
| JP (4) | JP4536324B2 (enExample) |
| CN (3) | CN1556850B (enExample) |
| AT (1) | ATE533844T1 (enExample) |
| AU (1) | AU2002250592C1 (enExample) |
| CA (1) | CA2443908C (enExample) |
| ES (3) | ES2688953T3 (enExample) |
| TW (3) | TWI324181B (enExample) |
| WO (1) | WO2002083869A2 (enExample) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US8003772B2 (en) * | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| TWI324181B (en) * | 2001-04-16 | 2010-05-01 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7211656B2 (en) * | 2002-01-30 | 2007-05-01 | Abbott Laboratories | Desaturase genes, enzymes encoded thereby, and uses thereof |
| ATE354645T1 (de) * | 2002-12-20 | 2007-03-15 | Chromagenics Bv | Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können |
| US7208590B2 (en) * | 2003-07-15 | 2007-04-24 | Abbott Laboratories | Genes involved in polyketide synthase pathways and uses thereof |
| CA3056110C (en) | 2004-04-22 | 2020-07-14 | Surinder Pal Singh | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| DK1756280T3 (en) | 2004-04-22 | 2015-02-02 | Commw Scient Ind Res Org | SYNTHESIS OF CHAIN, polyunsaturated fatty acids BY RECOMBINANT CELLS |
| KR101271884B1 (ko) * | 2004-11-08 | 2013-06-05 | 크로마제닉스 비.브이. | 고수준으로 단백질을 발현하는 숙주세포의 선택 |
| US8999667B2 (en) * | 2004-11-08 | 2015-04-07 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| ES2384391T3 (es) * | 2004-11-08 | 2012-07-04 | Chromagenics B.V. | Selección de células hospedantes que expresan proteína a altos niveles |
| US20060195935A1 (en) | 2004-11-08 | 2006-08-31 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20100136616A1 (en) * | 2004-11-08 | 2010-06-03 | Chromagenics B.V. | Selection of Host Cells Expressing Protein at High Levels |
| JP4796786B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
| JP4796787B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
| ES2626018T3 (es) | 2005-06-07 | 2017-07-21 | Dsm Nutritional Products Ag | Microorganismos eucariotas para la producción de lípidos y antioxidantes |
| DK1951866T3 (da) | 2005-11-23 | 2014-10-27 | Du Pont | Delta-9-elongaser og anvendelse heraf til fremstilling af flerumættede fedtsyrer |
| EP1818411A1 (en) * | 2006-02-13 | 2007-08-15 | Lonza AG | Process for the preparation of optically active chiral amines |
| KR101524398B1 (ko) | 2006-03-15 | 2015-06-04 | 디에스엠 아이피 어셋츠 비.브이. | Ｐｕｆａ 폴리케티드 신타제 시스템을 이용한 이종 생물체내 다불포화 지방산의 제조 |
| TW200806184A (en) * | 2006-04-11 | 2008-02-01 | Martek Biosciences Corp | Food products comprising long chain polyunsaturated fatty acids and methods for preparing the same |
| CA2655044C (en) | 2006-06-22 | 2014-05-27 | Martek Biosciences Corporation | Encapsulated labile compound compositions and methods of making the same |
| CN101981201A (zh) * | 2006-08-01 | 2011-02-23 | 加拿大海洋营养食品有限公司 | 产油微生物及改良这些微生物的方法 |
| WO2008027991A2 (en) | 2006-08-29 | 2008-03-06 | Martek Biosciences Corporation | USE OF DPA(n-6) OILS IN INFANT FORMULA |
| CN101578363A (zh) | 2006-08-29 | 2009-11-11 | 联邦科学技术研究组织 | 脂肪酸的合成 |
| KR100860111B1 (ko) * | 2006-10-02 | 2008-09-25 | 인제대학교 산학협력단 | 신규 미생물 트라우스토카이트리움 에스피.케이제이에스-1, 바실러스 폴리퍼멘티쿠스 케이제이에스-2 및 이들과 바실러스 리케니포르미스를 포함하고 있는 사료첨가제 및 사료 |
| US20110016581A1 (en) | 2006-10-23 | 2011-01-20 | E.I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
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| US7794701B2 (en) | 2007-04-16 | 2010-09-14 | E.I. Du Pont De Nemours And Company | Δ-9 elongases and their use in making polyunsaturated fatty acids |
| US8957280B2 (en) | 2007-05-03 | 2015-02-17 | E. I. Du Pont De Nemours And Company | Delta-5 desaturases and their use in making polyunsaturated fatty acids |
| JP2010532418A (ja) * | 2007-06-29 | 2010-10-07 | マーテック バイオサイエンシーズ コーポレーション | 多価不飽和脂肪酸のエステルの製造方法および精製方法 |
| CN101874117A (zh) | 2007-09-12 | 2010-10-27 | 马太克生物科学公司 | 生物油及其制备与应用 |
| US20110076379A1 (en) * | 2008-06-13 | 2011-03-31 | Means Michael M | High omega saturated fat free meat products |
| NO2358882T3 (enExample) | 2008-11-18 | 2017-12-23 | ||
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| CN104263729B (zh) * | 2009-03-16 | 2020-09-15 | 帝斯曼知识产权资产有限公司 | 在网粘菌门微生物中产生蛋白质 |
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| ES2717102T3 (es) | 2009-03-19 | 2019-06-19 | Dsm Ip Assets Bv | Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos |
| CN102459627B (zh) | 2009-06-16 | 2015-07-29 | 纳幕尔杜邦公司 | 通过酰基-辅酶A溶血磷脂酰基转移酶的表达对长链ω-3和ω-6多不饱和脂肪酸的生物合成的改善 |
| CA3121944A1 (en) * | 2009-09-24 | 2011-03-31 | Kyushu University, National University Corporation | Method for transforming stramenopiles |
| CN103068965A (zh) * | 2009-12-28 | 2013-04-24 | Dsmip资产公司 | 在蔗糖上生长的重组破囊壶菌和其组合物、制备方法及用途 |
| US10633667B2 (en) * | 2009-12-28 | 2020-04-28 | Boehringer Ingelheim Animal Health USA Inc. | Recombinant NDV antigen and uses thereof |
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| US8950312B2 (en) * | 2011-08-17 | 2015-02-10 | Lwrc International Llc | Bolt carrier and bolt for gas operated firearms |
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| US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
| EP3699282A4 (en) | 2017-10-19 | 2021-09-29 | Ajinomoto Co., Inc. | STEROL PRODUCTION PROCESS |
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- 2002-04-16 AT AT02719515T patent/ATE533844T1/de active
- 2002-04-16 EP EP10178886.7A patent/EP2325319B1/en not_active Expired - Lifetime
- 2002-04-16 ES ES10178886.7T patent/ES2688953T3/es not_active Expired - Lifetime
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- 2002-04-16 WO PCT/US2002/012040 patent/WO2002083869A2/en not_active Ceased
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