JP2008524984A5 - - Google Patents
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- Publication number
- JP2008524984A5 JP2008524984A5 JP2007540145A JP2007540145A JP2008524984A5 JP 2008524984 A5 JP2008524984 A5 JP 2008524984A5 JP 2007540145 A JP2007540145 A JP 2007540145A JP 2007540145 A JP2007540145 A JP 2007540145A JP 2008524984 A5 JP2008524984 A5 JP 2008524984A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- diacylglycerol acyltransferase
- triacylglycerol
- nucleic acid
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101000785223 Crocosmia x crocosmiiflora Myricetin 3-O-glucosyl 1,2-rhamnoside 6'-O-caffeoyltransferase AT1 Proteins 0.000 claims 22
- 150000001982 diacylglycerols Chemical class 0.000 claims 22
- 108020004707 nucleic acids Proteins 0.000 claims 19
- 102000039446 nucleic acids Human genes 0.000 claims 19
- 150000007523 nucleic acids Chemical class 0.000 claims 19
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 claims 18
- 125000003275 alpha amino acid group Chemical group 0.000 claims 17
- 108090000623 proteins and genes Proteins 0.000 claims 17
- 108090000790 Enzymes Proteins 0.000 claims 15
- 102000004190 Enzymes Human genes 0.000 claims 15
- 238000000034 method Methods 0.000 claims 14
- 229920001184 polypeptide Polymers 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 13
- 239000002773 nucleotide Substances 0.000 claims 9
- 125000003729 nucleotide group Chemical group 0.000 claims 9
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 9
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 9
- 235000020665 omega-6 fatty acid Nutrition 0.000 claims 9
- 229940033080 omega-6 fatty acid Drugs 0.000 claims 9
- 235000014113 dietary fatty acids Nutrition 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 6
- 229930195729 fatty acid Natural products 0.000 claims 6
- 239000000194 fatty acid Substances 0.000 claims 6
- 150000004665 fatty acids Chemical class 0.000 claims 6
- 230000000295 complement effect Effects 0.000 claims 5
- 230000001105 regulatory effect Effects 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 3
- 230000006696 biosynthetic metabolic pathway Effects 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 230000002538 fungal effect Effects 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 238000005406 washing Methods 0.000 claims 2
- 108700016155 Acyl transferases Proteins 0.000 claims 1
- 102000057234 Acyl transferases Human genes 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- 239000013599 cloning vector Substances 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- 230000002194 synthesizing effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62481204P | 2004-11-04 | 2004-11-04 | |
| US11/024,544 US7273746B2 (en) | 2004-11-04 | 2004-12-29 | Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| PCT/US2005/040345 WO2006052914A2 (en) | 2004-11-04 | 2005-11-03 | Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008524984A JP2008524984A (ja) | 2008-07-17 |
| JP2008524984A5 true JP2008524984A5 (enExample) | 2008-12-11 |
Family
ID=36262489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007540145A Pending JP2008524984A (ja) | 2004-11-04 | 2005-11-03 | 油性生物体中の多価不飽和脂肪酸および含油量変更のためのジアシルグリセロールアシルトランスフェラーゼ |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US7273746B2 (enExample) |
| EP (1) | EP1807525A4 (enExample) |
| JP (1) | JP2008524984A (enExample) |
| CA (1) | CA2585404A1 (enExample) |
| WO (2) | WO2006052912A2 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1756280T3 (pl) | 2004-04-22 | 2015-04-30 | Commw Scient Ind Res Org | Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych |
| ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| AU2005250074B2 (en) * | 2004-06-04 | 2011-04-14 | Fluxome Sciences A/S | Metabolically engineered cells for the production of polyunsaturated fatty acids |
| US7550286B2 (en) | 2004-11-04 | 2009-06-23 | E. I. Du Pont De Nemours And Company | Docosahexaenoic acid producing strains of Yarrowia lipolytica |
| BRPI0716075A2 (pt) | 2006-08-29 | 2013-08-06 | Commw Scient Ind Res Org | sÍntese de Ácidos graxos |
| US7709239B2 (en) * | 2006-12-07 | 2010-05-04 | E.I. Du Pont De Nemours And Company | Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids |
| EP2730656A1 (en) | 2007-05-24 | 2014-05-14 | E. I. du Pont de Nemours and Company | Soybean meal from beans having DGAT genes from yarrowia lipolytica for increased seed storage lipid production and altered fatty acid profiles in soybean |
| CA2701130A1 (en) * | 2007-10-03 | 2009-04-09 | E.I. Du Pont De Nemours And Company | Peroxisome biogenesis factor protein (pex) disruptions for altering the content of polyunsaturated fatty acids and the total lipid content in oleaginous eukaryotic organisms |
| EP2620501A3 (en) * | 2008-05-23 | 2013-10-02 | E. I. du Pont de Nemours and Company | DGAT genes from oleaginous organisms for increased seed storage lipid production and altered fatty acid profiles in oilseed plants |
| EP2282629A1 (en) | 2008-05-23 | 2011-02-16 | E. I. du Pont de Nemours and Company | Dgat genes from yarrowia lipolytica combined with plastidic phosphoglucomutase down regulation for increased seed storage lipid production and altered fatty acid profiles in oilseed plants |
| EP2324120B1 (en) | 2008-08-29 | 2016-01-27 | E. I. du Pont de Nemours and Company | Manipulation of snf1 protein kinase activity for altered oil content in oleaginous organisms |
| CA3015426C (en) | 2008-11-18 | 2020-01-14 | Commonwealth Scientific And Industrial Research Organisation | Recombinant cells comprising exogenous .delta.5 and .delta.6 desaturases, .delta.5 and .delta.6 elongases, and .delta.4 desaturases |
| US8431772B1 (en) | 2008-11-19 | 2013-04-30 | University Of Kentucky Research Foundation | Diacylglycerol acyltransferase sequences and related methods |
| US8993840B2 (en) | 2009-11-23 | 2015-03-31 | E I du Pont de Nemours and Compay | Sucrose transporter genes for increasing plant seed lipids |
| CN102844431B (zh) | 2009-12-21 | 2014-10-08 | 三得利控股株式会社 | 二酰甘油酰基转移酶基因及其用途 |
| EP3521408B1 (en) | 2010-11-03 | 2021-12-22 | Corbion Biotech, Inc. | Genetically-engineered chlorella or prototheca microbe and oil produced therefrom |
| US8969049B2 (en) | 2011-03-31 | 2015-03-03 | E I Du Pont De Nemours And Company | Yarrowia diacylglycerol acyltransferase promoter regions for gene expression in yeast |
| EP2714724A1 (en) | 2011-05-26 | 2014-04-09 | E. I. Du Pont de Nemours and Company | Expression of caleosin in recombinant oleaginous microorganisms to increase oil content therein |
| EP3388516A1 (en) * | 2011-10-19 | 2018-10-17 | Massachusetts Institute Of Technology | Engineered microbes and methods for microbial oil production |
| WO2013096562A1 (en) | 2011-12-22 | 2013-06-27 | E. I. Du Pont De Nemours And Company | Use of the soybean sucrose synthase promoter to increase plant seed lipid content |
| HUE033766T2 (en) | 2012-06-15 | 2018-01-29 | Commw Scient Ind Res Org | Production of long chain polyunsaturated fatty acids in plant cells |
| BR112015002940A2 (pt) | 2012-08-10 | 2018-04-24 | Opx Biotechnologies Inc | microorganismos e métodos para a produção de ácidos graxos e produtos derivados de ácidos graxos. |
| WO2014062163A1 (en) | 2012-10-16 | 2014-04-24 | Exxonmobil Research And Engineering Company | Dgat genes and methods of use for triglyceride production in recombinant microorganisms |
| BR112015009303A2 (pt) * | 2012-10-30 | 2017-08-22 | Agresearch Ltd | Novos polipeptídeos, polinucleotídeos de aciltransferase, e métodos de uso |
| PL2914726T3 (pl) | 2012-10-30 | 2019-06-28 | Agresearch Limited | Udoskonalone polinukleotydy acylotransferazy, polipeptydy i sposoby stosowania |
| CN105473718A (zh) | 2012-10-30 | 2016-04-06 | 农业研究有限公司 | 增强的酰基转移酶的多核苷酸、多肽、及其使用方法 |
| EP2929040A4 (en) | 2012-12-06 | 2016-11-09 | Exxonmobil Res & Eng Co | DGAT GENES WITH PLECKSTRIN HOMOLOGY DOMAINS AND USE IN RECOMBINANT MICROORGANISMS |
| CN109576241A (zh) | 2012-12-21 | 2019-04-05 | 新西兰植物和食品研究院有限公司 | 基因表达的调控 |
| US9447438B2 (en) | 2013-03-15 | 2016-09-20 | Cargill, Incorporated | Acetyl-coA carboxylases |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| WO2015010103A2 (en) | 2013-07-19 | 2015-01-22 | Opx Biotechnologies, Inc. | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| EA037817B1 (ru) | 2013-12-18 | 2021-05-25 | Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн | Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты |
| AU2015218647B2 (en) | 2014-02-24 | 2021-10-21 | Ginkgo Bioworks, Inc. | Diacylglycerol acyl transferase (DGA1) polynucleotides, and methods of increasing yeast cell lipid production by overexpression of heterologous DGA1 |
| AR100159A1 (es) | 2014-04-22 | 2016-09-14 | Du Pont | Genes de anhidrasa carbónica plastídica para el incremento de aceite en semillas con expresión incrementada de dgat |
| CA2953008C (en) | 2014-06-27 | 2024-03-19 | Nuseed Pty Ltd | Lipid comprising docosapentaenoic acid |
| EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
| WO2018047657A1 (ja) * | 2016-09-07 | 2018-03-15 | 花王株式会社 | 脂質の製造方法 |
| WO2018140782A1 (en) | 2017-01-27 | 2018-08-02 | Marks Michael David | Plants having increased oil quality |
| CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
| US11337391B2 (en) | 2017-08-18 | 2022-05-24 | Regents Of The University Of Minnesota | Early flowering plants |
| US11707029B2 (en) | 2017-08-18 | 2023-07-25 | Regents Of The University Of Minnesota | Oilseed plants having reduced pod shatter |
| US12221612B2 (en) | 2018-02-12 | 2025-02-11 | Regents Of The University Of Minnesota | Plants having increased oil quality |
| CN109837256B (zh) * | 2019-03-21 | 2020-12-01 | 江南大学 | 一种二酰甘油酰基转移酶1及其在生产甘油三酯中的应用 |
| US11408008B2 (en) * | 2019-03-28 | 2022-08-09 | Regents Of The University Of Minnesota | Plants having increased oil quality |
| CN114517164A (zh) * | 2020-11-19 | 2022-05-20 | 中国科学院青岛生物能源与过程研究所 | 一种脂肪酸延长酶基因在酵母合成神经酸中的应用 |
| MX2023010280A (es) * | 2021-03-03 | 2023-09-11 | Nourish Ingredients Pty Ltd | Produccion de fosfolipidos en microbios y usos de los mismos. |
| CN116396875A (zh) * | 2022-12-20 | 2023-07-07 | 华东理工大学 | 一种解脂耶氏酵母基因工程菌及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4792523A (en) | 1984-08-31 | 1988-12-20 | Cetus Corporation | 3'Expression enhancing fragments and method |
| US6432684B1 (en) * | 1997-04-11 | 2002-08-13 | Abbott Laboratories | Human desaturase gene and uses thereof |
| US20030167483A1 (en) * | 1998-06-24 | 2003-09-04 | Farese Robert V. | Diacylglycerol O-acyltransferase |
| US6344548B1 (en) * | 1998-06-24 | 2002-02-05 | The Regents Of The University Of California | Diacylglycerol o-acyltransferase |
| US6100077A (en) * | 1998-10-01 | 2000-08-08 | The Trustees Of Columbia University In The City Of New York | Isolation of a gene encoding diacylglycerol acyltransferase |
| CA2851896C (en) * | 1998-12-02 | 2016-05-17 | Karlene H. Butler | Plant diacylglycerol acyltransferases |
| HUP0200480A3 (en) | 1999-04-01 | 2009-08-28 | Basf Plant Science Gmbh | Enzymes of the biosynthetic pathway for the production of triacylglycerol and recombinant dna molecules encoding these enzymes |
| DE19950921A1 (de) * | 1999-10-21 | 2001-04-26 | Basf Ag | The N-terminal beta-barrel Structur der Lipidkörperlipoxygenase vermittelt ihre Bindung an Liposomen und Lipidkörper |
| US6552250B1 (en) * | 2000-06-14 | 2003-04-22 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food | Diacylglycerol O-acyltransferase |
| SE0201581D0 (sv) * | 2002-05-29 | 2002-05-29 | Scandinavian Biotechnology Res | New improved acyltransferase |
| CA2492205A1 (en) | 2002-07-31 | 2004-02-05 | Monsanto Technology, Llc | Diacylglycerol acyltransferase nucleic acid sequences and associated products |
| EP2431048B1 (en) * | 2002-10-08 | 2015-03-11 | Danisco US Inc. | Phenolic binding peptides |
| US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| US7267976B2 (en) | 2003-07-02 | 2007-09-11 | E.I. Du Pont De Nemours And Company | Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts |
-
2004
- 2004-12-29 US US11/024,544 patent/US7273746B2/en not_active Expired - Fee Related
-
2005
- 2005-11-03 CA CA002585404A patent/CA2585404A1/en not_active Abandoned
- 2005-11-03 WO PCT/US2005/040341 patent/WO2006052912A2/en not_active Ceased
- 2005-11-03 EP EP05816761A patent/EP1807525A4/en not_active Withdrawn
- 2005-11-03 WO PCT/US2005/040345 patent/WO2006052914A2/en not_active Ceased
- 2005-11-03 JP JP2007540145A patent/JP2008524984A/ja active Pending
-
2007
- 2007-07-30 US US11/830,023 patent/US20080020415A1/en not_active Abandoned
-
2008
- 2008-12-18 US US12/338,536 patent/US8685681B2/en not_active Expired - Fee Related
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