JP2009517019A5 - - Google Patents
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- JP2009517019A5 JP2009517019A5 JP2008542346A JP2008542346A JP2009517019A5 JP 2009517019 A5 JP2009517019 A5 JP 2009517019A5 JP 2008542346 A JP2008542346 A JP 2008542346A JP 2008542346 A JP2008542346 A JP 2008542346A JP 2009517019 A5 JP2009517019 A5 JP 2009517019A5
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- Prior art keywords
- seq
- sequence
- polypeptide
- acid sequence
- amino acid
- Prior art date
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- 239000002773 nucleotide Substances 0.000 claims 12
- 125000003729 nucleotide group Chemical group 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 9
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 150000007523 nucleic acids Chemical group 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 6
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 4
- 235000014113 dietary fatty acids Nutrition 0.000 claims 4
- 229930195729 fatty acid Natural products 0.000 claims 4
- 239000000194 fatty acid Substances 0.000 claims 4
- 150000004665 fatty acids Chemical class 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 229960004488 linolenic acid Drugs 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- XSXIVVZCUAHUJO-AVQMFFATSA-N (11e,14e)-icosa-11,14-dienoic acid Chemical compound CCCCC\C=C\C\C=C\CCCCCCCCCC(O)=O XSXIVVZCUAHUJO-AVQMFFATSA-N 0.000 claims 1
- BBWMTEYXFFWPIF-CJBMEHDJSA-N (2e,4e,6e)-icosa-2,4,6-trienoic acid Chemical compound CCCCCCCCCCCCC\C=C\C=C\C=C\C(O)=O BBWMTEYXFFWPIF-CJBMEHDJSA-N 0.000 claims 1
- 235000021297 Eicosadienoic acid Nutrition 0.000 claims 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims 1
- 241000970807 Thermoanaerobacterales Species 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 235000020778 linoleic acid Nutrition 0.000 claims 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73998905P | 2005-11-23 | 2005-11-23 | |
| US60/739,989 | 2005-11-23 | ||
| PCT/US2006/044480 WO2007061742A1 (en) | 2005-11-23 | 2006-11-16 | Delta-9 elongases and their use in making polyunsaturated fatty acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009517019A JP2009517019A (ja) | 2009-04-30 |
| JP2009517019A5 true JP2009517019A5 (enExample) | 2010-01-07 |
| JP5123861B2 JP5123861B2 (ja) | 2013-01-23 |
Family
ID=37836626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008542346A Expired - Fee Related JP5123861B2 (ja) | 2005-11-23 | 2006-11-16 | Δ９エロンガーゼおよびそれらの多価不飽和脂肪酸製造における使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US20070118929A1 (enExample) |
| EP (2) | EP1957641A2 (enExample) |
| JP (1) | JP5123861B2 (enExample) |
| KR (1) | KR20080071190A (enExample) |
| CN (1) | CN101365788B (enExample) |
| AU (2) | AU2006318738B2 (enExample) |
| BR (1) | BRPI0620552A2 (enExample) |
| CA (2) | CA2625855C (enExample) |
| DK (1) | DK1951866T3 (enExample) |
| NO (1) | NO20082466L (enExample) |
| WO (2) | WO2007061742A1 (enExample) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1756280T3 (pl) | 2004-04-22 | 2015-04-30 | Commw Scient Ind Res Org | Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych |
| ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| GB0603160D0 (en) * | 2006-02-16 | 2006-03-29 | Rothamsted Res Ltd | Nucleic acid |
| BRPI0716075A2 (pt) | 2006-08-29 | 2013-08-06 | Commw Scient Ind Res Org | sÍntese de Ácidos graxos |
| CA2663768A1 (en) | 2006-10-23 | 2008-05-29 | E. I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
| US8916361B2 (en) | 2006-11-17 | 2014-12-23 | Abbott Laboratories | Elongase gene and uses thereof |
| US20080125487A1 (en) * | 2006-11-17 | 2008-05-29 | Tapas Das | Elongase gene and uses thereof |
| US7709239B2 (en) * | 2006-12-07 | 2010-05-04 | E.I. Du Pont De Nemours And Company | Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids |
| EP2121934A2 (en) | 2007-02-12 | 2009-11-25 | E. I. Du Pont de Nemours and Company | Production of arachidonic acid in oilseed plants |
| DK2129777T3 (en) | 2007-04-03 | 2016-01-25 | Du Pont | MULTIZYMER AND USE THEREOF FOR THE PRODUCTION OF polyunsaturated fatty acids |
| US8188338B2 (en) | 2007-04-10 | 2012-05-29 | E. I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
| US8119860B2 (en) | 2007-04-16 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| WO2009016208A2 (de) | 2007-07-31 | 2009-02-05 | Basf Plant Science Gmbh | Elongasen und verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen |
| US8323935B2 (en) * | 2007-10-03 | 2012-12-04 | E I Du Pont De Nemours And Company | Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production |
| CA2701130A1 (en) * | 2007-10-03 | 2009-04-09 | E.I. Du Pont De Nemours And Company | Peroxisome biogenesis factor protein (pex) disruptions for altering the content of polyunsaturated fatty acids and the total lipid content in oleaginous eukaryotic organisms |
| US8168858B2 (en) | 2008-06-20 | 2012-05-01 | E. I. Du Pont De Nemours And Company | Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids |
| CA3015426C (en) | 2008-11-18 | 2020-01-14 | Commonwealth Scientific And Industrial Research Organisation | Recombinant cells comprising exogenous .delta.5 and .delta.6 desaturases, .delta.5 and .delta.6 elongases, and .delta.4 desaturases |
| CA2744716C (en) | 2008-12-18 | 2017-05-23 | E.I. Du Pont De Nemours And Company | Reducing byproduction of malonates in a fermentation process |
| EP2414522B1 (en) | 2009-04-01 | 2014-08-20 | E. I. du Pont de Nemours and Company | Use of a seed specific promoter to drive odp1 expression in cruciferous oilseed plants to increase oil content while maintaining normal germination |
| US9925162B2 (en) | 2009-04-09 | 2018-03-27 | The Regents Of The University Of Colorado | Methods and compositions for inducing physiological hypertrophy |
| WO2010147907A1 (en) | 2009-06-16 | 2010-12-23 | E. I. Du Pont De Nemours And Company | High eicosapentaenoic acid oils from improved optimized strains of yarrowia lipolytica |
| CN102803289B (zh) | 2009-06-16 | 2015-07-22 | 纳幕尔杜邦公司 | 用于高水平生产二十碳五烯酸的改善的优化的解脂耶氏酵母菌株 |
| BRPI1009690A2 (pt) | 2009-06-16 | 2015-08-25 | Du Pont | "célula hospedeira microbiana oleaginosa, óleo, método de elaboração de um óleo, método de aumento da eficiência de conversão de alongamento de c18 para c20 em uma célula hospedeira recombinante microbiana oleaginosa e método de aumento da eficiência de conversão de dessaturação (delta) 4 em uma célula hospedeira recombinante microbiana oleaginosa produtora de ácidos graxos póli-insaturados de cadeia longa" |
| CA2764073A1 (en) | 2009-06-30 | 2011-01-20 | E. I. Du Pont De Nemours And Company | Plant seeds with altered storage compound levels, related constructs and methods involving genes encoding cytosolic pyrophosphatase |
| US8188335B2 (en) * | 2009-07-17 | 2012-05-29 | Abbott Laboratories | Δ9-elongase for production of polyunsaturated fatty acid-enriched oils |
| AR078829A1 (es) | 2009-10-30 | 2011-12-07 | Du Pont | Plantas y semillas con niveles alterados de compuesto de almacenamiento, construcciones relacionadas y metodos relacionados con genes que codifican proteinas similares a las aldolasas bacterianas de la clase ii del acido 2,4- dihidroxi-hept-2-eno-1,7-dioico |
| BR112012015641A2 (pt) * | 2009-12-24 | 2015-11-24 | Du Pont | "polinucleotídeo isolado, construtor de dna recombinante, célula hospedeira, método para produzir uma planta transformada, para aumentar o teor de pelo menos um um ácido graxo, para aumentar pelo menos uma eficiencia de conversão, semente transgênica, plantas, óleos, alimento humano ou de animal e plantas de progênie" |
| WO2011087981A2 (en) | 2010-01-15 | 2011-07-21 | E. I. Du Pont De Nemours And Company | Clinical benefits of eicosapentaenoic acid in humans |
| EP2860254A1 (en) | 2010-03-03 | 2015-04-15 | E. I. du Pont de Nemours and Company | Plant seeds with altered storage compound levels, related constructs and methods involving genes encoding oxidoreductase motif polypeptides |
| CN103282474A (zh) | 2010-04-22 | 2013-09-04 | 纳幕尔杜邦公司 | 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法 |
| BR112012033668A2 (pt) | 2010-07-01 | 2017-06-13 | Du Pont | planta e semente transgênica, método para a produção de um planta transgênica, produto e/ou subproduto obtido a partir da semente transgênica, polinucleotídeo isolado e planta ou semente compreendendo uma cosntrução de dna recombinante |
| US20120040076A1 (en) | 2010-08-11 | 2012-02-16 | E. I. Du Pont De Nemours And Company | Aquaculture feed compositions |
| WO2012021686A1 (en) | 2010-08-11 | 2012-02-16 | E. I. Du Pont De Nemours And Company | Improved aquaculture meat products |
| EP2603094A1 (en) | 2010-08-11 | 2013-06-19 | E.I. Du Pont De Nemours And Company | A sustainable aquaculture feeding strategy |
| AU2011293189B2 (en) | 2010-08-26 | 2017-02-16 | E. I. Du Pont De Nemours And Company | Mutant HPGG motif and HDASH motif delta-5 desaturases and their use in making polyunsaturated fatty acids |
| US8703473B2 (en) * | 2010-08-26 | 2014-04-22 | E I Du Pont De Nemours And Company | Recombinant microbial host cells for high eicosapentaenoic acid production |
| WO2012027676A1 (en) * | 2010-08-26 | 2012-03-01 | E. I. Du Pont De Nemours And Company | Mutant delta-9 elongases and their use in making polyunsaturated fatty acids |
| BR112013016769A2 (pt) | 2010-12-30 | 2016-10-11 | Du Pont | yarrowia lipolytica transformada e método para produzir pelo menos um produto não nativo de interesse |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| JP6061866B2 (ja) | 2011-02-11 | 2017-01-18 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ | 微生物バイオマスから脂質含有組成物を得る方法 |
| US8969049B2 (en) | 2011-03-31 | 2015-03-03 | E I Du Pont De Nemours And Company | Yarrowia diacylglycerol acyltransferase promoter regions for gene expression in yeast |
| EP2694665A1 (en) | 2011-04-01 | 2014-02-12 | E. I. Du Pont de Nemours and Company | Yarrowia esterase/lipase promoter regions for gene expression in yeast |
| US20120247066A1 (en) | 2011-04-01 | 2012-10-04 | Ice House America, Llc | Ice bagging apparatus and methods |
| WO2012138613A1 (en) | 2011-04-05 | 2012-10-11 | E. I. Du Pont De Nemours And Company | Yarrowia n-alkane-hydroxylating cytochrome p450 promoter regions for gene expression in yeast |
| EP2702148A1 (en) | 2011-04-07 | 2014-03-05 | E.I. Du Pont De Nemours And Company | Yarrowia peroxisomal 2,4-dienoyl-coa reductase promoter regions for gene expression in yeast |
| WO2013096562A1 (en) | 2011-12-22 | 2013-06-27 | E. I. Du Pont De Nemours And Company | Use of the soybean sucrose synthase promoter to increase plant seed lipid content |
| WO2013112523A2 (en) | 2012-01-23 | 2013-08-01 | E. I. Du Pont De Nemours And Company | Down-regulation of gene expression using artificial micrornas for silencing fatty acid biosynthestic genes |
| HUE033766T2 (en) | 2012-06-15 | 2018-01-29 | Commw Scient Ind Res Org | Production of long chain polyunsaturated fatty acids in plant cells |
| CA2892516A1 (en) | 2012-12-21 | 2014-06-26 | E. I. Du Pont De Nemours And Company | Down-regulation of a polynucleotide encoding a sou2 sorbitol utilization protein to modify lipid production in microbial cells |
| KR20230119731A (ko) | 2013-06-12 | 2023-08-16 | 솔라베스트 바이오에너지 인코퍼레이티드 | 조류 세포 배양물 및 바이오매스, 지질 화합물 및 조성물,그리고 관련 산물을 생산하는 방법 |
| US20160272997A1 (en) | 2013-10-25 | 2016-09-22 | Pioneer Hi-Bred International, Inc. | Stem canker tolerant soybeans and methods of use |
| EA037817B1 (ru) | 2013-12-18 | 2021-05-25 | Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн | Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты |
| CA2953008C (en) | 2014-06-27 | 2024-03-19 | Nuseed Pty Ltd | Lipid comprising docosapentaenoic acid |
| FR3028527A1 (fr) * | 2014-11-13 | 2016-05-20 | Pivert | Identification de facteurs de transcription de yarrowia lipolytica |
| ES2608968B1 (es) * | 2015-09-08 | 2018-03-01 | Neol Biosolutions, S.A. | Producción de aceites microbianos con alto contenido en ácidos grasos de cadena muy larga |
| CN106874709B (zh) * | 2015-12-12 | 2019-03-01 | 北京大学 | 测序结果中序列数据错误的检测和校正方法 |
| CN116426621A (zh) | 2015-11-19 | 2023-07-14 | 赛纳生物科技(北京)有限公司 | 一种校正测序信息错误的方法 |
| US11096344B2 (en) | 2016-02-05 | 2021-08-24 | Pioneer Hi-Bred International, Inc. | Genetic loci associated with brown stem rot resistance in soybean and methods of use |
| FR3053052B1 (fr) * | 2016-06-28 | 2021-02-12 | Fermentalg | Microalgue modifiee pour une production enrichie en tag |
| US10513718B2 (en) * | 2017-06-06 | 2019-12-24 | City University Of Hong Kong | Method of producing polyunsaturated fatty acid |
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| US7125672B2 (en) * | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
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| PT2172536T (pt) | 2003-08-01 | 2016-08-17 | Basf Plant Science Gmbh | Processo para a produção de ácidos gordos poli-insaturados em organismos transgénicos |
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| EP4219670A3 (de) | 2004-02-27 | 2023-08-09 | BASF Plant Science GmbH | Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen pflanzen |
| PL1756280T3 (pl) | 2004-04-22 | 2015-04-30 | Commw Scient Ind Res Org | Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych |
| US7550651B2 (en) | 2004-06-25 | 2009-06-23 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| US7550286B2 (en) * | 2004-11-04 | 2009-06-23 | E. I. Du Pont De Nemours And Company | Docosahexaenoic acid producing strains of Yarrowia lipolytica |
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2006
- 2006-11-16 WO PCT/US2006/044480 patent/WO2007061742A1/en not_active Ceased
- 2006-11-16 WO PCT/US2006/044676 patent/WO2007061845A2/en not_active Ceased
- 2006-11-16 CN CN200680051550XA patent/CN101365788B/zh not_active Expired - Fee Related
- 2006-11-16 JP JP2008542346A patent/JP5123861B2/ja not_active Expired - Fee Related
- 2006-11-16 US US11/601,563 patent/US20070118929A1/en not_active Abandoned
- 2006-11-16 AU AU2006318738A patent/AU2006318738B2/en not_active Ceased
- 2006-11-16 DK DK06837764.7T patent/DK1951866T3/da active
- 2006-11-16 BR BRPI0620552-6A patent/BRPI0620552A2/pt not_active IP Right Cessation
- 2006-11-16 EP EP06837908A patent/EP1957641A2/en not_active Withdrawn
- 2006-11-16 KR KR1020087015062A patent/KR20080071190A/ko not_active Withdrawn
- 2006-11-16 US US11/992,899 patent/US8049062B2/en not_active Expired - Fee Related
- 2006-11-16 AU AU2006316610A patent/AU2006316610B2/en not_active Ceased
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- 2006-11-16 CA CA2624661A patent/CA2624661C/en not_active Expired - Fee Related
- 2006-11-16 EP EP06837764.7A patent/EP1951866B1/en not_active Not-in-force
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2008
- 2008-06-02 NO NO20082466A patent/NO20082466L/no not_active Application Discontinuation
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2009
- 2009-11-17 US US12/619,706 patent/US8048653B2/en active Active
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2010
- 2010-03-17 US US12/725,482 patent/US8420892B2/en active Active
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2013
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