JP2004508327A5 - - Google Patents

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Publication number
JP2004508327A5
JP2004508327A5 JP2002524492A JP2002524492A JP2004508327A5 JP 2004508327 A5 JP2004508327 A5 JP 2004508327A5 JP 2002524492 A JP2002524492 A JP 2002524492A JP 2002524492 A JP2002524492 A JP 2002524492A JP 2004508327 A5 JP2004508327 A5 JP 2004508327A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002524492A
Other languages
Japanese (ja)
Other versions
JP2004508327A (ja
Filing date
Publication date
Priority claimed from US09/655,760 external-priority patent/US6414016B1/en
Application filed filed Critical
Publication of JP2004508327A publication Critical patent/JP2004508327A/ja
Publication of JP2004508327A5 publication Critical patent/JP2004508327A5/ja
Pending legal-status Critical Current

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JP2002524492A 2000-09-05 2001-09-04 下剤組成物 Pending JP2004508327A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/655,760 US6414016B1 (en) 2000-09-05 2000-09-05 Anti-constipation composition
PCT/JP2001/007628 WO2002020007A1 (en) 2000-09-05 2001-09-04 Cathartic composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009050902A Division JP4684334B2 (ja) 2000-09-05 2009-03-04 下剤組成物

Publications (2)

Publication Number Publication Date
JP2004508327A JP2004508327A (ja) 2004-03-18
JP2004508327A5 true JP2004508327A5 (enExample) 2005-12-22

Family

ID=24630250

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2002524492A Pending JP2004508327A (ja) 2000-09-05 2001-09-04 下剤組成物
JP2009050902A Expired - Fee Related JP4684334B2 (ja) 2000-09-05 2009-03-04 下剤組成物
JP2009213058A Pending JP2009286806A (ja) 2000-09-05 2009-09-15 下剤組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009050902A Expired - Fee Related JP4684334B2 (ja) 2000-09-05 2009-03-04 下剤組成物
JP2009213058A Pending JP2009286806A (ja) 2000-09-05 2009-09-15 下剤組成物

Country Status (25)

Country Link
US (7) US6414016B1 (enExample)
EP (2) EP1857105B1 (enExample)
JP (3) JP2004508327A (enExample)
KR (2) KR100901102B1 (enExample)
CN (1) CN100335049C (enExample)
AR (2) AR030609A1 (enExample)
AT (1) ATE476975T1 (enExample)
AU (2) AU2001282615B2 (enExample)
BR (1) BRPI0114042B8 (enExample)
CA (1) CA2419741C (enExample)
CZ (1) CZ304740B6 (enExample)
DE (2) DE60142810D1 (enExample)
DK (2) DK1857105T3 (enExample)
ES (2) ES2347697T3 (enExample)
HU (1) HU229319B1 (enExample)
IL (2) IL154534A0 (enExample)
MX (1) MXPA03001959A (enExample)
NL (1) NL300757I2 (enExample)
NO (1) NO332701B1 (enExample)
NZ (1) NZ524401A (enExample)
PT (2) PT1857105E (enExample)
RU (1) RU2694361C3 (enExample)
TW (1) TWI305147B (enExample)
WO (1) WO2002020007A1 (enExample)
ZA (1) ZA200301673B (enExample)

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TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
TWI263505B (en) * 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener
ES2379652T3 (es) * 2002-10-23 2012-04-30 Sucampo Ag Compuestos de prostaglandina para el tratamiento de obesidad
NZ541110A (en) * 2002-12-27 2008-11-28 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
WO2005002588A1 (en) * 2003-07-03 2005-01-13 Sucampo Ag Enteric coated composition comprising prostaglandin analogs as chloride channel opener
TWI348386B (en) * 2003-08-12 2011-09-11 R Tech Ueno Ltd Composition and method for promoting hair growth
RU2392941C2 (ru) * 2004-09-02 2010-06-27 Сукампо Аг Производные простагландинов для лечения желудочно-кишечного нарушения
TWI387454B (zh) * 2004-09-02 2013-03-01 蘇坎波公司 治療胃腸道疾病之方法及組成物
PL1841433T3 (pl) * 2005-01-27 2012-07-31 Sucampo Ag Kompozycja do leczenia zaburzeń ośrodkowego układu nerwowego
KR101623205B1 (ko) 2005-03-04 2016-05-20 수캄포 아게 말초 혈관 질환 치료를 위한 방법 및 조성물
JP5241484B2 (ja) * 2005-03-07 2013-07-17 ザ ユニヴァーシティー オヴ シカゴ 内皮細胞増殖及び内皮細胞遊走を減弱するためのオピオイドアンタゴニストの使用
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
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JP5711442B2 (ja) * 2005-04-12 2015-04-30 スキャンポ・アーゲーＳｕｃａｍｐｏ ＡＧ 胃腸障害の処置のためのプロスタグランジン化合物およびプロトンポンプ阻害剤の併用
EP2682130A1 (en) * 2006-01-24 2014-01-08 R-Tech Ueno, Ltd. Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound
KR101353187B1 (ko) * 2006-02-07 2014-01-17 수캄포 아게 프로스타글란딘 유도체의 제조 방법
US20090012165A1 (en) 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
US20090030072A1 (en) 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
CN101318948B (zh) * 2008-04-01 2011-04-27 上海天伟生物制药有限公司 鲁比前列酮晶体、其制备方法及用途
US8513441B2 (en) * 2008-08-29 2013-08-20 Alphora Research Inc. Prostaglandin synthesis and intermediates for use therein
PT2349250T (pt) * 2008-10-31 2017-07-25 Lipid Pharmaceuticals Ehf Ácidos gordos para uso como um medicamento
EP3939964A1 (en) 2008-12-31 2022-01-19 Ardelyx, Inc. Combinations for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
WO2010083597A1 (en) 2009-01-22 2010-07-29 Apotex Pharmachem Inc. Methods of making lubiprostone and intermediates thereof
US9084815B2 (en) * 2009-09-16 2015-07-21 Sucampo Ag Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor
MX342548B (es) * 2009-09-18 2016-10-04 Merck Sharp & Dohme Corp * Uso del antagonista del receptor opiaceo para los trastornos del tracto gastrointestinal.
CA2779736A1 (en) * 2009-11-03 2011-05-12 Bernard Charles Sherman Stable pharmaceutical formulations comprising lubiprostone
CA2784933A1 (en) * 2009-12-18 2011-06-23 Apotex Pharmachem Inc. Processes for the purification of lubiprostone
US8785663B2 (en) 2010-01-28 2014-07-22 Alfredo Paul Ceccarelli Polymorphic forms of Lubiprostone
US10376481B2 (en) 2012-08-21 2019-08-13 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
CN104902930A (zh) 2012-08-21 2015-09-09 阿德利克斯公司 在治疗与液体潴留或盐分过载相关的疾病和胃肠道疾病中用于抑制nhe-介导的反向转运的化合物和方法
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
CA2909169A1 (en) 2013-04-12 2014-10-16 Ardelyx, Inc. Nhe3-binding compounds and methods for inhibiting phosphate transport
EP3277274B1 (en) 2015-04-01 2024-06-12 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
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WO2018065826A1 (en) 2016-10-06 2018-04-12 Sucampo Ag Multilayer beads for pharmaceutical use
EP3565811A1 (en) 2017-01-09 2019-11-13 Ardelyx, Inc. Inhibitors of nhe-mediated antiport
CN110267944B (zh) 2017-01-09 2024-03-08 阿德利克斯股份有限公司 可用于治疗胃肠道病症的化合物
JP6750733B2 (ja) * 2017-04-20 2020-09-02 株式会社島津製作所 分光光度計
US10422729B1 (en) 2019-03-08 2019-09-24 Biodesix, Inc. Blood sample separation devices and methods

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CA2030346C (en) * 1989-11-22 2000-04-11 Ryuji Ueno Treatment of cardiac dysfunction with 15-keto-prostaglandin compounds
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PT1220849E (pt) * 1999-10-15 2004-10-29 Sucampo Ag Composicao de compostos biciclicos e metodo para a sua estabilizacao
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