AR105029A1 - Composición farmacéutica que comprende derivado de ácido graso - Google Patents
Composición farmacéutica que comprende derivado de ácido grasoInfo
- Publication number
- AR105029A1 AR105029A1 ARP160101808A ARP160101808A AR105029A1 AR 105029 A1 AR105029 A1 AR 105029A1 AR P160101808 A ARP160101808 A AR P160101808A AR P160101808 A ARP160101808 A AR P160101808A AR 105029 A1 AR105029 A1 AR 105029A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydroxy
- group
- halogen
- aliphatic hydrocarbon
- substituted
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Reivindicación 1: Una composición farmacéutica oral que comprende: (a) un derivado de ácido graso representado por la fórmula (1) donde L, M y N son hidrógeno, hidroxi, halógeno, alquilo inferior, hidroxialquilo inferior, alcanoiloxi inferior u oxo, donde por lo menos uno de L y M es un grupo diferente de hidrógeno, y el anillo de cinco miembros puede tener por lo menos un enlace doble; A es -CH₃, o -CH₂OH, -COCH₂OH, -COOH o un derivado funcional de estos; B es un enlace único, -CH₂-CH₂-, -CH=CH-, -CºC-, -CH₂-CH₂-CH₂-, -CH=CH-CH₂-, -CH₂-CH=CH-, -CºC-CH₂- o -CH₂-CºC-; Z es un compuesto del grupo de fórmulas (2) o enlace único, donde R⁴ y R⁵ son hidrógeno, hidroxi, halógeno, alquilo inferior, alcoxi inferior o hidroxialquilo inferior, donde R⁴ y R⁵ no son hidroxi y alcoxi inferior al mismo tiempo; R¹ es un residuo hidrocarburo alifático medio o inferior bivalente saturado o insaturado, que no está sustituido o está sustituido con halógeno, alquilo inferior, hidroxi, oxo, arilo o grupo heterocíclico, y por lo menos uno de los átomos de carbono en el hidrocarburo alifático está opcionalmente sustituido con oxígeno, nitrógeno o azufre; y Rᵃ es un residuo hidrocarburo alifático medio o inferior, saturado o insaturado, que no está sustituido o está sustituido con halógeno, oxo, hidroxi, alquilo inferior, alcoxi inferior, alcanoiloxi inferior, cicloalquilo inferior, cicloalquiloxi inferior, arilo, ariloxi, grupo heterocíclico o grupo heterocíclico-oxi; alcoxi inferior; alcanoiloxi inferior; cicloalquilo inferior; cicloalquiloxi inferior; arilo; ariloxi; grupo heterocíclico; grupo heterocíclico-oxi, y por lo menos uno de los átomos de carbono en el hidrocarburo alifático está opcionalmente sustituido con oxígeno, nitrógeno o azufre; (b) un agente edulcorante seleccionado del grupo que consiste en neotame, sacarina, sucralosa y una de sus mezclas; y (c) un vehículo oleoso farmacéuticamente aceptable. Reivindicación 6: La composición como se describe en la reivindicación 1, donde el derivado de ácido graso es ácido (-)-7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentil)-2-hidroxi-6-oxooctahidrociclopenta[b]piran-5-il]heptanoico o ácido (-)-7-{(2R,4aR,5R,7aR)-2-[(3S)-1,1-difluoro-3-metilopentil]-2-hidroxi-6-oxooctahidrociclopenta[b]piran-5-il}heptanoico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562182084P | 2015-06-19 | 2015-06-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR105029A1 true AR105029A1 (es) | 2017-08-30 |
Family
ID=56852296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP160101808A AR105029A1 (es) | 2015-06-19 | 2016-06-16 | Composición farmacéutica que comprende derivado de ácido graso |
Country Status (4)
Country | Link |
---|---|
US (1) | US20170020890A1 (es) |
AR (1) | AR105029A1 (es) |
TW (1) | TW201705952A (es) |
WO (1) | WO2016203317A1 (es) |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
CA1322749C (en) | 1987-01-28 | 1993-10-05 | Ryuzo Ueno | Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
US5428062A (en) | 1987-01-28 | 1995-06-27 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti ulcers containing same |
US5225439A (en) | 1987-01-28 | 1993-07-06 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti ulcers containing same |
US5591887A (en) | 1987-04-30 | 1997-01-07 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
CA1324129C (en) | 1987-04-30 | 1993-11-09 | Ryuzo Ueno | Prostaglandins of the f series |
US5221763A (en) | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
CA2039420C (en) | 1990-04-04 | 1996-12-10 | Ryuji Ueno | Treatment of cataract with 15-keto-prostaglandin compounds |
CA2150287C (en) | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
DE69714698T2 (de) | 1996-06-10 | 2002-12-05 | Sucampo Ag | Endothelin-antagonisten |
US6414016B1 (en) * | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
CA2870252A1 (en) * | 2012-04-23 | 2013-10-31 | Sucampo Ag | Method for treating irritable bowel syndrome with diarrhea |
-
2016
- 2016-06-16 US US15/184,474 patent/US20170020890A1/en not_active Abandoned
- 2016-06-16 AR ARP160101808A patent/AR105029A1/es unknown
- 2016-06-16 WO PCT/IB2016/001005 patent/WO2016203317A1/en active Application Filing
- 2016-06-17 TW TW105119166A patent/TW201705952A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
TW201705952A (zh) | 2017-02-16 |
US20170020890A1 (en) | 2017-01-26 |
WO2016203317A1 (en) | 2016-12-22 |
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