JP2002536978A5 - - Google Patents
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- Publication number
- JP2002536978A5 JP2002536978A5 JP2000599878A JP2000599878A JP2002536978A5 JP 2002536978 A5 JP2002536978 A5 JP 2002536978A5 JP 2000599878 A JP2000599878 A JP 2000599878A JP 2000599878 A JP2000599878 A JP 2000599878A JP 2002536978 A5 JP2002536978 A5 JP 2002536978A5
- Authority
- JP
- Japan
- Prior art keywords
- dna molecule
- sequence
- plant
- insect
- glcnac
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004414 DNA Proteins 0.000 description 28
- 102000053602 DNA Human genes 0.000 description 25
- 238000000034 method Methods 0.000 description 24
- 241000238631 Hexapoda Species 0.000 description 15
- 102000003886 Glycoproteins Human genes 0.000 description 9
- 108090000288 Glycoproteins Proteins 0.000 description 9
- 108010001671 galactoside 3-fucosyltransferase Proteins 0.000 description 9
- 239000013598 vector Substances 0.000 description 6
- 108091093037 Peptide nucleic acid Proteins 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 230000000295 complement effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 125000002446 fucosyl group Chemical group C1([C@@H](O)[C@H](O)[C@H](O)[C@@H](O1)C)* 0.000 description 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 2
- 102000053642 Catalytic RNA Human genes 0.000 description 2
- 108090000994 Catalytic RNA Proteins 0.000 description 2
- 102000004357 Transferases Human genes 0.000 description 2
- 108090000992 Transferases Proteins 0.000 description 2
- 238000010367 cloning Methods 0.000 description 2
- 230000002068 genetic effect Effects 0.000 description 2
- 230000035772 mutation Effects 0.000 description 2
- 230000006798 recombination Effects 0.000 description 2
- 238000005215 recombination Methods 0.000 description 2
- 108091092562 ribozyme Proteins 0.000 description 2
- 108010019236 Fucosyltransferases Proteins 0.000 description 1
- 102000006471 Fucosyltransferases Human genes 0.000 description 1
- 108700023372 Glycosyltransferases Proteins 0.000 description 1
- 102000051366 Glycosyltransferases Human genes 0.000 description 1
- 102100034343 Integrase Human genes 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 108010064851 Plant Proteins Proteins 0.000 description 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 235000021118 plant-derived protein Nutrition 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000010839 reverse transcription Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0027099A AT408446B (de) | 1999-02-18 | 1999-02-18 | Fucosyltransferase-gen |
| AT270/99 | 1999-02-18 | ||
| ATA270/99 | 1999-02-18 | ||
| PCT/AT2000/000040 WO2000049153A1 (de) | 1999-02-18 | 2000-02-17 | Fucosyltransferase-gen |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011000049A Division JP2011120592A (ja) | 1999-02-18 | 2011-01-04 | フコシルトランスフェラーゼ遺伝子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002536978A JP2002536978A (ja) | 2002-11-05 |
| JP2002536978A5 true JP2002536978A5 (https=) | 2007-02-15 |
| JP5514386B2 JP5514386B2 (ja) | 2014-06-04 |
Family
ID=3486087
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000599878A Expired - Lifetime JP5514386B2 (ja) | 1999-02-18 | 2000-02-17 | フコシルトランスフェラーゼ遺伝子 |
| JP2011000049A Pending JP2011120592A (ja) | 1999-02-18 | 2011-01-04 | フコシルトランスフェラーゼ遺伝子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011000049A Pending JP2011120592A (ja) | 1999-02-18 | 2011-01-04 | フコシルトランスフェラーゼ遺伝子 |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US20080234471A1 (https=) |
| EP (3) | EP1642979A1 (https=) |
| JP (2) | JP5514386B2 (https=) |
| KR (1) | KR20010108234A (https=) |
| CN (1) | CN1360633A (https=) |
| AT (2) | AT408446B (https=) |
| AU (1) | AU771995B2 (https=) |
| BG (1) | BG65140B1 (https=) |
| BR (1) | BR0010114A (https=) |
| CA (1) | CA2362964C (https=) |
| CZ (2) | CZ308081B6 (https=) |
| DE (1) | DE50011116D1 (https=) |
| DK (2) | DK2062977T3 (https=) |
| EE (1) | EE200100432A (https=) |
| ES (2) | ES2444126T3 (https=) |
| HR (1) | HRP20010681A2 (https=) |
| HU (1) | HU230075B1 (https=) |
| IL (2) | IL144777A0 (https=) |
| IS (1) | IS6041A (https=) |
| MX (1) | MXPA01008372A (https=) |
| NO (1) | NO20013993L (https=) |
| NZ (1) | NZ513685A (https=) |
| PL (2) | PL205710B1 (https=) |
| PT (1) | PT2062977E (https=) |
| SK (1) | SK286416B6 (https=) |
| TR (1) | TR200102393T2 (https=) |
| WO (1) | WO2000049153A1 (https=) |
| YU (1) | YU58901A (https=) |
| ZA (1) | ZA200106735B (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1137789T3 (da) | 1998-12-09 | 2010-11-08 | Phyton Holdings Llc | Fremgangsmåde til fremstilling af et glycoprotein med glycosylering af human type |
| AT408446B (de) * | 1999-02-18 | 2001-11-26 | Altmann Friedrich Dr | Fucosyltransferase-gen |
| CA2704600C (en) | 1999-04-09 | 2016-10-25 | Kyowa Kirin Co., Ltd. | A method for producing antibodies with increased adcc activity |
| DE60044858D1 (de) | 1999-10-26 | 2010-09-30 | Stichting Dienst Landbouwkundi | Säugetierartige Glykosylierung in Pflanzen |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| DK1356068T3 (en) | 2001-01-19 | 2015-02-16 | Phyton Holdings Llc | PROCESS FOR THE PRODUCTION OF secretory glycoprotein with HUMAN TYPE SUGAR CHAIN FOR USING A PLANT CELL |
| CN101613705A (zh) | 2002-03-19 | 2009-12-30 | 国际植物研究所 | 在植物中优化聚糖生成 |
| CN1665934B (zh) | 2002-03-19 | 2010-05-26 | 国际植物研究所 | GNTIII(UDP-N乙酰葡萄糖胺:β-D-甘露糖苷β(1,4)-N-乙酰葡萄糖胺基-转移酶III)在植物中的表达 |
| ATE503829T1 (de) | 2002-04-09 | 2011-04-15 | Kyowa Hakko Kirin Co Ltd | Zelle mit erniedrigter oder deletierter aktivität eines am gdp-fucosetransport beteiligten proteins |
| CL2003002461A1 (es) | 2002-11-27 | 2005-01-07 | Dow Chemical Company Agroscien | Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas. |
| EP1510584B1 (en) | 2003-08-11 | 2009-03-18 | Greenovation Biotech GmbH | Expression promoting sequences from mosses and their uses |
| FI20055398A0 (fi) | 2005-07-08 | 2005-07-08 | Suomen Punainen Risti Veripalv | Menetelmä solupopulaatioiden evaluoimiseksi |
| JP2009526520A (ja) | 2006-01-17 | 2009-07-23 | バイオレックス セラピュティックス インク | 植物中でのｎ−グリカンのヒト化及び最適化のための組成物及び方法 |
| US20090060921A1 (en) * | 2006-01-17 | 2009-03-05 | Biolex Therapeutics, Inc. | Glycan-optimized anti-cd20 antibodies |
| CN102094019B (zh) * | 2007-01-15 | 2012-11-28 | 燕秋 | 用于抑制LeY糖抗原合成的岩藻糖基转移酶Ⅳ的RNA干涉序列及重组干涉质粒 |
| CN102094020B (zh) * | 2007-01-15 | 2012-11-28 | 燕秋 | 用于抑制LeY糖抗原合成的岩藻糖基转移酶I的RNA干涉序列及重组干涉质粒 |
| WO2008125972A2 (en) | 2007-04-17 | 2008-10-23 | Plant Research International B.V. | Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases |
| WO2009033011A1 (en) * | 2007-09-07 | 2009-03-12 | Children's Hospital Medical Center | Use of secretor, lewis and sialyl antigen levels as predictors for disease |
| WO2009056155A1 (en) * | 2007-10-31 | 2009-05-07 | Bayer Bioscience N.V. | Method to produce modified plants with altered n-glycosylation pattern |
| EP2166085A1 (en) | 2008-07-16 | 2010-03-24 | Suomen Punainen Risti Veripalvelu | Divalent modified cells |
| EP2944690B1 (en) | 2010-10-11 | 2017-12-20 | Jennewein Biotechnologie GmbH | Novel fucosyltransferases and their applications |
| KR101293658B1 (ko) * | 2010-12-30 | 2013-08-07 | 대한민국 | 알파-1,3-푸코실트랜스퍼라아제 및/또는 베타-1,2-자일로실트렌스퍼라아제 유전자를 포함하는 벼 형질전환용 벡터 및 형질전환된 벼 |
| EP2479263B1 (en) * | 2011-01-20 | 2013-11-27 | Jennewein Biotechnologie GmbH | Novel Fucosyltransferases and their applications |
| EP2789686A1 (en) | 2013-04-11 | 2014-10-15 | Greenovation Biotech GmbH | Expression of phosphorylated glycoproteins in plants |
| EP3050973A1 (en) * | 2015-01-30 | 2016-08-03 | Jennewein Biotechnologie GmbH | Fermentation process for producing monosaccharides in free form from nucleotide-activated sugars |
| CN110317799B (zh) * | 2019-07-18 | 2026-04-03 | 江南大学 | 一种人源岩藻糖转移酶8的原核表达方法及其产品 |
| EP3871687A1 (en) | 2020-02-27 | 2021-09-01 | eleva GmbH | Enzyme replacement therapy for treating pompe disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5272066A (en) | 1986-03-07 | 1993-12-21 | Massachusetts Institute Of Technology | Synthetic method for enhancing glycoprotein stability |
| JP3756946B2 (ja) | 1993-03-29 | 2006-03-22 | 協和醗酵工業株式会社 | α１，３−フコシルトランスフェラーゼ |
| US6509149B2 (en) * | 1995-06-06 | 2003-01-21 | Hybridon, Inc. | HPV-specific oligonucleotides |
| US5770420A (en) * | 1995-09-08 | 1998-06-23 | The Regents Of The University Of Michigan | Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures |
| AT408446B (de) * | 1999-02-18 | 2001-11-26 | Altmann Friedrich Dr | Fucosyltransferase-gen |
-
1999
- 1999-02-18 AT AT0027099A patent/AT408446B/de not_active IP Right Cessation
-
2000
- 2000-02-17 PL PL385768A patent/PL205710B1/pl unknown
- 2000-02-17 CN CN00805192A patent/CN1360633A/zh active Pending
- 2000-02-17 EP EP05108012A patent/EP1642979A1/de not_active Withdrawn
- 2000-02-17 KR KR1020017010518A patent/KR20010108234A/ko not_active Ceased
- 2000-02-17 DK DK09154489.0T patent/DK2062977T3/da active
- 2000-02-17 DE DE50011116T patent/DE50011116D1/de not_active Expired - Lifetime
- 2000-02-17 WO PCT/AT2000/000040 patent/WO2000049153A1/de not_active Ceased
- 2000-02-17 PL PL363438A patent/PL205785B1/pl unknown
- 2000-02-17 CA CA2362964A patent/CA2362964C/en not_active Expired - Lifetime
- 2000-02-17 PT PT91544890T patent/PT2062977E/pt unknown
- 2000-02-17 EP EP00904677A patent/EP1151109B1/de not_active Expired - Lifetime
- 2000-02-17 CZ CZ2008-404A patent/CZ308081B6/cs not_active IP Right Cessation
- 2000-02-17 EE EEP200100432A patent/EE200100432A/xx unknown
- 2000-02-17 DK DK00904677T patent/DK1151109T3/da active
- 2000-02-17 SK SK1118-2001A patent/SK286416B6/sk not_active IP Right Cessation
- 2000-02-17 BR BR0010114-1A patent/BR0010114A/pt not_active Application Discontinuation
- 2000-02-17 AT AT00904677T patent/ATE304053T1/de active
- 2000-02-17 HR HR20010681A patent/HRP20010681A2/hr not_active Application Discontinuation
- 2000-02-17 EP EP09154489.0A patent/EP2062977B1/de not_active Expired - Lifetime
- 2000-02-17 AU AU26460/00A patent/AU771995B2/en not_active Expired
- 2000-02-17 JP JP2000599878A patent/JP5514386B2/ja not_active Expired - Lifetime
- 2000-02-17 YU YU58901A patent/YU58901A/sh unknown
- 2000-02-17 ES ES09154489.0T patent/ES2444126T3/es not_active Expired - Lifetime
- 2000-02-17 ES ES00904677T patent/ES2246222T3/es not_active Expired - Lifetime
- 2000-02-17 NZ NZ513685A patent/NZ513685A/en unknown
- 2000-02-17 CZ CZ20012943A patent/CZ299622B6/cs not_active IP Right Cessation
- 2000-02-17 HU HU0200394A patent/HU230075B1/hu unknown
- 2000-02-17 IL IL14477700A patent/IL144777A0/xx active IP Right Grant
- 2000-02-17 TR TR2001/02393T patent/TR200102393T2/xx unknown
- 2000-02-17 MX MXPA01008372A patent/MXPA01008372A/es active IP Right Grant
-
2001
- 2001-08-07 IL IL144777A patent/IL144777A/en not_active IP Right Cessation
- 2001-08-08 IS IS6041A patent/IS6041A/is unknown
- 2001-08-15 ZA ZA200106735A patent/ZA200106735B/en unknown
- 2001-08-16 NO NO20013993A patent/NO20013993L/no unknown
- 2001-09-13 BG BG105899A patent/BG65140B1/bg unknown
-
2007
- 2007-06-06 US US11/808,096 patent/US20080234471A1/en not_active Abandoned
- 2007-06-06 US US11/808,097 patent/US8198078B2/en not_active Expired - Fee Related
-
2011
- 2011-01-04 JP JP2011000049A patent/JP2011120592A/ja active Pending
-
2012
- 2012-05-15 US US13/471,759 patent/US8895806B2/en not_active Expired - Fee Related
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