JP2004500096A5 - - Google Patents
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- Publication number
- JP2004500096A5 JP2004500096A5 JP2001563590A JP2001563590A JP2004500096A5 JP 2004500096 A5 JP2004500096 A5 JP 2004500096A5 JP 2001563590 A JP2001563590 A JP 2001563590A JP 2001563590 A JP2001563590 A JP 2001563590A JP 2004500096 A5 JP2004500096 A5 JP 2004500096A5
- Authority
- JP
- Japan
- Prior art keywords
- dna molecule
- plant
- xylosyltransferase
- sequence
- glycoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004414 DNA Proteins 0.000 description 23
- 102000053602 DNA Human genes 0.000 description 20
- 102000003886 Glycoproteins Human genes 0.000 description 12
- 108090000288 Glycoproteins Proteins 0.000 description 12
- 108010044310 beta 1,2-xylosyltransferase Proteins 0.000 description 12
- 238000004519 manufacturing process Methods 0.000 description 12
- 238000000034 method Methods 0.000 description 11
- 108090000994 Catalytic RNA Proteins 0.000 description 3
- 102000053642 Catalytic RNA Human genes 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 108091092562 ribozyme Proteins 0.000 description 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 108010029485 Protein Isoforms Proteins 0.000 description 2
- 102000001708 Protein Isoforms Human genes 0.000 description 2
- 150000001720 carbohydrates Chemical group 0.000 description 2
- 238000001890 transfection Methods 0.000 description 2
- 238000000018 DNA microarray Methods 0.000 description 1
- 102100034343 Integrase Human genes 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 1
- 108010065282 UDP xylose-protein xylosyltransferase Proteins 0.000 description 1
- DQQDLYVHOTZLOR-OCIMBMBZSA-N UDP-alpha-D-xylose Chemical compound C([C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(=O)C=C1)=O)O)O)OP(O)(=O)OP(O)(=O)O[C@H]1OC[C@@H](O)[C@H](O)[C@H]1O DQQDLYVHOTZLOR-OCIMBMBZSA-N 0.000 description 1
- DQQDLYVHOTZLOR-UHFFFAOYSA-N UDP-alpha-D-xylose Natural products O1C(N2C(NC(=O)C=C2)=O)C(O)C(O)C1COP(O)(=O)OP(O)(=O)OC1OCC(O)C(O)C1O DQQDLYVHOTZLOR-UHFFFAOYSA-N 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 102000010199 Xylosyltransferases Human genes 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 125000001183 hydrocarbyl group Chemical group 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0035500A AT409381B (de) | 2000-03-03 | 2000-03-03 | Xylosyltransferase-gen |
| ATA355/2000 | 2000-03-03 | ||
| PCT/EP2001/002352 WO2001064901A1 (en) | 2000-03-03 | 2001-03-02 | Beta 1, 2-xylosyltransferase-gene from arabidopsis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013005404A Division JP2013116113A (ja) | 2000-03-03 | 2013-01-16 | アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004500096A JP2004500096A (ja) | 2004-01-08 |
| JP2004500096A5 true JP2004500096A5 (https=) | 2008-03-21 |
| JP5279976B2 JP5279976B2 (ja) | 2013-09-04 |
Family
ID=3672559
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001563590A Expired - Lifetime JP5279976B2 (ja) | 2000-03-03 | 2001-03-02 | アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子 |
| JP2013005404A Pending JP2013116113A (ja) | 2000-03-03 | 2013-01-16 | アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013005404A Pending JP2013116113A (ja) | 2000-03-03 | 2013-01-16 | アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7205137B2 (https=) |
| EP (2) | EP1621633B1 (https=) |
| JP (2) | JP5279976B2 (https=) |
| KR (5) | KR100861437B1 (https=) |
| AT (2) | AT409381B (https=) |
| AU (1) | AU781010B2 (https=) |
| CA (1) | CA2402015C (https=) |
| DE (1) | DE60115863T3 (https=) |
| DK (2) | DK1621633T3 (https=) |
| ES (2) | ES2252208T5 (https=) |
| PT (1) | PT1621633E (https=) |
| WO (1) | WO2001064901A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1137789T3 (da) | 1998-12-09 | 2010-11-08 | Phyton Holdings Llc | Fremgangsmåde til fremstilling af et glycoprotein med glycosylering af human type |
| DE60044858D1 (de) | 1999-10-26 | 2010-09-30 | Stichting Dienst Landbouwkundi | Säugetierartige Glykosylierung in Pflanzen |
| DK1356068T3 (en) | 2001-01-19 | 2015-02-16 | Phyton Holdings Llc | PROCESS FOR THE PRODUCTION OF secretory glycoprotein with HUMAN TYPE SUGAR CHAIN FOR USING A PLANT CELL |
| CN101613705A (zh) | 2002-03-19 | 2009-12-30 | 国际植物研究所 | 在植物中优化聚糖生成 |
| CN1665934B (zh) | 2002-03-19 | 2010-05-26 | 国际植物研究所 | GNTIII(UDP-N乙酰葡萄糖胺:β-D-甘露糖苷β(1,4)-N-乙酰葡萄糖胺基-转移酶III)在植物中的表达 |
| CL2003002461A1 (es) | 2002-11-27 | 2005-01-07 | Dow Chemical Company Agroscien | Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas. |
| EP1510584B1 (en) | 2003-08-11 | 2009-03-18 | Greenovation Biotech GmbH | Expression promoting sequences from mosses and their uses |
| JP2009526520A (ja) * | 2006-01-17 | 2009-07-23 | バイオレックス セラピュティックス インク | 植物中でのｎ−グリカンのヒト化及び最適化のための組成物及び方法 |
| US20090060921A1 (en) * | 2006-01-17 | 2009-03-05 | Biolex Therapeutics, Inc. | Glycan-optimized anti-cd20 antibodies |
| CA2646583A1 (en) * | 2006-03-23 | 2007-09-27 | Bayer Bioscience N.V. | Novel nucleotide sequences encoding nicotiana beta-1,2-xylosyltransferase |
| WO2008125972A2 (en) | 2007-04-17 | 2008-10-23 | Plant Research International B.V. | Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases |
| RU2485180C2 (ru) | 2007-06-07 | 2013-06-20 | Эгрикалча Энд Эгри-Фуд Кэнэда | Способ трансфекции и трансдукции растительных клеток |
| EP2789686A1 (en) | 2013-04-11 | 2014-10-15 | Greenovation Biotech GmbH | Expression of phosphorylated glycoproteins in plants |
| JP6934666B2 (ja) * | 2018-01-18 | 2021-09-15 | 国立研究開発法人産業技術総合研究所 | 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法 |
| EP3871687A1 (en) | 2020-02-27 | 2021-09-01 | eleva GmbH | Enzyme replacement therapy for treating pompe disease |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69631540T2 (de) * | 1995-11-23 | 2005-01-27 | Cancer Research Technology Ltd. | Materialien und methoden mit bezug zur identifizierung und sequenzierung des krebs-suszeptilitaetsgens brca2 und dessen anwendungen |
| AU1808699A (en) * | 1997-12-08 | 1999-06-28 | Board Of Trustees Of The University Of Arkansas, The | Purified beta1,2-xylosyltransferase and uses thereof |
| DE19754622A1 (de) † | 1997-12-09 | 1999-06-10 | Antje Von Dr Schaewen | Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität |
| WO1999032623A1 (en) * | 1997-12-19 | 1999-07-01 | Pharmacia & Upjohn Company | Human sel-10 polypeptides and polynucleotides that encode them |
| US6207811B1 (en) * | 1998-03-18 | 2001-03-27 | Karl Tryggvason | Nephrin gene and protein |
| EP1105479B1 (en) * | 1998-08-11 | 2011-01-12 | Darwin Discovery Limited | Identification of the gene causing the mouse scurfy phenotype and its human ortholog |
| EP1033405A3 (en) * | 1999-02-25 | 2001-08-01 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
| BR0014945A (pt) * | 1999-10-21 | 2004-08-31 | Monsanto Co | Modificação pós-traducional de proteìnas recombinantes produzidas em plantas |
-
2000
- 2000-03-03 AT AT0035500A patent/AT409381B/de not_active IP Right Cessation
-
2001
- 2001-03-02 ES ES01919367.1T patent/ES2252208T5/es not_active Expired - Lifetime
- 2001-03-02 KR KR1020027011341A patent/KR100861437B1/ko not_active Expired - Lifetime
- 2001-03-02 PT PT51080141T patent/PT1621633E/pt unknown
- 2001-03-02 AT AT01919367T patent/ATE312931T1/de active
- 2001-03-02 DK DK05108014.1T patent/DK1621633T3/da active
- 2001-03-02 AU AU46495/01A patent/AU781010B2/en not_active Expired
- 2001-03-02 ES ES05108014.1T patent/ES2460672T3/es not_active Expired - Lifetime
- 2001-03-02 US US10/220,467 patent/US7205137B2/en not_active Expired - Lifetime
- 2001-03-02 KR KR1020097019435A patent/KR20090101981A/ko not_active Ceased
- 2001-03-02 KR KR1020107023909A patent/KR101185123B1/ko not_active Expired - Lifetime
- 2001-03-02 KR KR1020077011024A patent/KR100859919B1/ko not_active Expired - Lifetime
- 2001-03-02 DK DK01919367.1T patent/DK1263968T4/da active
- 2001-03-02 EP EP05108014.1A patent/EP1621633B1/en not_active Expired - Lifetime
- 2001-03-02 EP EP01919367.1A patent/EP1263968B2/en not_active Expired - Lifetime
- 2001-03-02 DE DE60115863.6T patent/DE60115863T3/de not_active Expired - Lifetime
- 2001-03-02 WO PCT/EP2001/002352 patent/WO2001064901A1/en not_active Ceased
- 2001-03-02 JP JP2001563590A patent/JP5279976B2/ja not_active Expired - Lifetime
- 2001-03-02 CA CA2402015A patent/CA2402015C/en not_active Expired - Lifetime
- 2001-03-02 KR KR1020087019207A patent/KR20080077296A/ko not_active Ceased
-
2007
- 2007-03-12 US US11/684,898 patent/US20070186311A1/en not_active Abandoned
-
2012
- 2012-03-23 US US13/428,777 patent/US20120331578A1/en not_active Abandoned
-
2013
- 2013-01-16 JP JP2013005404A patent/JP2013116113A/ja active Pending
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