KR100861437B1 - 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자 - Google Patents

아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자 Download PDF

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KR100861437B1
KR100861437B1 KR1020027011341A KR20027011341A KR100861437B1 KR 100861437 B1 KR100861437 B1 KR 100861437B1 KR 1020027011341 A KR1020027011341 A KR 1020027011341A KR 20027011341 A KR20027011341 A KR 20027011341A KR 100861437 B1 KR100861437 B1 KR 100861437B1
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sequence
dna
delete delete
dna molecule
xylsilyltransferase
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KR20030030987A (ko
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요세프 그뢰슬
리차드 스트라세르
잔 무카
루카스 마크
프리드리히 알트만
아인 비. 윌슨
헤르타 스타인켈너
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요세프 그뢰슬
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/02Pentosyltransferases (2.4.2)
    • C12Y204/02038Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024Alpha-mannosidase (3.2.1.24)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0105Alpha-N-acetylglucosaminidase (3.2.1.50)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052Beta-N-acetylhexosaminidase (3.2.1.52)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020027011341A 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자 Expired - Lifetime KR100861437B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen
ATA355/2000 2000-03-03
PCT/EP2001/002352 WO2001064901A1 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis

Related Child Applications (2)

Application Number Title Priority Date Filing Date
KR1020087019207A Division KR20080077296A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
KR1020077011024A Division KR100859919B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자

Publications (2)

Publication Number Publication Date
KR20030030987A KR20030030987A (ko) 2003-04-18
KR100861437B1 true KR100861437B1 (ko) 2008-10-02

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ID=3672559

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020027011341A Expired - Lifetime KR100861437B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
KR1020097019435A Ceased KR20090101981A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020107023909A Expired - Lifetime KR101185123B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020077011024A Expired - Lifetime KR100859919B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
KR1020087019207A Ceased KR20080077296A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자

Family Applications After (4)

Application Number Title Priority Date Filing Date
KR1020097019435A Ceased KR20090101981A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020107023909A Expired - Lifetime KR101185123B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020077011024A Expired - Lifetime KR100859919B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
KR1020087019207A Ceased KR20080077296A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자

Country Status (12)

Country Link
US (3) US7205137B2 (https=)
EP (2) EP1621633B1 (https=)
JP (2) JP5279976B2 (https=)
KR (5) KR100861437B1 (https=)
AT (2) AT409381B (https=)
AU (1) AU781010B2 (https=)
CA (1) CA2402015C (https=)
DE (1) DE60115863T3 (https=)
DK (2) DK1621633T3 (https=)
ES (2) ES2252208T5 (https=)
PT (1) PT1621633E (https=)
WO (1) WO2001064901A1 (https=)

Families Citing this family (15)

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Publication number Priority date Publication date Assignee Title
DK1137789T3 (da) 1998-12-09 2010-11-08 Phyton Holdings Llc Fremgangsmåde til fremstilling af et glycoprotein med glycosylering af human type
DE60044858D1 (de) 1999-10-26 2010-09-30 Stichting Dienst Landbouwkundi Säugetierartige Glykosylierung in Pflanzen
DK1356068T3 (en) 2001-01-19 2015-02-16 Phyton Holdings Llc PROCESS FOR THE PRODUCTION OF secretory glycoprotein with HUMAN TYPE SUGAR CHAIN ​​FOR USING A PLANT CELL
CN101613705A (zh) 2002-03-19 2009-12-30 国际植物研究所 在植物中优化聚糖生成
CN1665934B (zh) 2002-03-19 2010-05-26 国际植物研究所 GNTIII(UDP-N乙酰葡萄糖胺:β-D-甘露糖苷β(1,4)-N-乙酰葡萄糖胺基-转移酶III)在植物中的表达
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
EP1510584B1 (en) 2003-08-11 2009-03-18 Greenovation Biotech GmbH Expression promoting sequences from mosses and their uses
JP2009526520A (ja) * 2006-01-17 2009-07-23 バイオレックス セラピュティックス インク 植物中でのn−グリカンのヒト化及び最適化のための組成物及び方法
US20090060921A1 (en) * 2006-01-17 2009-03-05 Biolex Therapeutics, Inc. Glycan-optimized anti-cd20 antibodies
CA2646583A1 (en) * 2006-03-23 2007-09-27 Bayer Bioscience N.V. Novel nucleotide sequences encoding nicotiana beta-1,2-xylosyltransferase
WO2008125972A2 (en) 2007-04-17 2008-10-23 Plant Research International B.V. Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
RU2485180C2 (ru) 2007-06-07 2013-06-20 Эгрикалча Энд Эгри-Фуд Кэнэда Способ трансфекции и трансдукции растительных клеток
EP2789686A1 (en) 2013-04-11 2014-10-15 Greenovation Biotech GmbH Expression of phosphorylated glycoproteins in plants
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
EP3871687A1 (en) 2020-02-27 2021-09-01 eleva GmbH Enzyme replacement therapy for treating pompe disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029835A1 (en) * 1997-12-08 1999-06-17 Board Of Trustees Of The University Of Arkansas PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF

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DE69631540T2 (de) * 1995-11-23 2005-01-27 Cancer Research Technology Ltd. Materialien und methoden mit bezug zur identifizierung und sequenzierung des krebs-suszeptilitaetsgens brca2 und dessen anwendungen
DE19754622A1 (de) 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
WO1999032623A1 (en) * 1997-12-19 1999-07-01 Pharmacia & Upjohn Company Human sel-10 polypeptides and polynucleotides that encode them
US6207811B1 (en) * 1998-03-18 2001-03-27 Karl Tryggvason Nephrin gene and protein
EP1105479B1 (en) * 1998-08-11 2011-01-12 Darwin Discovery Limited Identification of the gene causing the mouse scurfy phenotype and its human ortholog
EP1033405A3 (en) * 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
BR0014945A (pt) * 1999-10-21 2004-08-31 Monsanto Co Modificação pós-traducional de proteìnas recombinantes produzidas em plantas

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1999029835A1 (en) * 1997-12-08 1999-06-17 Board Of Trustees Of The University Of Arkansas PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF

Also Published As

Publication number Publication date
CA2402015C (en) 2012-07-17
AU4649501A (en) 2001-09-12
US20120331578A1 (en) 2012-12-27
DE60115863T2 (de) 2006-08-10
DK1263968T4 (da) 2014-11-03
JP2013116113A (ja) 2013-06-13
AT409381B (de) 2002-07-25
US20040121325A1 (en) 2004-06-24
EP1621633A2 (en) 2006-02-01
KR20090101981A (ko) 2009-09-29
CA2402015A1 (en) 2001-09-07
ES2460672T3 (es) 2014-05-14
ATE312931T1 (de) 2005-12-15
DE60115863T3 (de) 2015-01-22
WO2001064901A1 (en) 2001-09-07
EP1263968B2 (en) 2014-09-10
KR20080077296A (ko) 2008-08-21
ES2252208T3 (es) 2006-05-16
AU781010B2 (en) 2005-04-28
KR20100119005A (ko) 2010-11-08
JP5279976B2 (ja) 2013-09-04
DK1263968T3 (da) 2006-05-01
JP2004500096A (ja) 2004-01-08
KR101185123B1 (ko) 2012-09-21
KR20030030987A (ko) 2003-04-18
EP1621633A3 (en) 2006-02-08
EP1263968B1 (en) 2005-12-14
US7205137B2 (en) 2007-04-17
PT1621633E (pt) 2014-07-18
KR100859919B1 (ko) 2008-09-23
ATA3552000A (de) 2001-12-15
ES2252208T5 (es) 2014-11-04
DK1621633T3 (da) 2014-05-19
KR20070058018A (ko) 2007-06-07
EP1263968A1 (en) 2002-12-11
DE60115863D1 (de) 2006-01-19
EP1621633B1 (en) 2014-04-16
US20070186311A1 (en) 2007-08-09

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