AT409381B - Xylosyltransferase-gen - Google Patents

Xylosyltransferase-gen Download PDF

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Publication number
AT409381B
AT409381B AT0035500A AT3552000A AT409381B AT 409381 B AT409381 B AT 409381B AT 0035500 A AT0035500 A AT 0035500A AT 3552000 A AT3552000 A AT 3552000A AT 409381 B AT409381 B AT 409381B
Authority
AT
Austria
Prior art keywords
xylosyltransferase
sequence
dna molecule
dna
plant
Prior art date
Application number
AT0035500A
Other languages
German (de)
English (en)
Other versions
ATA3552000A (de
Inventor
Richard Dipl Ing Strasser
Jan Dr Mucha
Lukas Dipl Ing Dr Mach
Friedrich Dipl Ing Dr Altmann
Iain B Dr Wilson
Herta Mag Dr Steinkellner
Original Assignee
Gloessl Josef Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3672559&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT409381(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gloessl Josef Dr filed Critical Gloessl Josef Dr
Priority to AT0035500A priority Critical patent/AT409381B/de
Priority to AU46495/01A priority patent/AU781010B2/en
Priority to PT51080141T priority patent/PT1621633E/pt
Priority to KR1020027011341A priority patent/KR100861437B1/ko
Priority to DK05108014.1T priority patent/DK1621633T3/da
Priority to KR1020107023909A priority patent/KR101185123B1/ko
Priority to JP2001563590A priority patent/JP5279976B2/ja
Priority to ES01919367.1T priority patent/ES2252208T5/es
Priority to EP05108014.1A priority patent/EP1621633B1/en
Priority to AT01919367T priority patent/ATE312931T1/de
Priority to KR1020087019207A priority patent/KR20080077296A/ko
Priority to US10/220,467 priority patent/US7205137B2/en
Priority to ES05108014.1T priority patent/ES2460672T3/es
Priority to DE60115863.6T priority patent/DE60115863T3/de
Priority to KR1020097019435A priority patent/KR20090101981A/ko
Priority to CA2402015A priority patent/CA2402015C/en
Priority to KR1020077011024A priority patent/KR100859919B1/ko
Priority to DK01919367.1T priority patent/DK1263968T4/da
Priority to PCT/EP2001/002352 priority patent/WO2001064901A1/en
Priority to EP01919367.1A priority patent/EP1263968B2/en
Publication of ATA3552000A publication Critical patent/ATA3552000A/de
Publication of AT409381B publication Critical patent/AT409381B/de
Application granted granted Critical
Priority to US11/684,898 priority patent/US20070186311A1/en
Priority to US13/428,777 priority patent/US20120331578A1/en
Priority to JP2013005404A priority patent/JP2013116113A/ja

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/02Pentosyltransferases (2.4.2)
    • C12Y204/02038Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024Alpha-mannosidase (3.2.1.24)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0105Alpha-N-acetylglucosaminidase (3.2.1.50)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052Beta-N-acetylhexosaminidase (3.2.1.52)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT0035500A 2000-03-03 2000-03-03 Xylosyltransferase-gen AT409381B (de)

Priority Applications (23)

Application Number Priority Date Filing Date Title
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen
ES05108014.1T ES2460672T3 (es) 2000-03-03 2001-03-02 Glicoproteínas producidas en plantas con una expresión suprimida de la beta 1,2-xilosiltransferasa
KR1020097019435A KR20090101981A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
KR1020027011341A KR100861437B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
DK05108014.1T DK1621633T3 (da) 2000-03-03 2001-03-02 Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase
KR1020107023909A KR101185123B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
JP2001563590A JP5279976B2 (ja) 2000-03-03 2001-03-02 アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子
ES01919367.1T ES2252208T5 (es) 2000-03-03 2001-03-02 Gen de beta 1,2 xilosil transferasa procedente de Arabidopsis
EP05108014.1A EP1621633B1 (en) 2000-03-03 2001-03-02 Glycoproteins produced in plants with suppressed expression of beta 1, 2-xylosyltransferase
AT01919367T ATE312931T1 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis
KR1020087019207A KR20080077296A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
US10/220,467 US7205137B2 (en) 2000-03-03 2001-03-02 β1,2-xylosyltransferase-gene from arabidopsis
AU46495/01A AU781010B2 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis
DE60115863.6T DE60115863T3 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis
PT51080141T PT1621633E (pt) 2000-03-03 2001-03-02 Glicoproteínas produzidas em plantas com supressão da expressão de beta 1,2-xilosiltransferase
CA2402015A CA2402015C (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis
KR1020077011024A KR100859919B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
DK01919367.1T DK1263968T4 (da) 2000-03-03 2001-03-02 Beta 1,2-xylosyltransferasegen fra arabidopsis
PCT/EP2001/002352 WO2001064901A1 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis
EP01919367.1A EP1263968B2 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis
US11/684,898 US20070186311A1 (en) 2000-03-03 2007-03-12 BETA 1,2-xylosyltransferase-gene from arabidopsis
US13/428,777 US20120331578A1 (en) 2000-03-03 2012-03-23 Method for Producing Recombinant Glycoproteins Having Beta1,2-Bound Xylose Residues
JP2013005404A JP2013116113A (ja) 2000-03-03 2013-01-16 アラビドプシス由来β1,2−キシロシルトランスフェラーゼ遺伝子

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen

Publications (2)

Publication Number Publication Date
ATA3552000A ATA3552000A (de) 2001-12-15
AT409381B true AT409381B (de) 2002-07-25

Family

ID=3672559

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen
AT01919367T ATE312931T1 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT01919367T ATE312931T1 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis

Country Status (12)

Country Link
US (3) US7205137B2 (https=)
EP (2) EP1621633B1 (https=)
JP (2) JP5279976B2 (https=)
KR (5) KR100861437B1 (https=)
AT (2) AT409381B (https=)
AU (1) AU781010B2 (https=)
CA (1) CA2402015C (https=)
DE (1) DE60115863T3 (https=)
DK (2) DK1621633T3 (https=)
ES (2) ES2252208T5 (https=)
PT (1) PT1621633E (https=)
WO (1) WO2001064901A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1137789T3 (da) 1998-12-09 2010-11-08 Phyton Holdings Llc Fremgangsmåde til fremstilling af et glycoprotein med glycosylering af human type
DE60044858D1 (de) 1999-10-26 2010-09-30 Stichting Dienst Landbouwkundi Säugetierartige Glykosylierung in Pflanzen
DK1356068T3 (en) 2001-01-19 2015-02-16 Phyton Holdings Llc PROCESS FOR THE PRODUCTION OF secretory glycoprotein with HUMAN TYPE SUGAR CHAIN ​​FOR USING A PLANT CELL
CN101613705A (zh) 2002-03-19 2009-12-30 国际植物研究所 在植物中优化聚糖生成
CN1665934B (zh) 2002-03-19 2010-05-26 国际植物研究所 GNTIII(UDP-N乙酰葡萄糖胺:β-D-甘露糖苷β(1,4)-N-乙酰葡萄糖胺基-转移酶III)在植物中的表达
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
EP1510584B1 (en) 2003-08-11 2009-03-18 Greenovation Biotech GmbH Expression promoting sequences from mosses and their uses
JP2009526520A (ja) * 2006-01-17 2009-07-23 バイオレックス セラピュティックス インク 植物中でのn−グリカンのヒト化及び最適化のための組成物及び方法
US20090060921A1 (en) * 2006-01-17 2009-03-05 Biolex Therapeutics, Inc. Glycan-optimized anti-cd20 antibodies
CA2646583A1 (en) * 2006-03-23 2007-09-27 Bayer Bioscience N.V. Novel nucleotide sequences encoding nicotiana beta-1,2-xylosyltransferase
WO2008125972A2 (en) 2007-04-17 2008-10-23 Plant Research International B.V. Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
RU2485180C2 (ru) 2007-06-07 2013-06-20 Эгрикалча Энд Эгри-Фуд Кэнэда Способ трансфекции и трансдукции растительных клеток
EP2789686A1 (en) 2013-04-11 2014-10-15 Greenovation Biotech GmbH Expression of phosphorylated glycoproteins in plants
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
EP3871687A1 (en) 2020-02-27 2021-09-01 eleva GmbH Enzyme replacement therapy for treating pompe disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029835A1 (en) * 1997-12-08 1999-06-17 Board Of Trustees Of The University Of Arkansas PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF

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DE69631540T2 (de) * 1995-11-23 2005-01-27 Cancer Research Technology Ltd. Materialien und methoden mit bezug zur identifizierung und sequenzierung des krebs-suszeptilitaetsgens brca2 und dessen anwendungen
DE19754622A1 (de) 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
WO1999032623A1 (en) * 1997-12-19 1999-07-01 Pharmacia & Upjohn Company Human sel-10 polypeptides and polynucleotides that encode them
US6207811B1 (en) * 1998-03-18 2001-03-27 Karl Tryggvason Nephrin gene and protein
EP1105479B1 (en) * 1998-08-11 2011-01-12 Darwin Discovery Limited Identification of the gene causing the mouse scurfy phenotype and its human ortholog
EP1033405A3 (en) * 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
BR0014945A (pt) * 1999-10-21 2004-08-31 Monsanto Co Modificação pós-traducional de proteìnas recombinantes produzidas em plantas

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029835A1 (en) * 1997-12-08 1999-06-17 Board Of Trustees Of The University Of Arkansas PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF

Non-Patent Citations (1)

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Also Published As

Publication number Publication date
CA2402015C (en) 2012-07-17
AU4649501A (en) 2001-09-12
US20120331578A1 (en) 2012-12-27
DE60115863T2 (de) 2006-08-10
DK1263968T4 (da) 2014-11-03
JP2013116113A (ja) 2013-06-13
US20040121325A1 (en) 2004-06-24
EP1621633A2 (en) 2006-02-01
KR20090101981A (ko) 2009-09-29
CA2402015A1 (en) 2001-09-07
ES2460672T3 (es) 2014-05-14
ATE312931T1 (de) 2005-12-15
DE60115863T3 (de) 2015-01-22
WO2001064901A1 (en) 2001-09-07
EP1263968B2 (en) 2014-09-10
KR20080077296A (ko) 2008-08-21
ES2252208T3 (es) 2006-05-16
KR100861437B1 (ko) 2008-10-02
AU781010B2 (en) 2005-04-28
KR20100119005A (ko) 2010-11-08
JP5279976B2 (ja) 2013-09-04
DK1263968T3 (da) 2006-05-01
JP2004500096A (ja) 2004-01-08
KR101185123B1 (ko) 2012-09-21
KR20030030987A (ko) 2003-04-18
EP1621633A3 (en) 2006-02-08
EP1263968B1 (en) 2005-12-14
US7205137B2 (en) 2007-04-17
PT1621633E (pt) 2014-07-18
KR100859919B1 (ko) 2008-09-23
ATA3552000A (de) 2001-12-15
ES2252208T5 (es) 2014-11-04
DK1621633T3 (da) 2014-05-19
KR20070058018A (ko) 2007-06-07
EP1263968A1 (en) 2002-12-11
DE60115863D1 (de) 2006-01-19
EP1621633B1 (en) 2014-04-16
US20070186311A1 (en) 2007-08-09

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