MXPA01008372A - Gen de fucosil transferasa. - Google Patents

Gen de fucosil transferasa.

Info

Publication number
MXPA01008372A
MXPA01008372A MXPA01008372A MXPA01008372A MXPA01008372A MX PA01008372 A MXPA01008372 A MX PA01008372A MX PA01008372 A MXPA01008372 A MX PA01008372A MX PA01008372 A MXPA01008372 A MX PA01008372A MX PA01008372 A MXPA01008372 A MX PA01008372A
Authority
MX
Mexico
Prior art keywords
sequence
mentioned
fucosyl transferase
transferase gene
base pair
Prior art date
Application number
MXPA01008372A
Other languages
English (en)
Inventor
Friedrich Altmann
Original Assignee
Friedrich Altmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3486087&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA01008372(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Friedrich Altmann filed Critical Friedrich Altmann
Publication of MXPA01008372A publication Critical patent/MXPA01008372A/es

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    • CCHEMISTRY; METALLURGY
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    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
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    • C12P21/00Preparation of peptides or proteins
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    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pulmonology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion proporciona una molecula de ADN la cual comprende una secuencia de conformidad con la SEC ID NO: 1 que tiene un marco de lectura abierta desde el par base 211 hasta el par base 1740 o que tiene al menos una homologia del 50% con la secuencia indicada anteriormente, o se hibridiza con la secuencia indicada anteriormente bajo condiciones severas, o que comprende una secuencia la cual se ha degenerado a la secuencia de ADN indicada anteriormente a causa del codigo genetico. La secuencia codifica una proteina vegetal que tiene una actividad de la fucosiltransferasa o es complementaria con la misma.
MXPA01008372A 1999-02-18 2000-02-17 Gen de fucosil transferasa. MXPA01008372A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0027099A AT408446B (de) 1999-02-18 1999-02-18 Fucosyltransferase-gen
PCT/AT2000/000040 WO2000049153A1 (de) 1999-02-18 2000-02-17 Fucosyltransferase-gen

Publications (1)

Publication Number Publication Date
MXPA01008372A true MXPA01008372A (es) 2003-06-06

Family

ID=3486087

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01008372A MXPA01008372A (es) 1999-02-18 2000-02-17 Gen de fucosil transferasa.

Country Status (29)

Country Link
US (3) US20080234471A1 (es)
EP (3) EP1642979A1 (es)
JP (2) JP5514386B2 (es)
KR (1) KR20010108234A (es)
CN (1) CN1360633A (es)
AT (2) AT408446B (es)
AU (1) AU771995B2 (es)
BG (1) BG65140B1 (es)
BR (1) BR0010114A (es)
CA (1) CA2362964C (es)
CZ (2) CZ308081B6 (es)
DE (1) DE50011116D1 (es)
DK (2) DK2062977T3 (es)
EE (1) EE200100432A (es)
ES (2) ES2246222T3 (es)
HR (1) HRP20010681A2 (es)
HU (1) HU230075B1 (es)
IL (2) IL144777A0 (es)
IS (1) IS6041A (es)
MX (1) MXPA01008372A (es)
NO (1) NO20013993L (es)
NZ (1) NZ513685A (es)
PL (2) PL205785B1 (es)
PT (1) PT2062977E (es)
SK (1) SK286416B6 (es)
TR (1) TR200102393T2 (es)
WO (1) WO2000049153A1 (es)
YU (1) YU58901A (es)
ZA (1) ZA200106735B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU771908C (en) 1998-12-09 2005-03-10 Phyton Holdings, Llc A method for manufacturing glycoproteins having human-type glycosylation
AT408446B (de) * 1999-02-18 2001-11-26 Altmann Friedrich Dr Fucosyltransferase-gen
ES2571230T3 (es) 1999-04-09 2016-05-24 Kyowa Hakko Kirin Co Ltd Procedimiento para controlar la actividad de una molécula inmunofuncional
IL149271A0 (en) 1999-10-26 2002-11-10 Plant Res Int Bv Mammalian-type glycosylation in plants
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
ZA200306406B (en) 2001-01-19 2004-09-06 Dow Chemical Co Method for secretory production of glycoprotein having human-type sugar chain using plant cell.
NZ534881A (en) 2002-03-19 2006-09-29 Plant Res Internat B Mammalian GnTIII expression in plants
KR101196023B1 (ko) 2002-03-19 2012-10-30 스티칭 디엔스트 랜드보위쿤디그 온데조에크 식물에서 글리칸 프로세싱의 최적화
AU2003236020B2 (en) * 2002-04-09 2009-03-19 Kyowa Hakko Kirin Co., Ltd. Cell with depression or deletion of the activity of protein participating in GDP-fucose transport
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
EP1510584B1 (en) 2003-08-11 2009-03-18 Greenovation Biotech GmbH Expression promoting sequences from mosses and their uses
FI20055398A0 (fi) 2005-07-08 2005-07-08 Suomen Punainen Risti Veripalv Menetelmä solupopulaatioiden evaluoimiseksi
AU2007205935B2 (en) 2006-01-17 2013-07-11 Synthon Biopharmaceuticals B.V. Compositions and methods for humanization and optimization of N-glycans in plants
US20090060921A1 (en) * 2006-01-17 2009-03-05 Biolex Therapeutics, Inc. Glycan-optimized anti-cd20 antibodies
CN102094020B (zh) * 2007-01-15 2012-11-28 燕秋 用于抑制LeY糖抗原合成的岩藻糖基转移酶I的RNA干涉序列及重组干涉质粒
CN102094019B (zh) * 2007-01-15 2012-11-28 燕秋 用于抑制LeY糖抗原合成的岩藻糖基转移酶Ⅳ的RNA干涉序列及重组干涉质粒
AU2008237632B2 (en) 2007-04-17 2014-01-16 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
JP5766947B2 (ja) * 2007-09-07 2015-08-19 チルドレンズ ホスピタル メディカル センター 臨床サンプルにおける分泌性のルイス抗原およびシアル化抗原のレベルの疾患リスクの予測指標としての使用
US20100242128A1 (en) * 2007-10-31 2010-09-23 Bayer BioSceince NV Method to produce modified plants with altered n-glycosylation pattern
EP2166085A1 (en) 2008-07-16 2010-03-24 Suomen Punainen Risti Veripalvelu Divalent modified cells
ES2663627T3 (es) 2010-10-11 2018-04-16 Jennewein Biotechnologie Gmbh Fucosiltransferasas novedosas y sus aplicaciones
KR101293658B1 (ko) * 2010-12-30 2013-08-07 대한민국 알파-1,3-푸코실트랜스퍼라아제 및/또는 베타-1,2-자일로실트렌스퍼라아제 유전자를 포함하는 벼 형질전환용 벡터 및 형질전환된 벼
ES2439507T3 (es) * 2011-01-20 2014-01-23 Jennewein Biotechnologie Gmbh Fucosiltransferasas novedosas y sus aplicaciones
EP2789686A1 (en) 2013-04-11 2014-10-15 Greenovation Biotech GmbH Expression of phosphorylated glycoproteins in plants
EP3050973A1 (en) * 2015-01-30 2016-08-03 Jennewein Biotechnologie GmbH Fermentation process for producing monosaccharides in free form from nucleotide-activated sugars
CN110317799A (zh) * 2019-07-18 2019-10-11 江南大学 一种人源岩藻糖转移酶8的原核表达方法及其产品
EP3871687A1 (en) 2020-02-27 2021-09-01 eleva GmbH Enzyme replacement therapy for treating pompe disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272066A (en) 1986-03-07 1993-12-21 Massachusetts Institute Of Technology Synthetic method for enhancing glycoprotein stability
JP3756946B2 (ja) 1993-03-29 2006-03-22 協和醗酵工業株式会社 α1,3−フコシルトランスフェラーゼ
US6509149B2 (en) * 1995-06-06 2003-01-21 Hybridon, Inc. HPV-specific oligonucleotides
US5770420A (en) * 1995-09-08 1998-06-23 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
AT408446B (de) * 1999-02-18 2001-11-26 Altmann Friedrich Dr Fucosyltransferase-gen

Also Published As

Publication number Publication date
US8895806B2 (en) 2014-11-25
EP2062977A1 (de) 2009-05-27
EP1642979A1 (de) 2006-04-05
DK2062977T3 (da) 2014-04-07
CZ299622B6 (cs) 2008-09-24
IL144777A (en) 2007-12-03
NO20013993D0 (no) 2001-08-16
EP2062977B1 (de) 2014-01-08
PL363438A1 (en) 2004-11-15
HRP20010681A2 (en) 2003-08-31
WO2000049153A1 (de) 2000-08-24
AU2646000A (en) 2000-09-04
NO20013993L (no) 2001-10-17
AU771995B2 (en) 2004-04-08
JP2002536978A (ja) 2002-11-05
US20130212740A1 (en) 2013-08-15
CA2362964C (en) 2012-03-27
JP5514386B2 (ja) 2014-06-04
BG65140B1 (bg) 2007-03-30
IS6041A (is) 2001-08-08
EE200100432A (et) 2002-12-16
PL205785B1 (pl) 2010-05-31
BR0010114A (pt) 2002-06-04
KR20010108234A (ko) 2001-12-07
HUP0200394A3 (en) 2006-06-28
IL144777A0 (en) 2002-06-30
SK286416B6 (sk) 2008-09-05
AT408446B (de) 2001-11-26
JP2011120592A (ja) 2011-06-23
US8198078B2 (en) 2012-06-12
BG105899A (en) 2002-12-29
EP1151109B1 (de) 2005-09-07
ES2444126T3 (es) 2014-02-24
DK1151109T3 (da) 2006-01-16
ATE304053T1 (de) 2005-09-15
CZ308081B6 (cs) 2019-12-27
US20080234471A1 (en) 2008-09-25
PT2062977E (pt) 2014-04-07
CA2362964A1 (en) 2000-08-24
DE50011116D1 (en) 2005-10-13
EP1151109A1 (de) 2001-11-07
ES2246222T3 (es) 2006-02-16
HU230075B1 (hu) 2015-06-29
YU58901A (sh) 2004-03-12
HUP0200394A2 (hu) 2002-05-29
CZ20012943A3 (cs) 2002-04-17
NZ513685A (en) 2001-09-28
US20090199306A1 (en) 2009-08-06
CN1360633A (zh) 2002-07-24
SK11182001A3 (sk) 2002-01-07
ZA200106735B (en) 2002-08-15
ATA27099A (de) 2001-04-15
PL205710B1 (pl) 2010-05-31
TR200102393T2 (tr) 2002-04-22

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