JP2002521070A5 - - Google Patents
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- Publication number
- JP2002521070A5 JP2002521070A5 JP2000562561A JP2000562561A JP2002521070A5 JP 2002521070 A5 JP2002521070 A5 JP 2002521070A5 JP 2000562561 A JP2000562561 A JP 2000562561A JP 2000562561 A JP2000562561 A JP 2000562561A JP 2002521070 A5 JP2002521070 A5 JP 2002521070A5
- Authority
- JP
- Japan
- Prior art keywords
- probe
- region
- rna polymerase
- promoter sequence
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000523 sample Substances 0.000 description 33
- 239000002773 nucleotide Substances 0.000 description 14
- 238000000034 method Methods 0.000 description 13
- 125000003729 nucleotide group Chemical group 0.000 description 12
- 150000007523 nucleic acids Chemical group 0.000 description 9
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 description 6
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 description 6
- 108091028043 Nucleic acid sequence Proteins 0.000 description 6
- 108091034117 Oligonucleotide Proteins 0.000 description 6
- 230000003321 amplification Effects 0.000 description 6
- 238000003199 nucleic acid amplification method Methods 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 108010065868 RNA polymerase SP6 Proteins 0.000 description 3
- 101710137500 T7 RNA polymerase Proteins 0.000 description 3
- 108010028263 bacteriophage T3 RNA polymerase Proteins 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- KQLDDLUWUFBQHP-UHFFFAOYSA-N Cordycepin Natural products C1=NC=2C(N)=NC=NC=2N1C1OCC(CO)C1O KQLDDLUWUFBQHP-UHFFFAOYSA-N 0.000 description 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-N Thiophosphoric acid Chemical class OP(O)(S)=O RYYWUUFWQRZTIU-UHFFFAOYSA-N 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- OFEZSBMBBKLLBJ-BAJZRUMYSA-N cordycepin Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)C[C@H]1O OFEZSBMBBKLLBJ-BAJZRUMYSA-N 0.000 description 1
- OFEZSBMBBKLLBJ-UHFFFAOYSA-N cordycepine Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)CC1O OFEZSBMBBKLLBJ-UHFFFAOYSA-N 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9497998P | 1998-07-31 | 1998-07-31 | |
| US60/094,979 | 1998-07-31 | ||
| PCT/US1999/017340 WO2000006779A1 (en) | 1998-07-31 | 1999-07-30 | Reversible inhibiting probes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002521070A JP2002521070A (ja) | 2002-07-16 |
| JP2002521070A5 true JP2002521070A5 (https=) | 2007-05-31 |
Family
ID=22248313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000562561A Pending JP2002521070A (ja) | 1998-07-31 | 1999-07-30 | 可逆的阻害プローブ |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6297365B1 (https=) |
| EP (1) | EP1100972B1 (https=) |
| JP (1) | JP2002521070A (https=) |
| AT (1) | ATE330031T1 (https=) |
| AU (1) | AU759915B2 (https=) |
| CA (1) | CA2336539A1 (https=) |
| DE (1) | DE69931928T2 (https=) |
| ES (1) | ES2265688T3 (https=) |
| WO (1) | WO2000006779A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10011529T1 (de) | 1998-05-01 | 2011-09-01 | Gen-Probe Incorporated | Automatisches Diagnoseanalysegerät und Verfahren |
| US8337753B2 (en) * | 1998-05-01 | 2012-12-25 | Gen-Probe Incorporated | Temperature-controlled incubator having a receptacle mixing mechanism |
| ATE330031T1 (de) * | 1998-07-31 | 2006-07-15 | Gen Probe Inc | Reversibel inhibierende sonden |
| AU2001280153A1 (en) * | 2000-08-25 | 2002-03-04 | Fujirebio Inc. | Method of protecting personal information |
| US6794141B2 (en) * | 2000-12-22 | 2004-09-21 | Arcturus Bioscience, Inc. | Nucleic acid amplification |
| WO2002072889A2 (en) * | 2001-01-12 | 2002-09-19 | Applera Corporation | Methods and compositions for microarray control |
| US6986992B2 (en) | 2001-03-30 | 2006-01-17 | Amersham Biosciences Ab | P450 single nucleotide polymorphism biochip analysis |
| EP1485503A4 (en) * | 2002-03-15 | 2005-12-28 | Arcturus Bioscience Inc | IMPROVED NUCLEIC ACID AMPLIFICATION |
| ATE551349T1 (de) * | 2005-11-30 | 2012-04-15 | Epict Technologies Corp | Methode unter verwendung von reversibel blockierten markierungsoligonukleotiden |
| US20080274458A1 (en) * | 2007-05-01 | 2008-11-06 | Latham Gary J | Nucleic acid quantitation methods |
| CA2754884C (en) | 2007-06-21 | 2013-04-30 | Gen-Probe Incorporated | Methods of concentrating an analyte |
| CA2964559C (en) | 2007-11-27 | 2020-01-14 | Bio-Rad Laboratories, Inc. | Reduced inhibition of one-step rt-pcr |
| JP5601777B2 (ja) * | 2008-02-13 | 2014-10-08 | 株式会社ジーンデザイン | 新規オリゴヌクレオチド誘導体及びそれから成るＮＦ−κＢデコイ |
| US8368882B2 (en) | 2009-01-30 | 2013-02-05 | Gen-Probe Incorporated | Systems and methods for detecting a signal and applying thermal energy to a signal transmission element |
| EP2504450B1 (en) * | 2009-11-23 | 2016-07-06 | Swift Biosciences, Inc. | Devices to extend single stranded target molecules |
| US20200123598A1 (en) * | 2017-06-20 | 2020-04-23 | Ulisse Biomed S.P.A. | Molecular fingerprinting methods to detect and genotype dna targets through polymerase chain reaction |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4720385A (en) * | 1983-03-29 | 1988-01-19 | Miles Laboratories, Inc. | Protein compositions substantially free from infectious agents |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5089386A (en) * | 1987-09-11 | 1992-02-18 | Gene-Trak Systems | Test for listeria |
| CA2013317A1 (en) | 1989-04-17 | 1990-10-17 | Fred T. Oakes | Diagnostic kit, primer composition and their use for replication or detection of nucleic acids |
| US5043272A (en) | 1989-04-27 | 1991-08-27 | Life Technologies, Incorporated | Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers |
| US5766849A (en) * | 1989-07-11 | 1998-06-16 | Gen-Probe Incorporated | Methods of amplifying nucleic acids using promoter-containing primer sequence |
| FI911152A7 (fi) | 1989-07-11 | 1991-03-07 | Gen Probe Inc | Nukleiinihapposekvenssin amplifikaatiomenetelmät |
| US5215899A (en) * | 1989-11-09 | 1993-06-01 | Miles Inc. | Nucleic acid amplification employing ligatable hairpin probe and transcription |
| US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
| HU218095B (hu) | 1990-05-01 | 2000-05-28 | Amgen Inc. | Eljárás átvitt szennyeződések csökkentésére, amplifikációs eljárásokban |
| US5811533A (en) * | 1990-06-11 | 1998-09-22 | Nexstar Pharmaceuticals, Inc. | High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF) |
| US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
| US5567583A (en) | 1991-12-16 | 1996-10-22 | Biotronics Corporation | Methods for reducing non-specific priming in DNA detection |
| JP4137996B2 (ja) * | 1992-05-06 | 2008-08-20 | ジェン−プローブ・インコーポレイテッド | 核酸配列増幅方法，組成物及びキット |
| GB9211979D0 (en) | 1992-06-05 | 1992-07-15 | Buchard Ole | Uses of nucleic acid analogues |
| US5338671A (en) * | 1992-10-07 | 1994-08-16 | Eastman Kodak Company | DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody |
| US5861273A (en) * | 1993-12-21 | 1999-01-19 | Celtrix Phamraceuticals, Inc. | Chromosomal expression of heterologous genes in bacterial cells |
| DE69524105T2 (de) * | 1994-07-15 | 2002-07-18 | Organon Teknika B.V., Boxtel | Verwendung von rna-polymerase zur verbesserung von nukeinsaeure-amplifikationsverfahren |
| GB2293238A (en) * | 1994-09-13 | 1996-03-20 | Inceltec Ltd | Primers for replication and/or amplification reactions |
| DE69638318D1 (de) * | 1995-06-07 | 2011-02-17 | Gilead Sciences Inc | Nukleinsäureliganden, die an DNA-Polymerasen binden und diese inhibieren |
| WO1998002582A2 (en) | 1996-07-16 | 1998-01-22 | Gen-Probe Incorporated | Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific t¿m? |
| ATE330031T1 (de) * | 1998-07-31 | 2006-07-15 | Gen Probe Inc | Reversibel inhibierende sonden |
| US6279365B1 (en) * | 2000-06-12 | 2001-08-28 | Shao-Chien Tseng | Cold forging forming method for three-dimensional hollow article |
-
1999
- 1999-07-30 AT AT99937681T patent/ATE330031T1/de not_active IP Right Cessation
- 1999-07-30 ES ES99937681T patent/ES2265688T3/es not_active Expired - Lifetime
- 1999-07-30 CA CA002336539A patent/CA2336539A1/en not_active Abandoned
- 1999-07-30 AU AU52467/99A patent/AU759915B2/en not_active Ceased
- 1999-07-30 US US09/365,121 patent/US6297365B1/en not_active Expired - Lifetime
- 1999-07-30 JP JP2000562561A patent/JP2002521070A/ja active Pending
- 1999-07-30 DE DE69931928T patent/DE69931928T2/de not_active Expired - Lifetime
- 1999-07-30 EP EP99937681A patent/EP1100972B1/en not_active Expired - Lifetime
- 1999-07-30 WO PCT/US1999/017340 patent/WO2000006779A1/en not_active Ceased
-
2001
- 2001-05-29 US US09/867,193 patent/US6602668B2/en not_active Expired - Fee Related
-
2003
- 2003-02-27 US US10/375,623 patent/US7122316B2/en not_active Expired - Fee Related
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