JP2001523231A - 膣ラクトバチルス薬 - Google Patents

膣ラクトバチルス薬

Info

Publication number
JP2001523231A
JP2001523231A JP54422298A JP54422298A JP2001523231A JP 2001523231 A JP2001523231 A JP 2001523231A JP 54422298 A JP54422298 A JP 54422298A JP 54422298 A JP54422298 A JP 54422298A JP 2001523231 A JP2001523231 A JP 2001523231A
Authority
JP
Japan
Prior art keywords
substrate
vaginal
strain
lactobacillus
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP54422298A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001523231A5 (enExample
Inventor
エル． クリソープ、ジェラルド
Original Assignee
ジャイネロジックス インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジャイネロジックス インコーポレイテッド filed Critical ジャイネロジックス インコーポレイテッド
Publication of JP2001523231A publication Critical patent/JP2001523231A/ja
Publication of JP2001523231A5 publication Critical patent/JP2001523231A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • AIDS & HIV (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
JP54422298A 1997-04-11 1998-04-10 膣ラクトバチルス薬 Pending JP2001523231A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/834,649 US6093394A (en) 1997-04-11 1997-04-11 Vaginal lactobacillus medicant
US08/834,649 1997-04-11
PCT/US1998/007510 WO1998046261A1 (en) 1997-04-11 1998-04-10 Vaginal lactobacillus medicant

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009230743A Division JP2010031031A (ja) 1997-04-11 2009-10-02 膣ラクトバチルス薬

Publications (2)

Publication Number Publication Date
JP2001523231A true JP2001523231A (ja) 2001-11-20
JP2001523231A5 JP2001523231A5 (enExample) 2005-11-24

Family

ID=25267456

Family Applications (2)

Application Number Title Priority Date Filing Date
JP54422298A Pending JP2001523231A (ja) 1997-04-11 1998-04-10 膣ラクトバチルス薬
JP2009230743A Pending JP2010031031A (ja) 1997-04-11 2009-10-02 膣ラクトバチルス薬

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009230743A Pending JP2010031031A (ja) 1997-04-11 2009-10-02 膣ラクトバチルス薬

Country Status (12)

Country Link
US (3) US6093394A (enExample)
EP (1) EP1011721B1 (enExample)
JP (2) JP2001523231A (enExample)
KR (1) KR20010006273A (enExample)
CN (1) CN1194758C (enExample)
AT (1) ATE400281T1 (enExample)
AU (1) AU732630B2 (enExample)
BR (1) BR9808520A (enExample)
CA (1) CA2285947C (enExample)
DE (1) DE69839699D1 (enExample)
NZ (2) NZ500788A (enExample)
WO (1) WO1998046261A1 (enExample)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005139176A (ja) * 2003-11-03 2005-06-02 Peter-Hansen Volkmann 膣ケア調合物
JP2008517014A (ja) * 2004-10-22 2008-05-22 メディノヴァ・アクチェンゲゼルシャフト 泌尿生殖器の病原体に対して有用な乳酸菌株およびそれらを含む組成物
JP2008517015A (ja) * 2004-10-22 2008-05-22 メディノバ アクチェンゲゼルシャフト 胃腸病原菌に対して有用な乳酸菌、及び当該乳酸菌を含む組成物
JP2010031031A (ja) * 1997-04-11 2010-02-12 Osel Inc 膣ラクトバチルス薬
JP2010511033A (ja) * 2006-11-28 2010-04-08 プロバイオティカル エス．ピー．エイ． 婦人科および直腸科分野における生物活性成分投与のための組成物とその使用方法
JP2015501635A (ja) * 2011-11-10 2015-01-19 ジェネラル ミルズ インコーポレーティッド 桿状菌の生存能力を高める手段及び方法
JP2017501741A (ja) * 2013-11-08 2017-01-19 スーヂョウ オーセル バイオ−ファーム カンパニー、リミテッド ラクトバチルス・クリスパタスおよびその応用
KR20180070485A (ko) * 2016-12-16 2018-06-26 (주)휴온스 안정성이 증진된 유산균 및 이의 제조방법
JP2019521134A (ja) * 2016-07-11 2019-07-25 ヘネピン・ライフ・サイエンシーズ・エルエルシーＨｅｎｎｅｐｉｎ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ，Ｌｌｃ 性感染症用組成物
JP2019531720A (ja) * 2016-09-16 2019-11-07 デュポン ニュートリション バイオサイエンシーズ エーピーエス 細菌
JP2020526583A (ja) * 2017-07-07 2020-08-31 オセル、インコーポレイテッド 高効力かつ安定な膣ラクトバチルス調製物
JP2024510109A (ja) * 2021-02-19 2024-03-06 インペリアル・カレッジ・イノベーションズ・リミテッド 妊娠中の対象に使用するためのラクトバチルス・クリスパタス組成物

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9916790D0 (en) * 1999-07-16 1999-09-22 Health Lab Service Board Storage of microorganisms,cells and tissue
SE521022C2 (sv) * 2001-09-20 2003-09-23 Ellen Ab Mjölksyraproducerande bakterier för användning som probiotiska organismer i vaginan hos människa
GB0124580D0 (en) * 2001-10-12 2001-12-05 Univ Reading New composition
US7709026B2 (en) * 2001-10-29 2010-05-04 Columbia Laboratories, Inc. Low concentration of peroxide for treating or preventing vaginal infections
US7179458B2 (en) * 2002-03-08 2007-02-20 Osel, Inc. Lactobacilli expressing biologically active polypeptides and uses thereof
PL212647B1 (pl) * 2002-03-21 2012-11-30 Bifodan As Kompozycja farmaceutyczna, szczep Lactobacillus paracasei Lbp PB01 oraz szczep Lactobacillus paracasei Lbp PB01 w polaczeniu ze szczepem Lactobacillus acidophilus Lba EB01, produkt chlonny zawierajacy te kompozycje oraz produkt nabialowy, produkt nutraceutyczny i czynnosciowy produkt zywnosciowy zawierajace ten szczep albo te dwa szczepy, a takze zastosowanie tego szczepu albo tych dwóch szczepów
KR100993562B1 (ko) 2002-03-21 2010-11-11 비포단 에이/에스 락토바실러스 균주
AU2003215472A1 (en) * 2002-03-28 2003-10-13 Jeremy Burton Lactobacillus iners for the enhancement of urogenital health
JP2004067599A (ja) * 2002-08-07 2004-03-04 Kunihiko Tominaga 腟内洗浄剤
AT413334B (de) * 2002-12-23 2006-02-15 Belihart Josephine Feste darreichungsformen mit lebenden milchsäurebakterien
US20040126369A1 (en) * 2002-12-30 2004-07-01 Richard Payne Delivery of peroxide-generating enzymes to the vaginal tract
US20050095660A1 (en) * 2003-10-31 2005-05-05 Unibio, S.R.I. Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women
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WO2005085287A1 (en) * 2004-03-03 2005-09-15 En-N-Tech, Inc. Treatments for contaminant reduction in lactoferrin preparations and lactoferrin-containing compositions
US8247637B2 (en) * 2004-07-23 2012-08-21 Femaceuticals, Llc Mini pad for reducing inflammation of the vulva and method of making the same
SE528382C2 (sv) * 2004-10-05 2006-10-31 Probi Ab Probiotiska lactobacillusstammar för förbättrad vaginal hälsa
US7619008B2 (en) * 2004-11-12 2009-11-17 Kimberly-Clark Worldwide, Inc. Xylitol for treatment of vaginal infections
US20060217446A1 (en) * 2005-03-28 2006-09-28 Kimberly-Clark Worldwide, Inc. Method for preventing and/or treating trichomonas vaginitis
US20060106117A1 (en) * 2004-11-12 2006-05-18 Kimberly-Clark Worldwide, Inc. Compound and method for prevention and/or treatment of vaginal infections
US20060223765A1 (en) * 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Method for inhibiting and/or treating vaginal infection
US7786176B2 (en) * 2005-07-29 2010-08-31 Kimberly-Clark Worldwide, Inc. Vaginal treatment composition containing xylitol
JP2009503098A (ja) * 2005-08-04 2009-01-29 フェマシューティカルズ リミテッド ライアビリティ カンパニー おむつかぶれおよび同等物などの皮膚炎を治療するための方法
US20070082035A1 (en) 2005-10-06 2007-04-12 New York Blood Center, Inc. Anti-infective hygiene products based on cellulose acetate phthalate
WO2007073265A1 (en) 2005-12-22 2007-06-28 Sca Hygiene Products Ab Absorbent article
US8399012B2 (en) 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
US8222020B2 (en) 2006-11-17 2012-07-17 Sca Hygiene Products Ab Biologically pure strain of Lactobacillus fermentum, strain Ess-1
AU2006350772C1 (en) 2006-11-17 2013-05-23 Essity Hygiene And Health Aktiebolag Hygiene tissue comprising a microbe-inhibiting composition
EP2081606B1 (en) 2006-11-17 2015-03-18 SCA Hygiene Products AB Sanitary article comprising a microbe-inhibiting composition
US20110066137A1 (en) * 2007-12-18 2011-03-17 Osel, Inc. Applicator for applying powder formulations and uses thereof
WO2009123982A2 (en) * 2008-03-31 2009-10-08 Osel, Inc. Transiently buffered lactobacillus preparations and use thereof
ITMI20080949A1 (it) * 2008-05-22 2009-11-23 Sinclair Pharma Srl Nuovo ceppo del genere lactobacillus e formulazioni farmaceutiche topiche che lo contengono
EP2206506A1 (en) 2008-12-18 2010-07-14 Bracco Imaging S.p.A Probiotic formulations
US8445226B2 (en) * 2010-02-01 2013-05-21 Microbios, Inc. Process and composition for the manufacture of a microbial-based product
US7888062B1 (en) 2010-02-01 2011-02-15 Microbios, Inc. Process and composition for the manufacture of a microbial-based product
IL208820A0 (en) 2010-10-19 2011-01-31 Rachel Teitelbaum Biologic female contraceptives
TWI401086B (zh) * 2010-07-20 2013-07-11 Univ China Medical 胚芽乳酸桿菌及其用途
US9034593B2 (en) 2010-11-22 2015-05-19 Kimberly-Clark Worldwide, Inc. Vaginal indicator to detect biomarkers of good health
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WO2013113767A1 (en) * 2012-01-31 2013-08-08 Bioclin Bv Method for administration of a probiotic
JP6352907B2 (ja) 2012-06-13 2018-07-04 イボフェム， インコーポレイテッド 避妊殺菌剤の効果を増強するための組成物および方法
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
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CN104178437B (zh) * 2013-11-08 2016-08-24 苏州欧赛微科生物医药科技有限公司 一种卷曲乳杆菌及其在妇科疾病中的应用
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AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
CN104293718B (zh) * 2014-10-11 2017-01-18 中国科学院微生物研究所 一株詹氏乳杆菌及其应用
KR101980252B1 (ko) 2015-05-26 2019-05-21 (주)투라인스 질증 치료용 조성물
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US11166968B2 (en) 2015-09-29 2021-11-09 Kimberly-Clark Worldwide, Inc. Synergistic composition for maintenance of healthy balance of microflora
FR3048361B1 (fr) * 2016-03-01 2020-12-18 Biose Compositions pour le traitement des candidoses
KR101957211B1 (ko) * 2016-03-21 2019-03-13 한국생명공학연구원 조산 및 질염 원인균에 대한 항균 활성, 성병 원인 바이러스에 대한 항바이러스 활성 및 질내 부착능이 우수한 락토바실러스 속 균주 및 이의 용도
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JP2019531720A (ja) * 2016-09-16 2019-11-07 デュポン ニュートリション バイオサイエンシーズ エーピーエス 細菌
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KR102048690B1 (ko) 2016-12-16 2019-11-26 (주)휴온스 안정성이 증진된 유산균 및 이의 제조방법
JP2020526583A (ja) * 2017-07-07 2020-08-31 オセル、インコーポレイテッド 高効力かつ安定な膣ラクトバチルス調製物
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JP2024510109A (ja) * 2021-02-19 2024-03-06 インペリアル・カレッジ・イノベーションズ・リミテッド 妊娠中の対象に使用するためのラクトバチルス・クリスパタス組成物

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