JP2001516574A - ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム - Google Patents

４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム

Info

Publication number
JP2001516574A
JP2001516574A JP2000511853A JP2000511853A JP2001516574A JP 2001516574 A JP2001516574 A JP 2001516574A JP 2000511853 A JP2000511853 A JP 2000511853A JP 2000511853 A JP2000511853 A JP 2000511853A JP 2001516574 A JP2001516574 A JP 2001516574A
Authority
JP
Japan
Prior art keywords
coli
host
gene
coa
pha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000511853A
Other languages
English (en)
Japanese (ja)
Inventor
ギャルト ダブリュー． ハイスマン，
フランク エイ． スクラリー，
デイビッド ピー． マーティン，
オリバー ピー． ピープルズ，
Original Assignee
メタボリックス，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by メタボリックス，インコーポレイテッド filed Critical メタボリックス，インコーポレイテッド
Publication of JP2001516574A publication Critical patent/JP2001516574A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2000511853A 1997-09-19 1998-09-18 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム Withdrawn JP2001516574A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5937397P 1997-09-19 1997-09-19
US60/059,373 1997-09-19
PCT/US1998/019659 WO1999014313A2 (en) 1997-09-19 1998-09-18 Biological systems for manufacture of polyhydroxylalkanoate polymers containing 4-hydroxyacids

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2003132325A Division JP2003310262A (ja) 1997-09-19 2003-05-09 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム

Publications (1)

Publication Number Publication Date
JP2001516574A true JP2001516574A (ja) 2001-10-02

Family

ID=22022544

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2000511853A Withdrawn JP2001516574A (ja) 1997-09-19 1998-09-18 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム
JP2003132325A Withdrawn JP2003310262A (ja) 1997-09-19 2003-05-09 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム
JP2008328226A Pending JP2009082147A (ja) 1997-09-19 2008-12-24 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム
JP2008328227A Pending JP2009171960A (ja) 1997-09-19 2008-12-24 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2003132325A Withdrawn JP2003310262A (ja) 1997-09-19 2003-05-09 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム
JP2008328226A Pending JP2009082147A (ja) 1997-09-19 2008-12-24 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム
JP2008328227A Pending JP2009171960A (ja) 1997-09-19 2008-12-24 ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム

Country Status (8)

Country Link
US (6) US6316262B1 (enExample)
EP (1) EP1015565B1 (enExample)
JP (4) JP2001516574A (enExample)
AT (1) ATE323152T1 (enExample)
AU (1) AU725516B2 (enExample)
CA (1) CA2303070C (enExample)
DE (2) DE69838768T2 (enExample)
WO (1) WO1999014313A2 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004065609A1 (ja) 2003-01-22 2004-08-05 Showa Denko K.K. アシルコエンザイムａを用いるアシル基転移酵素反応方法
JP2006000091A (ja) * 2004-05-20 2006-01-05 Mitsubishi Chemicals Corp オキザロ酢酸またはオキザロ酢酸誘導体の製造方法
JP2012511912A (ja) * 2008-12-12 2012-05-31 メタボリックス，インコーポレイテッド ポリ（５ｈｖ）および５炭素化合物を製造するための環境に優しい方法および組成物
WO2013035372A1 (ja) * 2011-09-05 2013-03-14 独立行政法人理化学研究所 長主鎖構造を有するポリヒドロキシアルカン酸の製造方法
JP2019503188A (ja) * 2016-01-28 2019-02-07 コリア アドバンスト インスティチュート オブ サイエンス アンド テクノロジー キシロースからポリ（ラクテート‐ｃｏ‐グリコレート）またはその共重合体生産能を有する組換え微生物、およびそれを用いたポリ（ラクテート‐ｃｏ‐グリコレート）またはその共重合体の製造方法
JPWO2020179613A1 (enExample) * 2019-03-06 2020-09-10

Families Citing this family (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7455999B2 (en) * 1998-01-22 2008-11-25 Metabolix, Inc. Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate)
ATE483023T1 (de) 1998-05-22 2010-10-15 Metabolix Inc Polyhydroxyalkanoatbiopolymere
EP1105514B1 (en) 1998-08-04 2008-02-06 Metabolix, Inc. Polyhydroxyalkanoate production from polyols
WO2000011188A1 (en) 1998-08-18 2000-03-02 Metabolix, Inc. Transgenic microbial polyhydroxyalkanoate producers
EP1700908B1 (en) * 1998-08-18 2016-01-06 Metabolix, Inc. Transgenic microbial polyhydroxyalkanoate producers
DE60036863T2 (de) 1999-03-25 2008-07-31 Metabolix, Inc., Cambridge Medizinische vorrichtungen und verwendungen von polyhydroxyalkanoatpolymeren
AU783104B2 (en) 1999-09-14 2005-09-22 Tepha, Inc. Therapeutic uses of polymers and oligomers comprising gamma-hydroxybutyrate
EP1255846B1 (en) 2000-02-11 2010-01-06 Metabolix, Inc. Multi-gene expression constructs containing modified inteins
KR20040014389A (ko) 2000-07-21 2004-02-14 메타볼릭스 인코포레이티드 폴리올로부터 폴리하이드록시알칸노에이트를 제조하는 방법
US6897338B2 (en) 2001-12-18 2005-05-24 Metabolix, Inc. Methods of making intermediates from polyhydroxyalkanoates
US7318833B2 (en) 2001-12-19 2008-01-15 Nmt Medical, Inc. PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
EP1467661A4 (en) 2001-12-19 2008-11-05 Nmt Medical Inc SEPTAL SHUTTER AND ASSOCIATED METHODS
US7220265B2 (en) * 2002-01-14 2007-05-22 Nmt Medical, Inc. Patent foramen ovale (PFO) closure method and device
EP1487353A4 (en) 2002-03-25 2008-04-16 Nmt Medical Inc FORAMEN OVAL PERSISTENT CLOSURE CLAMPS (PFO)
EP1538994A4 (en) 2002-06-05 2008-05-07 Nmt Medical Inc DEVICE FOR CLOSING A PATENT FORAMS OVALE (PFO) WITH RADIAL AND COMPLEMENTARY SUPPORT
AUPS318202A0 (en) * 2002-06-26 2002-07-18 Cochlear Limited Parametric fitting of a cochlear implant
ATE505559T1 (de) 2002-09-12 2011-04-15 Metabolix Inc Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege
US7766820B2 (en) 2002-10-25 2010-08-03 Nmt Medical, Inc. Expandable sheath tubing
AU2003287554A1 (en) * 2002-11-06 2004-06-03 Nmt Medical, Inc. Medical devices utilizing modified shape memory alloy
AU2003294682A1 (en) 2002-12-09 2004-06-30 Nmt Medical, Inc. Septal closure devices
EP1638615B1 (en) 2003-05-08 2014-10-29 Tepha, Inc. Polyhydroxyalkanoate medical textiles and fibers
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
JP4917887B2 (ja) 2003-07-14 2012-04-18 ダブリュー．エル．ゴア アンド アソシエイツ，インコーポレイテッド 捕捉システムを有する管状の卵円孔開存（ｐｆｏ）閉鎖デバイス
US8480706B2 (en) 2003-07-14 2013-07-09 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
DE602004017750D1 (de) 2003-08-19 2008-12-24 Nmt Medical Inc Expandierbarer Schleusenschlauch
US7579176B2 (en) * 2003-10-15 2009-08-25 Newlight Technologies, Llc Method for the production of polyhydroxyalkanoic acid
US8735113B2 (en) 2003-10-15 2014-05-27 Newlight Technologies, Llc Methods and systems for production of polyhydroxyalkanoate
US7745197B1 (en) 2003-10-15 2010-06-29 Newlight Technologies, Llc Process for the utilization of ruminant animal methane emissions
US20050273119A1 (en) * 2003-12-09 2005-12-08 Nmt Medical, Inc. Double spiral patent foramen ovale closure clamp
US7871419B2 (en) 2004-03-03 2011-01-18 Nmt Medical, Inc. Delivery/recovery system for septal occluder
US20050267524A1 (en) 2004-04-09 2005-12-01 Nmt Medical, Inc. Split ends closure device
US8361110B2 (en) 2004-04-26 2013-01-29 W.L. Gore & Associates, Inc. Heart-shaped PFO closure device
US7842053B2 (en) 2004-05-06 2010-11-30 Nmt Medical, Inc. Double coil occluder
US8308760B2 (en) 2004-05-06 2012-11-13 W.L. Gore & Associates, Inc. Delivery systems and methods for PFO closure device with two anchors
US8257389B2 (en) 2004-05-07 2012-09-04 W.L. Gore & Associates, Inc. Catching mechanisms for tubular septal occluder
ES2362217T3 (es) 2004-08-03 2011-06-29 Tepha, Inc. Suturas de polihidroxialcanoato no rizadas.
CA2581677C (en) 2004-09-24 2014-07-29 Nmt Medical, Inc. Occluder device double securement system for delivery/recovery of such occluder device
WO2006101983A2 (en) 2005-03-16 2006-09-28 Metabolix, Inc. Chemically inducible expression of biosynthetic pathways
US8277480B2 (en) 2005-03-18 2012-10-02 W.L. Gore & Associates, Inc. Catch member for PFO occluder
KR100979694B1 (ko) 2005-05-24 2010-09-02 한국과학기술원 폴리락테이트 또는 그 공중합체 생성능을 가지는 세포 또는식물 및 이를 이용한 폴리락테이트 또는 그 공중합체의제조방법
DK2781593T3 (da) * 2005-08-22 2019-10-21 Newlight Tech Inc Fremgangsmåde til behandling af methanemissioner
CA2627285A1 (en) * 2005-10-24 2007-10-25 Nmt Medical, Inc. Radiopaque bioabsorbable occluder
EP1962695A1 (en) 2005-12-22 2008-09-03 NMT Medical, Inc. Catch members for occluder devices
ES2395076T3 (es) * 2006-02-07 2013-02-08 Tepha, Inc. Stents y revestimientos degradables poliméricos liberadores de fármacos
WO2007092464A2 (en) * 2006-02-07 2007-08-16 Tepha, Inc. Methods and devices for rotator cuff repair
US8979921B2 (en) * 2006-02-07 2015-03-17 Tepha, Inc. Polymeric, degradable drug-eluting stents and coatings
US9592325B2 (en) * 2006-02-07 2017-03-14 Tepha, Inc. Polymeric, degradable drug-eluting stents and coatings
US8870913B2 (en) 2006-03-31 2014-10-28 W.L. Gore & Associates, Inc. Catch system with locking cap for patent foramen ovale (PFO) occluder
US8551135B2 (en) 2006-03-31 2013-10-08 W.L. Gore & Associates, Inc. Screw catch mechanism for PFO occluder and method of use
JP2009532125A (ja) 2006-03-31 2009-09-10 エヌエムティー メディカル， インコーポレイティッド オクルーダ装置用の変形可能なフラップキャッチ機構
US9089627B2 (en) 2006-07-11 2015-07-28 Abbott Cardiovascular Systems Inc. Stent fabricated from polymer composite toughened by a dispersed phase
JP5468779B2 (ja) * 2006-07-21 2014-04-09 株式会社カネカ 遺伝子置換微生物およびそれを用いたポリエステルの製造方法
US20080082083A1 (en) * 2006-09-28 2008-04-03 Forde Sean T Perforated expandable implant recovery sheath
JP5565938B2 (ja) * 2006-11-21 2014-08-06 エルジー・ケム・リミテッド ４−ヒドロキシブチレート単位とラクテート単位を含有する共重合体及びその製造方法
US7943683B2 (en) 2006-12-01 2011-05-17 Tepha, Inc. Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers
JP2010517638A (ja) * 2007-02-02 2010-05-27 トアニエ， インコーポレイテッド 腱および靱帯を修復するシステムおよび方法
TWI568847B (zh) * 2007-03-16 2017-02-01 奇諾麥提卡公司 用於１，４-丁二醇及其前驅物之生物合成的組合物及方法
WO2008124603A1 (en) 2007-04-05 2008-10-16 Nmt Medical, Inc. Septal closure device with centering mechanism
US9138562B2 (en) 2007-04-18 2015-09-22 W.L. Gore & Associates, Inc. Flexible catheter system
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
US8581041B2 (en) 2007-08-30 2013-11-12 Plant Sensory Systems, Llc Methods of producing GABA
WO2009032755A2 (en) * 2007-08-30 2009-03-12 Plant Sensory System, Llc. Alternative methods for the biosynthesis of gaba
US8581040B2 (en) 2007-08-30 2013-11-12 Plant Sensory Systems, Llc Methods of producing GABA
TWI356705B (en) * 2007-10-25 2012-01-21 Internat Chlorella Co Ltd Extracts from chlorella sorokiniana
WO2009078973A2 (en) * 2007-12-13 2009-06-25 Glycos Biotechnologies, Incorporated Microbial conversion of oils and fatty acids to high-value chemicals
US8287909B2 (en) * 2007-12-19 2012-10-16 Tepha, Inc. Medical devices containing melt-blown non-wovens of poly-4-hydroxybutyrate and copolymers thereof
KR20090078925A (ko) * 2008-01-16 2009-07-21 주식회사 엘지화학 폴리락테이트 또는 그 공중합체 생성능을 가지는 재조합미생물 및 이를 이용한 폴리락테이트 또는 그 공중합체의제조방법
US20130165967A1 (en) 2008-03-07 2013-06-27 W.L. Gore & Associates, Inc. Heart occlusion devices
US20090253154A1 (en) * 2008-04-02 2009-10-08 Immunosciences Lab., Inc. Blood and saliva test for detection of delayed food allergy and intolerance against modified foods
US8487159B2 (en) * 2008-04-28 2013-07-16 Metabolix, Inc. Production of polyhydroxybutyrate in switchgrass
US20110190513A1 (en) * 2008-07-08 2011-08-04 Lynch Michael D Methods, compositions and systems for biosynthetic bio-production of 1,4-butanediol
CA2735883C (en) 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
EP2397545B1 (en) * 2009-02-10 2015-07-29 Kyowa Hakko Bio Co., Ltd. Method for producing amino acid
AU2010221135A1 (en) * 2009-03-05 2011-09-29 Metabolix, Inc. Propagation of transgenic plants
KR20180042467A (ko) 2009-06-04 2018-04-25 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
US8129169B2 (en) 2009-06-04 2012-03-06 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
US20120029556A1 (en) 2009-06-22 2012-02-02 Masters Steven J Sealing device and delivery system
US9636094B2 (en) 2009-06-22 2017-05-02 W. L. Gore & Associates, Inc. Sealing device and delivery system
WO2011031566A1 (en) 2009-08-27 2011-03-17 Newlight Technologies, Llc Process for the production of polyhydroxyalkanoates
EP2477477A1 (en) 2009-09-15 2012-07-25 Metabolix, Inc. Generation of high polyhydroxybutrate producing oilseeds
WO2011047101A1 (en) 2009-10-13 2011-04-21 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
US20110125118A1 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an Organic Acid and/or Related Chemicals
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
WO2011068952A1 (en) 2009-12-02 2011-06-09 Entrigue Surgical, Inc. Devices for tongue stabilization
CN102781901B (zh) 2010-02-11 2016-08-03 梅塔玻利克斯公司 用于从经遗传修饰的聚羟基链烷酸酯生物质制备单体组分的方法
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
GB2478588A (en) * 2010-03-12 2011-09-14 G5 Internat Holdings Pte Ltd Microbial production of polyhydroxyalkanoates (PHAs) using culture medium containing hydrogen
PT2558133T (pt) 2010-03-26 2020-04-23 Tepha Inc Revestimentos para o fabrico e aplicação de dispositivos médicos de polihidroxialcanqato
US9511169B2 (en) 2010-06-15 2016-12-06 Tepha, Inc. Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers with anisotropic properties
WO2011159784A1 (en) 2010-06-15 2011-12-22 Tepha, Inc. Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers
EP2425865A1 (en) 2010-08-06 2012-03-07 Aesculap AG Medicinal thread having a polyhydroxyalkanoate coating
US20120060413A1 (en) 2010-09-15 2012-03-15 Metabolix, Inc. Increasing carbon flow for polyhydroxybutyrate production in biomass crops
EP2637734B1 (en) 2010-11-09 2017-09-13 Tepha, Inc. Drug eluting cochlear implants
US8956835B2 (en) 2010-11-24 2015-02-17 Suny Research Foundation Methods for producing polyhydroxyalkanoates from biodiesel-glycerol
CA2825624C (en) 2011-01-27 2020-01-14 Osa Holdings, Inc. Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
WO2012122343A2 (en) 2011-03-08 2012-09-13 Newlight Technologies, Llc Polyhydroxyalkanoate production method
WO2012149407A1 (en) 2011-04-29 2012-11-01 Metabolix, Inc. Process for latex production by melt emulsification
WO2012149162A2 (en) * 2011-04-29 2012-11-01 Metabolix, Inc. Green process for producing polyhydroxyalkanoates and chemicals using a renewable feedstock
WO2012170793A1 (en) 2011-06-08 2012-12-13 Metabolix, Inc. Biorefinery process for thf production
US9822387B2 (en) 2011-07-29 2017-11-21 Mitsui Chemicals, Inc. Microorganism having carbon dioxide fixation pathway introduced thereinto
US20140170714A1 (en) 2011-08-10 2014-06-19 Metabolix, Inc. Post process purification for gamma-butyrolactone production
US9770232B2 (en) 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
ES2659525T3 (es) 2011-09-27 2018-03-16 Tepha, Inc. Hidrólisis controlada de poli-4-hidroxibutirato y copolímeros
JP6199872B2 (ja) 2011-10-25 2017-09-20 マローネ バイオ イノベーションズ，インコーポレイテッド クロモバクテリウム（Ｃｈｒｏｍｏｂａｃｔｅｒｉｕｍ）配合物、組成物、代謝産物、およびそれらの使用
EP2773767A4 (en) 2011-11-02 2015-08-05 Genomatica Inc MICROORGANISMS AND METHOD FOR THE PRODUCTION OF CAPROLACTONE
US12060597B2 (en) 2011-12-02 2024-08-13 Newlight Technologies, Inc. Polyhydroxyalkanoate production methods and systems for same
US20200347417A1 (en) 2012-03-29 2020-11-05 Newlight Technologies, Inc Polyhydroxyalkanoate production methods and materials and microorganisms used in same
US9085784B1 (en) 2012-03-29 2015-07-21 Newlight Technologies, Llc Polyhydroxyalkanoate production methods and materials and microorganisms used in same
CN104520433A (zh) * 2012-04-11 2015-04-15 赫姆霍尔兹传染病研究中心有限责任公司 产生pha的基因工程微生物
WO2013176734A1 (en) 2012-05-21 2013-11-28 Tepha, Inc. Resorbable bioceramic compositions of poly-4-hydroxybutyrate and copolymers
SI2855687T1 (sl) 2012-06-04 2020-09-30 Genomatica, Inc. Mikroorganizmi in metode za proizvodnjo 4-hidroksibutirat, 1,4-butandiola in sorodne spojine
BR112014030203B1 (pt) 2012-06-08 2021-10-13 Cj Cheiljedang Corporation Processo para produção de produtos de ácido acrílico de base biológica
WO2014028943A1 (en) 2012-08-17 2014-02-20 Metabolix, Inc. Biobased rubber modifiers for polymer blends
WO2014058655A1 (en) 2012-10-10 2014-04-17 Metabolix Polyhydroxyalkanoate copolymer compositions and methods of making the same
ES2774932T3 (es) 2012-11-14 2020-07-23 Cj Cheiljedang Corp Producción de sales de 4-hidroxibutirato utilizando materias primas de base biológica
ES2751398T3 (es) 2013-01-15 2020-03-31 Tepha Inc Implantes para regeneración de tejido blando y tejido duro
US10828019B2 (en) 2013-01-18 2020-11-10 W.L. Gore & Associates, Inc. Sealing device and delivery system
EP2949751B1 (en) 2013-01-24 2022-08-03 Mitsui Chemicals, Inc. Microorganism having carbon dioxide fixation cycle introduced thereinto
US20150376152A1 (en) 2013-02-13 2015-12-31 Metabolix, Inc. Process for Ultra Pure Chemical Production from Biobased Raw Starting Materials
US10201640B2 (en) 2013-03-13 2019-02-12 Tepha, Inc. Ultrafine electrospun fibers of poly-4-hydroxybutyrate and copolymers thereof
US9687585B2 (en) 2013-08-20 2017-06-27 Tepha, Inc. Thermoformed poly-4-hydroxybutyrate medical implants
US10689498B2 (en) 2013-08-20 2020-06-23 Tepha, Inc. Closed cell foams including poly-4-hydroxybutyrate and copolymers thereof
US9302029B2 (en) 2013-10-31 2016-04-05 Tepha, Inc. Pultrusion of poly-4-hydroxybutyrate and copolymers thereof
ES2705687T3 (es) 2013-11-05 2019-03-26 Tepha Inc Composiciones y dispositivos de poli-4-hidroxibutirato
EP3082617B1 (en) 2013-12-19 2022-11-16 Tornier, Inc. High-strength bioabsorbable suture
ES2834498T3 (es) 2013-12-26 2021-06-17 Tepha Inc Implantes médicos que incluyen laminados de poli-4-hidroxibutirato y copolímeros del mismo
WO2015143000A1 (en) 2014-03-18 2015-09-24 Tepha, Inc. Micro-fiber webs of poly-4-hydroxybutyrate and copolymers thereof produced by centrifugal spinning
WO2015167807A1 (en) 2014-04-30 2015-11-05 Tepha, Inc. Three-dimensional resorbable implants for tissue reinforcement and hernia repair
WO2016057083A2 (en) 2014-05-16 2016-04-14 Tepha, Inc. Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers with anisotropic properties
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system
CA2958747C (en) 2014-08-15 2022-08-16 Tepha, Inc. Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof
ES2661648T3 (es) 2014-08-20 2018-04-02 Tepha, Inc. Implantes médicos de poli-4-hidroxibutirato termoformados
US10525172B2 (en) 2014-09-22 2020-01-07 Tepha, Inc. Oriented P4HB implants containing antimicrobial agents
WO2016053741A1 (en) 2014-10-01 2016-04-07 Cryosa, Llc Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
US10626521B2 (en) 2014-12-11 2020-04-21 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
US9555155B2 (en) 2014-12-11 2017-01-31 Tepha, Inc. Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof
WO2017068385A1 (en) 2015-10-23 2017-04-27 Metabolic Explorer Microorganism modified for the assimilation of levulinic acid
DK3400100T3 (da) 2016-01-06 2020-10-26 Archer Daniels Midland Co Fremgangsmåde til fremstilling af 1,3-butandiol og til eventuelt yderligere fremstilling af (r)-3-hydroxybutyl (r)-3-hydroxybutyrat
CA3064729C (en) 2017-05-25 2022-03-29 Tepha, Inc. Continuous formation of tubes of poly-4-hydroxybutyrate and copolymers thereof
CN109112151B (zh) * 2017-06-23 2021-10-29 北京蓝晶微生物科技有限公司 一种精细调控共聚物中4-羟基丁酸组成比例的基因盒及其应用
WO2019050936A1 (en) 2017-09-06 2019-03-14 Tepha, Inc. CALANDERATED SURGICAL TRELLIS COMPRISING POLYHYDROXYALKANOATES
EP3720514B1 (en) 2017-12-04 2022-04-13 Tepha, Inc. Vacuum membrane thermoformed poly-4-hydroxybutyrate medical implants
US11407168B2 (en) 2018-06-11 2022-08-09 Tepha, Inc. Methods for 3D printing of poly-4-hydroxybutyrate and copolymers
EP3873546B1 (en) 2018-10-29 2023-07-12 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
WO2020142519A1 (en) 2018-12-31 2020-07-09 Cryosa, Inc. Systems and methods for treatment of obstructive sleep apnea
USD1137197S1 (en) * 2019-03-01 2026-07-28 Sonos, Inc. Media player device
AU2020293986B2 (en) 2019-06-10 2026-05-07 Nuseed Nutritional Us Inc. Transgenic land plants that express a polyhydroxyalkanoate synthase seed specifically with cytosolic localization
CA3168812A1 (en) 2020-02-19 2021-08-26 Cryosa, Inc. Systems and methods for treatment of obstructive sleep apnea
FR3109290B1 (fr) 2020-04-17 2025-04-11 Ph Tech Dispositif médical comprenant une matrice biologique acellulaire et au moins un polymère
FR3110077B1 (fr) 2020-05-12 2024-12-06 Ph Tech Procédé de fabrication d’un dispositif médical en trois dimensions et dispositif médical obtenu
FR3113371A1 (fr) 2020-08-12 2022-02-18 Ph Tech Dispositif médical comprenant un assemblage d’éléments de matrices biologiques acellulaires et au moins un polymère
JP2024510182A (ja) 2021-03-11 2024-03-06 テファ， インコーポレイテッド 乳房再建インプラント
CN113832084B (zh) * 2021-09-29 2024-01-05 北京化工大学 一种生产聚羟基脂肪酸酯的溶藻弧菌及其应用
AU2022424121A1 (en) 2021-12-30 2024-06-20 Cryosa, Inc. Systems and methods for treatment of obstructive sleep apnea
KR20250108103A (ko) * 2022-09-30 2025-07-15 킴벌리-클라크 월드와이드, 인크. 특정 사슬 길이 폴리(하이드록시알카노에이트) 단량체의 시험관 내 생합성
FR3165166A1 (fr) 2024-08-05 2026-02-06 Ph Tech Utilisation de l’Éther de dipropylène glycol monométhylique pour purifier un biomatériau

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS575693A (en) 1980-06-13 1982-01-12 Ajinomoto Co Inc Production of l-arginine through fermentation process
IE50442B1 (en) * 1980-11-21 1986-04-16 Loctite Corp Two part adhesive composition
US5250430A (en) 1987-06-29 1993-10-05 Massachusetts Institute Of Technology Polyhydroxyalkanoate polymerase
US5245023A (en) * 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US4876331A (en) 1987-08-18 1989-10-24 Mitsubishi Kasei Corporation Copolyester and process for producing the same
US4876831A (en) * 1988-03-14 1989-10-31 Runyon John F Folding modular building structure
US5004664A (en) 1989-02-27 1991-04-02 Xerox Corporation Toner and developer compositions containing biodegradable semicrystalline polyesters
US5371002A (en) * 1989-06-07 1994-12-06 James Madison University Method of production of poly-beta-hydroxyalkanoate copolymers
ATE227340T1 (de) 1989-07-10 2002-11-15 Massachusetts Inst Technology Eine zur herstellung von polyhydroxybutyrat oder einem anderen polyhydroxyalkanoat geeignete pflanze oder pflanzliche zelle
IE893328A1 (en) 1989-10-16 1991-04-24 Mcdaid Denis Telephone lock
GB9108756D0 (en) 1991-04-24 1991-06-12 Ici Plc Production of polyalkanoate in plants
US5286842A (en) 1991-07-01 1994-02-15 Mitsubishi Kasei Corporation Process for producing a biodegradable polymer
GB9115245D0 (en) 1991-07-16 1991-08-28 Ici Plc Production of polyalkanoate
JP3696233B2 (ja) 1991-07-19 2005-09-14 ミシガン、ステート、ユニバーシティー ポリヒドロキシアルカノエートを生産するトランスジェニック植物
US5610041A (en) 1991-07-19 1997-03-11 Board Of Trustees Operating Michigan State University Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
BR9203053A (pt) 1991-08-07 1993-03-30 Ajinomoto Kk Processo para produzir acido l-glutamico pro fermentacao
JP2777757B2 (ja) 1991-09-17 1998-07-23 鐘淵化学工業株式会社 共重合体およびその製造方法
GB9223332D0 (en) * 1992-11-06 1992-12-23 Ici Plc Production of polyhydroxyalkanoate in plants
AU5676394A (en) 1992-11-20 1994-06-22 Agracetus, Inc. Transgenic cotton plants producing heterologous bioplastic
JP3263710B2 (ja) 1992-12-11 2002-03-11 高砂香料工業株式会社 生分解性光学活性ポリマー及びその製造方法
US6849427B1 (en) 1993-03-12 2005-02-01 Immulogic Pharmaceutical Corp. Nucleic acids encoding a house dust mite allergen, Der p VII, and uses therefor
IL108947A0 (en) 1993-03-12 1994-06-24 Osteopharm Ltd Bone stimulating factor
JP3241505B2 (ja) 1993-08-11 2001-12-25 高砂香料工業株式会社 生分解性光学活性コポリマー及びその製造方法
ATE314410T1 (de) 1994-01-28 2006-01-15 Procter & Gamble Biologisch abbaubare copolymere und kunststoffgegenstände aus biologisch abbaubaren 3-hydroxyhexanoat copolymeren
ID23491A (id) 1994-01-28 1995-09-07 Procter & Gamble Kopolimer-kopolimer yang dapat dibiodegradasi dan baha-bahan plastik yang terdiri dari kopolimer-kopolimer yang dapat dibiodegradasi
CA2125313A1 (en) * 1994-06-07 1995-12-08 Gerald E. O'grady Method and apparatus for producing electrical energy within the body of a ruminant
US5563239A (en) 1994-11-09 1996-10-08 Eastman Chemical Company Composition and process for the production of poly(3-hydroxyalkanoates)
BE1008983A6 (fr) 1994-12-30 1996-10-01 Faco Sa Bigoudi.
US5763270A (en) 1995-06-07 1998-06-09 Genemedicine, Inc. Plasmid for delivery of nucleic acids to cells and methods of use
GB9602796D0 (en) 1996-02-12 1996-04-10 Innes John Centre Innov Ltd Genetic control of plant growth and development
EP0977865A1 (en) * 1997-02-13 2000-02-09 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004065609A1 (ja) 2003-01-22 2004-08-05 Showa Denko K.K. アシルコエンザイムａを用いるアシル基転移酵素反応方法
JP2006000091A (ja) * 2004-05-20 2006-01-05 Mitsubishi Chemicals Corp オキザロ酢酸またはオキザロ酢酸誘導体の製造方法
JP2012511912A (ja) * 2008-12-12 2012-05-31 メタボリックス，インコーポレイテッド ポリ（５ｈｖ）および５炭素化合物を製造するための環境に優しい方法および組成物
JP2015211681A (ja) * 2008-12-12 2015-11-26 メタボリックス，インコーポレイテッド ポリ（５ｈｖ）および５炭素化合物を製造するための環境に優しい方法および組成物
WO2013035372A1 (ja) * 2011-09-05 2013-03-14 独立行政法人理化学研究所 長主鎖構造を有するポリヒドロキシアルカン酸の製造方法
US9447441B2 (en) 2011-09-05 2016-09-20 Riken Method for producing polyhydroxyalkanoate having long main chain structure
JP2019503188A (ja) * 2016-01-28 2019-02-07 コリア アドバンスト インスティチュート オブ サイエンス アンド テクノロジー キシロースからポリ（ラクテート‐ｃｏ‐グリコレート）またはその共重合体生産能を有する組換え微生物、およびそれを用いたポリ（ラクテート‐ｃｏ‐グリコレート）またはその共重合体の製造方法
US10640774B2 (en) 2016-01-28 2020-05-05 Korea Advanced Institute Of Science And Technology Recombinant microorganism having ability to produce poly(lactate-coglycolate) or copolymer thereof from xylose and method for preparing poly(lactate-coglycolate) or copolymer thereof by using same
JPWO2020179613A1 (enExample) * 2019-03-06 2020-09-10
JP7503537B2 (ja) 2019-03-06 2024-06-20 三菱商事ライフサイエンス株式会社 キノコ菌糸体を用いた食品素材

Also Published As

Publication number Publication date
US20040137586A1 (en) 2004-07-15
JP2003310262A (ja) 2003-11-05
ATE323152T1 (de) 2006-04-15
CA2303070C (en) 2011-03-15
US20020187530A1 (en) 2002-12-12
JP2009171960A (ja) 2009-08-06
DE69834199T2 (de) 2006-12-14
US20060084155A1 (en) 2006-04-20
US7229804B2 (en) 2007-06-12
DE69838768T2 (de) 2008-10-30
US20100093043A1 (en) 2010-04-15
US6689589B2 (en) 2004-02-10
EP1015565A2 (en) 2000-07-05
DE69834199D1 (de) 2006-05-24
JP2009082147A (ja) 2009-04-23
US6316262B1 (en) 2001-11-13
AU9496898A (en) 1999-04-05
DE69838768D1 (de) 2008-01-03
WO1999014313A2 (en) 1999-03-25
EP1015565B1 (en) 2006-04-12
WO1999014313A3 (en) 1999-06-03
CA2303070A1 (en) 1999-03-25
AU725516B2 (en) 2000-10-12
US7081357B2 (en) 2006-07-25
US20110008856A1 (en) 2011-01-13

Similar Documents

Publication Publication Date Title
US7081357B2 (en) Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids
JP4623829B2 (ja) トランスジェニック微生物のポリヒドロキシアルカノエート産生
JP6223386B2 (ja) ポリ（５ｈｖ）および５炭素化合物を製造するための環境に優しい方法および組成物
Snell et al. Polyhydroxyalkanoate polymers and their production in transgenic plants
EP1208208B1 (en) Transgenic systems for the manufacture of poly(3-hydroxy -butyrate -co -3- hydroxyhexanoate)
Valentin et al. Poly (3‐hydroxybutyrate‐co‐4‐hydroxybutyrate) formation from γ‐aminobutyrate and glutamate
EP1710302B1 (en) Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids
EP1700909B1 (en) Transgenic microbial polyhydroxyalkanoate producers
BRPI0922410B1 (pt) Microrganismo recombinante geneticamente modificado para converter 5aminopentanoato em um polímero ou copolímero de polihidroxialcanoato (pha) do mesmo compreendendo 5-hidróxi-valerato, e método para a produção de polímeros ou copolímeros de polihidroxialcanoato (pha) com base em carbonos dos mesmos

Legal Events

Date Code Title Description
A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20030110

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20070411

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20070416

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20081211

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20081128

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20081226