JP2001166214A - 光学装置 - Google Patents
光学装置Info
- Publication number
- JP2001166214A JP2001166214A JP34478699A JP34478699A JP2001166214A JP 2001166214 A JP2001166214 A JP 2001166214A JP 34478699 A JP34478699 A JP 34478699A JP 34478699 A JP34478699 A JP 34478699A JP 2001166214 A JP2001166214 A JP 2001166214A
- Authority
- JP
- Japan
- Prior art keywords
- illumination
- optical system
- observation
- lens
- optical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003287 optical effect Effects 0.000 title claims abstract description 1100
- 238000005286 illumination Methods 0.000 claims abstract description 658
- 238000003384 imaging method Methods 0.000 claims abstract description 69
- 230000007246 mechanism Effects 0.000 claims description 31
- 230000005284 excitation Effects 0.000 abstract description 144
- 238000010521 absorption reaction Methods 0.000 description 72
- 238000010586 diagram Methods 0.000 description 68
- 210000001747 pupil Anatomy 0.000 description 62
- 230000008859 change Effects 0.000 description 21
- 239000011521 glass Substances 0.000 description 17
- 230000004907 flux Effects 0.000 description 15
- 239000000463 material Substances 0.000 description 15
- 230000002093 peripheral effect Effects 0.000 description 13
- 238000002834 transmittance Methods 0.000 description 10
- 241000276498 Pollachius virens Species 0.000 description 9
- 230000006870 function Effects 0.000 description 8
- 238000003780 insertion Methods 0.000 description 8
- 230000037431 insertion Effects 0.000 description 8
- 230000003595 spectral effect Effects 0.000 description 7
- 230000005540 biological transmission Effects 0.000 description 6
- 239000007850 fluorescent dye Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 230000004044 response Effects 0.000 description 4
- 229910052710 silicon Inorganic materials 0.000 description 4
- 239000010703 silicon Substances 0.000 description 4
- 230000004075 alteration Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 238000002073 fluorescence micrograph Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 102000034287 fluorescent proteins Human genes 0.000 description 2
- 108091006047 fluorescent proteins Proteins 0.000 description 2
- 230000001678 irradiating effect Effects 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 101710112287 DNA-directed RNA polymerases I and III subunit RPAC2 Proteins 0.000 description 1
- 241000255581 Drosophila <fruit fly, genus> Species 0.000 description 1
- 101710183183 Probable DNA-directed RNA polymerases I and III subunit RPAC2 Proteins 0.000 description 1
- 102100034616 Protein POLR1D, isoform 2 Human genes 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000005499 meniscus Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229940070376 protein Drugs 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/18—Arrangements with more than one light path, e.g. for comparing two specimens
- G02B21/20—Binocular arrangements
- G02B21/22—Stereoscopic arrangements
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Microscoopes, Condenser (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34478699A JP2001166214A (ja) | 1999-12-03 | 1999-12-03 | 光学装置 |
| DE10059184A DE10059184A1 (de) | 1999-12-03 | 2000-11-29 | Optische Vorrichtung |
| US09/726,479 US6809861B2 (en) | 1999-12-03 | 2000-12-01 | Optical apparatus |
| US10/673,580 US20040085628A1 (en) | 1999-12-03 | 2003-09-30 | Optical apparatus |
| US11/147,460 US7649684B2 (en) | 1999-12-03 | 2005-06-08 | Optical apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34478699A JP2001166214A (ja) | 1999-12-03 | 1999-12-03 | 光学装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001166214A true JP2001166214A (ja) | 2001-06-22 |
| JP2001166214A5 JP2001166214A5 (https=) | 2007-01-18 |
Family
ID=18371983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP34478699A Pending JP2001166214A (ja) | 1999-12-03 | 1999-12-03 | 光学装置 |
Country Status (3)
| Country | Link |
|---|---|
| US (3) | US6809861B2 (https=) |
| JP (1) | JP2001166214A (https=) |
| DE (1) | DE10059184A1 (https=) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005096059A1 (ja) * | 2004-03-31 | 2005-10-13 | Olympus Corporation | 観察装置および蛍光観察装置 |
| JP2005316362A (ja) * | 2004-03-31 | 2005-11-10 | Olympus Corp | 観察装置および蛍光観察装置 |
| JP2007079562A (ja) * | 2005-08-26 | 2007-03-29 | Leica Microsystems (Schweiz) Ag | グリノー式実体顕微鏡 |
| WO2007034889A1 (ja) * | 2005-09-22 | 2007-03-29 | Olympus Corporation | 顕微鏡 |
| JP2007086503A (ja) * | 2005-09-22 | 2007-04-05 | Olympus Corp | 顕微鏡 |
| JP2007114465A (ja) * | 2005-10-20 | 2007-05-10 | Olympus Corp | 顕微鏡 |
| JP2007256414A (ja) * | 2006-03-22 | 2007-10-04 | Olympus Corp | 顕微鏡装置 |
| CN100416333C (zh) * | 2004-03-31 | 2008-09-03 | 奥林巴斯株式会社 | 观察装置 |
| JP2010139675A (ja) * | 2008-12-11 | 2010-06-24 | V Technology Co Ltd | 蛍光顕微鏡 |
| CN102004306A (zh) * | 2010-10-22 | 2011-04-06 | 桂林市迈特光学仪器有限公司 | 内置落射照明视频显微镜 |
| CN104849850A (zh) * | 2015-05-25 | 2015-08-19 | 梧州市产品质量检验所 | 一种观测宝石的装置 |
| JP2016017876A (ja) * | 2014-07-09 | 2016-02-01 | 日本板硝子株式会社 | 蛍光検出用光学装置 |
| JP2020106535A (ja) * | 2020-02-18 | 2020-07-09 | 日本板硝子株式会社 | 蛍光検出用光学装置 |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001166214A (ja) * | 1999-12-03 | 2001-06-22 | Olympus Optical Co Ltd | 光学装置 |
| JP2001318309A (ja) * | 2000-05-12 | 2001-11-16 | Canon Inc | 撮影レンズ及びそれを用いた光学機器 |
| US6888148B2 (en) * | 2001-12-10 | 2005-05-03 | Carl Zeiss Jena Gmbh | Arrangement for the optical capture of excited and /or back scattered light beam in a sample |
| JP3534733B2 (ja) | 2001-12-28 | 2004-06-07 | 三鷹光器株式会社 | 固定高倍率切換型顕微鏡 |
| DE10355523A1 (de) * | 2003-11-21 | 2005-08-11 | Carl Zeiss Jena Gmbh | Auflicht-Fluoreszenz-Stereomikroskop |
| DE10356154B4 (de) * | 2003-12-02 | 2006-04-20 | Leica Microsystems (Schweiz) Ag | Wechselvorrichtung für optische Elemente |
| DE102005046476A1 (de) * | 2004-10-01 | 2006-04-13 | Carl Zeiss Jena Gmbh | Mikroskopobjektiv |
| WO2006037473A1 (de) * | 2004-10-01 | 2006-04-13 | Carl Zeiss Jena Gmbh | Mikroskopobjektiv |
| US20060092503A1 (en) * | 2004-10-26 | 2006-05-04 | University Of Maryland, Baltimore | Portable microscope with detachable portion |
| US7593157B2 (en) * | 2004-11-29 | 2009-09-22 | Nikon Corporation | Zoom microscope |
| US7477931B2 (en) * | 2004-12-06 | 2009-01-13 | Cambridge Research & Instruments, Inc. | Systems and methods for in-vivo and optical imaging and measurement |
| DE102006036300B4 (de) * | 2005-08-26 | 2007-11-29 | Leica Microsystems (Schweiz) Ag | Hochleistungs-Stereomikroskop |
| DE102005040473B4 (de) * | 2005-08-26 | 2007-05-24 | Leica Microsystems (Schweiz) Ag | Stereomikroskop |
| JP4996183B2 (ja) * | 2005-10-26 | 2012-08-08 | オリンパス株式会社 | 顕微鏡およびランプハウス |
| DE102006004232C5 (de) | 2006-01-30 | 2013-08-01 | Carl Zeiss Surgical Gmbh | Mikroskopiesystem |
| US7324272B1 (en) * | 2006-02-02 | 2008-01-29 | Thermo Electron Scientific Instruments Llc | Spectroscopic microscope with multi-mode illumination |
| US7576911B1 (en) * | 2006-07-11 | 2009-08-18 | Roy Larimer | Variable aperture transmissive substage microscope illuminator |
| JP5021254B2 (ja) * | 2006-09-06 | 2012-09-05 | オリンパス株式会社 | 顕微鏡装置の制御方法、顕微鏡装置 |
| DE602008000515D1 (de) * | 2007-02-05 | 2010-03-04 | Olympus Corp | Laser-Scanning-Mikroskop |
| EP2175302B1 (en) * | 2007-08-07 | 2018-09-19 | Nikon Corporation | Microscope |
| JP2009288321A (ja) * | 2008-05-27 | 2009-12-10 | Olympus Corp | 顕微鏡 |
| JP2009300916A (ja) * | 2008-06-17 | 2009-12-24 | Olympus Medical Systems Corp | 光源光学系 |
| DE102009039434B4 (de) | 2009-08-31 | 2023-08-10 | Carl Zeiss Microscopy Gmbh | Stereomikroskop |
| DE102010044503B4 (de) * | 2010-09-06 | 2017-11-02 | Leica Microsystems (Schweiz) Ag | Fluoreszenz-Operations-Stereomikroskop |
| JP2013109010A (ja) * | 2011-11-17 | 2013-06-06 | Canon Inc | 立体映像撮影システム |
| CN103076677A (zh) * | 2013-02-01 | 2013-05-01 | 桂林电子科技大学 | 一种双远心柯勒照明光路 |
| JP2014170084A (ja) * | 2013-03-04 | 2014-09-18 | Mitaka Koki Co Ltd | 手術顕微鏡システム |
| DE102013009817B4 (de) | 2013-06-11 | 2019-10-31 | Carl Zeiss Meditec Ag | Mikroskopiesystem zur Beobachtung von Fluoreszenz in der Ophthalmologie |
| US8958147B2 (en) * | 2013-06-14 | 2015-02-17 | Computer Power Supply, Inc. | Apparatus for aiding manual, mechanical alignment of optical equipment |
| DE102015101847B4 (de) * | 2015-02-10 | 2017-11-02 | Eyesense Gmbh | Strahlteiler und Anordnung zur Untersuchung einer mittels elektromagnetischer Strahlung anregbaren Probe |
| JP6619996B2 (ja) * | 2015-11-24 | 2019-12-11 | 三鷹光器株式会社 | 手術用立体観察装置 |
| JP6997207B2 (ja) * | 2017-03-22 | 2022-01-17 | アルコン インコーポレイティド | 再設定可能な外科用顕微鏡 |
| WO2020150749A1 (en) * | 2019-01-18 | 2020-07-23 | Essenlix Corporation | Multi-mode illumination system |
| CN113219641B (zh) * | 2021-04-27 | 2022-03-08 | 北京航空航天大学 | 一种体视角可调的连续变焦体视显微镜 |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63133115A (ja) * | 1986-11-26 | 1988-06-04 | Nikon Corp | 光学顕微鏡 |
| JPS63194217A (ja) * | 1987-02-07 | 1988-08-11 | Canon Inc | 手術用顕微鏡 |
| JPH04144554A (ja) * | 1990-10-03 | 1992-05-19 | Topcon Corp | 手術用顕微鏡 |
| JPH04246607A (ja) * | 1990-09-08 | 1992-09-02 | Carl Zeiss:Fa | 手術用顕微鏡の照明手段 |
| JPH05127096A (ja) * | 1991-05-16 | 1993-05-25 | Olympus Optical Co Ltd | 紫外線顕微鏡 |
| JPH0757226B2 (ja) * | 1986-10-27 | 1995-06-21 | オリンパス光学工業株式会社 | 手術用顕微鏡 |
| JPH11218690A (ja) * | 1998-02-04 | 1999-08-10 | Olympus Optical Co Ltd | 落射蛍光照明光学系を備えた顕微鏡 |
| JPH11231227A (ja) * | 1998-02-10 | 1999-08-27 | Olympus Optical Co Ltd | 実体顕微鏡 |
| JPH11242189A (ja) * | 1997-12-25 | 1999-09-07 | Olympus Optical Co Ltd | 像形成法、像形成装置 |
| JPH11258514A (ja) * | 1998-01-06 | 1999-09-24 | Olympus Optical Co Ltd | 手術用顕微鏡 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4498742A (en) * | 1981-09-10 | 1985-02-12 | Nippon Kogaku K.K. | Illumination optical arrangement |
| DE3339172A1 (de) * | 1983-10-28 | 1985-05-15 | Fa. Carl Zeiss, 7920 Heidenheim | Lichtfalle fuer augenuntersuchungsgeraete |
| DE3427592A1 (de) | 1984-07-26 | 1986-02-06 | Fa. Carl Zeiss, 7920 Heidenheim | Koaxiales beleuchtungssystem fuer operationsmikroskope |
| JP2855271B2 (ja) * | 1987-06-30 | 1999-02-10 | 株式会社トプコン | 照明・観察光学装置 |
| DE4131737C2 (de) * | 1991-09-24 | 1997-05-07 | Zeiss Carl Fa | Autofokus-Anordnung für ein Stereomikroskop |
| US5434703A (en) * | 1991-10-09 | 1995-07-18 | Fuji Photo Optical Co., Ltd. | Binocular stereomicroscope |
| DE4243488A1 (de) * | 1992-12-22 | 1994-06-23 | Zeiss Carl Fa | Operationsmikroskop |
| JPH08164155A (ja) * | 1994-12-14 | 1996-06-25 | Nikon Corp | 眼科用照明装置 |
| DE29601263U1 (de) * | 1996-01-25 | 1997-05-28 | J.D. Möller Optische Werke GmbH, 22880 Wedel | Beleuchtungsvorrichtung für ein Operationsmikroskop |
| US6226118B1 (en) * | 1997-06-18 | 2001-05-01 | Olympus Optical Co., Ltd. | Optical microscope |
| DE59802165D1 (de) * | 1997-09-05 | 2001-12-20 | Leica Microsystems | Mikroskop, insbesondere fluoreszenzmikroskop, insbesondere stereo-fluoreszenzmikroskop |
| US6081371A (en) * | 1998-01-06 | 2000-06-27 | Olympus Optical Co., Ltd. | Surgical microscope including a first image and a changing projection position of a second image |
| DE19822255C2 (de) * | 1998-05-18 | 2001-07-05 | Zeiss Carl Jena Gmbh | Auflicht-Beleuchtungsanordnung für ein Stereomikroskop |
| JPH11344675A (ja) * | 1998-05-29 | 1999-12-14 | Nikon Corp | 倒立顕微鏡 |
| US6603537B1 (en) * | 1998-08-21 | 2003-08-05 | Surromed, Inc. | Optical architectures for microvolume laser-scanning cytometers |
| JP3062542U (ja) * | 1999-07-01 | 1999-10-08 | 株式会社オービック・ビジネス・コンサルタント | 複数の通信プログラムに対応したエレクトロニック・バンキング装置 |
| JP2001166214A (ja) * | 1999-12-03 | 2001-06-22 | Olympus Optical Co Ltd | 光学装置 |
| DE10119369B4 (de) * | 2000-05-31 | 2008-11-27 | Carl Zeiss | Beobachtungsvorrichtung |
-
1999
- 1999-12-03 JP JP34478699A patent/JP2001166214A/ja active Pending
-
2000
- 2000-11-29 DE DE10059184A patent/DE10059184A1/de not_active Ceased
- 2000-12-01 US US09/726,479 patent/US6809861B2/en not_active Expired - Fee Related
-
2003
- 2003-09-30 US US10/673,580 patent/US20040085628A1/en not_active Abandoned
-
2005
- 2005-06-08 US US11/147,460 patent/US7649684B2/en not_active Expired - Fee Related
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0757226B2 (ja) * | 1986-10-27 | 1995-06-21 | オリンパス光学工業株式会社 | 手術用顕微鏡 |
| JPS63133115A (ja) * | 1986-11-26 | 1988-06-04 | Nikon Corp | 光学顕微鏡 |
| JPS63194217A (ja) * | 1987-02-07 | 1988-08-11 | Canon Inc | 手術用顕微鏡 |
| JPH04246607A (ja) * | 1990-09-08 | 1992-09-02 | Carl Zeiss:Fa | 手術用顕微鏡の照明手段 |
| JPH04144554A (ja) * | 1990-10-03 | 1992-05-19 | Topcon Corp | 手術用顕微鏡 |
| JPH05127096A (ja) * | 1991-05-16 | 1993-05-25 | Olympus Optical Co Ltd | 紫外線顕微鏡 |
| JPH11242189A (ja) * | 1997-12-25 | 1999-09-07 | Olympus Optical Co Ltd | 像形成法、像形成装置 |
| JPH11258514A (ja) * | 1998-01-06 | 1999-09-24 | Olympus Optical Co Ltd | 手術用顕微鏡 |
| JPH11218690A (ja) * | 1998-02-04 | 1999-08-10 | Olympus Optical Co Ltd | 落射蛍光照明光学系を備えた顕微鏡 |
| JPH11231227A (ja) * | 1998-02-10 | 1999-08-27 | Olympus Optical Co Ltd | 実体顕微鏡 |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005316362A (ja) * | 2004-03-31 | 2005-11-10 | Olympus Corp | 観察装置および蛍光観察装置 |
| WO2005096059A1 (ja) * | 2004-03-31 | 2005-10-13 | Olympus Corporation | 観察装置および蛍光観察装置 |
| CN100416333C (zh) * | 2004-03-31 | 2008-09-03 | 奥林巴斯株式会社 | 观察装置 |
| US7589839B2 (en) | 2004-03-31 | 2009-09-15 | Olympus Corporation | Examination apparatus, fluoroscopy apparatus, examination method, and experimental method |
| JP2007079562A (ja) * | 2005-08-26 | 2007-03-29 | Leica Microsystems (Schweiz) Ag | グリノー式実体顕微鏡 |
| US7911689B2 (en) | 2005-09-22 | 2011-03-22 | Olympus Corporation | Microscope |
| WO2007034889A1 (ja) * | 2005-09-22 | 2007-03-29 | Olympus Corporation | 顕微鏡 |
| JP2007086503A (ja) * | 2005-09-22 | 2007-04-05 | Olympus Corp | 顕微鏡 |
| JP2007114465A (ja) * | 2005-10-20 | 2007-05-10 | Olympus Corp | 顕微鏡 |
| JP2007256414A (ja) * | 2006-03-22 | 2007-10-04 | Olympus Corp | 顕微鏡装置 |
| JP2010139675A (ja) * | 2008-12-11 | 2010-06-24 | V Technology Co Ltd | 蛍光顕微鏡 |
| CN102004306A (zh) * | 2010-10-22 | 2011-04-06 | 桂林市迈特光学仪器有限公司 | 内置落射照明视频显微镜 |
| JP2016017876A (ja) * | 2014-07-09 | 2016-02-01 | 日本板硝子株式会社 | 蛍光検出用光学装置 |
| CN104849850A (zh) * | 2015-05-25 | 2015-08-19 | 梧州市产品质量检验所 | 一种观测宝石的装置 |
| JP2020106535A (ja) * | 2020-02-18 | 2020-07-09 | 日本板硝子株式会社 | 蛍光検出用光学装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| US6809861B2 (en) | 2004-10-26 |
| US20010003490A1 (en) | 2001-06-14 |
| US20050231799A1 (en) | 2005-10-20 |
| US7649684B2 (en) | 2010-01-19 |
| DE10059184A1 (de) | 2001-08-23 |
| US20040085628A1 (en) | 2004-05-06 |
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