|
EP0809492A4
(en)
*
|
1995-02-17 |
2007-01-24 |
Smithkline Beecham Corp |
IL-8 RECEPTOR ANTAGONISTS
|
|
US5807876A
(en)
|
1996-04-23 |
1998-09-15 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of IMPDH enzyme
|
|
US6054472A
(en)
*
|
1996-04-23 |
2000-04-25 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of IMPDH enzyme
|
|
US6211373B1
(en)
*
|
1996-03-20 |
2001-04-03 |
Smithkline Beecham Corporation |
Phenyl urea antagonists of the IL-8 receptor
|
|
DE69709647T2
(de)
|
1996-05-20 |
2002-11-07 |
Dupont Pharmaceuticals Research Laboratories, Inc. |
Cyclischer diarylalkyl diaminederivate als antogoniste von chemokinerezeptoren
|
|
WO1997049399A1
(en)
*
|
1996-06-27 |
1997-12-31 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
US6177448B1
(en)
|
1996-08-06 |
2001-01-23 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
JP2001523220A
(ja)
*
|
1996-08-06 |
2001-11-20 |
スミスクライン・ビーチャム・コーポレイション |
Ｉｌ―８受容体アンタゴニスト
|
|
WO1998006398A1
(en)
*
|
1996-08-15 |
1998-02-19 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
WO1998017312A1
(en)
*
|
1996-10-22 |
1998-04-30 |
Chugai Seiyaku Kabushiki Kaisha |
Sepsis remedy comprising anti-il-8 antibody as active ingredient
|
|
DE19651040C2
(de)
*
|
1996-12-09 |
1999-01-28 |
Bayer Ag |
Verfahren zur Herstellung von 2-Amino-5-alkyl-phenolen
|
|
US6300325B1
(en)
|
1997-01-23 |
2001-10-09 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
US6436927B1
(en)
|
1997-02-12 |
2002-08-20 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
AU6435098A
(en)
*
|
1997-02-12 |
1998-08-26 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
US6696475B2
(en)
|
1997-04-22 |
2004-02-24 |
Neurosearch A/S |
Substituted phenyl derivatives, their preparation and use
|
|
WO2000024707A1
(en)
*
|
1998-10-22 |
2000-05-04 |
Neurosearch A/S |
Substituted phenyl derivatives, their preparation and use
|
|
US6344476B1
(en)
*
|
1997-05-23 |
2002-02-05 |
Bayer Corporation |
Inhibition of p38 kinase activity by aryl ureas
|
|
EP1014962A4
(en)
*
|
1997-06-26 |
2007-06-27 |
Lilly Co Eli |
ANTITHROMBOTIC AGENTS
|
|
AU8673198A
(en)
*
|
1997-07-29 |
1999-02-22 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
US7067117B1
(en)
|
1997-09-11 |
2006-06-27 |
Cambridge University Technical Services, Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
US6989435B2
(en)
|
1997-09-11 |
2006-01-24 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
ES2153340T3
(es)
*
|
1997-12-22 |
2006-02-01 |
Bayer Pharmaceuticals Corp. |
Inhibicion de la quinasa raf utilizando ureas heterociclicas sustituidas.
|
|
US20080300281A1
(en)
*
|
1997-12-22 |
2008-12-04 |
Jacques Dumas |
Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
|
|
DE69829412T2
(de)
*
|
1997-12-22 |
2005-07-28 |
Bayer Pharmaceuticals Corp., West Haven |
Hemmung der raf-kinase unter verwendung von symmetrisch und unsymmetrisch substituierten harnstoffen
|
|
US7329670B1
(en)
|
1997-12-22 |
2008-02-12 |
Bayer Pharmaceuticals Corporation |
Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
|
|
US7517880B2
(en)
|
1997-12-22 |
2009-04-14 |
Bayer Pharmaceuticals Corporation |
Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
|
|
AU2003204708B2
(en)
*
|
1997-12-22 |
2006-05-25 |
Bayer Healthcare Llc |
Inhibition of Raf Kinase using Substituted Heterocyclic Ureas
|
|
EP1087661A4
(en)
*
|
1998-06-17 |
2003-04-16 |
Smithkline Beecham Corp |
IL-8 RECEPTOR ANTAGONISTS
|
|
HUP0102863A3
(en)
*
|
1998-07-23 |
2002-05-28 |
Smithkline Beecham Corp |
Il-8 receptor antagonists benzimidazole derivatives, process for their preparation and medicaments containing them
|
|
JP2002523487A
(ja)
*
|
1998-08-28 |
2002-07-30 |
スミスクライン・ビーチャム・コーポレイション |
３−ヒドロキシ−４−アミノ−ベンゾニトリルの改良された合成方法
|
|
US6262090B1
(en)
|
1998-12-09 |
2001-07-17 |
American Home Products Corporation |
Aminopyridine-containing thiourea inhibitors of herpes viruses
|
|
IL143183A0
(en)
*
|
1998-12-09 |
2002-04-21 |
American Home Prod |
Alpha-methylbenzyl-containing thiourea inhibitors of herpres viruses containing a phenylenediamine group
|
|
US6207715B1
(en)
|
1998-12-09 |
2001-03-27 |
American Home Products Corporation |
Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a substituted phenylene-diamine group
|
|
US6197803B1
(en)
|
1998-12-09 |
2001-03-06 |
American Home Products Corporation |
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group
|
|
CZ20011957A3
(cs)
*
|
1998-12-09 |
2001-10-17 |
American Home Products Corporation |
Thiomočoviny jako inhibitory herpes virů
|
|
US6201013B1
(en)
|
1998-12-09 |
2001-03-13 |
American Home Products Corporation |
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing a substituted phenylenediamine group
|
|
US6166028A
(en)
|
1998-12-09 |
2000-12-26 |
American Home Products Corporation |
Diaminopuridine-containing thiourea inhibitors of herpes viruses
|
|
US6335350B1
(en)
|
1998-12-09 |
2002-01-01 |
American Home Products Corporation |
Acetamide and substituted acetamide-containing thiourea inhibitors of herpes viruses
|
|
US6255349B1
(en)
|
1998-12-09 |
2001-07-03 |
American Home Products Corporation |
Alph-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
|
|
US20080269265A1
(en)
*
|
1998-12-22 |
2008-10-30 |
Scott Miller |
Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
|
|
CA2359244C
(en)
|
1999-01-13 |
2013-10-08 |
Bayer Corporation |
.omega.-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
|
|
WO2000042012A1
(en)
*
|
1999-01-13 |
2000-07-20 |
Bayer Corporation |
φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
|
|
US7928239B2
(en)
|
1999-01-13 |
2011-04-19 |
Bayer Healthcare Llc |
Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
|
|
RU2319693C9
(ru)
*
|
1999-01-13 |
2008-08-20 |
Байер Копэрейшн |
Производные мочевины (варианты), фармацевтическая композиция (варианты) и способ лечения заболевания, связанного с ростом раковых клеток (варианты)
|
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
UA73492C2
(en)
|
1999-01-19 |
2005-08-15 |
|
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
MXPA01008440A
(es)
|
1999-02-22 |
2002-04-24 |
Boehringer Ingelheim Pharma |
Derivados heterociclicos policiclos como agentes anti-inflamatorios..
|
|
CA2361998C
(en)
*
|
1999-03-12 |
2009-04-07 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as anti-inflammatory agents
|
|
CN1511830A
(zh)
|
1999-03-12 |
2004-07-14 |
���ָ��.Ӣ��ķҩ�﹫˾ |
作为消炎剂的化合物
|
|
DK1163212T3
(da)
*
|
1999-03-17 |
2005-11-14 |
Astrazeneca Ab |
Amidderivater
|
|
CO5170528A1
(es)
*
|
1999-05-28 |
2002-06-27 |
Smithkline Beecham Corp |
Antagonistas de los receptores de la il-8 nistas del recpetor de la il-8
|
|
CO5190710A1
(es)
*
|
1999-06-15 |
2002-08-29 |
Smithkline Beecham Corp |
Antagonistas de un receptor de il-8 un receptor de il-8
|
|
CO5200760A1
(es)
*
|
1999-06-16 |
2002-09-27 |
Smithkline Beecham Corp |
Antagonistas del receptor de la il-8 ceptor il-8
|
|
EP1218353B1
(en)
*
|
1999-07-07 |
2007-10-17 |
AstraZeneca UK Limited |
Quinazoline derivatives
|
|
JP4162406B2
(ja)
|
1999-07-09 |
2008-10-08 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
ヘテロアリール置換ウレア化合物の新規合成方法
|
|
EP1557168B1
(en)
|
1999-07-26 |
2011-11-16 |
Msd K.K. |
Biarylurea Derivatives
|
|
CO5271663A1
(es)
*
|
1999-11-09 |
2003-04-30 |
Smithkline Beecham Corp |
Antagonistas del receptor il-8
|
|
ATE375334T1
(de)
|
1999-11-16 |
2007-10-15 |
Boehringer Ingelheim Pharma |
Harnstoff derivate als entzündungshemmende mittel
|
|
US6525046B1
(en)
|
2000-01-18 |
2003-02-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
US6608052B2
(en)
|
2000-02-16 |
2003-08-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compounds useful as anti-inflammatory agents
|
|
US6653347B2
(en)
*
|
2000-03-01 |
2003-11-25 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
AU2001245605A1
(en)
*
|
2000-03-10 |
2001-09-24 |
Smith Kline Beecham Corporation |
Il-8 receptor antagonists
|
|
MY133845A
(en)
|
2000-03-10 |
2007-11-30 |
Smithkline Beecham Corp |
Il-8 receptor antagonists
|
|
AU2001245724A1
(en)
*
|
2000-03-14 |
2001-09-24 |
Smith Kline Beecham Corporation |
Il-8 receptor antagonists
|
|
CO5280089A1
(es)
*
|
2000-03-16 |
2003-05-30 |
Smithkline Beecham Corp |
Antagonistas del receptor il-8
|
|
UY26627A1
(es)
*
|
2000-03-24 |
2001-09-28 |
Smithkline Beecham Corp |
Antagonistas de receptores de il-8
|
|
AU4875301A
(en)
*
|
2000-04-14 |
2001-10-30 |
Kureha Chemical Ind Co Ltd |
Nitrogenous compounds and antiviral drugs containing the same
|
|
BR0110968A
(pt)
*
|
2000-05-30 |
2005-05-10 |
Smithkline Beecham Corp |
Antagonistas dos receptores de il-8
|
|
AU2001273497A1
(en)
*
|
2000-07-18 |
2002-01-30 |
Smithkline Beecham Corporation |
Use of IL-8 receptor antagonists in the treatment of virus infections
|
|
AU2001290852A1
(en)
*
|
2000-09-15 |
2002-03-26 |
Iconix Pharmaceuticals, Inc. |
Inhibitors of rho c
|
|
US7235576B1
(en)
|
2001-01-12 |
2007-06-26 |
Bayer Pharmaceuticals Corporation |
Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
WO2002057230A1
(en)
*
|
2001-01-16 |
2002-07-25 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
JP2004520412A
(ja)
*
|
2001-01-16 |
2004-07-08 |
スミスクライン・ビーチャム・コーポレイション |
Ｉｌ−８受容体アンタゴニスト
|
|
DE10109204A1
(de)
*
|
2001-02-26 |
2002-09-19 |
4Sc Ag |
Verbindungen zur Behandlung von Protozoen-Erkrankungen
|
|
US6949567B2
(en)
|
2001-02-26 |
2005-09-27 |
4Sc Ag |
Compounds for the treatment of protozoal diseases
|
|
ITMI20010395A1
(it)
|
2001-02-27 |
2002-08-27 |
Dompe Spa |
Omega-amminoalchilammidi di acidi r-2-aril-propionici come inibitori della chemiotassi di cellule polimorfonucleate e mononucleate
|
|
EP1379508B9
(en)
|
2001-02-28 |
2011-02-09 |
Temple University - Of The Commonwealth System of Higher Education |
N-(aryl)-2-arylethenesulfonamides and therapeutic uses thereof
|
|
US7371763B2
(en)
|
2001-04-20 |
2008-05-13 |
Bayer Pharmaceuticals Corporation |
Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
|
|
CN1630517A
(zh)
*
|
2001-05-24 |
2005-06-22 |
吴羽化学工业株式会社 |
包含含氮化合物的具有cxcr4拮抗作用的药物
|
|
US20040038854A1
(en)
*
|
2001-07-16 |
2004-02-26 |
Dillon Susan B. |
Use of il-8 receptor antagonists in the treatment of virus infections
|
|
US6791892B2
(en)
*
|
2001-07-18 |
2004-09-14 |
Samsung Electronics Co., Ltd. |
Method of generating an initializing signal during power-up of semiconductor memory device
|
|
PT1450799E
(pt)
*
|
2001-12-03 |
2007-01-31 |
Bayer Pharmaceuticals Corp |
Compostos de arilureia em combinação com outros agentes citostáticos ou citotóxicos para tratamento de cancros humanos
|
|
US20080108672A1
(en)
*
|
2002-01-11 |
2008-05-08 |
Bernd Riedl |
Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
|
|
WO2003068228A1
(en)
|
2002-02-11 |
2003-08-21 |
Bayer Pharmaceuticals Corporation |
Aryl ureas with angiogenesis inhibiting activity
|
|
US20040023961A1
(en)
*
|
2002-02-11 |
2004-02-05 |
Bayer Corporation |
Aryl ureas with raf kinase and angiogenisis inhibiting activity
|
|
WO2003068229A1
(en)
|
2002-02-11 |
2003-08-21 |
Bayer Pharmaceuticals Corporation |
Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
|
|
PT1580188E
(pt)
*
|
2002-02-11 |
2012-01-25 |
Bayer Healthcare Llc |
Aril-ureias como inibidores de cinases
|
|
CA2473634C
(en)
|
2002-02-25 |
2011-11-29 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
1,4-disubstituted benzofused cycloalkyl urea compounds useful in treating cytokine mediated diseases
|
|
JP4538233B2
(ja)
*
|
2002-02-28 |
2010-09-08 |
テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション |
増殖性障害治療用の、アミノ置換されたスルホンアニリド及びその誘導体
|
|
KR20030080509A
(ko)
*
|
2002-04-09 |
2003-10-17 |
주식회사 엘지생명과학 |
우레아, 티오우레아 및 설파마이드 유도체를 함유하는항균제 조성물
|
|
US20030236287A1
(en)
*
|
2002-05-03 |
2003-12-25 |
Piotrowski David W. |
Positive allosteric modulators of the nicotinic acetylcholine receptor
|
|
AU2003260280A1
(en)
*
|
2002-08-01 |
2004-02-23 |
Neurosearch A/S |
Compounds useful for the treatment of diseases responsive to antiangiogenetic therapy
|
|
CN100528846C
(zh)
*
|
2002-09-11 |
2009-08-19 |
株式会社吴羽 |
胺化合物及其用途
|
|
EP1402887A1
(en)
*
|
2002-09-18 |
2004-03-31 |
Jerini AG |
New compounds for the inhibition of undesired cell proliferation and use thereof
|
|
TW200418812A
(en)
|
2002-10-29 |
2004-10-01 |
Smithkline Beecham Corp |
IL-8 receptor antagonists
|
|
DE10251830A1
(de)
*
|
2002-11-07 |
2004-05-19 |
Wella Ag |
2-Amino-5-ethylphenol enthaltendes Mittel zum Färben von Keratinfasern
|
|
ATE431335T1
(de)
*
|
2002-11-21 |
2009-05-15 |
Neurosearch As |
Diarylureidoderivate und deren medizinische verwendung
|
|
US20040198777A1
(en)
*
|
2002-12-20 |
2004-10-07 |
Mitokor, Inc. |
Ligands of adenine nucleotide translocase (ANT) and compositions and methods related thereto
|
|
WO2004058722A1
(en)
*
|
2002-12-24 |
2004-07-15 |
Arena Pharmaceuticals, Inc. |
Diarylamine and arylheteroarylamine pyrazole derivatives as modulators of 5ht2a
|
|
US7220768B2
(en)
*
|
2003-02-11 |
2007-05-22 |
Wyeth Holdings Corp. |
Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus
|
|
NZ589793A
(en)
*
|
2003-02-21 |
2011-12-22 |
Resmed Ltd |
Nozzle configuration of nasal cushion for respiratory assistance mask
|
|
US7557129B2
(en)
*
|
2003-02-28 |
2009-07-07 |
Bayer Healthcare Llc |
Cyanopyridine derivatives useful in the treatment of cancer and other disorders
|
|
EP1457485A1
(en)
*
|
2003-03-14 |
2004-09-15 |
Dompé S.P.A. |
Sulfonic acids, their derivatives and pharmaceutical compositions containing them
|
|
JP4943837B2
(ja)
*
|
2003-04-03 |
2012-05-30 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
可溶性エポキシド加水分解酵素の改良インヒビター
|
|
WO2005089380A2
(en)
|
2004-03-16 |
2005-09-29 |
The Regents Of The University Of California |
Reducing nephropathy with inhibitors of soluble epoxide hydrolase and epoxyeicosanoids
|
|
ATE366108T1
(de)
|
2003-05-20 |
2007-07-15 |
Bayer Pharmaceuticals Corp |
Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten
|
|
TW200523253A
(en)
*
|
2003-07-22 |
2005-07-16 |
Arena Pharm Inc |
Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
|
|
DK1663978T3
(da)
|
2003-07-23 |
2008-04-07 |
Bayer Pharmaceuticals Corp |
Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser
|
|
WO2005023238A1
(en)
*
|
2003-09-04 |
2005-03-17 |
Poseidon Pharmaceuticals A/S |
Erg channel openers for the treatment of hyperexcitability-related neuronal diseases
|
|
EP1663192B1
(en)
|
2003-09-04 |
2008-12-03 |
NeuroSearch A/S |
hERG1 CHANNEL OPENERS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS
|
|
TW200530236A
(en)
|
2004-02-23 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Heteroaryl phenylurea
|
|
CN1950343B
(zh)
*
|
2004-03-10 |
2013-06-19 |
株式会社吴羽 |
胺系碱性化合物及其用途
|
|
CA2559038C
(en)
*
|
2004-03-23 |
2013-09-10 |
Arena Pharmaceuticals, Inc. |
Processes for preparing substituted n-aryl-n'-[3-(1h-pyrazol-5-yl) phenyl] ureas and intermediates thereof
|
|
CA2561639A1
(en)
*
|
2004-03-29 |
2005-10-06 |
Neurosearch A/S |
Novel urea derivatives and their medical use
|
|
JP2007535565A
(ja)
|
2004-04-30 |
2007-12-06 |
バイエル ファーマシューティカルス コーポレーション |
癌の治療に有用な置換ピラゾリル尿素誘導体
|
|
ES2340179T3
(es)
*
|
2004-05-12 |
2010-05-31 |
Bristol-Myers Squibb Company |
Antagonistas de urea del receptor p2y1 utiles en el tratamiento de afecciones tromboticas.
|
|
US7550499B2
(en)
|
2004-05-12 |
2009-06-23 |
Bristol-Myers Squibb Company |
Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
AU2005245399A1
(en)
|
2004-05-12 |
2005-12-01 |
Schering Corporation |
CXCR1 and CXCR2 chemokine antagonists
|
|
FR2872159B1
(fr)
*
|
2004-06-28 |
2007-10-05 |
Merck Sante Soc Par Actions Si |
Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete
|
|
EA012119B1
(ru)
|
2004-08-12 |
2009-08-28 |
Пфайзер Инк. |
ПРОИЗВОДНЫЕ ТРИАЗОЛОПИРИДИНСУЛЬФАНИЛА В КАЧЕСТВЕ ИНГИБИТОРОВ p38 MAP КИНАЗЫ
|
|
JP4551450B2
(ja)
*
|
2004-08-16 |
2010-09-29 |
ザ プロクター アンド ギャンブル カンパニー |
ケラチン繊維用染色剤、前記ケラチン繊維用染色剤を含有する染色組成物、及びそれらの使用
|
|
EP1634573A1
(en)
*
|
2004-08-16 |
2006-03-15 |
The Procter and Gamble Company |
2-(Amino or substituted Amino)-5,6-substituted Phenol compounds, dyeing compositions containing them, and use thereof
|
|
ZA200703613B
(en)
*
|
2004-10-20 |
2009-05-27 |
Univ California |
Improved inhibitors for the soluble epoxide hydrolase
|
|
US20070249625A1
(en)
*
|
2004-10-20 |
2007-10-25 |
Jakob Busch-Petersen |
Il-8 Receptor Antagonists
|
|
US7582673B2
(en)
|
2004-10-21 |
2009-09-01 |
High Point Pharmaceuticals, Llc |
Bissulfonamide compounds as agonists of GalR1, compositions, and methods of use
|
|
PE20061130A1
(es)
|
2004-11-19 |
2007-01-05 |
Arena Pharm Inc |
Derivados de 3-fenil-pirazol como moduladores del receptor de serotonina 5-ht2a
|
|
WO2006060762A2
(en)
*
|
2004-12-03 |
2006-06-08 |
Arena Pharmaceuticals, Inc. |
Pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
KR20070100894A
(ko)
|
2005-01-19 |
2007-10-12 |
브리스톨-마이어스 스큅 컴퍼니 |
혈전색전성 장애 치료용 ｐ2ｙ1 수용체 억제제로서의2-페녹시-ｎ-(1,3,4-티아디졸-2-일)피리딘-3-아민 유도체및 관련 화합물
|
|
CN101160127A
(zh)
*
|
2005-01-19 |
2008-04-09 |
艾尼纳制药公司 |
用于预防或治疗进行性多灶性白质脑病而作为5-ht2a血清素受体调节剂的二芳基和芳基杂芳基脲衍生物
|
|
US20090305321A1
(en)
*
|
2005-03-23 |
2009-12-10 |
Astrazeneca Ab |
Assays for Allosteric Modulators of G-Protein Coupled Receptors (GPCRs)
|
|
TW200726764A
(en)
|
2005-06-27 |
2007-07-16 |
Bristol Myers Squibb Co |
N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
DE602006017694D1
(de)
|
2005-06-27 |
2010-12-02 |
Bristol Myers Squibb Co |
C-verknüpfte zyklische antagonisten des p2y1-rezeptors mit eignung bei der behandlung thrombotischer leiden
|
|
ATE502924T1
(de)
|
2005-06-27 |
2011-04-15 |
Bristol Myers Squibb Co |
Lineare harnstoffmimetika-antagonisten des p2y1- rezeptors zur behandlung von thromboseleiden
|
|
US7714002B2
(en)
|
2005-06-27 |
2010-05-11 |
Bristol-Myers Squibb Company |
Carbocycle and heterocycle antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
GB0526255D0
(en)
|
2005-12-22 |
2006-02-01 |
Novartis Ag |
Organic compounds
|
|
EP1983971A4
(en)
*
|
2006-01-25 |
2010-11-24 |
Synta Pharmaceuticals Corp |
SUBSTITUTED AROMATIC COMPOUNDS FOR USE AGAINST INFLAMMATION AND IMMUNE DISORDERS
|
|
DK2009992T3
(da)
*
|
2006-04-21 |
2012-08-13 |
Glaxosmithkline Llc |
Il-8 receptor-antagonister
|
|
MX2008013599A
(es)
*
|
2006-04-21 |
2008-10-31 |
Smithkline Beechman Corp |
Antagonistas del receptor il-8.
|
|
WO2007127930A2
(en)
*
|
2006-04-28 |
2007-11-08 |
Kansas State University Research Foundation |
Compounds affecting gap junction activity
|
|
MX2008014622A
(es)
|
2006-05-18 |
2008-11-28 |
Arena Pharm Inc |
Formas cristalinas y procesos para la preparacion de fenil-pirazoles utiles como moduladores del receptor de serotonina 5-ht2a.
|
|
WO2007136703A1
(en)
|
2006-05-18 |
2007-11-29 |
Arena Pharmaceuticals, Inc. |
Primary amines and derivatives thereof as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
CN101479261A
(zh)
*
|
2006-05-18 |
2009-07-08 |
艾尼纳制药公司 |
3-吡唑基-苯甲酰胺-4-醚、其仲胺及其衍生物作为5-ht2a血清素受体的调节剂用于治疗与其相关的病症
|
|
CL2007001829A1
(es)
|
2006-06-23 |
2008-01-25 |
Smithkline Beecham Corp |
P-toluensulfonato de n-[4-cloro-2-hidroxi-3-(piperazina-1-sulfonil)fenil]-n-(2-cloro-3-fluorofenil)urea;procedimiento de preparacion;composicion farmaceutica;combinacion farmaceutica;y uso en el tratamiento de una enfermedad mediada por la quiimioquina il-8, tales como asma y epoc.
|
|
TWI415845B
(zh)
|
2006-10-03 |
2013-11-21 |
Arena Pharm Inc |
用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
|
|
US7960569B2
(en)
|
2006-10-17 |
2011-06-14 |
Bristol-Myers Squibb Company |
Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
WO2008047067A1
(en)
*
|
2006-10-20 |
2008-04-24 |
University Court Of The University Of Edinburgh |
Treatment of inflammatory disease
|
|
WO2009023253A2
(en)
|
2007-08-15 |
2009-02-19 |
Arena Pharmaceuticals Inc. |
IMIDAZO[L,2-α]PYRIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
|
|
CN101932557A
(zh)
*
|
2007-09-28 |
2010-12-29 |
葛兰素史密丝克莱恩有限责任公司 |
糖原磷酸化酶抑制剂化合物及其药物组合物
|
|
US20110021538A1
(en)
*
|
2008-04-02 |
2011-01-27 |
Arena Pharmaceuticals, Inc. |
Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
|
|
WO2010062321A1
(en)
|
2008-10-28 |
2010-06-03 |
Arena Pharmaceuticals, Inc. |
Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
|
|
CN104784173B
(zh)
|
2008-10-28 |
2019-07-26 |
艾尼纳制药公司 |
用于治疗5-ht2a5-羟色胺受体相关障碍的5-ht2a5-羟色胺受体调节剂组合物
|
|
WO2010092440A1
(en)
*
|
2009-02-16 |
2010-08-19 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Cxcr2 receptor antagonists for the treatment or the prevention of insulin resistance
|
|
US20120136033A1
(en)
*
|
2009-05-18 |
2012-05-31 |
President And Fellows Of Harvard College |
Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof
|
|
JP2013514313A
(ja)
*
|
2009-12-17 |
2013-04-25 |
ガルデルマ・リサーチ・アンド・デヴェロップメント |
皮膚障害の治療又は予防における化合物の使用
|
|
WO2011075596A1
(en)
|
2009-12-18 |
2011-06-23 |
Arena Pharmaceuticals, Inc. |
Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
BRPI1004176A2
(pt)
*
|
2010-10-25 |
2015-08-11 |
Univ Rio De Janeiro |
Compostos aril e/ou hetero aril uréias funcionalizados; processo de síntese desses composto; composição farmacêutica contendo tais compostos e usos
|
|
US8648118B2
(en)
|
2010-12-17 |
2014-02-11 |
Boehringer Ingelheim International Gmbh |
Bicyclic ring system substituted amide functionalised phenols as medicaments
|
|
WO2012149540A1
(en)
|
2011-04-28 |
2012-11-01 |
The Broad Institute Inc |
Inhibitors of histone deacetylase
|
|
WO2014018979A1
(en)
|
2012-07-27 |
2014-01-30 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
KR101779268B1
(ko)
*
|
2012-11-21 |
2017-09-18 |
닛뽕소다 가부시키가이샤 |
비페놀계 화합물을 사용한 기록 재료
|
|
US9914717B2
(en)
|
2012-12-20 |
2018-03-13 |
The Broad Institute, Inc. |
Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors
|
|
WO2014126018A1
(ja)
*
|
2013-02-13 |
2014-08-21 |
王子ホールディングス株式会社 |
感熱記録体
|
|
BR112015029012B1
(pt)
|
2013-05-22 |
2022-02-22 |
Oji Holdings Corporation |
Meio de gravação termossensível
|
|
JP2018516992A
(ja)
|
2015-06-12 |
2018-06-28 |
アクソファント サイエンシーズ ゲーエムベーハーＡｘｏｖａｎｔ Ｓｃｉｅｎｃｅｓ Ｇｍｂｈ |
レム睡眠行動障害の予防および処置のために有用なジアリールおよびアリールヘテロアリール尿素誘導体
|
|
EP3117835A1
(en)
*
|
2015-07-14 |
2017-01-18 |
Dompé farmaceutici s.p.a. |
Il-8 inhibitors for use in the treatment of certain urological disorders
|
|
AU2016291673A1
(en)
|
2015-07-15 |
2018-01-25 |
Axovant Sciences Gmbh |
Diaryl and arylheteroaryl urea derivatives for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease
|
|
US10093617B1
(en)
*
|
2015-10-30 |
2018-10-09 |
Sumitomo Chemical Company, Limited |
Method for producing 2-amino-4-substituted phenol
|
|
JP7092356B2
(ja)
*
|
2016-06-22 |
2022-06-28 |
フーダン ユニヴァーシティ |
ビアリール尿素誘導体またはそれらの塩、およびそれらの調製方法および使用
|
|
CN107522641B
(zh)
*
|
2016-06-22 |
2020-05-05 |
复旦大学 |
联芳基脲类衍生物或其盐及其制备方法和用途
|
|
CA3037071A1
(en)
|
2016-10-03 |
2018-04-12 |
The Children's Medical Center Corporation |
Prevention and treatment of diabetic nephropathy
|
|
CN112135610A
(zh)
|
2018-01-12 |
2020-12-25 |
KDAc治疗股份有限公司 |
用于治疗癌症的选择性组蛋白去乙酰酶3(hdac3)抑制剂及免疫治疗剂的组合
|
|
CN110698373A
(zh)
*
|
2019-11-07 |
2020-01-17 |
温州大学 |
N-（2-（甲硫基）苯基）乙酰胺类化合物的制备方法及其净化提纯方法
|
|
CN112321452B
(zh)
*
|
2020-09-11 |
2022-11-29 |
北京红惠新医药科技有限公司 |
厚朴酚衍生物、和厚朴酚衍生物及其盐酸盐、制备方法及应用
|
|
WO2025121190A1
(ja)
*
|
2023-12-08 |
2025-06-12 |
日産化学株式会社 |
重合体、樹脂組成物、液晶配向剤、樹脂被膜及び液晶配向膜
|