|
JPH11503110A
(ja)
*
|
1995-02-17 |
1999-03-23 |
スミスクライン・ビーチャム・コーポレイション |
Ｉｌ−８受容体拮抗剤
|
|
US5807876A
(en)
|
1996-04-23 |
1998-09-15 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of IMPDH enzyme
|
|
US6054472A
(en)
*
|
1996-04-23 |
2000-04-25 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of IMPDH enzyme
|
|
US6211373B1
(en)
*
|
1996-03-20 |
2001-04-03 |
Smithkline Beecham Corporation |
Phenyl urea antagonists of the IL-8 receptor
|
|
US6686353B1
(en)
|
1996-05-20 |
2004-02-03 |
Teijin Intellectual Property Center Limited |
Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
|
|
EP0907362A4
(en)
*
|
1996-06-27 |
1999-12-01 |
Smithkline Beecham Corp |
IL-8 RECEPTOR ANTAGONISTS
|
|
EP0957907A4
(en)
*
|
1996-08-06 |
2001-08-16 |
Smithkline Beecham Corp |
IL-8 RECEPTOR ANTAGONISTS
|
|
WO1998005329A1
(en)
|
1996-08-06 |
1998-02-12 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
WO1998006398A1
(en)
*
|
1996-08-15 |
1998-02-19 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
AU3048797A
(en)
*
|
1996-10-22 |
1998-05-15 |
Chugai Seiyaku Kabushiki Kaisha |
Sepsis remedy comprising anti-il-8 antibody as active ingredient
|
|
DE19651040C2
(de)
*
|
1996-12-09 |
1999-01-28 |
Bayer Ag |
Verfahren zur Herstellung von 2-Amino-5-alkyl-phenolen
|
|
US6300325B1
(en)
|
1997-01-23 |
2001-10-09 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
US6436927B1
(en)
|
1997-02-12 |
2002-08-20 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
ES2224365T3
(es)
*
|
1997-02-12 |
2005-03-01 |
Smithkline Beecham Corporation |
Antagonistas de receptores de il-8.
|
|
US6696475B2
(en)
|
1997-04-22 |
2004-02-24 |
Neurosearch A/S |
Substituted phenyl derivatives, their preparation and use
|
|
US6344476B1
(en)
*
|
1997-05-23 |
2002-02-05 |
Bayer Corporation |
Inhibition of p38 kinase activity by aryl ureas
|
|
JP2002512633A
(ja)
*
|
1997-06-26 |
2002-04-23 |
イーライ・リリー・アンド・カンパニー |
抗血栓剤
|
|
AU8673198A
(en)
*
|
1997-07-29 |
1999-02-22 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
US6989435B2
(en)
|
1997-09-11 |
2006-01-24 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
US7067117B1
(en)
|
1997-09-11 |
2006-06-27 |
Cambridge University Technical Services, Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
US7329670B1
(en)
|
1997-12-22 |
2008-02-12 |
Bayer Pharmaceuticals Corporation |
Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
|
|
US20080300281A1
(en)
*
|
1997-12-22 |
2008-12-04 |
Jacques Dumas |
Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
|
|
CN1213022C
(zh)
*
|
1997-12-22 |
2005-08-03 |
拜尔有限公司 |
用对称和不对称的取代二苯脲抑制raf激酶
|
|
DE69831013T2
(de)
*
|
1997-12-22 |
2006-04-20 |
Bayer Pharmaceuticals Corp., West Haven |
Inhibierung der raf-kinase durch substituierte heterocyclische harnstoffverbindungen
|
|
AU2003204708B2
(en)
*
|
1997-12-22 |
2006-05-25 |
Bayer Healthcare Llc |
Inhibition of Raf Kinase using Substituted Heterocyclic Ureas
|
|
US7517880B2
(en)
|
1997-12-22 |
2009-04-14 |
Bayer Pharmaceuticals Corporation |
Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
|
|
WO1999065310A1
(en)
*
|
1998-06-17 |
1999-12-23 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
CN1314893A
(zh)
*
|
1998-07-23 |
2001-09-26 |
史密丝克莱恩比彻姆公司 |
Il－8受体拮抗剂
|
|
EP1107948A4
(en)
*
|
1998-08-28 |
2002-01-02 |
Smithkline Beecham |
IMPROVED SYNTHESIS OF 3-HYDROXY-4-AMINO-BENZONITRILE
|
|
PL198852B1
(pl)
*
|
1998-10-22 |
2008-07-31 |
Neurosearch As |
Podstawione pochodne fenylu, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie
|
|
US6201013B1
(en)
|
1998-12-09 |
2001-03-13 |
American Home Products Corporation |
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing a substituted phenylenediamine group
|
|
US6335350B1
(en)
|
1998-12-09 |
2002-01-01 |
American Home Products Corporation |
Acetamide and substituted acetamide-containing thiourea inhibitors of herpes viruses
|
|
US6207715B1
(en)
|
1998-12-09 |
2001-03-27 |
American Home Products Corporation |
Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a substituted phenylene-diamine group
|
|
US6255349B1
(en)
|
1998-12-09 |
2001-07-03 |
American Home Products Corporation |
Alph-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
|
|
PT1137645E
(pt)
*
|
1998-12-09 |
2004-09-30 |
Wyeth Corp |
Inibidores virus de herpes a base de tioureia alfa-metilbenzilada contendo um grupo fenilenodiamina
|
|
US6197803B1
(en)
|
1998-12-09 |
2001-03-06 |
American Home Products Corporation |
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group
|
|
US6262090B1
(en)
|
1998-12-09 |
2001-07-17 |
American Home Products Corporation |
Aminopyridine-containing thiourea inhibitors of herpes viruses
|
|
US6166028A
(en)
|
1998-12-09 |
2000-12-26 |
American Home Products Corporation |
Diaminopuridine-containing thiourea inhibitors of herpes viruses
|
|
IL143262A0
(en)
*
|
1998-12-09 |
2002-04-21 |
American Home Prod |
Thiourea inhibitors of herpes viruses
|
|
US20080269265A1
(en)
*
|
1998-12-22 |
2008-10-30 |
Scott Miller |
Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
|
|
EP1158985B1
(en)
|
1999-01-13 |
2011-12-28 |
Bayer HealthCare LLC |
OMEGA-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS
|
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
EP1140840B1
(en)
*
|
1999-01-13 |
2006-03-22 |
Bayer Pharmaceuticals Corp. |
-g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
US7928239B2
(en)
|
1999-01-13 |
2011-04-19 |
Bayer Healthcare Llc |
Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
|
|
ME00275B
(me)
|
1999-01-13 |
2011-02-10 |
Bayer Corp |
ω-KARBOKSIARIL SUPSTITUISANI DIFENIL KARBAMIDI KAO INHIBITORI RAF KINAZE
|
|
UA73492C2
(en)
|
1999-01-19 |
2005-08-15 |
|
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
CA2360934A1
(en)
|
1999-02-22 |
2000-08-31 |
Lin-Hua Zhang |
Polycyclo heterocyclic derivatives as antiinflammatory agents
|
|
JP2002539206A
(ja)
*
|
1999-03-12 |
2002-11-19 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
抗炎症剤としての芳香族複素環化合物
|
|
ATE278674T1
(de)
|
1999-03-12 |
2004-10-15 |
Boehringer Ingelheim Pharma |
Heterocyklischer harnstoff und verwandte verbindungen als entzündungshemmende mittel
|
|
JP2002539187A
(ja)
*
|
1999-03-17 |
2002-11-19 |
アストラゼネカ アクチボラグ |
アミド誘導体
|
|
CO5170528A1
(es)
*
|
1999-05-28 |
2002-06-27 |
Smithkline Beecham Corp |
Antagonistas de los receptores de la il-8 nistas del recpetor de la il-8
|
|
CO5190710A1
(es)
*
|
1999-06-15 |
2002-08-29 |
Smithkline Beecham Corp |
Antagonistas de un receptor de il-8 un receptor de il-8
|
|
CO5200760A1
(es)
*
|
1999-06-16 |
2002-09-27 |
Smithkline Beecham Corp |
Antagonistas del receptor de la il-8 ceptor il-8
|
|
CN1360582A
(zh)
*
|
1999-07-07 |
2002-07-24 |
阿斯特拉曾尼卡英国有限公司 |
喹唑啉衍生物
|
|
CA2374737C
(en)
|
1999-07-09 |
2008-02-12 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Novel process for synthesis of heteroaryl-substituted urea compounds
|
|
CA2380389A1
(en)
|
1999-07-26 |
2001-02-01 |
Banyu Pharmaceutical Co., Ltd. |
Biarylurea derivatives
|
|
CO5271663A1
(es)
*
|
1999-11-09 |
2003-04-30 |
Smithkline Beecham Corp |
Antagonistas del receptor il-8
|
|
EP1232150B1
(en)
|
1999-11-16 |
2007-10-10 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Urea derivatives as anti-inflammatory agents
|
|
US6525046B1
(en)
|
2000-01-18 |
2003-02-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
US6608052B2
(en)
|
2000-02-16 |
2003-08-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compounds useful as anti-inflammatory agents
|
|
WO2001064165A2
(en)
*
|
2000-03-01 |
2001-09-07 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
JP2004504270A
(ja)
*
|
2000-03-10 |
2004-02-12 |
スミスクライン・ビーチャム・コーポレイション |
Ｉｌ−８受容体アンタゴニスト
|
|
MY133845A
(en)
|
2000-03-10 |
2007-11-30 |
Smithkline Beecham Corp |
Il-8 receptor antagonists
|
|
JP2003527360A
(ja)
*
|
2000-03-14 |
2003-09-16 |
スミスクライン・ビーチャム・コーポレイション |
Ｉｌ−８受容体アンタゴニスト
|
|
CO5280089A1
(es)
*
|
2000-03-16 |
2003-05-30 |
Smithkline Beecham Corp |
Antagonistas del receptor il-8
|
|
UY26627A1
(es)
*
|
2000-03-24 |
2001-09-28 |
Smithkline Beecham Corp |
Antagonistas de receptores de il-8
|
|
EP1273571A4
(en)
*
|
2000-04-14 |
2003-05-02 |
Kureha Chemical Ind Co Ltd |
NITROGEN COMPOUNDS AND ANTIVIRAL MEDICATIONS CONTAINING THEM
|
|
CN1454204A
(zh)
*
|
2000-05-30 |
2003-11-05 |
史密丝克莱恩比彻姆公司 |
Il－8受体拮抗剂
|
|
EP1307190A4
(en)
*
|
2000-07-18 |
2007-08-22 |
Smithkline Beecham Corp |
USE OF IL-8 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VIRUS INFECTIONS
|
|
AU2001290852A1
(en)
*
|
2000-09-15 |
2002-03-26 |
Iconix Pharmaceuticals, Inc. |
Inhibitors of rho c
|
|
US7235576B1
(en)
|
2001-01-12 |
2007-06-26 |
Bayer Pharmaceuticals Corporation |
Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
JP2004520412A
(ja)
*
|
2001-01-16 |
2004-07-08 |
スミスクライン・ビーチャム・コーポレイション |
Ｉｌ−８受容体アンタゴニスト
|
|
DE60216229T2
(de)
*
|
2001-01-16 |
2007-10-04 |
Smithkline Beecham Corp. |
Il-8-rezeptorantagonisten
|
|
DE10109204A1
(de)
*
|
2001-02-26 |
2002-09-19 |
4Sc Ag |
Verbindungen zur Behandlung von Protozoen-Erkrankungen
|
|
EP1395548A1
(en)
|
2001-02-26 |
2004-03-10 |
4Sc Ag |
Derivatives of diphenylurea, diphenyloxalic acid diamide and diphenylsulfuric acid diamide and their use as medicaments
|
|
ITMI20010395A1
(it)
*
|
2001-02-27 |
2002-08-27 |
Dompe Spa |
Omega-amminoalchilammidi di acidi r-2-aril-propionici come inibitori della chemiotassi di cellule polimorfonucleate e mononucleate
|
|
US6646009B2
(en)
|
2001-02-28 |
2003-11-11 |
Temple University — Of Commonwealth System of Higher Education |
N-(aryl)-2-arylethenesulfonamides and therapeutic uses thereof
|
|
US7371763B2
(en)
*
|
2001-04-20 |
2008-05-13 |
Bayer Pharmaceuticals Corporation |
Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
|
|
US20040157818A1
(en)
*
|
2001-05-24 |
2004-08-12 |
Mikiro Yanaka |
Cxcr4-antagonistic drugs composed of nitrogen-containing compound
|
|
US20040038854A1
(en)
*
|
2001-07-16 |
2004-02-26 |
Dillon Susan B. |
Use of il-8 receptor antagonists in the treatment of virus infections
|
|
US6791892B2
(en)
*
|
2001-07-18 |
2004-09-14 |
Samsung Electronics Co., Ltd. |
Method of generating an initializing signal during power-up of semiconductor memory device
|
|
WO2003047579A1
(en)
*
|
2001-12-03 |
2003-06-12 |
Bayer Pharmaceuticals Corporation |
Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers
|
|
US20080108672A1
(en)
*
|
2002-01-11 |
2008-05-08 |
Bernd Riedl |
Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
|
|
ATE529406T1
(de)
*
|
2002-02-11 |
2011-11-15 |
Bayer Healthcare Llc |
Aryl-harnstoffe als kinase inhibitoren
|
|
WO2003068229A1
(en)
|
2002-02-11 |
2003-08-21 |
Bayer Pharmaceuticals Corporation |
Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
|
|
US20040023961A1
(en)
*
|
2002-02-11 |
2004-02-05 |
Bayer Corporation |
Aryl ureas with raf kinase and angiogenisis inhibiting activity
|
|
SI1478358T1
(sl)
|
2002-02-11 |
2013-09-30 |
Bayer Healthcare Llc |
Sorafenib tozilat za zdravljenje bolezni, značilnih po abnormalni angiogenezi
|
|
EP1480973B1
(en)
|
2002-02-25 |
2008-02-13 |
Boehringer Ingelheim Pharmaceuticals Inc. |
1,4-disubstituted benzofused cycloalkyl urea compounds useful in treating cytokine mediated diseases
|
|
EP1534284B1
(en)
*
|
2002-02-28 |
2011-07-27 |
Temple University - Of The Commonwealth System of Higher Education |
Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders
|
|
KR20030080509A
(ko)
*
|
2002-04-09 |
2003-10-17 |
주식회사 엘지생명과학 |
우레아, 티오우레아 및 설파마이드 유도체를 함유하는항균제 조성물
|
|
US20030236287A1
(en)
*
|
2002-05-03 |
2003-12-25 |
Piotrowski David W. |
Positive allosteric modulators of the nicotinic acetylcholine receptor
|
|
ATE372770T1
(de)
*
|
2002-08-01 |
2007-09-15 |
Neurosearch As |
Verbindungen nützlich in der behandlung von erkrankungen die auf anti-angiogenertherapie antworten
|
|
AU2003261974A1
(en)
*
|
2002-09-11 |
2004-04-30 |
Kureha Chemical Industry Company, Limited |
Amine compounds and use thereof
|
|
EP1402887A1
(en)
*
|
2002-09-18 |
2004-03-31 |
Jerini AG |
New compounds for the inhibition of undesired cell proliferation and use thereof
|
|
TW200418812A
(en)
*
|
2002-10-29 |
2004-10-01 |
Smithkline Beecham Corp |
IL-8 receptor antagonists
|
|
DE10251830A1
(de)
*
|
2002-11-07 |
2004-05-19 |
Wella Ag |
2-Amino-5-ethylphenol enthaltendes Mittel zum Färben von Keratinfasern
|
|
PT1565429E
(pt)
|
2002-11-21 |
2009-07-23 |
Neurosearch As |
Derivados de diaril-ureído e sua utilização médica
|
|
WO2004058683A2
(en)
*
|
2002-12-20 |
2004-07-15 |
Migenix Corp. |
Ligands of adenine nucleotide translocase (ant) and compositions and methods related thereto
|
|
WO2004058722A1
(en)
*
|
2002-12-24 |
2004-07-15 |
Arena Pharmaceuticals, Inc. |
Diarylamine and arylheteroarylamine pyrazole derivatives as modulators of 5ht2a
|
|
US7220768B2
(en)
*
|
2003-02-11 |
2007-05-22 |
Wyeth Holdings Corp. |
Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus
|
|
AU2004212633B2
(en)
*
|
2003-02-21 |
2010-12-09 |
ResMed Pty Ltd |
Nasal assembly
|
|
US7557129B2
(en)
|
2003-02-28 |
2009-07-07 |
Bayer Healthcare Llc |
Cyanopyridine derivatives useful in the treatment of cancer and other disorders
|
|
EP1457485A1
(en)
*
|
2003-03-14 |
2004-09-15 |
Dompé S.P.A. |
Sulfonic acids, their derivatives and pharmaceutical compositions containing them
|
|
US20050026844A1
(en)
*
|
2003-04-03 |
2005-02-03 |
Regents Of The University Of California |
Inhibitors for the soluble epoxide hydrolase
|
|
WO2005089380A2
(en)
|
2004-03-16 |
2005-09-29 |
The Regents Of The University Of California |
Reducing nephropathy with inhibitors of soluble epoxide hydrolase and epoxyeicosanoids
|
|
EP1636585B2
(en)
|
2003-05-20 |
2012-06-13 |
Bayer HealthCare LLC |
Diaryl ureas with kinase inhibiting activity
|
|
DE602004000260T2
(de)
*
|
2003-07-22 |
2006-08-24 |
Arena Pharmaceuticals, Inc., San Diego |
Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen
|
|
EP1663978B1
(en)
|
2003-07-23 |
2007-11-28 |
Bayer Pharmaceuticals Corporation |
Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
|
|
JP2007504202A
(ja)
|
2003-09-04 |
2007-03-01 |
ポセイドン ファーマシュティカルズ アクティーゼルスカブ |
心臓不整脈を治療するためのｅｒｇチャネル開口薬
|
|
WO2005023238A1
(en)
*
|
2003-09-04 |
2005-03-17 |
Poseidon Pharmaceuticals A/S |
Erg channel openers for the treatment of hyperexcitability-related neuronal diseases
|
|
TW200530236A
(en)
|
2004-02-23 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Heteroaryl phenylurea
|
|
JP3977411B2
(ja)
*
|
2004-03-10 |
2007-09-19 |
株式会社クレハ |
アミン系塩基性化合物とその用途
|
|
ATE548353T1
(de)
*
|
2004-03-23 |
2012-03-15 |
Arena Pharm Inc |
Verfahren zur herstellung von substituierte n- aryl-n'-ä3-(1h-pyrazol-5-yl)phenylü-harnstoffe and intermediate davon.
|
|
WO2005092843A1
(en)
*
|
2004-03-29 |
2005-10-06 |
Neurosearch A/S |
Novel urea derivatives and their medical use
|
|
EP2295426A1
(en)
|
2004-04-30 |
2011-03-16 |
Bayer HealthCare, LLC |
Substituted pyrazolyl urea derivatives useful in the treatment of cancer
|
|
US7550499B2
(en)
|
2004-05-12 |
2009-06-23 |
Bristol-Myers Squibb Company |
Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
CN1984899B
(zh)
|
2004-05-12 |
2011-07-27 |
先灵公司 |
Cxcr1和cxcr2趋化因子拮抗剂
|
|
AU2005245389A1
(en)
*
|
2004-05-12 |
2005-12-01 |
Bristol-Myers Squibb Company |
Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
FR2872159B1
(fr)
*
|
2004-06-28 |
2007-10-05 |
Merck Sante Soc Par Actions Si |
Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete
|
|
EA012119B1
(ru)
|
2004-08-12 |
2009-08-28 |
Пфайзер Инк. |
ПРОИЗВОДНЫЕ ТРИАЗОЛОПИРИДИНСУЛЬФАНИЛА В КАЧЕСТВЕ ИНГИБИТОРОВ p38 MAP КИНАЗЫ
|
|
BRPI0514379A
(pt)
*
|
2004-08-16 |
2008-06-10 |
Procter & Gamble |
compostos de 2-(amino ou amino substituìdo) fenol-5, 6-substituìdo, composições para tingimento contendo os mesmos, e uso das mesmas
|
|
EP1634573A1
(en)
*
|
2004-08-16 |
2006-03-15 |
The Procter and Gamble Company |
2-(Amino or substituted Amino)-5,6-substituted Phenol compounds, dyeing compositions containing them, and use thereof
|
|
EP1812008A4
(en)
*
|
2004-10-20 |
2008-10-29 |
Smithkline Beecham Corp |
ANTAGONISTS OF THE IL-8 RECEPTOR
|
|
JP2008517072A
(ja)
*
|
2004-10-20 |
2008-05-22 |
ザ レジェンツ オブ ザ ユニバーシティー オブ カリフォルニア |
可溶性エポキシド加水分解酵素の改良された阻害剤
|
|
JP2008517930A
(ja)
|
2004-10-21 |
2008-05-29 |
トランス テック ファーマ，インコーポレイテッド |
ＧａｌＲ１のアゴニストとしてのビススルホンアミド化合物、組成物、及び使用法
|
|
SA05260357B1
(ar)
|
2004-11-19 |
2008-09-08 |
ارينا فارماسيتو تيكالز ، أنك |
مشتقات 3_فينيل_بيرازول كمعدلات لمستقبل سيروتينين 5_ht2a مفيدة في علاج الاضطرابات المتعلقه به
|
|
US20080015223A1
(en)
*
|
2004-12-03 |
2008-01-17 |
Arena Pharmaceuticals, Inc. |
Pyrazole Derivatives as Modulators of the 5-Ht2a Serotonin Receptor Useful for the Treatment of Disorders Related Thereto
|
|
US20080200530A1
(en)
*
|
2005-01-19 |
2008-08-21 |
Unett David J |
Diaryl and Arylheteroaryl Urea Derivatives as Modulators of 5-Ht2a Serotonin Receptor Useful for the Prophylaxis or Treatment of Progressive Multifocal Leukoencephalopathy
|
|
WO2006078621A2
(en)
|
2005-01-19 |
2006-07-27 |
Bristol-Myers Squibb Company |
2-phenoxy-n- (1, 3 , 4-thiadizol-2-yl) pyridin-3-amine derivatives and related compounds as p2y1 receptor inhibitors for the treatment of thromboembolic disorders
|
|
US20090305321A1
(en)
*
|
2005-03-23 |
2009-12-10 |
Astrazeneca Ab |
Assays for Allosteric Modulators of G-Protein Coupled Receptors (GPCRs)
|
|
DE602006017694D1
(de)
|
2005-06-27 |
2010-12-02 |
Bristol Myers Squibb Co |
C-verknüpfte zyklische antagonisten des p2y1-rezeptors mit eignung bei der behandlung thrombotischer leiden
|
|
WO2007002634A1
(en)
|
2005-06-27 |
2007-01-04 |
Bristol-Myers Squibb Company |
Carbocycle and heterocycle antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
|
|
ATE502924T1
(de)
|
2005-06-27 |
2011-04-15 |
Bristol Myers Squibb Co |
Lineare harnstoffmimetika-antagonisten des p2y1- rezeptors zur behandlung von thromboseleiden
|
|
TW200726764A
(en)
|
2005-06-27 |
2007-07-16 |
Bristol Myers Squibb Co |
N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
GB0526255D0
(en)
|
2005-12-22 |
2006-02-01 |
Novartis Ag |
Organic compounds
|
|
TW200806641A
(en)
*
|
2006-01-25 |
2008-02-01 |
Synta Pharmaceuticals Corp |
Substituted aromatic compounds for inflammation and immune-related uses
|
|
US8097626B2
(en)
*
|
2006-04-21 |
2012-01-17 |
Glaxosmithkline Llc |
IL-8 receptor antagonists
|
|
PL2009992T3
(pl)
*
|
2006-04-21 |
2012-11-30 |
Glaxosmithkline Llc |
Antagoniści receptora IL-8
|
|
WO2007127930A2
(en)
*
|
2006-04-28 |
2007-11-08 |
Kansas State University Research Foundation |
Compounds affecting gap junction activity
|
|
JP5406018B2
(ja)
|
2006-05-18 |
2014-02-05 |
アリーナ ファーマシューティカルズ， インコーポレイテッド |
５−ｈｔ２ａセロトニンレセプターに関連する障害の処置に有用な５−ｈｔ２ａセロトニンレセプターのモジュレーターとしての１級アミン、およびその誘導体
|
|
SG171681A1
(en)
|
2006-05-18 |
2011-06-29 |
Arena Pharm Inc |
Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-ht2a serotonin receptor
|
|
CA2646076C
(en)
*
|
2006-05-18 |
2015-06-30 |
Arena Pharmaceuticals, Inc. |
Ethers, secondary amines and derivatives thereof as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
CL2007001829A1
(es)
|
2006-06-23 |
2008-01-25 |
Smithkline Beecham Corp |
P-toluensulfonato de n-[4-cloro-2-hidroxi-3-(piperazina-1-sulfonil)fenil]-n-(2-cloro-3-fluorofenil)urea;procedimiento de preparacion;composicion farmaceutica;combinacion farmaceutica;y uso en el tratamiento de una enfermedad mediada por la quiimioquina il-8, tales como asma y epoc.
|
|
TWI415845B
(zh)
|
2006-10-03 |
2013-11-21 |
Arena Pharm Inc |
用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
|
|
US7960569B2
(en)
|
2006-10-17 |
2011-06-14 |
Bristol-Myers Squibb Company |
Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
WO2008047067A1
(en)
*
|
2006-10-20 |
2008-04-24 |
University Court Of The University Of Edinburgh |
Treatment of inflammatory disease
|
|
JP5393677B2
(ja)
|
2007-08-15 |
2014-01-22 |
アリーナ ファーマシューティカルズ， インコーポレイテッド |
５−ＨＴ２Ａセロトニン受容体に関連した障害の治療のための５−ＨＴ２Ａセロトニン受容体のモジュレーターとしてのイミダゾ［１，２−ａ］ピリジン誘導体
|
|
KR20100087300A
(ko)
*
|
2007-09-28 |
2010-08-04 |
글락소스미스클라인 엘엘씨 |
글리코겐 포스포릴라아제 억제제 화합물 및 이의 약학적 조성물
|
|
US20110021538A1
(en)
*
|
2008-04-02 |
2011-01-27 |
Arena Pharmaceuticals, Inc. |
Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
|
|
CA2741731A1
(en)
*
|
2008-10-28 |
2010-06-03 |
Arena Pharmaceuticals, Inc. |
Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto
|
|
US9126946B2
(en)
|
2008-10-28 |
2015-09-08 |
Arena Pharmaceuticals, Inc. |
Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
|
|
WO2010092440A1
(en)
*
|
2009-02-16 |
2010-08-19 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Cxcr2 receptor antagonists for the treatment or the prevention of insulin resistance
|
|
WO2011022028A2
(en)
*
|
2009-05-18 |
2011-02-24 |
Tufts University |
Small molecule antagonists of phosphatidylinositol-3, 4, 5-triphosphate (pip3) and uses thereof
|
|
EP2512465A1
(en)
*
|
2009-12-17 |
2012-10-24 |
Galderma Research & Development |
Use of compounds in the treatment or prevention of skin disorders
|
|
WO2011075596A1
(en)
|
2009-12-18 |
2011-06-23 |
Arena Pharmaceuticals, Inc. |
Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
BRPI1004176A2
(pt)
*
|
2010-10-25 |
2015-08-11 |
Univ Rio De Janeiro |
Compostos aril e/ou hetero aril uréias funcionalizados; processo de síntese desses composto; composição farmacêutica contendo tais compostos e usos
|
|
US8648118B2
(en)
|
2010-12-17 |
2014-02-11 |
Boehringer Ingelheim International Gmbh |
Bicyclic ring system substituted amide functionalised phenols as medicaments
|
|
CA2834548C
(en)
|
2011-04-28 |
2021-06-01 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
EP2877444B1
(en)
|
2012-07-27 |
2020-09-02 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
WO2014080615A1
(ja)
*
|
2012-11-21 |
2014-05-30 |
日本曹達株式会社 |
非フェノール系化合物を用いた記録材料
|
|
US9914717B2
(en)
|
2012-12-20 |
2018-03-13 |
The Broad Institute, Inc. |
Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors
|
|
KR102216666B1
(ko)
|
2013-02-13 |
2021-02-17 |
오지 홀딩스 가부시키가이샤 |
감열 기록체
|
|
CN105283316B
(zh)
*
|
2013-05-22 |
2018-03-30 |
王子控股株式会社 |
热敏记录体
|
|
US10022355B2
(en)
|
2015-06-12 |
2018-07-17 |
Axovant Sciences Gmbh |
Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of REM sleep behavior disorder
|
|
EP3117835A1
(en)
*
|
2015-07-14 |
2017-01-18 |
Dompé farmaceutici s.p.a. |
Il-8 inhibitors for use in the treatment of certain urological disorders
|
|
BR112018000728A2
(pt)
|
2015-07-15 |
2018-09-04 |
Axovant Sciences Gmbh |
resumo método para a profilaxia e/ou tratamento de alucinações visuais em um sujeito com necessidade do mesmo
|
|
US10093617B1
(en)
*
|
2015-10-30 |
2018-10-09 |
Sumitomo Chemical Company, Limited |
Method for producing 2-amino-4-substituted phenol
|
|
JP7092356B2
(ja)
*
|
2016-06-22 |
2022-06-28 |
フーダン ユニヴァーシティ |
ビアリール尿素誘導体またはそれらの塩、およびそれらの調製方法および使用
|
|
CN107522641B
(zh)
*
|
2016-06-22 |
2020-05-05 |
复旦大学 |
联芳基脲类衍生物或其盐及其制备方法和用途
|
|
US11291641B2
(en)
*
|
2016-10-03 |
2022-04-05 |
The Children's Medical Center Corporation |
Prevention and treatment of diabetic nephropathy
|
|
EP3737362B1
(en)
|
2018-01-12 |
2025-10-15 |
Kdac Therapeutics, Inc. |
Combination of a selective histone deacetylase 3 (hdac3) inhibitor and an immunotherapy agent for the treatment of cancer
|
|
CN110698373A
(zh)
*
|
2019-11-07 |
2020-01-17 |
温州大学 |
N-（2-（甲硫基）苯基）乙酰胺类化合物的制备方法及其净化提纯方法
|
|
CN112321452B
(zh)
*
|
2020-09-11 |
2022-11-29 |
北京红惠新医药科技有限公司 |
厚朴酚衍生物、和厚朴酚衍生物及其盐酸盐、制备方法及应用
|
|
WO2025121190A1
(ja)
*
|
2023-12-08 |
2025-06-12 |
日産化学株式会社 |
重合体、樹脂組成物、液晶配向剤、樹脂被膜及び液晶配向膜
|
|
CN118063332A
(zh)
*
|
2024-02-29 |
2024-05-24 |
浙江鼎龙科技股份有限公司 |
一种2-羟基-4-乙基苯胺及其盐酸盐的制备方法
|