|
US6576239B1
(en)
|
1996-09-10 |
2003-06-10 |
The Burnham Institute |
Angiogenic homing molecules and conjugates derived therefrom
|
|
US6180084B1
(en)
|
1998-08-25 |
2001-01-30 |
The Burnham Institute |
NGR receptor and methods of identifying tumor homing molecules that home to angiogenic vasculature using same
|
|
GB9814527D0
(en)
*
|
1998-07-03 |
1998-09-02 |
Cyclacel Ltd |
Delivery system
|
|
ES2318906T3
(es)
|
1998-11-13 |
2009-05-01 |
Cyclacel Limited |
Vectores de transposicion derivados de helice 3 de homeodominio de antennapedia.
|
|
FR2786397B1
(fr)
*
|
1998-11-30 |
2003-01-10 |
Synt Em |
Vecteurs peptidiques de substances a travers la barriere hematoencephalique pour etre utilises dans le diagnostic ou la therapie d'une affection du snc
|
|
FR2786398B1
(fr)
*
|
1998-11-30 |
2002-12-27 |
Synt Em |
Composition pharmaceutique anti-cancereuse et anti-chimioresistance comprenant un agent anticancereux et au moins un peptide
|
|
US6833373B1
(en)
|
1998-12-23 |
2004-12-21 |
G.D. Searle & Co. |
Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
|
|
US6858598B1
(en)
|
1998-12-23 |
2005-02-22 |
G. D. Searle & Co. |
Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
|
|
US6528481B1
(en)
|
1999-02-16 |
2003-03-04 |
The Burnam Institute |
NG2/HM proteoglycan-binding peptides that home to angiogenic vasculature and related methods
|
|
US6380161B1
(en)
|
1999-06-21 |
2002-04-30 |
Inkine Pharmaceutical Company, Inc. |
Compositions for treating chemotherapy-resistant tumor cells and targeted chemotherapy compositions
|
|
HK1049443A1
(zh)
*
|
1999-11-12 |
2003-05-16 |
Angiotech Pharmaceuticals, Inc. |
用放射活性疗法和细胞循环抑制剂联合治疗疾病的组合物和方法
|
|
AU767394C
(en)
|
1999-12-29 |
2005-04-21 |
Immunogen, Inc. |
Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
|
|
AU4267700A
(en)
*
|
2000-01-13 |
2001-07-19 |
Academia Sinica |
Application of somatostatin analogs to specific delivery of anti-tumor drugs into tumor cells
|
|
JP2004517034A
(ja)
*
|
2000-04-26 |
2004-06-10 |
バイオシンセマ インコーポレーテッド |
（神経）ペプチド結合ｒｇｄ（ａｒｇ−ｇｌｙ−ａｓｐ）
|
|
US7420030B2
(en)
|
2000-09-08 |
2008-09-02 |
The Board Of Regents Of The University Of Texas System |
Aminopeptidase A (APA) targeting peptides for the treatment of cancer
|
|
US20040170955A1
(en)
|
2000-09-08 |
2004-09-02 |
Wadih Arap |
Human and mouse targeting peptides identified by phage display
|
|
US7452964B2
(en)
|
2001-09-07 |
2008-11-18 |
Board Of Regents, The University Of Texas System |
Compositions and methods of use of targeting peptides against placenta and adipose tissues
|
|
KR100420007B1
(ko)
*
|
2001-04-25 |
2004-03-02 |
노영쇠 |
안트라사이클린 유도체 및 이를 포함하는 항암제
|
|
BR0212897A
(pt)
*
|
2001-09-21 |
2004-08-24 |
Univ Tulane |
Conjugados de análogos de somatostatina ou bombesina diagnóstica ou terapêutica e usos dos mesmos
|
|
WO2003072754A2
(en)
*
|
2002-02-27 |
2003-09-04 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Conjugates of ligand, linker and cytotoxic agent and related compositions and methods of use
|
|
US7771727B2
(en)
|
2002-03-01 |
2010-08-10 |
The Administrators Of The Tulane Educational Fund |
Conjugates of therapeutic or cytotoxic agents and biologically active peptides
|
|
US7544767B2
(en)
|
2002-04-05 |
2009-06-09 |
Burnham Institute For Medical Research |
HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells
|
|
JP5000848B2
(ja)
*
|
2002-05-21 |
2012-08-15 |
第一三共株式会社 |
グレリン含有医薬組成物
|
|
CN101134119A
(zh)
|
2002-05-24 |
2008-03-05 |
血管技术国际股份公司 |
用于涂覆医用植入物的组合物和方法
|
|
US8313760B2
(en)
|
2002-05-24 |
2012-11-20 |
Angiotech International Ag |
Compositions and methods for coating medical implants
|
|
AU2003275263A1
(en)
|
2002-09-26 |
2004-04-19 |
Angiotech International Ag |
Perivascular wraps
|
|
WO2004060346A2
(en)
|
2002-12-30 |
2004-07-22 |
Angiotech International Ag |
Drug delivery from rapid gelling polymer composition
|
|
US20040202666A1
(en)
*
|
2003-01-24 |
2004-10-14 |
Immunomedics, Inc. |
Anti-cancer anthracycline drug-antibody conjugates
|
|
US20050043215A1
(en)
|
2003-02-19 |
2005-02-24 |
Tamara Minko |
Complex drug delivery composition and method for treating cancer
|
|
AU2007221964B2
(en)
*
|
2003-04-22 |
2008-12-11 |
Ipsen Pharma S.A.S. |
Peptide vectors
|
|
US8709998B2
(en)
*
|
2003-04-22 |
2014-04-29 |
Ipsen Pharma S.A.S. |
Peptide vectors
|
|
US7097993B2
(en)
|
2003-06-25 |
2006-08-29 |
Wisconsin Alumni Research Foundation |
Method for identifying an agent that modulates type 1 phosphatidylinositol phosphate kinase isoform β661 activity
|
|
WO2005086951A2
(en)
*
|
2004-03-10 |
2005-09-22 |
Threshold Pharmaceuticals, Inc. |
Hypoxia-activated anti-cancer agents
|
|
US20070060534A1
(en)
*
|
2005-06-30 |
2007-03-15 |
Threshold Pharmaceuticals, Inc. |
Anthracycline analogs
|
|
EP1900742A1
(en)
|
2006-09-07 |
2008-03-19 |
AEterna Zentaris GmbH |
Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof
|
|
HRP20160631T1
(hr)
*
|
2006-09-06 |
2016-07-15 |
Æterna Zentaris Gmbh |
Konjugati disorazola i njihovi derivati sa staničnovezajućim molekulama, novi derivati disorazola, postupci njihove pripreme i njihove uporabe
|
|
WO2008100591A2
(en)
*
|
2007-02-14 |
2008-08-21 |
The General Hospital Corporation |
Modulation of nitric oxide signaling to normalize tumor vasculature
|
|
RU2377247C2
(ru)
*
|
2007-12-27 |
2009-12-27 |
Федеральное государственное образовательное учреждение высшего профессионального образования Санкт-Петербургский государственный университет |
Молекулярный конъюгат на основе синтетических аналогов люлиберина и его применение в качестве средства доставки днк в клетки гормон-чувствительных опухолей (варианты)
|
|
EP2240495B1
(en)
*
|
2008-02-01 |
2015-07-15 |
Genentech, Inc. |
Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
|
|
EP2277884B1
(en)
*
|
2008-04-11 |
2017-08-23 |
Tianjin Hemay Oncology Pharmaceutical Co., Ltd |
Anthracycline antibiotic derivatives with high activity, preparation methods and uses thereof
|
|
BRPI0911647A2
(pt)
*
|
2008-04-11 |
2015-10-13 |
Tianjin Hemay Bio Tech Co Ltd |
compostos derivados de antibióticos de antraciclina com alta atividade, métodos de preeparação e uso dos mesmos.
|
|
AU2009270988A1
(en)
*
|
2008-07-15 |
2010-01-21 |
Genentech, Inc. |
Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
|
|
MX2011008774A
(es)
|
2009-02-20 |
2011-10-24 |
Ipsen Pharma Sas |
Conjugados citotoxicos que tienen un compuesto de unión de receptores de neuropeptidos y.
|
|
CN102050856B
(zh)
*
|
2009-11-03 |
2014-04-30 |
天津和美生物技术有限公司 |
具有高活性的表阿霉素的衍生物及其制备和应用
|
|
EP2646456B1
(en)
|
2010-12-02 |
2015-01-21 |
Nerviano Medical Sciences S.r.l. |
Process for the preparation of morpholinyl anthracycline derivatives
|
|
CN105198966B
(zh)
*
|
2014-06-26 |
2019-06-21 |
中国人民解放军军事医学科学院毒物药物研究所 |
GnRH类似物-细胞毒分子缀合物、其制备方法及用途
|
|
CN110478495A
(zh)
|
2014-06-30 |
2019-11-22 |
塔弗达治疗有限公司 |
靶向缀合物及其颗粒和制剂
|
|
EP3045540A1
(en)
|
2015-01-19 |
2016-07-20 |
Æterna Zentaris GmbH |
Enzymatic process for the regioselective manufacturing of N-Fmoc-doxorubicin-14-O-dicarboxylic acid mono esters
|
|
CN108473538B
(zh)
|
2015-10-28 |
2022-01-28 |
塔弗达治疗有限公司 |
Sstr靶向缀合物及其颗粒和制剂
|
|
US10450340B2
(en)
|
2017-02-16 |
2019-10-22 |
Monopar Therapeutics Inc. |
3′-deamino-3′-(2″-pyrroline-1″-yl)-5-imino-13-deoxyanthracyclines and methods of preparation
|
|
AU2019469641B2
(en)
*
|
2018-11-13 |
2025-04-03 |
Provincial Health Services Authority |
Radiolabeled bombesin-derived compounds for in vivo imaging of gastrin-releasing peptide receptor (GRPR) and treatment of GRPR-related disorders
|
|
AU2023239751A1
(en)
|
2022-03-25 |
2024-09-05 |
Provincial Health Services Authority |
Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (grpr) and treatment of grpr-related disorders
|