JOP20220116A1 - اللقاحات المستندة إلى الطافر calr وjak2 واستخداماتها - Google Patents

اللقاحات المستندة إلى الطافر calr وjak2 واستخداماتها

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Publication number
JOP20220116A1
JOP20220116A1 JOP/2022/0116A JOP20220116A JOP20220116A1 JO P20220116 A1 JOP20220116 A1 JO P20220116A1 JO P20220116 A JOP20220116 A JO P20220116A JO P20220116 A1 JOP20220116 A1 JO P20220116A1
Authority
JO
Jordan
Prior art keywords
mutant
calr
jak2
methods
vaccines based
Prior art date
Application number
JOP/2022/0116A
Other languages
English (en)
Inventor
Vinod Krishna
Ricardo Attar
Selina Khan
Jason Dehart
Roland Zahn
Barbara Sanders
Manuel Alejandro Sepulveda
Jenifer Lum
Christian Maine
Patrick Wilkinson
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of JOP20220116A1 publication Critical patent/JOP20220116A1/ar

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    • A61K39/001162—Kinases, e.g. Raf or Src
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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Abstract

تتوفر لقاحات وعديدات ببتيد وعديدات نوكليوتيد مستندة إلى تسلسلات الطافر CALR وJAK2 والنواقل والخلايا العائلة والفيروسات وطرق تحضيرها واستخدامها. يوفر الكشف أيضًا طرق تحفيز الاستجابة المناعية وطرق العلاج والوقاية وتقليل مخاطر ظهور أو تأخير ظهور حالة سريرية تتسم بتعبير طافر 9 لإكسون JAK2V617F أو CALR، أو الطافر 9 لإكسون كل من JAK2V617F وCALR، حيث تتألف الطريقة من مجموعة من طرق الإعطاء لأي من التركيبات التي تشتمل على عديدات النوكليوتيد أو عديدات الببتيد أو النواقل التي يتم الكشف عنها هنا.
JOP/2022/0116A 2019-11-18 2020-11-13 اللقاحات المستندة إلى الطافر calr وjak2 واستخداماتها JOP20220116A1 (ar)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962936841P 2019-11-18 2019-11-18
US201962936846P 2019-11-18 2019-11-18
PCT/IB2020/060713 WO2021099906A1 (en) 2019-11-18 2020-11-13 Vaccines based on mutant calr and jak2 and their uses

Publications (1)

Publication Number Publication Date
JOP20220116A1 true JOP20220116A1 (ar) 2023-01-30

Family

ID=73544235

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2022/0116A JOP20220116A1 (ar) 2019-11-18 2020-11-13 اللقاحات المستندة إلى الطافر calr وjak2 واستخداماتها

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Country Link
US (1) US12018289B2 (ar)
EP (1) EP4061405A1 (ar)
JP (1) JP2023509571A (ar)
KR (1) KR20220115569A (ar)
CN (1) CN114980920A (ar)
AU (1) AU2020385683A1 (ar)
BR (1) BR112022009598A2 (ar)
CA (1) CA3161800A1 (ar)
CL (1) CL2022001298A1 (ar)
CO (1) CO2022008493A2 (ar)
CR (1) CR20220220A (ar)
DO (1) DOP2022000103A (ar)
EC (1) ECSP22048779A (ar)
IL (1) IL293051A (ar)
JO (1) JOP20220116A1 (ar)
MX (1) MX2022005980A (ar)
PE (1) PE20221182A1 (ar)
TW (1) TW202120533A (ar)
UY (1) UY38961A (ar)
WO (1) WO2021099906A1 (ar)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230285548A1 (en) * 2021-12-16 2023-09-14 Janssen Biotech, Inc. Vaccines based on mutant calr and jak2 and their uses

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