IT1197713B - Dicloro-derivati della serie del 16 alfa-metil pregnano,procedimento per la produzione,loro applicazione come medicamenti e composizioni che li contengono - Google Patents
Dicloro-derivati della serie del 16 alfa-metil pregnano,procedimento per la produzione,loro applicazione come medicamenti e composizioni che li contengonoInfo
- Publication number
- IT1197713B IT1197713B IT48990/83A IT4899083A IT1197713B IT 1197713 B IT1197713 B IT 1197713B IT 48990/83 A IT48990/83 A IT 48990/83A IT 4899083 A IT4899083 A IT 4899083A IT 1197713 B IT1197713 B IT 1197713B
- Authority
- IT
- Italy
- Prior art keywords
- pregnate
- alfa
- medications
- dichloro
- derivatives
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/13—Monohydroxylic alcohols containing saturated rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C68/00—Preparation of esters of carbonic or haloformic acids
- C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
- C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
- C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Rheumatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8216668A FR2533928A1 (fr) | 1982-10-05 | 1982-10-05 | Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1197713B true IT1197713B (it) | 1988-12-06 |
Family
ID=9277977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48990/83A IT1197713B (it) | 1982-10-05 | 1983-09-19 | Dicloro-derivati della serie del 16 alfa-metil pregnano,procedimento per la produzione,loro applicazione come medicamenti e composizioni che li contengono |
Country Status (22)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2561919B1 (fr) * | 1984-04-03 | 1986-12-19 | Roussel Uclaf | Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon |
| GB8512738D0 (en) * | 1984-09-04 | 1985-06-26 | Gen Electric | Silylation method |
| WO1999061055A1 (en) | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
| US7247607B2 (en) * | 2001-11-08 | 2007-07-24 | Green & Clean, Inc. | Active soluble cleaning composite of natural state using soybean fatty acids and the making method thereof |
| DK1889198T3 (da) | 2005-04-28 | 2015-02-09 | Proteus Digital Health Inc | Farma-informatiksystem |
| JP2009508494A (ja) | 2005-09-16 | 2009-03-05 | ラプトール ファーマシューティカル インコーポレイテッド | Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用 |
| CA2969926C (en) | 2009-02-20 | 2018-05-15 | 2-Bbb Medicines B.V. | Glutathione-based drug delivery system |
| IL295075A (en) | 2009-05-06 | 2022-09-01 | Laboratory Skin Care Inc | Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2342738A1 (fr) * | 1976-03-02 | 1977-09-30 | Roussel Uclaf | Nouveaux derives halogenes de la serie du 16a-methyl pregnane |
| FR2381065A2 (fr) * | 1977-02-22 | 1978-09-15 | Roussel Uclaf | Nouveaux derives halogenes de la serie du 16 a-methyl pregnane |
| FR2462443A1 (fr) * | 1979-07-26 | 1981-02-13 | Roussel Uclaf | Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament |
-
1982
- 1982-10-05 FR FR8216668A patent/FR2533928A1/fr active Granted
-
1983
- 1983-07-20 SE SE8304062A patent/SE447388B/sv not_active IP Right Cessation
- 1983-07-27 NO NO832738A patent/NO157864C/no unknown
- 1983-09-03 ZA ZA836538A patent/ZA836538B/xx unknown
- 1983-09-15 US US06/532,739 patent/US4515787A/en not_active Expired - Fee Related
- 1983-09-19 IT IT48990/83A patent/IT1197713B/it active
- 1983-09-28 MA MA20132A patent/MA19909A1/fr unknown
- 1983-09-30 AU AU19824/83A patent/AU563739B2/en not_active Ceased
- 1983-10-04 FI FI833602A patent/FI77668C/fi not_active IP Right Cessation
- 1983-10-04 BE BE0/211641A patent/BE897906A/fr not_active IP Right Cessation
- 1983-10-04 IE IE2337/83A patent/IE56022B1/en not_active IP Right Cessation
- 1983-10-04 HU HU833444A patent/HU190506B/hu not_active IP Right Cessation
- 1983-10-04 ES ES526212A patent/ES8405812A1/es not_active Expired
- 1983-10-04 CA CA000438264A patent/CA1203234A/fr not_active Expired
- 1983-10-04 CH CH5395/83A patent/CH659251A5/fr not_active IP Right Cessation
- 1983-10-04 DK DK456483A patent/DK164062C/da not_active IP Right Cessation
- 1983-10-04 GB GB08326527A patent/GB2127827B/en not_active Expired
- 1983-10-05 AT AT0352783A patent/AT385996B/de not_active IP Right Cessation
- 1983-10-05 DE DE19833336292 patent/DE3336292A1/de active Granted
- 1983-10-05 NL NL8303409A patent/NL8303409A/nl not_active Application Discontinuation
- 1983-10-05 OA OA58129A patent/OA07558A/xx unknown
- 1983-10-05 JP JP58185211A patent/JPS59116300A/ja active Granted
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT8347820A0 (it) | Derivati di 3-cheto delta 4,9 19nor-steroidi,procedimento per la loro preparazione,loro impiego come medicamenti,composizioni che li con tengono ed intermedi ottenuti | |
| IT1164634B (it) | Derivati cefalosporinici e composizioni antibatteriche che li contengono,nonche' procedimento per la loro produzione | |
| IT1098253B (it) | Propenil-ammine,procedimenti per la loro produzione,e composizioni farmaceutiche che le contengono | |
| IT1195297B (it) | Composti xantati antivirali,procedimento per la loro produzione e composizioni farmaceutiche che li contengono | |
| IT1203791B (it) | Derivati del morfinano e della morfina,loro preparazione,loro impiego come medicamenti e e le composizioni farmaceutiche che li contengono | |
| IT1167123B (it) | Benzoazacicloalchilspiro-imidazolidine,procedimento per prepararle e composizioni farmaceutiche che le contengono | |
| IT1213257B (it) | 5-pirimidincarbossammidi e tiocarbossammidi processo per la loro produzione e composizioni farmaceutiche contenenti le stesse | |
| IT1170314B (it) | Composizione antivirale contenente isotiosemicarbazoni e relativo procadimento di produzione ed applicazione | |
| IT7949530A0 (it) | Procedimento per la produzione di 14,15-derivati metilenici della serie d'estrano | |
| IT1197713B (it) | Dicloro-derivati della serie del 16 alfa-metil pregnano,procedimento per la produzione,loro applicazione come medicamenti e composizioni che li contengono | |
| IL68576A0 (en) | Azepinoindoles,their production and pharmaceutical compositions containing them | |
| IT8319914A0 (it) | Enzimi fibrinolitici,procedimenti per la loro produzione e composizioni farmaceutiche che li contengono | |
| IT8148567A0 (it) | Derivati della benzoguanammina procedimento per la loro produzione e composizioni farmaceutiche che licontengono | |
| IL63429A0 (en) | Guanylated aminoglycosides,their production and pharmaceutical compositions containing them | |
| IT1191050B (it) | 2(1-alchil-5-nitro)-imidazolil-1-(2-idrossi-5-alchil)-fenil-carbinoli,loro metodo di preparazione e composizioni farmaceutiche che li contengono | |
| IT8348537A0 (it) | Procedimento per la produzione di 1,2-dicloroetano | |
| IT1164226B (it) | Penem derivati,loro preparazione e composizioni che li contengono | |
| IT1213223B (it) | Procedimento di preparazionedi derivati della serie del 17 alfa-idrossi-19-nor-progesterone. | |
| IL67813A0 (en) | Benzothienylallylamines,their production and pharmaceutical compositions containing them | |
| IT1200163B (it) | 8alfa-acilamminoergoline, loro preparazione e composizioni farmaceutiche che le contengono | |
| IT1200079B (it) | Derivati della naftossazina, loro preparazione, loro applicazione come medicamenti e composizioni farmaceutiche che li contengono | |
| IT1138155B (it) | Composti citostatici,procedimento per la loro preparazione e composizioni farmaceutiche contenenti gli stessi | |
| IT8448800A0 (it) | Amminociclopentani, composizioni farmaceutiche che li contengono eprocedimento per la loro preparazione | |
| IT8348067A0 (it) | Cianoguanidine, procedimento per ottenerle e composizioni farmaceutiche che le contengono | |
| IT1235761B (it) | Derivati biciclici del catecolo, procedimento per la loro preparazione e composizioni terapeutiche che li contengono |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19930914 |