IT1152505B - Derivati di una tetrazina - Google Patents

Derivati di una tetrazina

Info

Publication number
IT1152505B
IT1152505B IT22938/82A IT2293882A IT1152505B IT 1152505 B IT1152505 B IT 1152505B IT 22938/82 A IT22938/82 A IT 22938/82A IT 2293882 A IT2293882 A IT 2293882A IT 1152505 B IT1152505 B IT 1152505B
Authority
IT
Italy
Prior art keywords
tetrazine
derivatives
Prior art date
Application number
IT22938/82A
Other languages
English (en)
Italian (it)
Other versions
IT8222938A0 (it
Inventor
Edward Lunt
Malcolm Francis Graham Stevens
Robert Stone
Kenneth Robert Harr Wooldridge
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of IT8222938A0 publication Critical patent/IT8222938A0/it
Application granted granted Critical
Publication of IT1152505B publication Critical patent/IT1152505B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT22938/82A 1981-08-24 1982-08-23 Derivati di una tetrazina IT1152505B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
IT8222938A0 IT8222938A0 (it) 1982-08-23
IT1152505B true IT1152505B (it) 1987-01-07

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22938/82A IT1152505B (it) 1981-08-24 1982-08-23 Derivati di una tetrazina

Country Status (29)

Country Link
JP (1) JPS5843975A (pt)
KR (1) KR890000094B1 (pt)
AT (1) AT380256B (pt)
AU (1) AU571430B2 (pt)
BE (1) BE894175A (pt)
CA (1) CA1197247A (pt)
CH (1) CH655114A5 (pt)
DE (2) DE19975037I2 (pt)
DK (1) DK161147C (pt)
ES (1) ES8400438A1 (pt)
FI (1) FI73434C (pt)
FR (1) FR2511679A1 (pt)
GB (1) GB2104522B (pt)
GE (1) GEP19960641B (pt)
GR (1) GR76863B (pt)
HU (1) HU186107B (pt)
IE (1) IE53408B1 (pt)
IL (1) IL66606A (pt)
IT (1) IT1152505B (pt)
LT (1) LT2436B (pt)
LU (1) LU84347A1 (pt)
LV (2) LV5511A3 (pt)
NL (2) NL192739C (pt)
NZ (1) NZ201668A (pt)
OA (1) OA07174A (pt)
SE (1) SE448543B (pt)
SU (1) SU1447284A3 (pt)
UA (1) UA5971A1 (pt)
ZA (1) ZA826120B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
FR2531958B1 (fr) * 1982-08-17 1986-10-31 May & Baker Ltd Nouveaux derive
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
US7615632B2 (en) 2003-12-30 2009-11-10 Chemagis Ltd. Crystalline forms of temozolomide
JP5475235B2 (ja) 2005-01-21 2014-04-16 アステックス・セラピューティクス・リミテッド 医薬化合物
PE20080695A1 (es) 2006-04-27 2008-06-28 Banyu Pharma Co Ltd Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
JPWO2009054332A1 (ja) 2007-10-23 2011-03-03 萬有製薬株式会社 ピリドン置換ジヒドロピラゾロピリミジノン誘導体
PE20091101A1 (es) * 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
CA2744560A1 (en) * 2008-11-24 2010-05-27 Reliance Life Sciences Pvt. Ltd. Process for the preparation of tetrazine derivatives
US8481503B2 (en) 2009-03-06 2013-07-09 Merck Sharp & Dohme Corp. Combination cancer therapy with an AKT inhibitor and other anticancer agents
JP2012530775A (ja) 2009-06-23 2012-12-06 ファーミノックス リミテッド ３−置換−８−置換−３Ｈ−イミダゾ［５，１−ｄ］［１，２，３，５−テトラジン−４−オン化合物及びその使用
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
EP2766041B1 (en) 2011-10-12 2018-12-05 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
KR20230042756A (ko) 2016-03-15 2023-03-29 오리존 지노믹스 에스.에이. 고형 종양의 치료에 사용하기 위한 lsd1 억제제의 조합물
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Also Published As

Publication number Publication date
KR890000094B1 (ko) 1989-03-07
LV5511A3 (lv) 1994-03-10
OA07174A (fr) 1984-04-30
IE53408B1 (en) 1988-11-09
NL990010I2 (nl) 1999-09-01
NL8203286A (nl) 1983-03-16
FI822921L (fi) 1983-02-25
ES515176A0 (es) 1983-11-01
DE19975037I2 (de) 2001-06-13
GB2104522B (en) 1985-06-12
LU84347A1 (fr) 1983-06-07
DK377882A (da) 1983-02-25
GB2104522A (en) 1983-03-09
CH655114A5 (fr) 1986-03-27
IT8222938A0 (it) 1982-08-23
NL192739C (nl) 1998-01-06
NZ201668A (en) 1985-08-16
DE3231255A1 (de) 1983-03-03
LT2436B (lt) 1994-02-15
IE822026L (en) 1983-02-24
LV5621A3 (lv) 1994-05-10
AU571430B2 (en) 1988-04-21
JPS5843975A (ja) 1983-03-14
FI73434B (fi) 1987-06-30
SE8204817D0 (sv) 1982-08-23
UA5971A1 (uk) 1994-12-29
HU186107B (en) 1985-06-28
FR2511679B1 (pt) 1985-02-01
DK161147B (da) 1991-06-03
ZA826120B (en) 1983-07-27
JPH045029B2 (pt) 1992-01-30
SU1447284A3 (ru) 1988-12-23
NL192739B (nl) 1997-09-01
DE3231255C2 (pt) 1992-02-27
FI73434C (fi) 1987-10-09
SE448543B (sv) 1987-03-02
DK161147C (da) 1991-11-18
AT380256B (de) 1986-05-12
FR2511679A1 (fr) 1983-02-25
GEP19960641B (en) 1996-11-15
ES8400438A1 (es) 1983-11-01
SE8204817L (sv) 1983-02-25
IL66606A (en) 1987-07-31
FI822921A0 (fi) 1982-08-23
AU8749382A (en) 1983-03-03
IL66606A0 (en) 1982-12-31
GR76863B (pt) 1984-09-04
BE894175A (fr) 1983-02-23
ATA319182A (de) 1985-09-15
CA1197247A (fr) 1985-11-26
NL990010I1 (nl) 1999-07-01
KR840001175A (ko) 1984-03-28

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Legal Events

Date Code Title Description
MED Supplementary protection certificate for pharmaceutical products: no action taken

Free format text: CCP 663, 19990709; CANCER RESEARCH CAMPAIGN TECHN.LTD.

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 663, 19990709; CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970829