IN2014MN01298A - - Google Patents
Info
- Publication number
- IN2014MN01298A IN2014MN01298A IN1298MUN2014A IN2014MN01298A IN 2014MN01298 A IN2014MN01298 A IN 2014MN01298A IN 1298MUN2014 A IN1298MUN2014 A IN 1298MUN2014A IN 2014MN01298 A IN2014MN01298 A IN 2014MN01298A
- Authority
- IN
- India
- Prior art keywords
- hereinafter
- vector
- relates
- present
- microorganisms
- Prior art date
Links
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 244000005700 microbiome Species 0.000 abstract 2
- 108010055400 Aspartate kinase Proteins 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 108010053763 Pyruvate Carboxylase Proteins 0.000 abstract 1
- 102100039895 Pyruvate carboxylase, mitochondrial Human genes 0.000 abstract 1
- 108091081024 Start codon Proteins 0.000 abstract 1
- 102000014701 Transketolase Human genes 0.000 abstract 1
- 108010043652 Transketolase Proteins 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
- C12Y202/01—Transketolases and transaldolases (2.2.1)
- C12Y202/01001—Transketolase (2.2.1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
- C12Y207/02004—Aspartate kinase (2.7.2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
- C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
- C12Y604/01001—Pyruvate carboxylase (6.4.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/101—Plasmid DNA for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20110139527 | 2011-12-21 | ||
| PCT/KR2012/011328 WO2013095071A2 (ko) | 2011-12-21 | 2012-12-21 | Ｌ-라이신 생산능을 갖는 미생물을 이용하여 ｌ-라이신을 생산하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN01298A true IN2014MN01298A (de) | 2015-07-03 |
Family
ID=48669667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1298MUN2014 IN2014MN01298A (de) | 2011-12-21 | 2012-12-21 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9593354B2 (de) |
| EP (2) | EP2796555B1 (de) |
| JP (2) | JP6082025B2 (de) |
| KR (3) | KR101483344B1 (de) |
| CN (4) | CN109251934B (de) |
| BR (2) | BR112014015215B1 (de) |
| CA (1) | CA2860252C (de) |
| DK (1) | DK2796555T3 (de) |
| ES (1) | ES2696173T3 (de) |
| IN (1) | IN2014MN01298A (de) |
| MX (2) | MX353594B (de) |
| MY (1) | MY171302A (de) |
| PL (1) | PL2796555T3 (de) |
| RU (3) | RU2588665C2 (de) |
| WO (1) | WO2013095071A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109251934B (zh) * | 2011-12-21 | 2023-07-18 | Cj第一制糖株式会社 | 利用具有产生l-赖氨酸能力的微生物产生l-赖氨酸的方法 |
| KR101755767B1 (ko) | 2014-09-05 | 2017-07-10 | 씨제이제일제당 (주) | L-라이신 생산능이 향상된 미생물 및 이를 이용한 l-라이신 생산방법 |
| KR101793328B1 (ko) * | 2015-07-03 | 2017-11-03 | 씨제이제일제당 (주) | Ｌ-라이신 생산능을 갖는 미생물 및 이를 이용한 ｌ-라이신 생산 방법 |
| WO2018032240A1 (en) * | 2016-08-15 | 2018-02-22 | Cathay R&D Center Co., Ltd. | Control of biofilm dispersal for the production of amino acids or amino acid-derived products |
| KR101863456B1 (ko) * | 2016-11-15 | 2018-06-01 | 씨제이제일제당 (주) | L-라이신을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-라이신의 생산방법 |
| DE102017004751A1 (de) * | 2017-05-18 | 2018-11-22 | Forschungszentrum Jülich GmbH | Pyruvatcarboxylase und für die Pyruvatcarboxylase kodierende DNA, Plasmid enthaltend die DNA, sowie Mikroorganismus zur Produktion und verfahren zur Herstellung von Produkten, deren Bioynthese Oxalacetat als Vorstufe beeinhaltet und Chromosom |
| EP3456833A1 (de) | 2017-09-18 | 2019-03-20 | Evonik Degussa GmbH | Methode zur fermentativen production von l-aminosäuren |
| EP3467099A1 (de) | 2017-10-05 | 2019-04-10 | Evonik Degussa GmbH | Verfahren zur fermentativen herstellung von l-aminosäuren |
| EP3498853A1 (de) | 2017-12-14 | 2019-06-19 | Evonik Degussa GmbH | Verfahren zur fermentativen herstellung von l-lysin |
| KR101915433B1 (ko) * | 2018-02-13 | 2018-11-05 | 씨제이제일제당 (주) | 시트레이트 신타아제 (Citrate synthase)의 활성이 약화된 변이형 폴리펩타이드 및 이를 이용한 L-아미노산 생산방법 |
| EP3594355A1 (de) | 2018-07-12 | 2020-01-15 | Evonik Operations GmbH | Verfahren zur fermentativen herstellung von l-lysin |
| EP3599282B1 (de) | 2018-07-24 | 2021-03-17 | Evonik Operations GmbH | Verfahren zur fermentativen herstellung von l-lysin |
| RU2019128538A (ru) | 2018-09-26 | 2021-03-11 | Эвоник Оперейшенс ГмбХ | Способ ферментативного получения l-лизина |
| EP3660158A1 (de) | 2018-11-29 | 2020-06-03 | Evonik Operations GmbH | Verfahren zur fermentativen herstellung von l-lysin |
| CN109554322B (zh) * | 2018-12-03 | 2020-08-04 | 江南大学 | 一种高产l-苏氨酸的重组大肠杆菌及其构建方法 |
| EP3670525A1 (de) | 2018-12-18 | 2020-06-24 | Evonik Operations GmbH | Verfahren zur fermentativen herstellung von l-lysin unter verwendung von c.-glutamicum-stämmen mit einem mutierten kup-transporter |
| US10829746B2 (en) | 2019-01-23 | 2020-11-10 | Evonik Operations Gmbh | Method for the fermentative production of L-lysine |
| WO2021048353A1 (en) | 2019-09-11 | 2021-03-18 | Evonik Operations Gmbh | Coryneform bacteria with a heterologous threonine transporter and their use in the production of l-threonine |
| CN112877269B (zh) | 2020-01-15 | 2021-12-24 | 中国科学院天津工业生物技术研究所 | 生产赖氨酸的微生物以及赖氨酸的生产方法 |
| WO2022050524A1 (ko) * | 2020-09-03 | 2022-03-10 | 대상 주식회사 | L-라이신 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-라이신의 생산 방법 |
| CA3217309A1 (en) * | 2021-04-30 | 2022-11-03 | Cj Cheiljedang Corporation | Corynebacterium glutamicum variant having improved l-lysine production ability, and method for producing l-lysine by using same |
| MX2023012873A (es) * | 2021-04-30 | 2024-01-24 | Cj Cheiljedang Corp | Variante de corynebacterium glutamicum con capacidad mejorada de producción de l-lisina y procedimiento para la producción de l-lisina mediante el uso de la misma. |
| CN113308426B (zh) * | 2021-05-27 | 2022-10-18 | 齐鲁工业大学 | 一种改造tk基因5′端序列的重组棒状杆菌及其应用 |
| KR102703209B1 (ko) * | 2021-10-14 | 2024-09-05 | 대상 주식회사 | L-라이신 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-라이신의 생산 방법 |
| CN113957073B (zh) * | 2021-10-19 | 2023-09-01 | 山东寿光巨能金玉米开发有限公司 | 一种tkt基因启动子突变体及其在生产L-赖氨酸中的应用 |
| CN119301244A (zh) | 2022-05-18 | 2025-01-10 | 赢创运营有限公司 | 去铁胺及其类似物的生物技术生产 |
| WO2023222505A1 (en) | 2022-05-18 | 2023-11-23 | Evonik Operations Gmbh | Biotechnological production of monomers of bisucaberins, desferrioxamines and analogs thereof |
| WO2023222515A1 (en) | 2022-05-18 | 2023-11-23 | Evonik Operations Gmbh | Biotechnological production of bisucaberins, desferrioxamines and analogs thereof |
| KR102838147B1 (ko) | 2023-03-17 | 2025-07-28 | 씨제이제일제당 주식회사 | 5'-utr 변이 서열 및 이의 용도 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5358866A (en) * | 1991-07-03 | 1994-10-25 | The United States Of America As Represented By The Department Of Health And Human Services | Cytosine deaminase negative selection system for gene transfer techniques and therapies |
| EP0796912B9 (de) * | 1994-12-09 | 2013-08-28 | Ajinomoto Co., Inc. | Neues lysin decarboxylase gen und verfahren zur herstellung von l-lysin |
| RU2197528C2 (ru) * | 1995-06-07 | 2003-01-27 | Адзиномото Ко., Инк. | Способ получения l-лизина (варианты) и рекомбинантная днк, используемая для его осуществления (варианты) |
| KR0159812B1 (ko) | 1995-12-20 | 1998-11-16 | 손경식 | 코리네박테리움 글루타미컴 씨에이치 77 및 이 균주를 이용한 l-라이신의 제조 방법 |
| JP4075087B2 (ja) | 1996-12-05 | 2008-04-16 | 味の素株式会社 | Ｌ−リジンの製造法 |
| DE19831609B4 (de) * | 1997-10-04 | 2009-11-12 | Evonik Degussa Gmbh | Verfahren zur Herstellung von Aminosäuren der Aspartat- und/oder Glutamatfamilie und im Verfahren einsetzbare Mittel |
| ID26644A (id) * | 1997-10-04 | 2001-01-25 | Forschungszentrum Juelich Gmbh | Metoda untuk produksi mikroba dari asam amino aspartat dan / atau keluarga glutamat dan zat-zat yang dapat digunakan dalam metoda tersebut |
| DE19931317A1 (de) * | 1999-07-07 | 2001-01-11 | Degussa | L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von L-Lysin |
| US6171833B1 (en) * | 1998-12-23 | 2001-01-09 | Massachusetts Institute Of Technology | Pyruvate carboxylase from corynebacterium glutamicum |
| EP1147198A1 (de) * | 1998-12-23 | 2001-10-24 | Massachusetts Institute Of Technology | Pyruvat-carboxylase aus corynebacterium glutamicum |
| US20020086371A1 (en) | 1999-07-07 | 2002-07-04 | Degussa-Huls Aktiengesellschaft | L-lysine-producing corynebacteria and process for the preparation of L-lysine |
| US6797509B1 (en) * | 1999-07-09 | 2004-09-28 | Degussa-Huls Ag | Nucleotide sequences which code for the tal gene |
| PL358913A1 (en) * | 2000-03-17 | 2004-08-23 | Degussa Aktiengesellschaft | Process for the fermentative preparation of l-amino acids with amplification of the tkt gene |
| KR100397322B1 (ko) | 2000-12-30 | 2003-09-06 | 씨제이 주식회사 | 엘-라이신의 제조방법 |
| EP1491625B1 (de) * | 2002-03-19 | 2010-07-21 | Kyowa Hakko Bio Co., Ltd. | Mutierte isopropylmalatisomerase |
| DE10361268A1 (de) * | 2003-12-24 | 2005-07-28 | Degussa Ag | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| DE102004011248A1 (de) * | 2004-03-09 | 2005-09-22 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
| EP2080769A3 (de) | 2004-07-02 | 2010-12-01 | Metanomics GmbH | Verfahren zur Herstellung von Feinchemikalien |
| EP2386650B1 (de) * | 2006-04-07 | 2013-07-03 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Lysin unter Verwendung des gap Promotors |
| BRPI0716980A2 (pt) | 2006-09-15 | 2013-10-22 | Cj Cheiljedang Corp | Corynebacteria com produtividade de l-lisina aumentada e método de produção da l-lisina usando a mesma |
| HUE028873T2 (en) * | 2006-10-24 | 2017-01-30 | Basf Se | A method for increasing gene expression using modified codon usage |
| US8133714B2 (en) * | 2007-09-27 | 2012-03-13 | Evonik Degussa Gmbh | Process for the fermentative preparation of organic chemical compounds using coryneform bacteria in which the SugR gene is present in attenuated form |
| KR100930203B1 (ko) | 2008-01-28 | 2009-12-07 | 씨제이제일제당 (주) | 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법 |
| KR100987281B1 (ko) | 2008-01-31 | 2010-10-12 | 씨제이제일제당 (주) | 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법 |
| CN102124119A (zh) * | 2008-04-30 | 2011-07-13 | 巴斯夫欧洲公司 | 使用具有降低的异柠檬酸脱氢酶活性的微生物生产精细化学药品的方法 |
| GB0809169D0 (en) * | 2008-05-20 | 2008-06-25 | Sinvent As | Method of L-lysine production |
| DE102008001874A1 (de) * | 2008-05-20 | 2009-11-26 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren |
| RU2535973C2 (ru) | 2010-06-15 | 2014-12-20 | Пайк Кванг Индастриал Ко., Лтд. | Способ продуцирования аминокислот семейства аспартата с использованием микроорганизмов |
| DE102011118019A1 (de) | 2011-06-28 | 2013-01-03 | Evonik Degussa Gmbh | Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens |
| CN109251934B (zh) * | 2011-12-21 | 2023-07-18 | Cj第一制糖株式会社 | 利用具有产生l-赖氨酸能力的微生物产生l-赖氨酸的方法 |
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