MX353594B - Procedimiento para producir l-lisina usando microorganismos que tienen capacidad para producir l-lisina. - Google Patents

Procedimiento para producir l-lisina usando microorganismos que tienen capacidad para producir l-lisina.

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Publication number
MX353594B
MX353594B MX2014007385A MX2014007385A MX353594B MX 353594 B MX353594 B MX 353594B MX 2014007385 A MX2014007385 A MX 2014007385A MX 2014007385 A MX2014007385 A MX 2014007385A MX 353594 B MX353594 B MX 353594B
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MX
Mexico
Prior art keywords
lysine
microorganisms
producing
hereinafter
ability
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MX2014007385A
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English (en)
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MX2014007385A (es
Inventor
Sang Hee Park
Jun Ok Moon
Sang Jo Lim
Kwang Ho Lee
Jae Woo Jang
Su Jin Park
Original Assignee
Cj Cheiljedang Corp
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Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of MX2014007385A publication Critical patent/MX2014007385A/es
Publication of MX353594B publication Critical patent/MX353594B/es

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    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
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    • C12Y—ENZYMES
    • C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01—Transketolases and transaldolases (2.2.1)
    • C12Y202/01001—Transketolase (2.2.1.1)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02004—Aspartate kinase (2.7.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01001—Pyruvate carboxylase (6.4.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/101—Plasmid DNA for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Abstract

La presente invención se refiere a un polinucleótido modificado que codifica aspartato quinasa; EC: 2.7.2.4 en lo sucesivo en el presente documento denominado LysC), transcetolasa; (EC: 2.2.1.1 en lo sucesivo en el presente documento denominado Tkt) o piruvato carboxilasa (EE: 6.4.1.1 en lo sucesivo en lo sucesivo en el presente documento denominado Pyc), en el que el cordón de inicio está sustituido con ATG, un vector que incluye el mismo, un microorganismo transformado con el vector, y un procedimiento para producir L-lisina utilizando el mismo.
MX2014007385A 2011-12-21 2012-12-21 Procedimiento para producir l-lisina usando microorganismos que tienen capacidad para producir l-lisina. MX353594B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20110139527 2011-12-21
PCT/KR2012/011328 WO2013095071A2 (ko) 2011-12-21 2012-12-21 Ｌ-라이신 생산능을 갖는 미생물을 이용하여 ｌ-라이신을 생산하는 방법

Publications (2)

Publication Number Publication Date
MX2014007385A MX2014007385A (es) 2015-08-20
MX353594B true MX353594B (es) 2018-01-18

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MX2014007385A MX353594B (es) 2011-12-21 2012-12-21 Procedimiento para producir l-lisina usando microorganismos que tienen capacidad para producir l-lisina.

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US (2) US9593354B2 (es)
EP (2) EP2796555B1 (es)
JP (2) JP6082025B2 (es)
KR (3) KR101483344B1 (es)
CN (4) CN104334728B (es)
BR (2) BR112014015215B1 (es)
CA (1) CA2860252C (es)
DK (1) DK2796555T3 (es)
ES (1) ES2696173T3 (es)
IN (1) IN2014MN01298A (es)
MX (1) MX353594B (es)
MY (1) MY171302A (es)
PL (1) PL2796555T3 (es)
RU (3) RU2615454C1 (es)
WO (1) WO2013095071A2 (es)

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Publication number Publication date
EP3404101A2 (en) 2018-11-21
RU2615454C1 (ru) 2017-04-04
KR101483344B1 (ko) 2015-01-15
KR20140093649A (ko) 2014-07-28
CN104334728A (zh) 2015-02-04
CN109251934A (zh) 2019-01-22
RU2014127151A (ru) 2016-02-10
JP6219481B2 (ja) 2017-10-25
JP2017038617A (ja) 2017-02-23
WO2013095071A3 (ko) 2013-08-22
KR20130072183A (ko) 2013-07-01
JP2015500660A (ja) 2015-01-08
ES2696173T3 (es) 2019-01-14
MY171302A (en) 2019-10-08
EP3404101A3 (en) 2018-12-26
JP6082025B2 (ja) 2017-02-15
CN105483145A (zh) 2016-04-13
KR101483395B1 (ko) 2015-01-16
KR20140090130A (ko) 2014-07-16
RU2588665C2 (ru) 2016-07-10
CN105624175A (zh) 2016-06-01
CA2860252A1 (en) 2013-06-27
MX2014007385A (es) 2015-08-20
CA2860252C (en) 2019-07-23
WO2013095071A2 (ko) 2013-06-27
CN104334728B (zh) 2018-09-25
BR122021015693B1 (pt) 2022-05-03
BR112014015215A2 (pt) 2018-11-06
EP2796555A4 (en) 2015-12-09
EP2796555A2 (en) 2014-10-29
KR101483396B1 (ko) 2015-01-16
RU2616870C1 (ru) 2017-04-18
CN109251934B (zh) 2023-07-18
US9938546B2 (en) 2018-04-10
IN2014MN01298A (es) 2015-07-03
DK2796555T3 (en) 2018-12-10
PL2796555T3 (pl) 2019-04-30
US20170145453A1 (en) 2017-05-25
US9593354B2 (en) 2017-03-14
EP2796555B1 (en) 2018-08-29
US20150099281A1 (en) 2015-04-09
BR112014015215B1 (pt) 2021-11-23
CN105483145B (zh) 2021-04-06

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