IN2014CN04039A - - Google Patents
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- Publication number
- IN2014CN04039A IN2014CN04039A IN4039CHN2014A IN2014CN04039A IN 2014CN04039 A IN2014CN04039 A IN 2014CN04039A IN 4039CHN2014 A IN4039CHN2014 A IN 4039CHN2014A IN 2014CN04039 A IN2014CN04039 A IN 2014CN04039A
- Authority
- IN
- India
- Prior art keywords
- secretory production
- heterologous protein
- protein
- activity
- produce
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 230000003248 secreting effect Effects 0.000 abstract 4
- 241000186254 coryneform bacterium Species 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 101710116957 D-alanyl-D-alanine carboxypeptidase Proteins 0.000 abstract 1
- 101710099182 S-layer protein Proteins 0.000 abstract 1
- 101710183296 Surface layer protein Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2011144497/10A RU2011144497A (ru) | 2011-11-02 | 2011-11-02 | Способ секреторного получения белка |
| JP2011240745 | 2011-11-02 | ||
| PCT/JP2012/078906 WO2013065869A1 (en) | 2011-11-02 | 2012-11-01 | Method for secretory production of protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN04039A true IN2014CN04039A (enrdf_load_stackoverflow) | 2015-10-23 |
Family
ID=47222244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4039CHN2014 IN2014CN04039A (enrdf_load_stackoverflow) | 2011-11-02 | 2012-11-01 |
Country Status (8)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012333451B2 (en) | 2011-11-02 | 2015-05-21 | Ajinomoto Co., Inc. | Method for secretory production of protein |
| IN2014CN04002A (enrdf_load_stackoverflow) | 2011-11-02 | 2015-10-23 | Ajinomoto Kk | |
| RU2013119826A (ru) | 2013-04-29 | 2014-11-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | Коринеформная бактерия и способ получения гетерологичных гибридных белков |
| EP3061828B1 (en) | 2013-10-23 | 2024-08-28 | Ajinomoto Co., Inc. | Method for producing target substance |
| CA2947529C (en) * | 2014-05-02 | 2022-06-21 | Shinshu University | Antibody gene expression-secretion system |
| CN107124884B (zh) * | 2014-07-25 | 2022-11-01 | 纪念斯隆-凯特林癌症中心 | 双特异性her2和cd3结合分子 |
| JP6741000B2 (ja) | 2015-04-24 | 2020-08-19 | 味の素株式会社 | タンパク質の分泌生産法 |
| CN109937258B (zh) * | 2016-10-21 | 2023-06-23 | 味之素株式会社 | 蛋白质的分泌产生方法 |
| WO2018074578A1 (ja) | 2016-10-21 | 2018-04-26 | 味の素株式会社 | タンパク質の分泌生産法 |
| EP3601583A1 (en) | 2017-03-28 | 2020-02-05 | Ajinomoto Co., Inc. | Method for producing rna |
| BR112020016770A2 (pt) | 2018-02-20 | 2020-12-15 | Ajinomoto Co., Inc. | Método para induzir silenciamento de rna e para produzir uma composição para induzir silenciamento de rna em um organismo-alvo, e, composição para induzir silenciamento de rna em um organismo-alvo |
| EP3783106A4 (en) | 2018-04-20 | 2022-01-05 | Ajinomoto Co., Inc. | PROCESS FOR THE SECRETION OF A PROTEIN |
| WO2020071538A1 (en) | 2018-10-05 | 2020-04-09 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
| AU2019364829B2 (en) | 2018-10-25 | 2025-11-20 | Ajinomoto Co., Inc. | Method for secretory production of protein |
| CN111909879B (zh) * | 2020-08-24 | 2023-04-28 | 江南大学 | 一种高效表达外源蛋白的谷氨酸棒杆菌诱变菌株及应用 |
| US12180521B2 (en) | 2021-02-19 | 2024-12-31 | Theripion, Inc. | Paraoxonase fusion polypeptides and related compositions and methods |
| WO2023282315A1 (ja) | 2021-07-07 | 2023-01-12 | 味の素株式会社 | 非天然アミノ酸含有タンパク質の分泌生産法 |
| CN119053709A (zh) | 2022-04-15 | 2024-11-29 | 味之素株式会社 | 培养肉的制造方法 |
| KR20250151452A (ko) | 2023-02-16 | 2025-10-21 | 아지노모토 가부시키가이샤 | 단백질의 분비 생산법 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57134500A (en) | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
| JPS57183799A (en) | 1981-04-17 | 1982-11-12 | Kyowa Hakko Kogyo Co Ltd | Novel plasmid |
| JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドｐｃｇ２ |
| JPS58192900A (ja) | 1982-05-04 | 1983-11-10 | Ajinomoto Co Inc | 複合プラスミド |
| US4965197A (en) | 1987-06-12 | 1990-10-23 | Massachusetts Institute Of Technology | Coryneform expression and secretion system |
| JPH01191686A (ja) | 1988-01-26 | 1989-08-01 | Mitsubishi Petrochem Co Ltd | 複合プラスミド |
| US5185262A (en) | 1988-07-27 | 1993-02-09 | Mitsubishi Petrochemical Co., Ltd. | DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism |
| JP2678995B2 (ja) | 1988-09-08 | 1997-11-19 | 三菱化学株式会社 | トリプトフアンシンターゼの製造法 |
| JP2973446B2 (ja) | 1990-01-11 | 1999-11-08 | 三菱化学株式会社 | 新規プラスミドベクター |
| JPH07108228B2 (ja) | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
| JP2925776B2 (ja) | 1991-04-22 | 1999-07-28 | 三洋電機株式会社 | 吸収式冷凍機 |
| JPH06502548A (ja) | 1991-07-30 | 1994-03-24 | オルサン | 特にコリネバクテリア中で用いることのできる蛋白質の発現および分泌系 |
| NZ291414A (en) | 1994-08-26 | 1998-05-27 | Novo Nordisk As | Microbial transglutaminases and methods of production using fungi and dna constructs |
| DE69629719T2 (de) | 1995-01-19 | 2004-07-08 | Novozymes A/S | Transglutaminasen aus oomyzeten |
| JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
| JP4035855B2 (ja) | 1996-06-05 | 2008-01-23 | 味の素株式会社 | Ｌ−リジンの製造法 |
| JP3711658B2 (ja) | 1996-10-07 | 2005-11-02 | 味の素株式会社 | コリネバクテリウム・アンモニアゲネス由来の新規な細胞表層蛋白質 |
| JP4168463B2 (ja) | 1996-12-05 | 2008-10-22 | 味の素株式会社 | Ｌ−リジンの製造法 |
| JPH11169182A (ja) | 1997-12-10 | 1999-06-29 | Mitsubishi Chemical Corp | コリネ型細菌内で蛋白質を効率よく培地中へ分泌させる変異型分泌装置遺伝子 |
| US7033802B1 (en) * | 1998-03-06 | 2006-04-25 | Ajinomoto Co., Inc. | Penicillin binding protein gene and process for producing L-glutamic acid |
| JP2000262288A (ja) | 1999-03-16 | 2000-09-26 | Ajinomoto Co Inc | コリネ型細菌の温度感受性プラスミド |
| US20050244935A1 (en) | 1999-06-25 | 2005-11-03 | Basf Ag | Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport |
| DE60042552D1 (de) | 1999-08-02 | 2009-08-27 | Archer Daniels Midland Co | Metabolische manipulation der produktion von aminosäuren |
| EP1219713B1 (en) | 1999-09-30 | 2011-11-09 | Ajinomoto Co., Inc. | Process for producing transglutaminase |
| HU229834B1 (en) | 2000-01-21 | 2014-09-29 | Ajinomoto Kk | Process for producing l-lysine |
| ATE447615T1 (de) | 2001-03-30 | 2009-11-15 | Ajinomoto Kk | Verfahren zur sekretion und produktion von protein |
| AU2003268693A1 (en) * | 2002-09-30 | 2004-04-19 | Ajinomoto Co., Inc. | Method of producing stable isotope-labeled protein |
| DK1602722T3 (da) | 2003-03-07 | 2011-05-16 | Ajinomoto Kk | Fremgangsmåde til fremstilling af mikrobiel transglutaminase |
| JP4705026B2 (ja) | 2004-03-19 | 2011-06-22 | ジェノミディア株式会社 | 血管内皮増殖促進遺伝子 |
| KR101089559B1 (ko) | 2004-03-31 | 2011-12-06 | 아지노모토 가부시키가이샤 | 바실러스 또는 에스케리키아 속에 속하는 세균을 사용하여 발효에 의해 퓨린 뉴클레오사이드 및 뉴클레오타이드를 제조하는 방법 |
| DK1748077T3 (da) * | 2004-04-20 | 2013-04-08 | Ajinomoto Kk | Fremgangsmåde til fremstilling af protein |
| CN1989238B (zh) | 2004-05-20 | 2010-05-26 | 味之素株式会社 | 生产琥珀酸的细菌和生产琥珀酸的方法 |
| JP4595506B2 (ja) | 2004-11-25 | 2010-12-08 | 味の素株式会社 | Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法 |
| WO2006092449A2 (en) | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| US7723097B2 (en) | 2005-03-11 | 2010-05-25 | Archer-Daniels-Midland Company | Escherichia coli strains that over-produce L-threonine and processes for their production |
| RU2365622C2 (ru) | 2006-12-22 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПРОДУКЦИИ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Escherichia ИЛИ Bacillus |
| JP5445453B2 (ja) | 2008-07-09 | 2014-03-19 | 味の素株式会社 | アミノヒドロキシ安息香酸類の製造方法 |
| IN2014CN04002A (enrdf_load_stackoverflow) | 2011-11-02 | 2015-10-23 | Ajinomoto Kk | |
| AU2012333451B2 (en) | 2011-11-02 | 2015-05-21 | Ajinomoto Co., Inc. | Method for secretory production of protein |
-
2012
- 2012-11-01 AU AU2012333451A patent/AU2012333451B2/en active Active
- 2012-11-01 JP JP2014539576A patent/JP6020581B2/ja active Active
- 2012-11-01 KR KR1020147015040A patent/KR101653555B1/ko active Active
- 2012-11-01 CN CN201280054079.5A patent/CN103946371B/zh active Active
- 2012-11-01 EP EP12790980.2A patent/EP2748340B1/en active Active
- 2012-11-01 IN IN4039CHN2014 patent/IN2014CN04039A/en unknown
- 2012-11-01 WO PCT/JP2012/078906 patent/WO2013065869A1/en not_active Ceased
-
2014
- 2014-04-29 US US14/264,353 patent/US9187554B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012333451A1 (en) | 2014-04-03 |
| WO2013065869A1 (en) | 2013-05-10 |
| RU2014122201A (ru) | 2015-12-10 |
| CN103946371A (zh) | 2014-07-23 |
| CN103946371B (zh) | 2016-07-06 |
| JP6020581B2 (ja) | 2016-11-02 |
| EP2748340A1 (en) | 2014-07-02 |
| KR20140088215A (ko) | 2014-07-09 |
| EP2748340B1 (en) | 2016-06-01 |
| US20140255996A1 (en) | 2014-09-11 |
| AU2012333451B2 (en) | 2015-05-21 |
| KR101653555B1 (ko) | 2016-09-02 |
| JP2014532424A (ja) | 2014-12-08 |
| US9187554B2 (en) | 2015-11-17 |
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