IN2014CN04039A - - Google Patents
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- Publication number
- IN2014CN04039A IN2014CN04039A IN4039CHN2014A IN2014CN04039A IN 2014CN04039 A IN2014CN04039 A IN 2014CN04039A IN 4039CHN2014 A IN4039CHN2014 A IN 4039CHN2014A IN 2014CN04039 A IN2014CN04039 A IN 2014CN04039A
- Authority
- IN
- India
- Prior art keywords
- secretory production
- heterologous protein
- protein
- activity
- produce
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 230000003248 secreting effect Effects 0.000 abstract 4
- 241000186254 coryneform bacterium Species 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 101710116957 D-alanyl-D-alanine carboxypeptidase Proteins 0.000 abstract 1
- 101710099182 S-layer protein Proteins 0.000 abstract 1
- 101710183296 Surface layer protein Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2011144497/10A RU2011144497A (ru) | 2011-11-02 | 2011-11-02 | Способ секреторного получения белка |
| JP2011240745 | 2011-11-02 | ||
| PCT/JP2012/078906 WO2013065869A1 (en) | 2011-11-02 | 2012-11-01 | Method for secretory production of protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN04039A true IN2014CN04039A (enrdf_load_stackoverflow) | 2015-10-23 |
Family
ID=47222244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4039CHN2014 IN2014CN04039A (enrdf_load_stackoverflow) | 2011-11-02 | 2012-11-01 |
Country Status (8)
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2014CN04039A (enrdf_load_stackoverflow) | 2011-11-02 | 2015-10-23 | Ajinomoto Kk | |
| JP6136930B2 (ja) | 2011-11-02 | 2017-05-31 | 味の素株式会社 | タンパク質の分泌生産法 |
| RU2013119826A (ru) | 2013-04-29 | 2014-11-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | Коринеформная бактерия и способ получения гетерологичных гибридных белков |
| BR112016008830B1 (pt) | 2013-10-23 | 2023-02-23 | Ajinomoto Co., Inc | Método para produzir uma substância alvo |
| WO2015166641A1 (ja) * | 2014-05-02 | 2015-11-05 | 国立大学法人信州大学 | 抗体遺伝子の発現・分泌システム |
| ES2832704T3 (es) * | 2014-07-25 | 2021-06-11 | Memorial Sloan Kettering Cancer Center | Moléculas de unión a HER2 y CD3 biespecíficas |
| WO2016171224A1 (ja) | 2015-04-24 | 2016-10-27 | 味の素株式会社 | タンパク質の分泌生産法 |
| JP7159867B2 (ja) * | 2016-10-21 | 2022-10-25 | 味の素株式会社 | タンパク質の分泌生産法 |
| JP7021639B2 (ja) | 2016-10-21 | 2022-02-17 | 味の素株式会社 | タンパク質の分泌生産法 |
| EP3601583A1 (en) | 2017-03-28 | 2020-02-05 | Ajinomoto Co., Inc. | Method for producing rna |
| BR112020016770A2 (pt) | 2018-02-20 | 2020-12-15 | Ajinomoto Co., Inc. | Método para induzir silenciamento de rna e para produzir uma composição para induzir silenciamento de rna em um organismo-alvo, e, composição para induzir silenciamento de rna em um organismo-alvo |
| AU2019256065B2 (en) | 2018-04-20 | 2024-11-28 | Ajinomoto Co., Inc. | Method for secretory production of protein |
| WO2020071538A1 (en) | 2018-10-05 | 2020-04-09 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
| EP3872096A4 (en) | 2018-10-25 | 2022-11-30 | Ajinomoto Co., Inc. | PROCESS FOR THE SECRETORY PRODUCTION OF A PROTEIN |
| CN111909879B (zh) * | 2020-08-24 | 2023-04-28 | 江南大学 | 一种高效表达外源蛋白的谷氨酸棒杆菌诱变菌株及应用 |
| WO2022178078A1 (en) | 2021-02-19 | 2022-08-25 | Theripion, Inc. | Paraoxonase fusion polypeptides and related compositions and methods |
| KR20240032941A (ko) | 2021-07-07 | 2024-03-12 | 아지노모토 가부시키가이샤 | 비천연 아미노산 함유 단백질의 분비 생산법 |
| CN119053709A (zh) | 2022-04-15 | 2024-11-29 | 味之素株式会社 | 培养肉的制造方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57134500A (en) | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
| JPS57183799A (en) | 1981-04-17 | 1982-11-12 | Kyowa Hakko Kogyo Co Ltd | Novel plasmid |
| JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドｐｃｇ２ |
| JPS58192900A (ja) | 1982-05-04 | 1983-11-10 | Ajinomoto Co Inc | 複合プラスミド |
| US4965197A (en) | 1987-06-12 | 1990-10-23 | Massachusetts Institute Of Technology | Coryneform expression and secretion system |
| JPH01191686A (ja) | 1988-01-26 | 1989-08-01 | Mitsubishi Petrochem Co Ltd | 複合プラスミド |
| JP2678995B2 (ja) | 1988-09-08 | 1997-11-19 | 三菱化学株式会社 | トリプトフアンシンターゼの製造法 |
| US5185262A (en) | 1988-07-27 | 1993-02-09 | Mitsubishi Petrochemical Co., Ltd. | DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism |
| JP2973446B2 (ja) | 1990-01-11 | 1999-11-08 | 三菱化学株式会社 | 新規プラスミドベクター |
| JPH07108228B2 (ja) | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
| JP2925776B2 (ja) | 1991-04-22 | 1999-07-28 | 三洋電機株式会社 | 吸収式冷凍機 |
| WO1993003158A1 (fr) | 1991-07-30 | 1993-02-18 | Orsan | Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries |
| NZ291414A (en) | 1994-08-26 | 1998-05-27 | Novo Nordisk As | Microbial transglutaminases and methods of production using fungi and dna constructs |
| BR9606772A (pt) | 1995-01-19 | 1998-01-06 | Novo Nordisk As | Preparação de transglutaminase processos para produção da mesma e de uma enzima que exibe atividade transglutaminase e para reticulação de proteínas transglutaminase originária construção de dna vetor de expressão recombinante célula enzima composição de transglutaminase e uso da preparação de transglutaminase |
| JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
| JP4035855B2 (ja) | 1996-06-05 | 2008-01-23 | 味の素株式会社 | Ｌ−リジンの製造法 |
| JP3711658B2 (ja) | 1996-10-07 | 2005-11-02 | 味の素株式会社 | コリネバクテリウム・アンモニアゲネス由来の新規な細胞表層蛋白質 |
| JP4168463B2 (ja) | 1996-12-05 | 2008-10-22 | 味の素株式会社 | Ｌ−リジンの製造法 |
| JPH11169182A (ja) | 1997-12-10 | 1999-06-29 | Mitsubishi Chemical Corp | コリネ型細菌内で蛋白質を効率よく培地中へ分泌させる変異型分泌装置遺伝子 |
| CN1299418A (zh) * | 1998-03-06 | 2001-06-13 | 味之素株式会社 | 编码青霉素结合蛋白的基因和生产l－谷氨酸的方法 |
| JP2000262288A (ja) | 1999-03-16 | 2000-09-26 | Ajinomoto Co Inc | コリネ型細菌の温度感受性プラスミド |
| US20050244935A1 (en) | 1999-06-25 | 2005-11-03 | Basf Ag | Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport |
| CN1367823A (zh) | 1999-08-02 | 2002-09-04 | 阿彻·丹尼尔斯－米德兰公司 | 氨基酸生产的代谢工程 |
| BR0014059B1 (pt) | 1999-09-30 | 2013-02-05 | processo para produzir transglutaminase. | |
| US7723081B1 (en) | 2000-01-21 | 2010-05-25 | Ajinomoto Co., Inc. | Bacteria containing aspartate-semialdehyde dehydrogenase, phosphoenolpyruvate carboxylase, and transhydrogenase to produce L-lysine in escherichia, and methods of using same |
| CA2442679C (en) | 2001-03-30 | 2010-06-01 | Ajinomoto Co., Inc. | Methods for secretory production of proteins |
| EP1548116A4 (en) * | 2002-09-30 | 2006-04-05 | Ajinomoto Kk | PROCESS FOR PRODUCING A PROTEIN MARKED BY A STABLE ISOTOPE |
| JP4482938B2 (ja) | 2003-03-07 | 2010-06-16 | 味の素株式会社 | 微生物トランスグルタミナーゼの製造法 |
| US7807176B2 (en) | 2004-03-19 | 2010-10-05 | Genomidea, Inc. | Polypeptide promoting vascular endothelial cell growth |
| JP4760711B2 (ja) | 2004-03-31 | 2011-08-31 | 味の素株式会社 | バチルス属又はエシェリヒア属に属する細菌を使用した発酵によるプリンヌクレオシド及びヌクレオチドの製造方法 |
| DK1748077T3 (da) | 2004-04-20 | 2013-04-08 | Ajinomoto Kk | Fremgangsmåde til fremstilling af protein |
| WO2005113744A1 (ja) | 2004-05-20 | 2005-12-01 | Ajinomoto Co., Inc. | コハク酸生産菌及びコハク酸の製造方法 |
| JP4595506B2 (ja) | 2004-11-25 | 2010-12-08 | 味の素株式会社 | Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法 |
| AU2006219823A1 (en) | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| US7723097B2 (en) | 2005-03-11 | 2010-05-25 | Archer-Daniels-Midland Company | Escherichia coli strains that over-produce L-threonine and processes for their production |
| RU2365622C2 (ru) | 2006-12-22 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПРОДУКЦИИ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Escherichia ИЛИ Bacillus |
| WO2010005099A1 (ja) | 2008-07-09 | 2010-01-14 | 味の素株式会社 | アミノヒドロキシ安息香酸類の製造方法 |
| JP6136930B2 (ja) | 2011-11-02 | 2017-05-31 | 味の素株式会社 | タンパク質の分泌生産法 |
| IN2014CN04039A (enrdf_load_stackoverflow) | 2011-11-02 | 2015-10-23 | Ajinomoto Kk |
-
2012
- 2012-11-01 IN IN4039CHN2014 patent/IN2014CN04039A/en unknown
- 2012-11-01 AU AU2012333451A patent/AU2012333451B2/en active Active
- 2012-11-01 WO PCT/JP2012/078906 patent/WO2013065869A1/en active Application Filing
- 2012-11-01 EP EP12790980.2A patent/EP2748340B1/en active Active
- 2012-11-01 CN CN201280054079.5A patent/CN103946371B/zh active Active
- 2012-11-01 JP JP2014539576A patent/JP6020581B2/ja active Active
- 2012-11-01 KR KR1020147015040A patent/KR101653555B1/ko active Active
-
2014
- 2014-04-29 US US14/264,353 patent/US9187554B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20140255996A1 (en) | 2014-09-11 |
| KR20140088215A (ko) | 2014-07-09 |
| RU2014122201A (ru) | 2015-12-10 |
| AU2012333451A1 (en) | 2014-04-03 |
| EP2748340A1 (en) | 2014-07-02 |
| JP6020581B2 (ja) | 2016-11-02 |
| US9187554B2 (en) | 2015-11-17 |
| WO2013065869A1 (en) | 2013-05-10 |
| JP2014532424A (ja) | 2014-12-08 |
| AU2012333451B2 (en) | 2015-05-21 |
| EP2748340B1 (en) | 2016-06-01 |
| KR101653555B1 (ko) | 2016-09-02 |
| CN103946371A (zh) | 2014-07-23 |
| CN103946371B (zh) | 2016-07-06 |
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