DK1748077T3 - Fremgangsmåde til fremstilling af protein - Google Patents

Fremgangsmåde til fremstilling af protein

Info

Publication number
DK1748077T3
DK1748077T3 DK05734619.9T DK05734619T DK1748077T3 DK 1748077 T3 DK1748077 T3 DK 1748077T3 DK 05734619 T DK05734619 T DK 05734619T DK 1748077 T3 DK1748077 T3 DK 1748077T3
Authority
DK
Denmark
Prior art keywords
procedure
producing protein
protein
producing
Prior art date
Application number
DK05734619.9T
Other languages
English (en)
Inventor
Masayo Date
Yoshimi Kikuchi
Hiroshi Itaya
Nami Nakamura
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of DK1748077T3 publication Critical patent/DK1748077T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK05734619.9T 2004-04-20 2005-04-20 Fremgangsmåde til fremstilling af protein DK1748077T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004124196 2004-04-20
JP2005005896 2005-01-13
PCT/JP2005/007518 WO2005103278A1 (ja) 2004-04-20 2005-04-20 タンパク質の製造法

Publications (1)

Publication Number Publication Date
DK1748077T3 true DK1748077T3 (da) 2013-04-08

Family

ID=35196990

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05734619.9T DK1748077T3 (da) 2004-04-20 2005-04-20 Fremgangsmåde til fremstilling af protein

Country Status (5)

Country Link
US (1) US8597907B2 (da)
EP (1) EP1748077B1 (da)
JP (1) JP4730302B2 (da)
DK (1) DK1748077T3 (da)
WO (1) WO2005103278A1 (da)

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ES2313878T3 (es) 2000-01-21 2009-03-16 Ajinomoto Co., Inc. Procedimiento para la produccion de l-lisina.
CN100381569C (zh) * 2003-03-07 2008-04-16 味之素株式会社 微生物转谷氨酰胺酶的生产方法
JP4730302B2 (ja) 2004-04-20 2011-07-20 味の素株式会社 タンパク質の製造法
CN101631860B (zh) * 2007-02-15 2012-07-18 味之素株式会社 引入二硫键的转谷氨酰胺酶
DE102008025926A1 (de) * 2008-05-29 2009-12-03 Henkel Ag & Co. Kgaa Sekretionsoptimierter Mikroorganismus
JP5445453B2 (ja) * 2008-07-09 2014-03-19 味の素株式会社 アミノヒドロキシ安息香酸類の製造方法
WO2010101256A1 (ja) 2009-03-06 2010-09-10 味の素株式会社 放線菌由来の耐熱性トランスグルタミナーゼ
JP5853695B2 (ja) * 2010-02-23 2016-02-09 東レ株式会社 カダベリンの製造方法
JP5858251B2 (ja) 2011-06-23 2016-02-10 味の素株式会社 免疫グロブリン折りたたみ構造を持つタンパク質と、サブユニット構造となりうるタンパク質とを融合させた単量体タンパク質からなる多量体タンパク質の調製方法
EP2772546B1 (en) 2011-10-25 2019-05-15 Ajinomoto Co., Inc. Secretion production method for protein
WO2013065869A1 (en) 2011-11-02 2013-05-10 Ajinomoto Co.,Inc. Method for secretory production of protein
AU2012333515B2 (en) 2011-11-02 2015-07-16 Ajinomoto Co., Inc. Method for secreting and producing proteins
JPWO2013118544A1 (ja) * 2012-02-08 2015-05-11 味の素株式会社 タンパク質の分泌生産法
US20140023618A1 (en) * 2012-07-23 2014-01-23 Applied Biology Systems and methods for treatment of androgenetic skin conditions by microbial organisms
CN104487586B (zh) 2013-02-18 2017-03-08 味之素株式会社 基于沉淀的蛋白质制造方法
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
MX368142B (es) 2013-04-30 2019-09-20 Intas Pharmaceuticals Ltd Metodo de clonacion, expresion y purificacion novedoso para la preparacion de ranibizumab.
EP3072971B1 (en) * 2015-03-25 2019-08-28 SenseUp GmbH Sensors for detection and quantification of microbiological protein secretion
EP3287523B1 (en) * 2015-04-24 2022-06-29 Ajinomoto Co., Inc. Method for secretory production of protein
JP6729600B2 (ja) 2015-11-12 2020-07-22 味の素株式会社 Ｎε−アシル−Ｌ−リジンの製造方法
EP3453758A4 (en) 2016-05-02 2019-12-04 Ajinomoto Co., Inc. FC PROTEIN WITH AZID GROUP
EP3530747A4 (en) 2016-10-21 2020-07-22 Ajinomoto Co., Inc. SECRETORY PROTEIN PRODUCTION PROCESS
AU2017347016B2 (en) * 2016-10-21 2021-09-23 Ajinomoto Co., Inc. Secretory production method for protein
WO2018135027A1 (ja) 2017-01-19 2018-07-26 味の素株式会社 ヘキスロン酸残基が異性化されたヘパロサン化合物の製造方法
EP3601583A1 (en) 2017-03-28 2020-02-05 Ajinomoto Co., Inc. Method for producing rna
EP3415622A1 (en) 2017-06-14 2018-12-19 Evonik Degussa GmbH Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases
CN111065740A (zh) 2017-09-05 2020-04-24 味之素株式会社 2-o-硫酸化酶突变体和3-o-硫酸化酶突变体及其使用方法
AU2018334768A1 (en) 2017-09-25 2020-04-16 Ajinomoto Co., Inc. Protein production method and disaccharide production method
KR102620914B1 (ko) 2017-10-10 2024-01-05 아지노모토 가부시키가이샤 단백질의 제조 방법
WO2019078095A1 (en) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY
CN111757673A (zh) 2018-02-20 2020-10-09 味之素株式会社 诱导rna沉默的方法
KR20210002575A (ko) 2018-04-20 2021-01-08 아지노모토 가부시키가이샤 단백질의 분비 생산법
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
EP3872096A4 (en) 2018-10-25 2022-11-30 Ajinomoto Co., Inc. PROCESS FOR THE SECRETORY PRODUCTION OF A PROTEIN
CN115836127A (zh) 2020-06-11 2023-03-21 味之素株式会社 蛋白的制造方法
CN117642511A (zh) 2021-07-07 2024-03-01 味之素株式会社 含非天然氨基酸的蛋白质的分泌生产方法
WO2023063314A1 (ja) 2021-10-11 2023-04-20 味の素株式会社 異種Ｔａｔ系タンパク質を発現するよう改変された細菌

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965197A (en) * 1987-06-12 1990-10-23 Massachusetts Institute Of Technology Coryneform expression and secretion system
EP0551506A1 (fr) 1991-07-30 1993-07-21 Orsan Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries
JPH06169780A (ja) 1992-12-07 1994-06-21 Mitsubishi Petrochem Co Ltd 膜蛋白質の膜への組み込みに関与する遺伝子ｄｎａ
JPH06277073A (ja) 1993-03-30 1994-10-04 Mitsubishi Petrochem Co Ltd 蛋白質のトランスロケーションマシナリーをコードする遺伝子ｄｎａ
JPH07107981A (ja) 1993-10-08 1995-04-25 Mitsubishi Chem Corp 新規ｄｎａ断片
JPH11169182A (ja) 1997-12-10 1999-06-29 Mitsubishi Chemical Corp コリネ型細菌内で蛋白質を効率よく培地中へ分泌させる変異型分泌装置遺伝子
US6022952A (en) * 1998-04-01 2000-02-08 University Of Alberta Compositions and methods for protein secretion
ATE532870T1 (de) * 1999-09-30 2011-11-15 Ajinomoto Kk Verfahren zur herstellung von transglutaminase
EP1356060B1 (en) 2000-09-18 2005-12-14 Genencor International, Inc. Twin-arginine translocation in bacillus
DK1375664T3 (da) * 2001-03-30 2010-02-08 Ajinomoto Kk Fremgangsmåde til udskillelsen og fremstilling af protein
WO2003083056A2 (en) * 2002-03-23 2003-10-09 Research Development Foundation Secretion of proteins with multiple disulfide bonds in bacteria and uses thereof
AU2002950473A0 (en) * 2002-07-26 2002-09-12 Commonwealth Scientific And Industrial Research Organisation Expression system
CN100381569C (zh) * 2003-03-07 2008-04-16 味之素株式会社 微生物转谷氨酰胺酶的生产方法
JP4730302B2 (ja) 2004-04-20 2011-07-20 味の素株式会社 タンパク質の製造法

Also Published As

Publication number Publication date
EP1748077A1 (en) 2007-01-31
US20070184525A1 (en) 2007-08-09
JPWO2005103278A1 (ja) 2008-03-13
WO2005103278A1 (ja) 2005-11-03
US8597907B2 (en) 2013-12-03
EP1748077A4 (en) 2011-09-28
JP4730302B2 (ja) 2011-07-20
EP1748077B1 (en) 2013-02-27

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