WO2013096898A3 - Bioconversion process for producing nylon-7, nylon-7,7 and polyesters - Google Patents

Bioconversion process for producing nylon-7, nylon-7,7 and polyesters Download PDF

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Publication number
WO2013096898A3
WO2013096898A3 PCT/US2012/071472 US2012071472W WO2013096898A3 WO 2013096898 A3 WO2013096898 A3 WO 2013096898A3 US 2012071472 W US2012071472 W US 2012071472W WO 2013096898 A3 WO2013096898 A3 WO 2013096898A3
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WIPO (PCT)
Prior art keywords
nylon
polyesters
producing
bioconversion process
trifunctional
Prior art date
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PCT/US2012/071472
Other languages
French (fr)
Other versions
WO2013096898A2 (en
Inventor
Paul S. Pearlman
Changlin Chen
Adriana BOTES
Alex van Eck CONRADIE
Benjamin D. HERZOG
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Invista Technologies S.A.R.L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from PCT/US2012/044984 external-priority patent/WO2013003744A2/en
Application filed by Invista Technologies S.A.R.L filed Critical Invista Technologies S.A.R.L
Priority to US14/367,484 priority Critical patent/US10689673B2/en
Priority to BR112014015077-0A priority patent/BR112014015077A2/en
Priority to CN201280070432.9A priority patent/CN104126012A/en
Priority to JP2014548982A priority patent/JP2015500663A/en
Priority to EP12816586.7A priority patent/EP2794897A2/en
Publication of WO2013096898A2 publication Critical patent/WO2013096898A2/en
Publication of WO2013096898A3 publication Critical patent/WO2013096898A3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/26Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from polyamines and polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/001Amines; Imines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/005Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/50Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters.
PCT/US2012/071472 2011-06-30 2012-12-21 Bioconversion process for producing nylon-7, nylon-7,7 and polyesters WO2013096898A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US14/367,484 US10689673B2 (en) 2011-06-30 2012-12-21 Bioconversion process for producing nylon-7, nylon-7,7 and polyesters
BR112014015077-0A BR112014015077A2 (en) 2011-12-21 2012-12-21 method for producing a di- or trifunctional alkane
CN201280070432.9A CN104126012A (en) 2011-12-21 2012-12-21 Bioconversion process for producing nylon-7, nylon-7,7 and polyesters
JP2014548982A JP2015500663A (en) 2011-12-21 2012-12-21 Biotransformation process for producing nylon-7, nylon-7,7, and polyester
EP12816586.7A EP2794897A2 (en) 2011-12-21 2012-12-21 Bioconversion process for producing nylon-7, nylon-7,7 and polyesters

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201161578289P 2011-12-21 2011-12-21
US201161578265P 2011-12-21 2011-12-21
US201161578272P 2011-12-21 2011-12-21
US61/578,289 2011-12-21
US61/578,265 2011-12-21
US61/578,272 2011-12-21
USPCT/US2012/044984 2012-06-29
PCT/US2012/044984 WO2013003744A2 (en) 2011-06-30 2012-06-29 Bioconversion process for producing nylon-7, nylon-7,7 and polyesters

Publications (2)

Publication Number Publication Date
WO2013096898A2 WO2013096898A2 (en) 2013-06-27
WO2013096898A3 true WO2013096898A3 (en) 2014-03-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/071472 WO2013096898A2 (en) 2011-06-30 2012-12-21 Bioconversion process for producing nylon-7, nylon-7,7 and polyesters

Country Status (5)

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EP (1) EP2794897A2 (en)
JP (2) JP2015500663A (en)
CN (1) CN104126012A (en)
BR (1) BR112014015077A2 (en)
WO (1) WO2013096898A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012174451A1 (en) 2011-06-17 2012-12-20 Invista Technologies S.A.R.L. Use of hydrolases to increase monomer content in waste stream
WO2013003744A2 (en) 2011-06-30 2013-01-03 Invista Techonologies S.A R.L Bioconversion process for producing nylon-7, nylon-7,7 and polyesters
US9102958B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
US9102960B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
WO2014093847A2 (en) 2012-12-14 2014-06-19 Invista North America S.A.R.L. METHODS OF PRODUCING 7-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE
WO2014105796A2 (en) * 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via aromatic compounds
US9920336B2 (en) 2012-12-31 2018-03-20 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals from long chain fatty acids via oxidative cleavage
CN105408487A (en) 2012-12-31 2016-03-16 英威达技术有限责任公司 Methods of producing 7-carbon chemicals via methyl-ester shielded carbon chain elongation
CN105026569A (en) * 2012-12-31 2015-11-04 英威达技术有限责任公司 Methods of producing 7-carbon chemicals via pyruvate and succinate semialdehyde aldol condensation
WO2014105788A2 (en) * 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via carbon chain elongation associated with cyclohexane carboxylate synthesis
US9580731B2 (en) 2012-12-31 2017-02-28 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via c1 carbon chain elongation associated with coenzyme B synthesis
WO2014105805A2 (en) 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 6-carbon chemicals via methyl-ester shielded carbon chain elongation
US9745607B2 (en) 2014-05-15 2017-08-29 Invista North America S.A.R.L. Methods of producing 6-carbon chemicals using 2,6-diaminopimelate as precursor to 2-aminopimelate
CN106795530A (en) 2014-06-16 2017-05-31 英威达技术有限责任公司 Method, reagent and cell for biosynthesis compound
WO2015195707A1 (en) 2014-06-16 2015-12-23 Invista Technologies S.A.R.L. Methods, reagents and cells for biosynthesizing compounds
EP3155112A1 (en) 2014-06-16 2017-04-19 Invista Technologies S.à.r.l. Process for producing glutarate and glutaric acid methyl ester
WO2015195678A1 (en) 2014-06-16 2015-12-23 Invista Technologies S.À R.L. Methods, reagents and cells for biosynthesizing compounds
EP3224366A1 (en) * 2014-11-26 2017-10-04 Invista Technologies S.A.R.L. Methods and materials for producing 7-carbon chemicals via a c9 route
CN108998430B (en) * 2018-06-29 2020-11-13 浙江工业大学 Interface self-assembly carbonyl reductase and application thereof in synthesis of (R) -3-hydroxy-3-ethyl phenylpropionate
CN116790698B (en) * 2023-06-21 2024-06-18 南京大学 Method for synthesizing thioaldehyde based on oxidative decarboxylase and application thereof

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JP2015500663A (en) 2015-01-08
EP2794897A2 (en) 2014-10-29
CN104126012A (en) 2014-10-29
BR112014015077A2 (en) 2020-10-27
JP2017131229A (en) 2017-08-03
WO2013096898A2 (en) 2013-06-27

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