IN2014CN04002A - - Google Patents
Info
- Publication number
- IN2014CN04002A IN2014CN04002A IN4002CHN2014A IN2014CN04002A IN 2014CN04002 A IN2014CN04002 A IN 2014CN04002A IN 4002CHN2014 A IN4002CHN2014 A IN 4002CHN2014A IN 2014CN04002 A IN2014CN04002 A IN 2014CN04002A
- Authority
- IN
- India
- Prior art keywords
- polymeric
- coryneform bacteria
- protein secretion
- production capabilities
- proteins
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 241000186031 Corynebacteriaceae Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000028327 secretion Effects 0.000 abstract 2
- 102000005741 Metalloproteases Human genes 0.000 abstract 1
- 108010006035 Metalloproteases Proteins 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011240745 | 2011-11-02 | ||
| PCT/JP2012/078285 WO2013065772A1 (ja) | 2011-11-02 | 2012-11-01 | タンパク質の分泌生産法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN04002A true IN2014CN04002A (enrdf_load_stackoverflow) | 2015-10-23 |
Family
ID=48192110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4002CHN2014 IN2014CN04002A (enrdf_load_stackoverflow) | 2011-11-02 | 2012-11-01 |
Country Status (7)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6136930B2 (ja) | 2011-11-02 | 2017-05-31 | 味の素株式会社 | タンパク質の分泌生産法 |
| IN2014CN04039A (enrdf_load_stackoverflow) | 2011-11-02 | 2015-10-23 | Ajinomoto Kk | |
| BR112016008830B1 (pt) | 2013-10-23 | 2023-02-23 | Ajinomoto Co., Inc | Método para produzir uma substância alvo |
| JP6663221B2 (ja) * | 2014-01-31 | 2020-03-11 | 株式会社カネカ | Ｒ体特異的エノイル−ＣｏＡヒドラターゼ遺伝子の発現が調節された微生物及びそれを用いたポリヒドロキシアルカノエート共重合体の製造方法 |
| WO2016171224A1 (ja) | 2015-04-24 | 2016-10-27 | 味の素株式会社 | タンパク質の分泌生産法 |
| JP7021639B2 (ja) | 2016-10-21 | 2022-02-17 | 味の素株式会社 | タンパク質の分泌生産法 |
| JP7159867B2 (ja) * | 2016-10-21 | 2022-10-25 | 味の素株式会社 | タンパク質の分泌生産法 |
| CN106754533B (zh) * | 2016-12-30 | 2020-06-30 | 四川大学 | 一种具有分解蛋白质性能的棒状杆菌、生产方法及其应用 |
| EP3601583A1 (en) | 2017-03-28 | 2020-02-05 | Ajinomoto Co., Inc. | Method for producing rna |
| WO2019078095A1 (en) | 2017-10-16 | 2019-04-25 | Ajinomoto Co., Inc. | PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY |
| BR112020016770A2 (pt) | 2018-02-20 | 2020-12-15 | Ajinomoto Co., Inc. | Método para induzir silenciamento de rna e para produzir uma composição para induzir silenciamento de rna em um organismo-alvo, e, composição para induzir silenciamento de rna em um organismo-alvo |
| AU2019256065B2 (en) | 2018-04-20 | 2024-11-28 | Ajinomoto Co., Inc. | Method for secretory production of protein |
| WO2020071538A1 (en) | 2018-10-05 | 2020-04-09 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
| EP3872096A4 (en) * | 2018-10-25 | 2022-11-30 | Ajinomoto Co., Inc. | PROCESS FOR THE SECRETORY PRODUCTION OF A PROTEIN |
| KR20240032941A (ko) | 2021-07-07 | 2024-03-12 | 아지노모토 가부시키가이샤 | 비천연 아미노산 함유 단백질의 분비 생산법 |
| CN119053709A (zh) | 2022-04-15 | 2024-11-29 | 味之素株式会社 | 培养肉的制造方法 |
| CN116200416B (zh) * | 2023-02-15 | 2024-03-12 | 北京康乐卫士生物技术股份有限公司 | 一种基于Tac启动子的质粒表达载体构建及其用途 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57134500A (en) | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
| JPS57183799A (en) | 1981-04-17 | 1982-11-12 | Kyowa Hakko Kogyo Co Ltd | Novel plasmid |
| JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドｐｃｇ２ |
| JPS5867679A (ja) | 1981-09-30 | 1983-04-22 | アメリカン・サイアナミド・カンパニ− | イソシアン酸を三量化してシアヌル酸をつくる方法 |
| JPS5877895A (ja) | 1981-11-02 | 1983-05-11 | Ajinomoto Co Inc | プラスミドｐｈｍ１５１９ |
| JPS58192900A (ja) | 1982-05-04 | 1983-11-10 | Ajinomoto Co Inc | 複合プラスミド |
| US4965197A (en) | 1987-06-12 | 1990-10-23 | Massachusetts Institute Of Technology | Coryneform expression and secretion system |
| JPH01191686A (ja) | 1988-01-26 | 1989-08-01 | Mitsubishi Petrochem Co Ltd | 複合プラスミド |
| FR2627508B1 (fr) | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
| JP2678995B2 (ja) | 1988-09-08 | 1997-11-19 | 三菱化学株式会社 | トリプトフアンシンターゼの製造法 |
| US5185262A (en) | 1988-07-27 | 1993-02-09 | Mitsubishi Petrochemical Co., Ltd. | DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism |
| JPH02207791A (ja) | 1989-02-07 | 1990-08-17 | Ajinomoto Co Inc | 微生物の形質転換法 |
| JP2973446B2 (ja) | 1990-01-11 | 1999-11-08 | 三菱化学株式会社 | 新規プラスミドベクター |
| JPH07108228B2 (ja) | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
| WO1993003158A1 (fr) | 1991-07-30 | 1993-02-18 | Orsan | Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries |
| AU4431196A (en) | 1995-01-23 | 1996-08-14 | Novo Nordisk A/S | Dna integration by transposition |
| JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
| JP4035855B2 (ja) | 1996-06-05 | 2008-01-23 | 味の素株式会社 | Ｌ−リジンの製造法 |
| JP3711658B2 (ja) | 1996-10-07 | 2005-11-02 | 味の素株式会社 | コリネバクテリウム・アンモニアゲネス由来の新規な細胞表層蛋白質 |
| JP4168463B2 (ja) | 1996-12-05 | 2008-10-22 | 味の素株式会社 | Ｌ−リジンの製造法 |
| JPH11169182A (ja) | 1997-12-10 | 1999-06-29 | Mitsubishi Chemical Corp | コリネ型細菌内で蛋白質を効率よく培地中へ分泌させる変異型分泌装置遺伝子 |
| CN1299418A (zh) * | 1998-03-06 | 2001-06-13 | 味之素株式会社 | 编码青霉素结合蛋白的基因和生产l－谷氨酸的方法 |
| CN1170938C (zh) | 1998-09-25 | 2004-10-13 | 味之素株式会社 | 构建产生氨基酸的细菌的方法及通过发酵该经构建的产生氨基酸的细菌以制备氨基酸的方法 |
| JP2000262288A (ja) | 1999-03-16 | 2000-09-26 | Ajinomoto Co Inc | コリネ型細菌の温度感受性プラスミド |
| US20050244935A1 (en) * | 1999-06-25 | 2005-11-03 | Basf Ag | Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport |
| CN1367823A (zh) * | 1999-08-02 | 2002-09-04 | 阿彻·丹尼尔斯－米德兰公司 | 氨基酸生产的代谢工程 |
| BR0014059B1 (pt) | 1999-09-30 | 2013-02-05 | processo para produzir transglutaminase. | |
| US7723081B1 (en) | 2000-01-21 | 2010-05-25 | Ajinomoto Co., Inc. | Bacteria containing aspartate-semialdehyde dehydrogenase, phosphoenolpyruvate carboxylase, and transhydrogenase to produce L-lysine in escherichia, and methods of using same |
| CA2442679C (en) | 2001-03-30 | 2010-06-01 | Ajinomoto Co., Inc. | Methods for secretory production of proteins |
| WO2003040373A2 (en) | 2001-08-06 | 2003-05-15 | Degussa Ag | Production of l-lysine by genetically modified corynebacterium glutamicum strains |
| EP1548116A4 (en) | 2002-09-30 | 2006-04-05 | Ajinomoto Kk | PROCESS FOR PRODUCING A PROTEIN MARKED BY A STABLE ISOTOPE |
| JP4482938B2 (ja) * | 2003-03-07 | 2010-06-16 | 味の素株式会社 | 微生物トランスグルタミナーゼの製造法 |
| EP1649403A2 (en) | 2003-07-29 | 2006-04-26 | Ajinomoto Co., Inc. | Method for determining metabolic flux affecting substance production |
| US7807176B2 (en) * | 2004-03-19 | 2010-10-05 | Genomidea, Inc. | Polypeptide promoting vascular endothelial cell growth |
| JP4760711B2 (ja) | 2004-03-31 | 2011-08-31 | 味の素株式会社 | バチルス属又はエシェリヒア属に属する細菌を使用した発酵によるプリンヌクレオシド及びヌクレオチドの製造方法 |
| DK1748077T3 (da) | 2004-04-20 | 2013-04-08 | Ajinomoto Kk | Fremgangsmåde til fremstilling af protein |
| CN100554431C (zh) * | 2004-04-20 | 2009-10-28 | 味之素株式会社 | 生产蛋白质的方法 |
| WO2005113744A1 (ja) | 2004-05-20 | 2005-12-01 | Ajinomoto Co., Inc. | コハク酸生産菌及びコハク酸の製造方法 |
| JP4595506B2 (ja) | 2004-11-25 | 2010-12-08 | 味の素株式会社 | Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法 |
| AU2006219823A1 (en) * | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| US7723097B2 (en) | 2005-03-11 | 2010-05-25 | Archer-Daniels-Midland Company | Escherichia coli strains that over-produce L-threonine and processes for their production |
| RU2365622C2 (ru) | 2006-12-22 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПРОДУКЦИИ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Escherichia ИЛИ Bacillus |
| RU2355759C1 (ru) | 2007-08-14 | 2009-05-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ АРОМАТИЧЕСКОЙ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ГЕН ydiB, СПОСОБ ПОЛУЧЕНИЯ СЛОЖНОГО ЭФИРА НИЗШИХ АЛКИЛОВ АЛЬФА-L-АСПАРТИЛ-L-ФЕНИЛАЛАНИНА |
| WO2010005099A1 (ja) | 2008-07-09 | 2010-01-14 | 味の素株式会社 | アミノヒドロキシ安息香酸類の製造方法 |
| JP6136930B2 (ja) | 2011-11-02 | 2017-05-31 | 味の素株式会社 | タンパク質の分泌生産法 |
| IN2014CN04039A (enrdf_load_stackoverflow) | 2011-11-02 | 2015-10-23 | Ajinomoto Kk |
-
2012
- 2012-11-01 JP JP2013541834A patent/JP6136930B2/ja active Active
- 2012-11-01 IN IN4002CHN2014 patent/IN2014CN04002A/en unknown
- 2012-11-01 CN CN201280054138.9A patent/CN103946372B/zh active Active
- 2012-11-01 WO PCT/JP2012/078285 patent/WO2013065772A1/ja active Application Filing
- 2012-11-01 AU AU2012333515A patent/AU2012333515B2/en active Active
- 2012-11-01 EP EP12845191.1A patent/EP2774982B1/en active Active
-
2014
- 2014-04-29 US US14/264,600 patent/US9404138B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2774982A4 (en) | 2015-03-18 |
| EP2774982B1 (en) | 2017-06-21 |
| AU2012333515B2 (en) | 2015-07-16 |
| JP6136930B2 (ja) | 2017-05-31 |
| US9404138B2 (en) | 2016-08-02 |
| JPWO2013065772A1 (ja) | 2015-04-02 |
| AU2012333515A1 (en) | 2014-06-12 |
| EP2774982A1 (en) | 2014-09-10 |
| CN103946372B (zh) | 2016-06-08 |
| US20140234901A1 (en) | 2014-08-21 |
| CN103946372A (zh) | 2014-07-23 |
| WO2013065772A1 (ja) | 2013-05-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014CN04002A (enrdf_load_stackoverflow) | ||
| MX2018002705A (es) | Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas. | |
| IN2014CN04039A (enrdf_load_stackoverflow) | ||
| MX374736B (es) | Métodos para producir derivados de ácido graso omega-hidroxilados. | |
| MY166952A (en) | Biological methods for preparing a fatty dicarboxylic acid | |
| MY161726A (en) | Biological methods for preparing adipic acid | |
| IN2014CN04586A (enrdf_load_stackoverflow) | ||
| MX351565B (es) | Colageno 7 y metodos relacionados. | |
| MX379251B (es) | Producción mejorada de derivados de ácidos grasos. | |
| MY175182A (en) | Strain having enhanced l-valine productivity and l-valine production method using the same | |
| WO2014100504A3 (en) | Biological methods for preparing a fatty dicarboxylic acid | |
| MX368142B (es) | Metodo de clonacion, expresion y purificacion novedoso para la preparacion de ranibizumab. | |
| EP4458858A3 (en) | Method for the production of immunoglobulin single variable domains | |
| MX2014015667A (es) | Uso de polipeptidos que tienen actividad proteasa en alimentos para animales y detergentes. | |
| MX355890B (es) | Estrategia de múltiples copias para producción de alto título y alta pureza de proteínas de multi-subunidades tales como anticuerpos en microbios transformados tal como pichia pastoris. | |
| MY180645A (en) | Microbial production of fatty amines | |
| UA108343C2 (uk) | Спосіб одержання сквалену за допомогою дріжджів | |
| DK201370720A (en) | Mutant microorganism belonging to the genus trichoderma and method for producing protein using the same | |
| WO2012125626A3 (en) | Decorin compositions and use thereof | |
| EA028913B9 (ru) | Получение антител высокой чистоты в pichia pastoris | |
| WO2013019604A3 (en) | Protein production method | |
| EA201300884A1 (ru) | Способ получения нового антибактериального лекарственного средства на основе рекомбинантного полипептида | |
| AU2011301714B2 (en) | Synthetic gene for expressing Sm-14 in Pichia pastoris, methods for producing and purifying Sm-14 and the use thereof as a vaccine and diagnostic medium | |
| MX2014007760A (es) | Bacterias con unidades transcripcionales reconstruidas y los usos de las mismas. | |
| WO2011051820A3 (en) | Methods of increasing yields of pleuromutilins |