MX2018002705A - Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas. - Google Patents

Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas.

Info

Publication number
MX2018002705A
MX2018002705A MX2018002705A MX2018002705A MX2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A MX 2018002705 A MX2018002705 A MX 2018002705A
Authority
MX
Mexico
Prior art keywords
yeast strains
secretion
expression
high temperatures
heterologous proteins
Prior art date
Application number
MX2018002705A
Other languages
English (en)
Inventor
Argyros Aaron
F Rice Charles
Skinner Ryan
Barrett Trisha
Original Assignee
Lallemand Hungary Liquidity Man Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lallemand Hungary Liquidity Man Llc filed Critical Lallemand Hungary Liquidity Man Llc
Publication of MX2018002705A publication Critical patent/MX2018002705A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242—Fungal source
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Abstract

La presente descripción se refiere a cepas de levadura recombinante capaces de mantener su resistencia a temperatura elevada así como proteínas recombinantes expresadas a partir de esta. La presente descripción también proporciona métodos para utilizar la cepa de levadura recombinante para elaborar un producto de fermentación. La presente descripción procesa además un proceso para elaborar cepas de levadura recombinante capaces de mantener su resistencia a temperatura elevada.
MX2018002705A 2015-09-04 2016-08-29 Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas. MX2018002705A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562214412P 2015-09-04 2015-09-04
US201662299897P 2016-02-25 2016-02-25
PCT/IB2016/055162 WO2017037614A1 (en) 2015-09-04 2016-08-29 Yeast strains for the expression and secretion of heterologous proteins at high temperatures

Publications (1)

Publication Number Publication Date
MX2018002705A true MX2018002705A (es) 2018-12-19

Family

ID=56896745

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018002705A MX2018002705A (es) 2015-09-04 2016-08-29 Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas.

Country Status (7)

Country Link
US (1) US11332728B2 (es)
EP (1) EP3344762A1 (es)
CN (1) CN108291213A (es)
BR (1) BR112018004377A2 (es)
CA (1) CA2997380A1 (es)
MX (1) MX2018002705A (es)
WO (1) WO2017037614A1 (es)

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CN110177879A (zh) 2016-12-22 2019-08-27 拉勒曼德匈牙利流动性管理有限责任公司 重组酵母宿主细胞的亚硫酸盐耐受性
WO2018167670A1 (en) * 2017-03-13 2018-09-20 Lallemand Hungary Liquidity Management Llc Recombinant yeast host cells expressing cell-associated heterologous proteins
US20200224209A1 (en) 2017-05-23 2020-07-16 Lallemand Hungary Liquidity Management Llc Optimization of biomass-based fermentations
CA3093764A1 (en) * 2018-03-13 2019-09-19 Lallemand Hungary Liquidity Management Llc Inactivated yeast and yeast product for improving fermentation yield
CA3107110A1 (en) 2018-07-25 2020-01-30 Novozymes A/S Enzyme-expressing yeast for ethanol production
WO2020076697A1 (en) 2018-10-08 2020-04-16 Novozymes A/S Enzyme-expressing yeast for ethanol production
BR112021008130A2 (pt) 2018-11-02 2021-08-03 Lallemand Hungary Liquidity Management Llc. processo para prevenir ou limitar contaminação microbiana durante cultura contínua
CA3119639A1 (en) 2018-11-13 2020-05-22 Lallemand Hungary Liquidity Management Llc Synergistic bacterial and yeast combinations
EP3880693A1 (en) 2018-11-13 2021-09-22 Lallemand Hungary Liquidity Management LLC Modulation of formate oxidation by recombinant yeast host cell during fermentation
US20220220487A1 (en) 2018-11-13 2022-07-14 Lallemand Hungary Liquidity Management Llc Combined expression of trehalose producing and trehalose degrading enzymes
MX2021006660A (es) 2018-12-07 2021-07-07 Lallemand Hungary Liquidity Man Llc Modulacion de la generacion de nadph por medio de la celula hospedera de levadura recombinante durante la fermentacion.
US20220307036A1 (en) 2019-08-06 2022-09-29 Novozymes A/S Fusion proteins for improved enzyme expression
BR112022010438A2 (pt) * 2019-11-29 2022-10-11 Lallemand Hungary Liquidity Man Llc Processo para deslocamento de uma enzima exógena
WO2021104672A1 (en) 2019-11-29 2021-06-03 Lallemand Hungary Liquidity Management Llc Yeast expressing heterologous glucoamylase
US20230002794A1 (en) 2019-12-10 2023-01-05 Novozymes A/S Microorganism for improved pentose fermentation
WO2021163015A1 (en) 2020-02-10 2021-08-19 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
BR112022015805A2 (pt) 2020-02-10 2022-10-11 Novozymes As Variante de alfa-amilase de uma alfa-amilase genitora, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, composição, formulação de caldo inteiro ou composição de cultura de células, uso de uma alfa-amilase variante, processo de produção de um produto de fermentação a partir de material contendo amido e de um produto de xarope, e, planta transgênica, parte de planta ou célula de planta
CA3112754A1 (en) 2020-03-19 2021-09-19 Lallemand Hungary Liquidity Management Llc Yeast expressing glucoamylase with enhanced starch hydrolysis
CA3182342A1 (en) 2020-05-11 2021-11-18 Lallemand Hungary Liquidity Management Llc Recombinant yeast host cell expressing an hydrolase
CN112831485B (zh) * 2021-01-13 2023-08-15 云南师范大学 一种低温活性改良的外切菊粉酶突变体MutDR121EH9
WO2022162559A2 (en) 2021-01-26 2022-08-04 Danstar Ferment Ag Recombinant yeast host cell having enhanced growth rate
CN112662575B (zh) * 2021-01-28 2022-10-21 武汉轻工大学 高蛋白酶活性及高出酒率的扣囊复膜酵母菌、其组合物及应用
BR112023025624A2 (pt) 2021-06-07 2024-02-27 Novozymes As Célula de levedura recombinante, célula hospedeira recombinante, composição, cocultura, métodos de produção de um derivado de uma célula hospedeira recombinante e de produção de um produto de fermentação, e, uso de uma célula hospedeira recombinante
WO2023062542A2 (en) 2021-10-11 2023-04-20 Lallemand Hungary Liquidity Management Llc Recombinant yeast cell having increased pyruvate decarboxylase activity

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Also Published As

Publication number Publication date
WO2017037614A1 (en) 2017-03-09
CA2997380A1 (en) 2017-03-09
BR112018004377A2 (pt) 2019-04-09
CN108291213A (zh) 2018-07-17
US20180265853A1 (en) 2018-09-20
EP3344762A1 (en) 2018-07-11
US11332728B2 (en) 2022-05-17

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