IN2014CN02646A - - Google Patents

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Publication number
IN2014CN02646A
IN2014CN02646A IN2646CHN2014A IN2014CN02646A IN 2014CN02646 A IN2014CN02646 A IN 2014CN02646A IN 2646CHN2014 A IN2646CHN2014 A IN 2646CHN2014A IN 2014CN02646 A IN2014CN02646 A IN 2014CN02646A
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India
Prior art keywords
wnt
wnt pathway
signaling
diseases
disorders
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English (en)
Inventor
John Hood
Sunil Kumar Kc
Original Assignee
Samumed Llc
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Publication of IN2014CN02646A publication Critical patent/IN2014CN02646A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
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IN2646CHN2014 2011-09-14 2012-09-13 IN2014CN02646A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161534601P 2011-09-14 2011-09-14
US201261624646P 2012-04-16 2012-04-16
PCT/US2012/055172 WO2013040215A1 (en) 2011-09-14 2012-09-13 Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors

Publications (1)

Publication Number Publication Date
IN2014CN02646A true IN2014CN02646A (ru) 2015-08-07

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IN2646CHN2014 IN2014CN02646A (ru) 2011-09-14 2012-09-13

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US (6) US9221793B2 (ru)
EP (2) EP2755483B1 (ru)
JP (2) JP2014526510A (ru)
KR (1) KR102010611B1 (ru)
CN (2) CN109705097B (ru)
AU (2) AU2012308570B2 (ru)
BR (1) BR112014006127A2 (ru)
CA (1) CA2848659C (ru)
CL (1) CL2014000642A1 (ru)
CO (1) CO6940416A2 (ru)
CY (1) CY1122795T1 (ru)
DK (1) DK2755483T3 (ru)
ES (1) ES2711777T3 (ru)
HR (1) HRP20190281T1 (ru)
HU (1) HUE041576T2 (ru)
IL (1) IL231536A (ru)
IN (1) IN2014CN02646A (ru)
LT (1) LT2755483T (ru)
ME (1) ME03332B (ru)
MX (2) MX341504B (ru)
MY (1) MY184882A (ru)
PE (1) PE20141678A1 (ru)
PL (1) PL2755483T3 (ru)
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