IN2014CN02646A - - Google Patents

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Publication number
IN2014CN02646A
IN2014CN02646A IN2646CHN2014A IN2014CN02646A IN 2014CN02646 A IN2014CN02646 A IN 2014CN02646A IN 2646CHN2014 A IN2646CHN2014 A IN 2646CHN2014A IN 2014CN02646 A IN2014CN02646 A IN 2014CN02646A
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India
Prior art keywords
wnt
wnt pathway
signaling
diseases
disorders
Prior art date
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English (en)
Inventor
John Hood
Sunil Kumar Kc
Original Assignee
Samumed Llc
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Publication of IN2014CN02646A publication Critical patent/IN2014CN02646A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
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  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
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IN2646CHN2014 2011-09-14 2012-09-13 IN2014CN02646A (enrdf_load_stackoverflow)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161534601P 2011-09-14 2011-09-14
US201261624646P 2012-04-16 2012-04-16
PCT/US2012/055172 WO2013040215A1 (en) 2011-09-14 2012-09-13 Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors

Publications (1)

Publication Number Publication Date
IN2014CN02646A true IN2014CN02646A (enrdf_load_stackoverflow) 2015-08-07

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IN2646CHN2014 IN2014CN02646A (enrdf_load_stackoverflow) 2011-09-14 2012-09-13

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US (6) US9221793B2 (enrdf_load_stackoverflow)
EP (2) EP3473099A1 (enrdf_load_stackoverflow)
JP (2) JP2014526510A (enrdf_load_stackoverflow)
KR (1) KR102010611B1 (enrdf_load_stackoverflow)
CN (2) CN109705097B (enrdf_load_stackoverflow)
AU (2) AU2012308570B2 (enrdf_load_stackoverflow)
BR (1) BR112014006127A2 (enrdf_load_stackoverflow)
CA (1) CA2848659C (enrdf_load_stackoverflow)
CL (1) CL2014000642A1 (enrdf_load_stackoverflow)
CO (1) CO6940416A2 (enrdf_load_stackoverflow)
CY (1) CY1122795T1 (enrdf_load_stackoverflow)
DK (1) DK2755483T3 (enrdf_load_stackoverflow)
ES (1) ES2711777T3 (enrdf_load_stackoverflow)
HR (1) HRP20190281T1 (enrdf_load_stackoverflow)
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