IN2012DN03911A - - Google Patents

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Publication number
IN2012DN03911A
IN2012DN03911A IN3911DEN2012A IN2012DN03911A IN 2012DN03911 A IN2012DN03911 A IN 2012DN03911A IN 3911DEN2012 A IN3911DEN2012 A IN 3911DEN2012A IN 2012DN03911 A IN2012DN03911 A IN 2012DN03911A
Authority
IN
India
Prior art keywords
polyclonal antibodies
recombinant
recombinant polyclonal
quantitation
serum
Prior art date
Application number
Other languages
English (en)
Inventor
Torben Frandsen
Henrik Naested
Wagtbergsen Jette
Pernille Foged Jensen
Original Assignee
Symphogen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symphogen As filed Critical Symphogen As
Publication of IN2012DN03911A publication Critical patent/IN2012DN03911A/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • G01N33/6851Methods of protein analysis involving laser desorption ionisation mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Organic Chemistry (AREA)
  • Electrochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IN3911DEN2012 2009-10-09 2010-10-07 IN2012DN03911A (cs)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200901112 2009-10-09
US25623209P 2009-10-29 2009-10-29
PCT/DK2010/050258 WO2011042027A2 (en) 2009-10-09 2010-10-07 Multiplex quantitation of individual recombinant proteins in a mixture by signature peptides and mass spectrometry

Publications (1)

Publication Number Publication Date
IN2012DN03911A true IN2012DN03911A (cs) 2015-09-04

Family

ID=42166454

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3911DEN2012 IN2012DN03911A (cs) 2009-10-09 2010-10-07

Country Status (14)

Country Link
US (1) US20120264155A1 (cs)
EP (1) EP2486411A2 (cs)
JP (1) JP2013507603A (cs)
KR (1) KR20120100982A (cs)
CN (1) CN102687020A (cs)
AU (1) AU2010305150A1 (cs)
BR (1) BR112012007815A2 (cs)
CA (1) CA2776508A1 (cs)
IL (1) IL218821A0 (cs)
IN (1) IN2012DN03911A (cs)
MX (1) MX2012003538A (cs)
RU (1) RU2012118620A (cs)
WO (1) WO2011042027A2 (cs)
ZA (1) ZA201202431B (cs)

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EP2241875A1 (en) * 2009-04-14 2010-10-20 Koninklijke Philips Electronics N.V. Up-concentration of organic microobjects for microscopic imaging.
CN103608684B (zh) * 2011-05-12 2016-05-04 基因泰克公司 利用框架签名肽检测动物样品中的治疗性抗体的多重反应监测lc-ms/ms方法
WO2013019714A1 (en) 2011-07-29 2013-02-07 The Trustees Of Columbia University In The City Of New York Mems affinity sensor for continuous monitoring of analytes
WO2016022696A1 (en) * 2014-08-05 2016-02-11 The Trustees Of Columbia University In The City Of New York Method of isolating aptamers for minimal residual disease detection
US10627407B2 (en) 2015-03-12 2020-04-21 Mars, Incorporated Ultra high resolution mass spectrometry and methods of using the same
US10794916B2 (en) 2015-05-06 2020-10-06 Momenta Pharmaceuticals, Inc. Methods of glycoprotein analysis
CN105242050A (zh) * 2015-09-16 2016-01-13 同济大学 一种不同生理或病理条件下整体蛋白质的定量分析方法
CN105218671A (zh) * 2015-09-29 2016-01-06 李艳华 一种传染病病原体全人源化抗体的制备方法
GB201603291D0 (en) * 2016-02-25 2016-04-13 Binding Site Group The Ltd Antibodies
EP3433621A1 (en) * 2016-03-25 2019-01-30 H. Hoffnabb-La Roche Ag Multiplexed total antibody and antibody-conjugated drug quantification assay
EP3465221B1 (en) 2016-05-27 2020-07-22 H. Hoffnabb-La Roche Ag Bioanalytical method for the characterization of site-specific antibody-drug conjugates
CN107525934A (zh) * 2016-06-21 2017-12-29 张效龙 一种测定血液中抗体氨基酸序列的方法
US20210333288A1 (en) * 2016-08-17 2021-10-28 Momenta Pharmaceuticals, Inc. Glycan oxonium ion profiling of glycosylated proteins
CN108072728A (zh) * 2016-11-16 2018-05-25 中国科学院大连化学物理研究所 一种基于数据依赖性质谱扫描模式的谱图库建立方法及其应用
CN108956789A (zh) * 2017-05-17 2018-12-07 中国科学院大连化学物理研究所 一种血清中免疫球蛋白g糖肽的绝对定量分析方法
IL271499B2 (en) * 2017-08-01 2024-12-01 Amgen Inc Systems and methods for real-time polypeptide sample preparation for mass spectrometry analysis
US10615016B2 (en) * 2017-09-07 2020-04-07 Thermo Fisher Scientific (Bremen) Gmbh Determining isotope ratios using mass spectrometry
CN108226516B (zh) * 2017-11-30 2020-05-19 中国农业科学院北京畜牧兽医研究所 一种相对定量分析肉鸡脂肪酸去饱和酶fads1的方法
CN108169397B (zh) * 2017-11-30 2019-11-15 中国农业科学院北京畜牧兽医研究所 一种相对定量分析肉鸡谷胱甘肽s转移酶gsta2的方法
CN109900815B (zh) * 2017-12-08 2021-06-29 中国科学院大连化学物理研究所 血清中IgG糖肽的绝对定量分析
AU2019213647A1 (en) * 2018-01-31 2020-07-23 Regeneron Pharmaceuticals, Inc. Glucuronylation as acidic post-translational modification on therapeutic monoclonal antibodies
JP7205077B2 (ja) * 2018-05-10 2023-01-17 株式会社島津製作所 分析方法、処理装置、分析装置およびプログラム
CN110824096B (zh) * 2018-08-13 2022-11-29 齐鲁制药有限公司 一种蛋白错配二硫键的分析方法
CN110007019A (zh) * 2019-03-29 2019-07-12 绿城农科检测技术有限公司 一种同时定量检测母乳中三种抗体含量的方法
GB201910697D0 (en) * 2019-07-26 2019-09-11 Binding Site Group Ltd Lonisation control
JP2023514692A (ja) 2020-02-21 2023-04-07 ジェンマブ ビー.ブイ. 糖蛋白質の定量のための方法
CN111551739A (zh) * 2020-04-27 2020-08-18 杭州璞湃科技有限公司 一种免疫球蛋白a和免疫球蛋白a1的检测方法及其试剂盒
US20230228763A1 (en) * 2020-06-18 2023-07-20 Northwestern University Process for direct readout of immunoglobulins
JP7478040B2 (ja) 2020-06-25 2024-05-02 シスメックス株式会社 Aβペプチドの測定方法及びその方法に用いられる試薬組成物
CN111766323B (zh) * 2020-07-10 2022-06-14 中国检验检疫科学研究院 一种用于检测骆驼奶中掺入牛奶的特征肽组合及方法
CN113933409B (zh) * 2021-09-14 2023-11-14 上海中科新生命生物科技有限公司 基于液相色谱-质谱检测血清中特瑞普利单抗的方法
DE102022115561B4 (de) * 2022-06-22 2024-06-13 Bruker Daltonics GmbH & Co. KG Massenspektrometrische Bestimmung der Zelltoxizität
CN118221778A (zh) * 2024-04-25 2024-06-21 烟台大学 拟穴青蟹Scyreprocin蛋白的特征肽段及其在雌雄鉴别方面的应用
CN120399082B (zh) * 2025-07-04 2025-08-26 北京溯本源和生物科技有限公司 一种用于检测猫Cys-C蛋白的单克隆抗体组合及应用

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WO2003087834A2 (en) * 2002-04-08 2003-10-23 Affinium Pharmaceuticals, Inc. High throughput analysis of recombinant proteins in multi-well plates
CN101782581A (zh) 2002-10-03 2010-07-21 诺曼·利·安德森 用质谱法高灵敏度定量肽
EP1766388A4 (en) * 2004-06-09 2008-08-20 Anderson Forschung Group Llc STABLE ISOTOPES MARKED POLYPEPTIDE STANDARDS FOR PROTEIN QUANTIFICATION
DK1787126T3 (da) * 2004-07-20 2009-12-21 Symphogen As Fremgangsmåde til karakterisering af en polyklonal cellelinie
MX2007000644A (es) 2004-07-20 2007-03-28 Symphogen As Anticuerpo policlonal recombinante anti-rhesus d y metodos de fabricacion.
WO2006080396A1 (ja) * 2005-01-28 2006-08-03 Shionogi & Co., Ltd. 組換え蛋白質の定量法
JP2006300758A (ja) * 2005-04-21 2006-11-02 Apro Life Science Institute Inc 内部標準ペプチドを用いて生体由来試料に含まれる標的タンパク質を定量する方法
AU2006322445B2 (en) 2005-12-05 2011-05-12 Symphogen A/S Anti-orthopoxvirus recombinant polyclonal antibody
WO2007101441A1 (en) 2006-03-06 2007-09-13 Symphogen A/S Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections
KR101805140B1 (ko) * 2007-03-01 2017-12-05 심포젠 에이/에스 재조합 항-표피 성장 인자 수용체 항체 조성물
CN101679513A (zh) * 2007-03-06 2010-03-24 西福根有限公司 用于治疗呼吸道合胞病毒感染的重组抗体
US20090000419A1 (en) * 2007-06-29 2009-01-01 Harley-Davidson Motor Company Group, Inc. Handlebar assembly with axial locking feature

Also Published As

Publication number Publication date
US20120264155A1 (en) 2012-10-18
EP2486411A2 (en) 2012-08-15
AU2010305150A1 (en) 2012-04-05
WO2011042027A3 (en) 2011-09-22
ZA201202431B (en) 2012-12-27
KR20120100982A (ko) 2012-09-12
WO2011042027A2 (en) 2011-04-14
CN102687020A (zh) 2012-09-19
JP2013507603A (ja) 2013-03-04
RU2012118620A (ru) 2013-11-20
MX2012003538A (es) 2012-08-03
BR112012007815A2 (pt) 2018-03-20
IL218821A0 (en) 2012-06-28
CA2776508A1 (en) 2011-04-14

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