IL67103A - Ester and amide derivatives of 13,14-didehydroprostaglandins,their preparation and pharmaceutical compositions containing them - Google Patents

Ester and amide derivatives of 13,14-didehydroprostaglandins,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL67103A
IL67103A IL67103A IL6710382A IL67103A IL 67103 A IL67103 A IL 67103A IL 67103 A IL67103 A IL 67103A IL 6710382 A IL6710382 A IL 6710382A IL 67103 A IL67103 A IL 67103A
Authority
IL
Israel
Prior art keywords
didehydroprostaglandins
ester
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL67103A
Other languages
English (en)
Other versions
IL67103A0 (en
Inventor
Faustini Franco
Villa Vittoria
Gandolfi Carmelo
Di Salle Enrico
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of IL67103A0 publication Critical patent/IL67103A0/xx
Publication of IL67103A publication Critical patent/IL67103A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL67103A 1981-11-27 1982-10-28 Ester and amide derivatives of 13,14-didehydroprostaglandins,their preparation and pharmaceutical compositions containing them IL67103A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8135799 1981-11-27

Publications (2)

Publication Number Publication Date
IL67103A0 IL67103A0 (en) 1983-02-23
IL67103A true IL67103A (en) 1986-11-30

Family

ID=10526190

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67103A IL67103A (en) 1981-11-27 1982-10-28 Ester and amide derivatives of 13,14-didehydroprostaglandins,their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US4543353A (cg-RX-API-DMAC7.html)
JP (1) JPS58103356A (cg-RX-API-DMAC7.html)
AT (1) AT392964B (cg-RX-API-DMAC7.html)
AU (1) AU552847B2 (cg-RX-API-DMAC7.html)
BE (1) BE895137A (cg-RX-API-DMAC7.html)
CA (1) CA1237718A (cg-RX-API-DMAC7.html)
CH (1) CH656877A5 (cg-RX-API-DMAC7.html)
DE (1) DE3241399A1 (cg-RX-API-DMAC7.html)
DK (1) DK528982A (cg-RX-API-DMAC7.html)
FI (1) FI77442C (cg-RX-API-DMAC7.html)
FR (1) FR2517302A1 (cg-RX-API-DMAC7.html)
GB (1) GB2111986B (cg-RX-API-DMAC7.html)
IE (1) IE54347B1 (cg-RX-API-DMAC7.html)
IL (1) IL67103A (cg-RX-API-DMAC7.html)
IT (1) IT1153080B (cg-RX-API-DMAC7.html)
NL (1) NL8204611A (cg-RX-API-DMAC7.html)
SE (1) SE454588B (cg-RX-API-DMAC7.html)
SU (2) SU1301309A3 (cg-RX-API-DMAC7.html)
ZA (1) ZA827825B (cg-RX-API-DMAC7.html)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2130575B (en) * 1982-11-09 1985-12-11 Erba Farmitalia Amide derivatives of 13, 14-didehydro-cycloalkyl-prostaglandins
GB8329559D0 (en) * 1983-11-04 1983-12-07 Erba Farmitalia Furyl derivatives of 16-substituted prostaglandins preparations
US4877871A (en) * 1988-06-14 1989-10-31 Nabisco Brands, Inc. Synthesis of sucrose polyester
US5972991A (en) * 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
CN1350521A (zh) 1999-03-05 2002-05-22 宝洁公司 C16不饱和的fp选择性前列腺素类似物
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US9216183B2 (en) 2002-02-04 2015-12-22 Allergan, Inc. Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
US8758733B2 (en) 2002-02-04 2014-06-24 Allergan, Inc. Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
US7351404B2 (en) 2002-02-04 2008-04-01 Allergan, Inc. Method of enhancing hair growth
US9241918B2 (en) 2005-03-16 2016-01-26 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
NZ570191A (en) * 2006-01-24 2010-09-30 R Tech Ueno Ltd Soft-gelatin capsule formulation comprising a keto-prostaglandin compound
US20090238763A1 (en) * 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) * 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
WO2008041054A1 (en) * 2006-10-02 2008-04-10 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin penetration rates
US7507817B2 (en) * 2006-11-17 2009-03-24 Allergan, Inc. Prostaglandin prodrugs
DK2170826T3 (da) 2007-06-04 2022-07-11 Techfields Inc Nsaia-pro-lægemidler med meget høje hud- og membranpenetrationshastigheder og deres nye medicinske anvendelser
US7964595B2 (en) * 2008-01-18 2011-06-21 Allergan, Inc. Thiophenyl prostaglandin derivatives for treating glaucoma and ocular hypertension
EP2300439A1 (en) * 2008-05-09 2011-03-30 Allergan, Inc. Therapeutic substituted hydantoins, and related compounds
JP2011520811A (ja) * 2008-05-09 2011-07-21 アラーガン インコーポレイテッド 治療用の置換チアゾリジノン類、オキサゾリジノン類および関連化合物
US8722739B2 (en) * 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20100204335A1 (en) * 2008-12-01 2010-08-12 Allergan, Inc. Kit and composition for eyelash growth
KR20200022525A (ko) 2008-12-04 2020-03-03 충시 위 고투과력을 가진 조성물 및 이의 적용
JP5982287B2 (ja) * 2009-11-09 2016-08-31 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 発毛を刺激する組成物および方法
US9149484B2 (en) 2009-11-09 2015-10-06 Allergan, Inc. Compositions and methods for stimulating hair growth
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
US8859616B2 (en) 2011-01-21 2014-10-14 Allergan, Inc. Compounds and methods for enhancing hair growth
JP5925158B2 (ja) * 2013-06-04 2016-05-25 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ
JP6030168B2 (ja) * 2015-03-09 2016-11-24 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ
JP6306067B2 (ja) * 2016-01-08 2018-04-04 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE445717C (de) * 1924-05-16 1927-06-17 Chr Jonathan Sternkopf Vorrichtung zum Herstellen von Holzschliff fuer die Papier- u. dgl. Fabrikation
GB1425961A (en) * 1972-04-13 1976-02-25 Erba Carlo Spa Prostanoic acid derivatives
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
IL51877A (en) * 1976-06-01 1981-09-13 Carlo Erba Sa -nor-16-benzyl or phenoxy-13,14-dehydro-prostaglandins and process for their preparation
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
IT1088966B (it) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-dideidro-prostaglandine
SE434069B (sv) * 1980-07-09 1984-07-02 Mo Och Domsjoe Ab Forfarande for framstellning av slipmassa
SE446993B (sv) * 1980-07-09 1986-10-20 Mo Och Domsjoe Ab Forfarande for framstellning av blekt slipmassa

Also Published As

Publication number Publication date
IL67103A0 (en) 1983-02-23
ATA421482A (de) 1990-12-15
FI77442C (fi) 1989-03-10
GB2111986A (en) 1983-07-13
DE3241399A1 (de) 1983-06-01
IT1153080B (it) 1987-01-14
FR2517302A1 (fr) 1983-06-03
JPS58103356A (ja) 1983-06-20
FR2517302B1 (cg-RX-API-DMAC7.html) 1984-12-14
GB2111986B (en) 1985-05-15
SU1301309A3 (ru) 1987-03-30
IE822568L (en) 1983-05-27
AT392964B (de) 1991-07-25
IT8224327A1 (it) 1984-05-19
CH656877A5 (de) 1986-07-31
AU8979782A (en) 1983-06-02
CA1237718A (en) 1988-06-07
JPH0369899B2 (cg-RX-API-DMAC7.html) 1991-11-05
DE3241399C2 (cg-RX-API-DMAC7.html) 1990-10-31
SE454588B (sv) 1988-05-16
US4543353A (en) 1985-09-24
FI77442B (fi) 1988-11-30
AU552847B2 (en) 1986-06-26
DK528982A (da) 1983-05-28
SE8206731D0 (sv) 1982-11-25
FI824017A0 (fi) 1982-11-23
IE54347B1 (en) 1989-08-30
IT8224327A0 (it) 1982-11-19
SU1321372A3 (ru) 1987-06-30
SE8206731L (sv) 1983-05-28
ZA827825B (en) 1983-08-31
NL8204611A (nl) 1983-06-16
FI824017L (fi) 1983-05-28
BE895137A (fr) 1983-05-25

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