GB2130575B - Amide derivatives of 13, 14-didehydro-cycloalkyl-prostaglandins - Google Patents

Amide derivatives of 13, 14-didehydro-cycloalkyl-prostaglandins

Info

Publication number
GB2130575B
GB2130575B GB08231938A GB8231938A GB2130575B GB 2130575 B GB2130575 B GB 2130575B GB 08231938 A GB08231938 A GB 08231938A GB 8231938 A GB8231938 A GB 8231938A GB 2130575 B GB2130575 B GB 2130575B
Authority
GB
United Kingdom
Prior art keywords
didehydro
prostaglandins
cycloalkyl
amide derivatives
amide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08231938A
Other versions
GB2130575A (en
Inventor
Franco Faustini
Achille Panzeri
Walter Moretti
Carmelo Gandolfi
Roberto Ceserani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Priority to GB08231938A priority Critical patent/GB2130575B/en
Priority to DE19833338327 priority patent/DE3338327A1/en
Priority to BE0/211834A priority patent/BE898169A/en
Priority to JP58207657A priority patent/JPS59101459A/en
Publication of GB2130575A publication Critical patent/GB2130575A/en
Application granted granted Critical
Publication of GB2130575B publication Critical patent/GB2130575B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
GB08231938A 1982-11-09 1982-11-09 Amide derivatives of 13, 14-didehydro-cycloalkyl-prostaglandins Expired GB2130575B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB08231938A GB2130575B (en) 1982-11-09 1982-11-09 Amide derivatives of 13, 14-didehydro-cycloalkyl-prostaglandins
DE19833338327 DE3338327A1 (en) 1982-11-09 1983-10-21 AMIDE DERIVATIVES OF 13,14-DIDEHYDRO-CYCLOALKYL-PROSTA-GLANDINES
BE0/211834A BE898169A (en) 1982-11-09 1983-11-07 Amide derivatives of 13,14-didehydro-cycloalkyl-prostaglandins.
JP58207657A JPS59101459A (en) 1982-11-09 1983-11-07 Prostaglandin derivative, manufacture and pharmaceutical composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08231938A GB2130575B (en) 1982-11-09 1982-11-09 Amide derivatives of 13, 14-didehydro-cycloalkyl-prostaglandins

Publications (2)

Publication Number Publication Date
GB2130575A GB2130575A (en) 1984-06-06
GB2130575B true GB2130575B (en) 1985-12-11

Family

ID=10534131

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08231938A Expired GB2130575B (en) 1982-11-09 1982-11-09 Amide derivatives of 13, 14-didehydro-cycloalkyl-prostaglandins

Country Status (4)

Country Link
JP (1) JPS59101459A (en)
BE (1) BE898169A (en)
DE (1) DE3338327A1 (en)
GB (1) GB2130575B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1088966B (en) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-didehydro-prostaglandins
US4543353A (en) * 1981-11-27 1985-09-24 Farmitalia Carlo Erba S.P.A. Ester and amide derivatives of 13,14-didehydro prostaglandins

Also Published As

Publication number Publication date
JPS59101459A (en) 1984-06-12
BE898169A (en) 1984-05-07
DE3338327A1 (en) 1984-05-10
GB2130575A (en) 1984-06-06

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee