IL59558A - 9-aminoalkylfluorenes,their preparation and pharmaceutical compositions comprising them - Google Patents

9-aminoalkylfluorenes,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL59558A
IL59558A IL59558A IL5955880A IL59558A IL 59558 A IL59558 A IL 59558A IL 59558 A IL59558 A IL 59558A IL 5955880 A IL5955880 A IL 5955880A IL 59558 A IL59558 A IL 59558A
Authority
IL
Israel
Prior art keywords
aminoalkylfluorenes
preparation
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
IL59558A
Other languages
English (en)
Other versions
IL59558A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL59558A0 publication Critical patent/IL59558A0/xx
Publication of IL59558A publication Critical patent/IL59558A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A41—WEARING APPAREL
    • A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00—Materials specially adapted for outerwear
    • A41D31/04—Materials specially adapted for outerwear characterised by special function or use
    • A41D31/10—Impermeable to liquids, e.g. waterproof; Liquid-repellent
    • A41D31/102—Waterproof and breathable
    • A—HUMAN NECESSITIES
    • A41—WEARING APPAREL
    • A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00—Materials specially adapted for outerwear
    • A41D31/04—Materials specially adapted for outerwear characterised by special function or use
    • A41D31/18—Elastic
    • A41D31/185—Elastic using layered materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Textile Engineering (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL59558A 1979-03-12 1980-03-09 9-aminoalkylfluorenes,their preparation and pharmaceutical compositions comprising them IL59558A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1953379A 1979-03-12 1979-03-12

Publications (2)

Publication Number Publication Date
IL59558A0 IL59558A0 (en) 1980-06-30
IL59558A true IL59558A (en) 1984-05-31

Family

ID=21793707

Family Applications (1)

Application Number Title Priority Date Filing Date
IL59558A IL59558A (en) 1979-03-12 1980-03-09 9-aminoalkylfluorenes,their preparation and pharmaceutical compositions comprising them

Country Status (40)

Country Link
US (1) US4277495A (fr)
EP (1) EP0018076B1 (fr)
JP (1) JPS55124743A (fr)
KR (2) KR840000279B1 (fr)
AR (6) AR228851A1 (fr)
AT (4) AT370407B (fr)
AU (1) AU527992B2 (fr)
BE (1) BE882166A (fr)
CA (1) CA1136624A (fr)
CH (1) CH643234A5 (fr)
CS (4) CS214698B2 (fr)
CY (1) CY1345A (fr)
DD (1) DD149511A5 (fr)
DE (1) DE3064872D1 (fr)
DK (1) DK158658C (fr)
EG (1) EG14592A (fr)
ES (5) ES489470A0 (fr)
FI (3) FI67211C (fr)
FR (2) FR2460287A1 (fr)
GB (1) GB2046257B (fr)
GR (1) GR68035B (fr)
GT (1) GT198062477A (fr)
HK (1) HK101086A (fr)
HU (1) HU179837B (fr)
IE (1) IE49553B1 (fr)
IL (1) IL59558A (fr)
IT (1) IT1140772B (fr)
LU (1) LU82236A1 (fr)
MA (1) MA18763A1 (fr)
MY (1) MY8700080A (fr)
NZ (1) NZ193078A (fr)
OA (1) OA06486A (fr)
PH (1) PH15594A (fr)
PL (1) PL122643B1 (fr)
PT (1) PT70927A (fr)
RO (2) RO79822A (fr)
SG (1) SG72286G (fr)
SU (2) SU1022656A3 (fr)
YU (1) YU65680A (fr)
ZA (1) ZA801422B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4212337A (en) * 1978-03-31 1980-07-15 Union Carbide Corporation Closure fastening device
US4452745A (en) * 1981-02-06 1984-06-05 Eli Lilly And Company 9-Aminoalkylfluorenes
US4484352A (en) * 1983-02-07 1984-11-20 Katzin Lawrence F Reclosable plastic bag
US4552982A (en) * 1983-08-01 1985-11-12 Eli Lilly And Company Synthesis of 9-carbamoyl-9-(3-aminopropyl)fluorenes
US4508735A (en) * 1983-09-21 1985-04-02 Eli Lilly And Company Anti-arrhythmic N-alkanoylaminoalkyl fluorenes
US4486592A (en) * 1983-10-19 1984-12-04 Eli Lilly And Company 9-Carbamoylfluorene derivatives
US4585894A (en) * 1983-10-19 1986-04-29 Eli Lilly And Company Process for producing 9-carbamoyl fluorene derivatives
FI844067L (fi) * 1983-10-19 1985-04-20 Lilly Co Eli Foerfarande foer framstaellning av 9-karbamoylfluorenderivat.
DE3444837A1 (de) * 1984-12-08 1986-06-12 Basf Ag, 6700 Ludwigshafen 10,11-dihydro-5h-dibenzo(a,d)cycloheptadien- derivate, ihre herstellung und verwendung
GB9304189D0 (en) * 1993-03-02 1993-04-21 Sturmey Archer Ltd Epicyclic change speed gear hubs
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5631203A (en) * 1995-05-04 1997-05-20 Phillips Petroleum Company Metallocene compounds and preparation thereof containing terminal alkynes
CA2236684A1 (fr) * 1996-01-16 1997-07-24 William A. Slusarchyk Composes aromatiques a conformation restreinte servant d'inhibiteurs de la proteine de transfert de triglyceride microsomique et procede associe
US5760246A (en) * 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB736372A (en) * 1953-05-06 1955-09-07 Miles Lab Fluorene derivatives
FR1345419A (fr) * 1962-12-21 1963-12-06 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés basiques du fluorène et des sels de ces dérivés
NL287095A (fr) 1962-12-21 1965-02-25
DE1203253B (de) * 1963-02-09 1965-10-21 Boehringer & Soehne Gmbh Verfahren zur Herstellung basischer Fluorenderivate und ihrer Salze
FR1482727A (fr) * 1965-06-10 1967-05-26 Upjohn Co 9-(2-amino-1-méthyléthyl) fluoren-9-ols et leur procédé de fabrication
GB1211459A (en) * 1967-05-10 1970-11-04 Abbott Lab Hydroxy amines
US3660485A (en) * 1970-10-05 1972-05-02 Searle & Co Fluorene-9-carboxylic acid hydrazides
US3843657A (en) * 1972-12-08 1974-10-22 Searle & Co 9-dialkylamin oalkyl-n-substituted fluorene-9-carboxamides

Also Published As

Publication number Publication date
PH15594A (en) 1983-02-28
HK101086A (en) 1987-01-02
IE49553B1 (en) 1985-10-30
YU65680A (en) 1983-02-28
ZA801422B (en) 1981-10-28
AT368125B (de) 1982-09-10
SG72286G (en) 1987-03-27
ES8201943A1 (es) 1982-01-01
FI800735A (fi) 1980-09-13
FR2457278A1 (fr) 1980-12-19
ES497300A0 (es) 1982-01-01
FI67211B (fi) 1984-10-31
GR68035B (fr) 1981-10-27
FR2457278B1 (fr) 1984-06-29
DK103380A (da) 1980-09-13
MY8700080A (en) 1987-12-31
CS214700B2 (en) 1982-05-28
JPS6314702B2 (fr) 1988-04-01
KR830001860A (ko) 1983-05-19
FI70006C (fi) 1986-09-12
ES497302A0 (es) 1982-01-01
JPS55124743A (en) 1980-09-26
IL59558A0 (en) 1980-06-30
FI840921A (fi) 1984-03-07
ATA134480A (de) 1982-08-15
HU179837B (en) 1982-12-28
CA1136624A (fr) 1982-11-30
FI69299C (fi) 1986-01-10
SU1015820A3 (ru) 1983-04-30
MA18763A1 (fr) 1980-10-01
CY1345A (en) 1987-01-16
RO85074A (fr) 1984-08-17
SU1022656A3 (ru) 1983-06-07
NZ193078A (en) 1981-11-19
CH643234A5 (fr) 1984-05-30
ES497301A0 (es) 1982-01-01
BE882166A (fr) 1980-09-11
ES8201947A1 (es) 1982-01-01
IT1140772B (it) 1986-10-10
KR840001836B1 (ko) 1984-10-22
CS214696B2 (en) 1982-05-28
DK158658C (da) 1990-12-31
DK158658B (da) 1990-07-02
ATA114181A (de) 1982-01-15
CS214699B2 (en) 1982-05-28
PT70927A (en) 1980-04-01
AR229402A1 (es) 1983-08-15
AR228059A1 (es) 1983-01-14
KR840000279B1 (ko) 1984-03-13
LU82236A1 (fr) 1980-06-06
FR2460287A1 (fr) 1981-01-23
AU5630180A (en) 1980-09-18
AU527992B2 (en) 1983-03-31
ES497303A0 (es) 1982-01-01
DD149511A5 (de) 1981-07-15
EG14592A (en) 1985-03-31
EP0018076A1 (fr) 1980-10-29
IE800494L (en) 1980-09-12
ES8104186A1 (es) 1981-04-16
FI67211C (fi) 1985-02-11
RO79822A (fr) 1983-02-01
ES8201945A1 (es) 1982-01-01
DE3064872D1 (en) 1983-10-27
EP0018076B1 (fr) 1983-09-21
FI840920A (fi) 1984-03-07
AR228851A1 (es) 1983-04-29
GB2046257B (en) 1983-10-19
IT8020502A0 (it) 1980-03-11
FI840921A0 (fi) 1984-03-07
AT370407B (de) 1983-03-25
ES8201946A1 (es) 1982-01-01
GB2046257A (en) 1980-11-12
OA06486A (fr) 1981-07-31
ES489470A0 (es) 1981-04-16
PL122643B1 (en) 1982-08-31
US4277495A (en) 1981-07-07
FI840920A0 (fi) 1984-03-07
AT368131B (de) 1982-09-10
FI69299B (fi) 1985-09-30
AR225526A1 (es) 1982-03-31
FR2460287B1 (fr) 1983-03-11
GT198062477A (es) 1981-09-02
CS214698B2 (en) 1982-05-28
AR227318A1 (es) 1982-10-15
ATA114081A (de) 1982-01-15
PL222600A1 (fr) 1980-12-15
AR230983A1 (es) 1984-08-31
ATA113981A (de) 1982-01-15
FI70006B (fi) 1986-01-31
AT368130B (de) 1982-09-10

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Legal Events

Date Code Title Description
RH Patent void