IL160798A0 - Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations - Google Patents

Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations

Info

Publication number
IL160798A0
IL160798A0 IL16079804A IL16079804A IL160798A0 IL 160798 A0 IL160798 A0 IL 160798A0 IL 16079804 A IL16079804 A IL 16079804A IL 16079804 A IL16079804 A IL 16079804A IL 160798 A0 IL160798 A0 IL 160798A0
Authority
IL
Israel
Prior art keywords
rifaximin
processes
production
medicinal preparations
polymorphous forms
Prior art date
Application number
IL16079804A
Other languages
English (en)
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33187382&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL160798(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Publication of IL160798A0 publication Critical patent/IL160798A0/xx

Links

Classifications

    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00—Heating by electric, magnetic or electromagnetic fields
    • H05B6/02—Induction heating
    • H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
    • H05B6/12—Cooking devices
    • H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
    • H05B6/1236—Cooking devices induction cooking plates or the like and devices to be used in combination with them adapted to induce current in a coil to supply power to a device and electrical heating devices powered in this way
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00—Heating by electric, magnetic or electromagnetic fields
    • H05B6/02—Induction heating
    • H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
    • H05B6/12—Cooking devices
    • H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
    • H05B6/1245—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements
    • H05B6/1263—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements using coil cooling arrangements

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
IL16079804A 2003-11-07 2004-03-09 Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations IL160798A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002144A ITMI20032144A1 (it) 2003-11-07 2003-11-07 Forme polimorfe di rifaximina, processi per ottenerle e

Publications (1)

Publication Number Publication Date
IL160798A0 true IL160798A0 (en) 2004-08-31

Family

ID=33187382

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16079804A IL160798A0 (en) 2003-11-07 2004-03-09 Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations
IL174271A IL174271A (en) 2003-11-07 2006-03-12 Purified alpha, beta, gamma polymorphs of rifaximin antibiotics and process for their production

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL174271A IL174271A (en) 2003-11-07 2006-03-12 Purified alpha, beta, gamma polymorphs of rifaximin antibiotics and process for their production

Country Status (38)

Country Link
US (5) US7045620B2 (es)
EP (6) EP1557421B1 (es)
JP (5) JP2005139161A (es)
KR (4) KR20050043589A (es)
CN (4) CN1613858A (es)
AR (3) AR043547A1 (es)
AT (3) ATE421965T1 (es)
AU (2) AU2004200964A1 (es)
BR (2) BRPI0402382A (es)
CA (2) CA2460384A1 (es)
CL (1) CL2004000498A1 (es)
CO (1) CO5560083A1 (es)
CY (3) CY1108017T1 (es)
DE (4) DE602004019298D1 (es)
DK (3) DK1557421T3 (es)
ES (3) ES2320161T3 (es)
HK (3) HK1092151A1 (es)
HR (2) HRP20040265A2 (es)
IL (2) IL160798A0 (es)
IT (1) ITMI20032144A1 (es)
JO (1) JO2470B1 (es)
MA (1) MA27069A1 (es)
MD (1) MD3653G8 (es)
ME (1) ME00424B (es)
MX (2) MXPA04002353A (es)
NO (1) NO334950B1 (es)
NZ (1) NZ531622A (es)
PL (3) PL1676847T3 (es)
PT (3) PT1557421E (es)
RS (4) RS54569B1 (es)
RU (1) RU2270200C2 (es)
SI (3) SI1676847T1 (es)
TN (2) TNSN04044A1 (es)
TW (1) TWI285107B (es)
UA (1) UA86384C2 (es)
WO (1) WO2005044823A2 (es)
YU (1) YU24804A (es)
ZA (1) ZA200401948B (es)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861053B1 (en) * 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US7923553B2 (en) * 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US7902206B2 (en) * 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7906542B2 (en) * 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
SI1698630T1 (sl) * 2005-03-03 2015-01-30 Alfa Wassermann S.P.A. Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih
ITBO20050123A1 (it) * 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
DK2054066T3 (en) 2006-08-02 2015-06-08 Salix Pharmaceuticals Inc METHODS OF TREATMENT OF RADIATE ENTERITIS
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
EP2069363B1 (en) * 2006-09-22 2013-03-20 Cipla Ltd. Rifaximin in an amorphous form
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
EP2011486B2 (en) * 2007-07-06 2015-08-12 Lupin Ltd. Pharmaceutical compositions of rifaximin
US8383151B2 (en) * 2007-07-06 2013-02-26 Lupin Limited Pharmaceutical compositions of rifaximin
AU2016203925B2 (en) * 2007-07-06 2016-10-20 Lupin Limited Pharmaceutical compositions of rifaximin
US7709634B2 (en) * 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
US8486956B2 (en) * 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
ME01032B (me) * 2008-02-25 2012-10-20 Salix Pharmaceuticals Ltd FORME RIFAKSIMINA l NJIHOVA UPOTREBA
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
US8309569B2 (en) 2008-02-26 2012-11-13 Salix Pharmaceuticals, Ltd. Methods for treating diarrhea-associated irritable bowel syndrome
US20090324736A1 (en) 2008-05-07 2009-12-31 Salix Pharmaceuticals, Ltd. Methods of treating bowel diseases by administering a bowel cleanser and an antibiotic
CA2736285C (en) 2008-09-26 2016-08-23 Aska Pharmaceutical Co., Ltd. Agent for preventing and/or treating functional gastrointestinal disorder
US20100317681A1 (en) * 2009-06-15 2010-12-16 Salix Pharmaceuticals, Ltd. Modulation of systemic exposure to rifaximin
US7928115B2 (en) * 2008-10-02 2011-04-19 Salix Pharmaceuticals, Ltd. Methods of treating travelers diarrhea and hepatic encephalopathy
US20110035232A1 (en) 2008-10-02 2011-02-10 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
HUE065491T2 (hu) 2008-10-02 2024-05-28 Salix Pharmaceuticals Ltd A hepatikus enkefalopátia kezelése rifaximin alkalmazásával
KR20110107806A (ko) 2008-12-10 2011-10-04 시플라 리미티드 리팍시민 복합체
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
MX2011012829A (es) * 2009-06-02 2012-02-28 Salix Pharmaceuticals Ltd Metodos para tratar encefalopatia hepatica.
MX2012002895A (es) 2009-09-13 2012-05-22 Salix Pharmaceuticals Ltd Metodos para tratar el sindrome de intestino irritado (ibs).
KR102456997B1 (ko) * 2009-10-27 2022-10-19 루핀 리미티드 리팍시민의 고형 분산물
WO2011061748A1 (en) * 2009-11-19 2011-05-26 Strides Arcolab Limited Rifaximin premix
NZ600362A (en) 2009-11-23 2014-08-29 Cipla Ltd Topical foam composition
WO2011080691A1 (en) 2009-12-28 2011-07-07 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
EP3650022A1 (en) 2010-02-18 2020-05-13 Salix Pharmaceuticals, Ltd. Methods for treating rifampin resistant clostridium difficilis infections
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
CN103269587A (zh) * 2010-06-03 2013-08-28 萨利克斯药品有限公司 利福昔明的新形式及其用途
US8883795B2 (en) * 2010-06-16 2014-11-11 Apotex Pharmachem Inc. Polymorphic forms of Rifaximin
CA2804635C (en) 2010-07-12 2019-09-10 Salix Pharmaceuticals, Ltd. Formulations of rifaximin and uses thereof
WO2012035544A2 (en) 2010-09-13 2012-03-22 Sequent Scientific Ltd. A novel polymorphic form of rifaximin and process for its preparation
IT1403847B1 (it) 2010-09-22 2013-11-08 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina e loro uso.
WO2012060675A1 (es) * 2010-11-05 2012-05-10 Interquim, S.A. De C.V. Proceso para la preparación de rifaximina amorfa
WO2012076832A1 (en) * 2010-12-09 2012-06-14 Cipla Limited Suppositories comprising rifaximin
AU2012214239B2 (en) 2011-02-11 2016-06-30 Salix Pharmaceuticals, Ltd. Forms of Rifaximin and uses thereof
CA2834829A1 (en) 2011-05-02 2012-11-08 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
WO2012155981A1 (en) 2011-05-19 2012-11-22 Friulchem Spa New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
ITMI20110890A1 (it) * 2011-05-19 2012-11-20 A M S A Anonima Materie Sint & Affini S P A Polimorfo di rifaximina e processo per la sua preparazione
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
WO2013067394A1 (en) 2011-11-02 2013-05-10 Salix Pharmaceuticals, Ltd Methods for treating irritable bowel syndrome (ibs) and infections
JP2013184902A (ja) * 2012-03-06 2013-09-19 Aska Pharmaceutical Co Ltd リファキシミン含有結晶
CA2876737A1 (en) * 2012-06-13 2013-12-19 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
WO2014091432A1 (en) 2012-12-12 2014-06-19 Ranbaxy Laboratories Limited Pharmaceutical compositions of rifaximin
US20160038468A1 (en) 2013-03-15 2016-02-11 Alfa Wassermann S.P.A. Rifaximin for use in the treating of vaginal infections
JP2016516988A (ja) 2013-03-15 2016-06-09 アルファ ワッセルマン ソシエタ ペル アチオニＡｌｆａ Ｗａｓｓｅｒｍａｎｎ Ｓ．Ｐ．Ａ． 膣感染症を診断するための方法
AU2014252219B2 (en) 2013-04-12 2018-11-22 Alfasigma S.P.A. NSAID administration and related compositions, methods and systems.
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
EP2927235B1 (en) 2014-03-31 2017-02-08 Euticals S.P.A. Polymorphic mixture of rifaximin and its use for the preparation of solid formulations
US9765088B2 (en) 2014-04-19 2017-09-19 Granules India Limited Process for the preparation of rifamycin derivatives
WO2015171493A1 (en) 2014-05-04 2015-11-12 Salix Pharmaceuticals, Inc. Ibs microbiota and uses thereof
RS59250B1 (sr) 2014-05-12 2019-10-31 Alfasigma Spa Novi solvatni kristalni oblik rifaksimina, njegova proizvodnja, kompozicije i upotreba
CN106999477B (zh) * 2014-06-30 2020-04-10 萨利克斯药品公司 用于重复治疗肠易激综合征(ibs)的方法
CN104083324B (zh) * 2014-07-10 2017-05-10 青岛动保国家工程技术研究中心有限公司 一种利福昔明的兽用悬乳剂及其制备方法和应用
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
CN104274391B (zh) * 2014-10-08 2017-02-01 哈尔滨坤盟医药科技有限公司 一种含利福昔明的药物制剂
WO2017021975A1 (en) * 2015-08-06 2017-02-09 Msn Laboratories Private Limited Process for the preparation of crystalline forms of rifaximin
ES2700423T3 (es) 2016-03-24 2019-02-15 Sandoz Ag Composición farmacéutica que contiene rifaximina alfa y delta
EP3536311B1 (en) 2016-03-24 2021-12-22 Sandoz AG Storage stable composition comprising rifaximin alpha
US9988398B2 (en) * 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
WO2018064472A1 (en) 2016-09-30 2018-04-05 Salix Pharmaceuticals, Ltd. Solid dispersion forms of rifaximin
CN106632396B (zh) * 2017-01-06 2019-01-11 成都樵枫科技发展有限公司 γ晶型利福昔明的制备方法和用途
AU2018211305B2 (en) 2017-04-26 2019-07-25 Sandoz Ag Oral dosage form comprising rifaximin in form beta
EP3645539B1 (en) 2017-06-26 2021-04-07 Biofer S.p.A. Pyrido-imidazo rifamycin derivatives as antibacterial agent
WO2020245214A1 (en) 2019-06-03 2020-12-10 Bausch Health Ireland Limited Use of methylnaltrexone and rifaximin for treatment of increased gut permeability or associated disorders
AU2020355603A1 (en) 2019-09-24 2022-03-17 Bausch Health Ireland Limited Rifaximin liquid formulations
WO2021191312A1 (en) 2020-03-24 2021-09-30 Bausch Health Ireland Limited Methods of treating covid-19 with rifaximin
WO2021229480A1 (en) * 2020-05-15 2021-11-18 Atra Pharmaceuticals Limited Polymorph of rifaximin, process for the preparation thereof and pharmaceutical composition containing rifaximin
EP4171520A1 (en) 2020-06-26 2023-05-03 Bausch Health Ireland Limited Targeted release rifaximin compositions
US20230398102A1 (en) 2020-10-29 2023-12-14 Bausch Health Ireland Limited Rifaximin liquid formulations for use inthe treatment of sickle cell disease

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4241785A (en) * 1978-07-24 1980-12-30 Peerless Of America, Inc. Heat exchangers and method of making same
IT1154655B (it) * 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica
IT1199374B (it) * 1984-05-15 1988-12-30 Alfa Farmaceutici Spa Processo per la preparazione di pirido-imidazo-rifamicine
CA1215976A (en) 1984-05-15 1986-12-30 Vincenzo Cannata New process for the synthesis of imidazo rifamycins
IT1199413B (it) 1984-09-26 1988-12-30 Alfa Farmaceutici Spa Processo per la preparazione di pirido-imidazo-rifamicine
GB8816620D0 (en) * 1988-07-13 1988-08-17 Lepetit Spa Rifapentine hydrohalides
EP0536197B1 (en) * 1990-06-29 1995-07-26 GRUPPO LEPETIT S.p.A. Pure crystalline form of rifapentine
WO2001051919A2 (en) * 2000-01-07 2001-07-19 Transform Pharmaceuticals, Inc. High-throughput formation, identification, and analysis of diverse solid-forms
UA75365C2 (en) * 2000-08-16 2006-04-17 Bristol Myers Squibb Co Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon
EP1330427A1 (en) * 2000-10-31 2003-07-30 Ciba SC Holding AG Crystalline forms of venlafaxine hydrochloride
IL156055A0 (en) * 2000-11-30 2003-12-23 Teva Pharma Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US20050262269A1 (en) 2004-05-20 2005-11-24 Pike Jimmy D System and method for information handling system PCI express advanced switching
SI1698630T1 (sl) 2005-03-03 2015-01-30 Alfa Wassermann S.P.A. Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih
EP2069363B1 (en) * 2006-09-22 2013-03-20 Cipla Ltd. Rifaximin in an amorphous form
WO2008115572A1 (en) 2007-03-21 2008-09-25 Theraquest Biosciences, Inc. Methods and compositions of nsaids
ITMI20071241A1 (it) 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
US8383151B2 (en) * 2007-07-06 2013-02-26 Lupin Limited Pharmaceutical compositions of rifaximin
EP2011486B2 (en) 2007-07-06 2015-08-12 Lupin Ltd. Pharmaceutical compositions of rifaximin
US7709634B2 (en) * 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
WO2009047801A1 (en) 2007-10-10 2009-04-16 Lupin Limited Therapeutic combinations and compositions for the treatment of gastrointestinal disorders
ME01032B (me) 2008-02-25 2012-10-20 Salix Pharmaceuticals Ltd FORME RIFAKSIMINA l NJIHOVA UPOTREBA

Also Published As

Publication number Publication date
MD3653G8 (ro) 2016-08-31
CN101260115A (zh) 2008-09-10
CY1108964T1 (el) 2014-07-02
EP1676847A1 (en) 2006-07-05
EP1676848A1 (en) 2006-07-05
RU2004108953A (ru) 2005-10-27
YU24804A (sh) 2006-08-17
ES2244364T1 (es) 2005-12-16
CN1613858A (zh) 2005-05-11
NO20061110L (no) 2006-04-19
JP5199576B2 (ja) 2013-05-15
US8404704B2 (en) 2013-03-26
CL2004000498A1 (es) 2005-03-11
US20050272754A1 (en) 2005-12-08
AR081991A2 (es) 2012-10-31
US7045620B2 (en) 2006-05-16
ATE421966T1 (de) 2009-02-15
CY1108017T1 (el) 2013-09-04
EP1676848B1 (en) 2009-01-28
DK1676847T3 (da) 2009-05-11
PL1676847T3 (pl) 2009-07-31
CN1886408B (zh) 2010-06-09
TWI285107B (en) 2007-08-11
KR20060110737A (ko) 2006-10-25
EP1682556A2 (en) 2006-07-26
JP2007509904A (ja) 2007-04-19
RU2270200C2 (ru) 2006-02-20
SI1676848T1 (sl) 2009-06-30
ES2320160T4 (es) 2011-03-09
KR20050043589A (ko) 2005-05-11
KR20070113327A (ko) 2007-11-28
PT1676847E (pt) 2009-04-09
DE04005541T1 (de) 2005-12-29
EP1557421A1 (en) 2005-07-27
AU2004287601A1 (en) 2005-05-19
NO334950B1 (no) 2014-08-04
HRP20060093A2 (en) 2006-05-31
ES2320161T3 (es) 2009-05-19
MA27069A1 (fr) 2004-12-20
JP2011057698A (ja) 2011-03-24
CA2460384A1 (en) 2005-05-07
MD3653F2 (en) 2008-07-31
CY1108909T1 (el) 2014-07-02
EP2210893A1 (en) 2010-07-28
MD20060080A (en) 2006-11-30
HK1092151A1 (en) 2007-02-02
AU2004200964A1 (en) 2005-05-26
HK1073657A1 (en) 2005-10-14
AR081992A2 (es) 2012-10-31
TNSN04044A1 (en) 2006-06-01
CA2538546C (en) 2011-04-19
JP2005139161A (ja) 2005-06-02
EP1676847B1 (en) 2009-01-28
CN1886408A (zh) 2006-12-27
AR043547A1 (es) 2005-08-03
RS20060168A (en) 2008-09-29
DE602004006367D1 (de) 2007-06-21
BRPI0407149A8 (pt) 2019-01-15
DE602004019296D1 (de) 2009-03-19
US20120059023A1 (en) 2012-03-08
EP2208730A1 (en) 2010-07-21
ES2320160T3 (es) 2009-05-19
HRP20040265A2 (en) 2004-12-31
MXPA04002353A (es) 2005-05-11
HK1092150A1 (en) 2007-02-02
RS20150291A1 (en) 2015-10-30
RS54569B1 (en) 2016-06-30
MXPA06002644A (es) 2006-06-06
KR100883216B1 (ko) 2009-02-13
JP2014177500A (ja) 2014-09-25
US8173801B2 (en) 2012-05-08
JP2011046738A (ja) 2011-03-10
CA2538546A1 (en) 2005-05-19
US7915275B2 (en) 2011-03-29
ATE361927T1 (de) 2007-06-15
IL174271A (en) 2010-12-30
DE602004019298D1 (de) 2009-03-19
US20050101598A1 (en) 2005-05-12
WO2005044823A2 (en) 2005-05-19
BRPI0402382A (pt) 2005-06-28
RS54568B1 (en) 2016-06-30
US20080132530A1 (en) 2008-06-05
HRP20060093B1 (hr) 2015-12-18
DK1557421T3 (da) 2007-09-17
US20110160449A1 (en) 2011-06-30
JP5635376B2 (ja) 2014-12-03
SI1676847T1 (sl) 2009-06-30
ME00424B (me) 2011-10-10
RS20150292A1 (en) 2015-10-30
AU2004287601B8 (en) 2009-03-05
PL1676848T3 (pl) 2009-07-31
WO2005044823A3 (en) 2005-10-27
IL174271A0 (en) 2006-08-01
KR100855084B1 (ko) 2008-08-29
EP1557421B1 (en) 2007-05-09
ATE421965T1 (de) 2009-02-15
CO5560083A1 (es) 2005-09-30
BRPI0407149A (pt) 2006-02-07
NZ531622A (en) 2004-10-29
PL1557421T3 (pl) 2007-08-31
TW200515913A (en) 2005-05-16
RS54571B1 (en) 2016-06-30
DE602004006367C5 (de) 2019-04-04
CN101260114A (zh) 2008-09-10
JO2470B1 (en) 2009-01-20
UA86384C2 (uk) 2009-04-27
CN101260115B (zh) 2011-11-23
CN101260114B (zh) 2012-11-28
PT1676848E (pt) 2009-04-09
ZA200401948B (en) 2004-04-29
ES2244364T3 (es) 2007-12-01
PT1557421E (pt) 2007-07-31
SI1557421T1 (sl) 2007-08-31
TNSN06069A1 (en) 2007-10-03
DE602004006367T2 (de) 2007-09-06
KR100867751B1 (ko) 2008-11-10
DK1676848T3 (da) 2009-05-11
ITMI20032144A1 (it) 2005-05-08
AU2004287601B2 (en) 2009-02-26
KR20070113326A (ko) 2007-11-28

Similar Documents

Publication Publication Date Title
IL160798A0 (en) Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations
ZA200707397B (en) New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations
IL173204A0 (en) Novel cyanopyrrolidides, methods for the production thereof, and use of the same as medicaments
PL372931A1 (en) Novel thiophenylglycoside derivatives, methods for production thereof, medicaments comprising said compounds and use thereof
PL378065A1 (pl) Podstawione związki N-aryloheterocykliczne, sposób ich wytwarzania oraz ich zastosowanie jako środków leczniczych
IL191790B (en) The history of xanthine, their production and their use as medicines
HK1089768A1 (en) Indolone-acetamide derivatives, processes for preparing them and their uses
IL171170A (en) History of itensinoids and their pharmaceutical preparations, methods of preparation and use thereof
ZA200604432B (en) Thiozolidinones production and use thereof as medicaments
IL169818A0 (en) Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them
HK1082744A1 (en) Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof
HK1098737A1 (en) Process for the preparation of 1,1,1,3,3-pentafluoro-2-chloropropene and 1,1,1,3,3,3-hexafluoro-2-chloropropane
EP1731139A4 (en) PHARMACEUTICAL PREPARATION OF THE S / O TYPE AND MANUFACTURING METHOD THEREFOR
EP1820798A4 (en) 7-CYCLE CYCLIC COMPOUND, PROCESS FOR PRODUCTION AND MEDICINAL USE THEREOF
GB2426704B (en) Herbal oro-dental care composition and process for preparing the same
PL377741A1 (pl) Pochodne diarylocykloalkilowe, sposób ich wytwarzania i ich zastosowanie jako środka leczniczego
AU2003255612A8 (en) Novel multimeric molecules, the preparation method thereof and use of same for the preparation of medicaments
HK1100424A1 (en) Oral preparations and process for production thereof
PL1502590T3 (pl) Pochodne oksymów heterocyklicznych, ich sposób wytwarzania i ich zastosowanie w leczeniu cukrzycy typu II
TWI340745B (en) Novel diketopiperazine derivatives and the processes for preparation thereof
TWI318211B (en) Novel derivatives of 4a, 5, 9, 10, 11, 12-hexahydrobenzofuro [3a, 2, 2] [2] -benzazepine, method for the production thereof and use thereof in the production of medicaments
IL174975A0 (en) 2-phenyl-benzofuran derivatives, method for the production thereof and their use
EP1482937A4 (en) NOVEL TYLOINDICINS AND COMPOUNDS THEREFOR, PHARMACEUTICAL COMPOSITIONS AND METHODS
EP1648918A4 (en) NONGLYCOSYLATED HUMAN ALPHA-FETOPROTEIN, METHOD OF MANUFACTURE AND APPLICATIONS THEREOF
IL164248A0 (en) Acyl-3-carboxyphenylurea derivatives, processes for preparing them and their use