IL155842A0 - Diaryl peptides as ns3-serine protease inhibitors of hepatitis c virus - Google Patents

Diaryl peptides as ns3-serine protease inhibitors of hepatitis c virus

Info

Publication number
IL155842A0
IL155842A0 IL15584201A IL15584201A IL155842A0 IL 155842 A0 IL155842 A0 IL 155842A0 IL 15584201 A IL15584201 A IL 15584201A IL 15584201 A IL15584201 A IL 15584201A IL 155842 A0 IL155842 A0 IL 155842A0
Authority
IL
Israel
Prior art keywords
hepatitis
virus
protease inhibitors
serine protease
diaryl peptides
Prior art date
Application number
IL15584201A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL155842A0 publication Critical patent/IL155842A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL15584201A 2000-12-12 2001-12-10 Diaryl peptides as ns3-serine protease inhibitors of hepatitis c virus IL155842A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25486900P 2000-12-12 2000-12-12
PCT/US2001/047383 WO2002048172A2 (fr) 2000-12-12 2001-12-10 Peptides diaryliques utilises comme inhibiteurs de ns3-serine protease du virus de l'hepatite c

Publications (1)

Publication Number Publication Date
IL155842A0 true IL155842A0 (en) 2003-12-23

Family

ID=22965900

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15584201A IL155842A0 (en) 2000-12-12 2001-12-10 Diaryl peptides as ns3-serine protease inhibitors of hepatitis c virus

Country Status (18)

Country Link
US (1) US6911428B2 (fr)
EP (1) EP1343807B1 (fr)
JP (1) JP4368581B2 (fr)
KR (1) KR20030091946A (fr)
CN (1) CN1301994C (fr)
AR (1) AR031905A1 (fr)
AT (1) ATE430166T1 (fr)
AU (2) AU3659102A (fr)
CA (1) CA2430458A1 (fr)
DE (1) DE60138567D1 (fr)
ES (1) ES2324594T3 (fr)
HK (1) HK1054394B (fr)
HU (1) HUP0303436A2 (fr)
IL (1) IL155842A0 (fr)
MX (1) MXPA03005219A (fr)
PE (1) PE20020691A1 (fr)
WO (1) WO2002048172A2 (fr)
ZA (1) ZA200304382B (fr)

Families Citing this family (168)

* Cited by examiner, † Cited by third party
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JP2004532812A (ja) 2004-10-28
US20020147139A1 (en) 2002-10-10
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CA2430458A1 (fr) 2002-06-20
CN1301994C (zh) 2007-02-28
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AU3659102A (en) 2002-06-24
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US6911428B2 (en) 2005-06-28
AU2002236591B2 (en) 2005-07-14
ATE430166T1 (de) 2009-05-15
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