IL152900A0 - Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses - Google Patents
Water-soluble bacteriochlorophyll derivatives and their pharmaceutical usesInfo
- Publication number
- IL152900A0 IL152900A0 IL15290002A IL15290002A IL152900A0 IL 152900 A0 IL152900 A0 IL 152900A0 IL 15290002 A IL15290002 A IL 15290002A IL 15290002 A IL15290002 A IL 15290002A IL 152900 A0 IL152900 A0 IL 152900A0
- Authority
- IL
- Israel
- Prior art keywords
- water
- pharmaceutical uses
- bacteriochlorophyll derivatives
- soluble
- soluble bacteriochlorophyll
- Prior art date
Links
- DSJXIQQMORJERS-AGGZHOMASA-M bacteriochlorophyll a Chemical class C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC([C@H](CC)[C@H]3C)=[N+]4C3=CC3=C(C(C)=O)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 DSJXIQQMORJERS-AGGZHOMASA-M 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0036—Porphyrins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0624—Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/08—Copper compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/006—Palladium compounds
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/006—Palladium compounds
- C07F15/0066—Palladium compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/04—Nickel compounds
- C07F15/045—Nickel compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/02—Magnesium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/06—Zinc compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Priority Applications (36)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL15290002A IL152900A0 (en) | 2002-11-17 | 2002-11-17 | Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses |
JP2004553058A JP4922559B2 (ja) | 2002-11-17 | 2003-11-17 | 水溶性陰イオン性バクテリオクロロフィル誘導体及びそれらの使用 |
RU2005118771/13A RU2353624C2 (ru) | 2002-11-17 | 2003-11-17 | Водорастворимые анионсодержащие производные бактериохлорофилла и их применение |
EP03773967.9A EP1567147B1 (de) | 2002-11-17 | 2003-11-17 | Wasserlösliche anionische bakteriochlorophyll-derivate und ihre verwendungen |
CA2506296A CA2506296C (en) | 2002-11-17 | 2003-11-17 | Water-soluble anionic bacteriochlorophyll derivatives and their uses |
PL376734A PL216661B1 (pl) | 2002-11-17 | 2003-11-17 | Rozpuszczalne w wodzie anionowe pochodne bakteriochlorofilu, sposób ich wytwarzania, kompozycja farmaceutyczna zawierająca te pochodne oraz ich zastosowanie |
NZ540790A NZ540790A (en) | 2002-11-17 | 2003-11-17 | Water-soluble tetracyclic and pentacyclic anionic bacteriochlorophyll derivatives and their uses |
ES03773967.9T ES2489516T3 (es) | 2002-11-17 | 2003-11-17 | Derivados bacterioclorofílicos aniónicos solubles en agua y sus utilizaciones |
CN2003801089065A CN1741801B (zh) | 2002-11-17 | 2003-11-17 | 水溶性阴离子型细菌叶绿素衍生物及其用途 |
CN2010105268579A CN102002048B (zh) | 2002-11-17 | 2003-11-17 | 水溶性阴离子型细菌叶绿素衍生物及其用途 |
US10/534,692 US7947672B2 (en) | 2002-11-17 | 2003-11-17 | Water-soluble anionic bacteriochlorophyll derivatives and their uses |
BRPI0316319A BRPI0316319B8 (pt) | 2002-11-17 | 2003-11-17 | derivados de bacterioclorofila aniônicos solúveis em água, composição farmacêutica, usos dos derivados e método para preparo dos mesmos |
PCT/IL2003/000973 WO2004045492A2 (en) | 2002-11-17 | 2003-11-17 | Water-soluble anionic bacteriochlorophyll derivatives and their uses |
DK03773967.9T DK1567147T3 (da) | 2002-11-17 | 2003-11-17 | Vandopløselige anioniske bakteriochlorofylderivater og deres anvendelser |
PT37739679T PT1567147E (pt) | 2002-11-17 | 2003-11-17 | Derivados de bacterioclorofila aniónicos solúveis em água e as suas utilizações |
MXPA05005262A MXPA05005262A (es) | 2002-11-17 | 2003-11-17 | Derivados anionicos de bacterioclorofila solubles en agua y sus usos. |
AU2003282354A AU2003282354C1 (en) | 2002-11-17 | 2003-11-17 | Water-soluble anionic bacteriochlorophyll derivatives and their uses |
EP20120161201 EP2522349A1 (de) | 2002-11-17 | 2003-11-17 | Wasserlösliche anionische Bakteriochlorophyl-Derivate und ihre Verwendungen |
IL168480A IL168480A (en) | 2002-11-17 | 2005-05-09 | History of water-soluble anhydrous bacteriochlorophyll, pharmaceuticals containing them, their use for photodynamic therapy and tumor diagnosis, and methods for preparing them |
NO20052925A NO334978B1 (no) | 2002-11-17 | 2005-06-15 | Vannløselig anionisk bakterieklorofyllderivat, fremgangsmåte for fremstilling derav, farmasøytisk sammensetning som inneholder nevnte derivat og anvendelse derav. |
HK06102165.9A HK1081858A1 (en) | 2002-11-17 | 2006-02-17 | Water-soluble anionic bacteriochlorophyll derivatives and their uses |
US12/942,938 US8461142B2 (en) | 2002-11-17 | 2010-11-09 | Water-soluble anionic bacteriochlorophyll derivatives and their uses |
JP2011096875A JP5566945B2 (ja) | 2002-11-17 | 2011-04-25 | 水溶性陰イオン性バクテリオクロロフィル誘導体及びそれらの使用 |
JP2011096876A JP5555659B2 (ja) | 2002-11-17 | 2011-04-25 | 水溶性陰イオン性バクテリオクロロフィル誘導体及びそれらの使用 |
US13/890,126 US20130345417A1 (en) | 2002-11-17 | 2013-05-08 | Water soluble anionic bacteriochlorophyll derivatives and their uses |
CY20141100619T CY1115458T1 (el) | 2002-11-17 | 2014-08-07 | Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων |
US14/504,347 US20150238773A1 (en) | 2002-11-17 | 2014-10-01 | Water soluble anionic bacteriochlorophyll derivatives and their uses |
US15/425,473 US20170143988A1 (en) | 2002-11-17 | 2017-02-06 | Water soluble anionic bacteriochlorophyll derivatives and their uses |
NO2018012C NO2018012I2 (no) | 2002-11-17 | 2018-04-10 | Padeliporfin |
LU00073C LUC00073I2 (en) | 2002-11-17 | 2018-04-11 | Water-soluble anionic bacteriochlorophyll derivatives and their uses |
FR18C0002C FR18C0002I2 (fr) | 2002-11-17 | 2018-04-17 | Derives bacteriochlorophylles anioniques solubles dans l'eau et leurs utilisations |
HUS1800020C HUS1800020I1 (hu) | 2002-11-17 | 2018-04-25 | Vízben oldódó anionos bakterioklorofill származékok és azok alkalmazásai |
NL300934C NL300934I2 (nl) | 2002-11-17 | 2018-04-26 | Padeliporfine (als di-kalium zout) |
BE2018C018C BE2018C018I2 (de) | 2002-11-17 | 2018-05-02 | |
CY2018012C CY2018012I1 (el) | 2002-11-17 | 2018-05-04 | Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων |
US16/397,515 US20200094069A1 (en) | 2002-11-17 | 2019-04-29 | Water soluble anionic bacteriochlorophyll derivatives and their uses |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL15290002A IL152900A0 (en) | 2002-11-17 | 2002-11-17 | Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses |
Publications (1)
Publication Number | Publication Date |
---|---|
IL152900A0 true IL152900A0 (en) | 2003-06-24 |
Family
ID=30011928
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15290002A IL152900A0 (en) | 2002-11-17 | 2002-11-17 | Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses |
IL168480A IL168480A (en) | 2002-11-17 | 2005-05-09 | History of water-soluble anhydrous bacteriochlorophyll, pharmaceuticals containing them, their use for photodynamic therapy and tumor diagnosis, and methods for preparing them |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL168480A IL168480A (en) | 2002-11-17 | 2005-05-09 | History of water-soluble anhydrous bacteriochlorophyll, pharmaceuticals containing them, their use for photodynamic therapy and tumor diagnosis, and methods for preparing them |
Country Status (24)
Country | Link |
---|---|
US (6) | US7947672B2 (de) |
EP (2) | EP2522349A1 (de) |
JP (3) | JP4922559B2 (de) |
CN (2) | CN102002048B (de) |
AU (1) | AU2003282354C1 (de) |
BE (1) | BE2018C018I2 (de) |
BR (1) | BRPI0316319B8 (de) |
CA (1) | CA2506296C (de) |
CY (2) | CY1115458T1 (de) |
DK (1) | DK1567147T3 (de) |
ES (1) | ES2489516T3 (de) |
FR (1) | FR18C0002I2 (de) |
HK (1) | HK1081858A1 (de) |
HU (1) | HUS1800020I1 (de) |
IL (2) | IL152900A0 (de) |
LU (1) | LUC00073I2 (de) |
MX (1) | MXPA05005262A (de) |
NL (1) | NL300934I2 (de) |
NO (2) | NO334978B1 (de) |
NZ (1) | NZ540790A (de) |
PL (1) | PL216661B1 (de) |
PT (1) | PT1567147E (de) |
RU (1) | RU2353624C2 (de) |
WO (1) | WO2004045492A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL152900A0 (en) * | 2002-11-17 | 2003-06-24 | Yeda Res & Dev | Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses |
CN1980661B (zh) * | 2004-06-07 | 2011-09-28 | 耶达研究及发展有限公司 | 阳离子细菌叶绿素衍生物及其用途 |
US9957293B2 (en) * | 2006-08-23 | 2018-05-01 | Yeda Research And Development Company Ltd. | Conjugates of RGD peptides and porphyrin or (bacterio)chlorophyll photosynthesizers and their uses |
AU2009219682B2 (en) | 2008-02-27 | 2015-06-18 | Yeda Research & Development Co. Ltd | RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and imaging of necrotic tumors |
EP2425873A1 (de) | 2010-09-07 | 2012-03-07 | Steba Maor SA | Modellierung der Wirkung einer Glasfaser in einer Behandlung durch photodynamische Therapie, und Unterstützung der Planung einer solchen Behandlung |
BR112013023162A2 (pt) | 2011-03-11 | 2017-07-25 | Abenhaim Lucien | métodos de terapia fotodinâmica focal |
JP6215203B2 (ja) * | 2011-08-23 | 2017-10-18 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッドYeda Research And Development Co. Ltd | 眼疾患および障害の治療用の(バクテリオ)クロロフィル光増感剤 |
PL2971026T3 (pl) | 2013-03-11 | 2021-06-14 | Tookad Ip Sarl | Sposób wytwarzania bakteriochlorofilu a |
CA2907356C (en) | 2013-03-15 | 2022-07-12 | Sherri Ann MCFARLAND | Metal-based coordination complexes as photodynamic compounds and their use |
KR20220139445A (ko) * | 2016-04-10 | 2022-10-14 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 암 치료를 위한 병용 요법 |
CN107987081B (zh) * | 2016-10-26 | 2019-12-06 | 刘辉 | 一种二氢卟吩e6衍生物及其药学上可接受的盐、其制备方法和应用 |
RS65011B1 (sr) * | 2016-12-22 | 2024-01-31 | Daiichi Sankyo Co Ltd | Peptid za lečenje makularne degeneracije povezane sa starenjem |
US10933134B2 (en) | 2017-03-16 | 2021-03-02 | Memorial Sloan Kettering Cancer Center | Combination therapies for treatment of cancer |
EP3723785A1 (de) * | 2017-12-17 | 2020-10-21 | Yeda Research and Development Co. Ltd | Komplexe modulatoren des cop9-signalosoms (csn) und deren verwendung |
CN111848656B (zh) * | 2020-06-24 | 2023-03-14 | 天津大学 | 离子修饰的原卟啉镓化合物及其制备方法和应用 |
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