CY2018012I2 - Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων - Google Patents

Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων

Info

Publication number
CY2018012I2
CY2018012I2 CY2018012C CY2018012C CY2018012I2 CY 2018012 I2 CY2018012 I2 CY 2018012I2 CY 2018012 C CY2018012 C CY 2018012C CY 2018012 C CY2018012 C CY 2018012C CY 2018012 I2 CY2018012 I2 CY 2018012I2
Authority
CY
Cyprus
Prior art keywords
bacteriochlorophylla
water
soluble anionic
anionic derivatives
derivatives
Prior art date
Application number
CY2018012C
Other languages
English (en)
Other versions
CY2018012I1 (el
Original Assignee
Yeda Research And Development Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30011928&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2018012(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yeda Research And Development Co., Ltd. filed Critical Yeda Research And Development Co., Ltd.
Publication of CY2018012I2 publication Critical patent/CY2018012I2/el
Publication of CY2018012I1 publication Critical patent/CY2018012I1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0624—Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic System
    • C07F1/08—Copper compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/006—Palladium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/006—Palladium compounds
    • C07F15/0066—Palladium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/04—Nickel compounds
    • C07F15/045—Nickel compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/02—Magnesium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/06—Zinc compounds
CY2018012C 2002-11-17 2018-05-04 Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων CY2018012I1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15290002A IL152900A0 (en) 2002-11-17 2002-11-17 Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
PCT/IL2003/000973 WO2004045492A2 (en) 2002-11-17 2003-11-17 Water-soluble anionic bacteriochlorophyll derivatives and their uses

Publications (2)

Publication Number Publication Date
CY2018012I2 true CY2018012I2 (el) 2018-09-05
CY2018012I1 CY2018012I1 (el) 2018-09-05

Family

ID=30011928

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20141100619T CY1115458T1 (el) 2002-11-17 2014-08-07 Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων
CY2018012C CY2018012I1 (el) 2002-11-17 2018-05-04 Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20141100619T CY1115458T1 (el) 2002-11-17 2014-08-07 Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων

Country Status (24)

Country Link
US (6) US7947672B2 (el)
EP (2) EP1567147B1 (el)
JP (3) JP4922559B2 (el)
CN (2) CN102002048B (el)
AU (1) AU2003282354C1 (el)
BE (1) BE2018C018I2 (el)
BR (1) BRPI0316319B8 (el)
CA (1) CA2506296C (el)
CY (2) CY1115458T1 (el)
DK (1) DK1567147T3 (el)
ES (1) ES2489516T3 (el)
FR (1) FR18C0002I2 (el)
HK (1) HK1081858A1 (el)
HU (1) HUS1800020I1 (el)
IL (2) IL152900A0 (el)
LU (1) LUC00073I2 (el)
MX (1) MXPA05005262A (el)
NL (1) NL300934I2 (el)
NO (2) NO334978B1 (el)
NZ (1) NZ540790A (el)
PL (1) PL216661B1 (el)
PT (1) PT1567147E (el)
RU (1) RU2353624C2 (el)
WO (1) WO2004045492A2 (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
HUE030586T2 (en) 2004-06-07 2017-06-28 Yeda Res & Dev Cationic bacteriochlorophyll derivatives and their uses
US9957293B2 (en) * 2006-08-23 2018-05-01 Yeda Research And Development Company Ltd. Conjugates of RGD peptides and porphyrin or (bacterio)chlorophyll photosynthesizers and their uses
EP2257309B1 (en) 2008-02-27 2019-10-16 Yeda Research And Development Company Ltd. Rgd-(bacterio)chlorophyll conjugates for use in diagnosis of tumors comprising necrotic domains
EP2425873A1 (fr) 2010-09-07 2012-03-07 Steba Maor SA Modélisation de l'action d'une fibre optique dans un traitement par therapie photodynamique, et assistance à la planification d'un tel traitement
BR112013023162A2 (pt) 2011-03-11 2017-07-25 Abenhaim Lucien métodos de terapia fotodinâmica focal
PT2747763T (pt) 2011-08-23 2021-02-22 Yeda Res & Dev Fotossensibilizadores de (bacterio)clorofila para o tratamento de doenças e distúrbios oculares
EP2971026B1 (en) 2013-03-11 2020-11-18 Tookad Ip Sarl Method for producing bacteriochlorophyll a
CA2907356C (en) 2013-03-15 2022-07-12 Sherri Ann MCFARLAND Metal-based coordination complexes as photodynamic compounds and their use
RU2021110230A (ru) * 2016-04-10 2021-05-26 Йеда Рисерч Энд Дивелопмент Ко. Лтд. Комбинированные способы терапии для лечения злокачественной опухоли
CN107987081B (zh) * 2016-10-26 2019-12-06 刘辉 一种二氢卟吩e6衍生物及其药学上可接受的盐、其制备方法和应用
AU2017384348B2 (en) * 2016-12-22 2024-03-07 Daiichi Sankyo Company, Limited Peptide for treating age-related macular degeneration
US10933134B2 (en) 2017-03-16 2021-03-02 Memorial Sloan Kettering Cancer Center Combination therapies for treatment of cancer
WO2019116376A1 (en) * 2017-12-17 2019-06-20 Yeda Research And Development Co. Ltd. Cop9 signalosome (csn) complex modulators and uses thereof
CN111848656B (zh) * 2020-06-24 2023-03-14 天津大学 离子修饰的原卟啉镓化合物及其制备方法和应用
CN116033913A (zh) * 2020-07-29 2023-04-28 国立大学法人北陆先端科学技术大学院大学 癌症的治疗药或诊断药
CN115843960A (zh) * 2022-11-03 2023-03-28 中国农业科学院农产品加工研究所 一种提高叶绿素稳定性的方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4512762A (en) 1982-11-23 1985-04-23 The Beth Israel Hospital Association Method of treatment of atherosclerosis and a balloon catheter for same
US4693885A (en) * 1984-07-18 1987-09-15 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4675338A (en) * 1984-07-18 1987-06-23 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4977177A (en) * 1985-04-30 1990-12-11 Nippon Petrochemicals Company, Ltd. Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents
US4656186A (en) * 1985-04-30 1987-04-07 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
JPS63196586A (ja) * 1987-02-12 1988-08-15 Toyo Hatsuka Kogyo Kk バクテリオフエオホ−バイド誘導体
DE3853995T2 (de) * 1987-04-17 1995-11-23 David H Dolphin Porphyrine, verfahren zu deren herstellung und verwendungen.
US5004811A (en) 1987-12-24 1991-04-02 Nippon Petrochemicals Company, Ltd. Tetrapyrrole aminocarboxylic acids
US5171741A (en) * 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
DE4121876A1 (de) * 1991-07-02 1993-01-14 Scheer Hugo Modifizierte bakteriochlorophylle, verfahren zu ihrer herstellung und ihre verwendung
JP3191223B2 (ja) * 1991-10-04 2001-07-23 株式会社光ケミカル研究所 ポルフィリン誘導体とその用途
JPH08506566A (ja) * 1992-06-19 1996-07-16 ザ・ユニバーシティ・オブ・トリド ポルフィリン系イミンの製造方法及び使用方法
IL102645A (en) * 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
US6147195A (en) * 1993-07-26 2000-11-14 Yeda Research And Development Co., Ltd. Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
FR2712493B1 (fr) * 1993-11-16 1996-01-19 Centre Nat Rech Scient Utilisation de photosensibilisateurs dérivés du noyau phorbine pour la décontamination du sang infecté par des parasites et/ou des virus.
JPH09110872A (ja) 1995-10-23 1997-04-28 Eiken Chem Co Ltd ヨードポルフィリン誘導体
IL116126A0 (en) 1995-11-24 1996-01-31 Yeda Res & Dev Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them
GB9524553D0 (en) * 1995-11-30 1996-01-31 Britton Charles J Plastic lever lid tins
US5770730A (en) * 1996-03-08 1998-06-23 Health Research, Inc. Synthesis of carbodimide analogs of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer
US6063777A (en) * 1996-10-01 2000-05-16 Wyeth Lederle Japan, Ltd. Iminochlorinaspartic acid derivatives
IL129929A0 (en) * 1996-12-17 2000-02-29 Du Pont Polymerization of ethylene with specific iron or cobalt complexes novel pyridinebis (imines) and novel complexes of pyridinebis(imines) with iron and cobalt
DE69934328T2 (de) * 1998-12-09 2007-07-19 Yeda Research And Development Co., Ltd. Palladiumsubstituierte bakteriochlorophyllderivate und deren verwendung
IL133253A0 (en) 1999-12-01 2001-04-30 Yeda Res & Dev Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
JP4277159B2 (ja) 2000-06-02 2009-06-10 独立行政法人科学技術振興機構 新規なテトラピロリル置換ポルフィリン及びその製法
WO2002013820A1 (en) 2000-08-11 2002-02-21 Ceramoptec Industries, Inc. Photosensitizing ointment
WO2002098882A1 (en) 2001-06-01 2002-12-12 Ceramoptec Industries, Inc. Water-soluble porphyrin derivatives for photodynamic therapy, their use and manufacture
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses

Also Published As

Publication number Publication date
EP1567147B1 (en) 2014-05-07
CN1741801B (zh) 2010-12-22
FR18C0002I1 (el) 2018-06-15
US7947672B2 (en) 2011-05-24
DK1567147T3 (da) 2014-08-11
US20110117029A1 (en) 2011-05-19
AU2003282354A1 (en) 2004-06-15
US20170143988A1 (en) 2017-05-25
BRPI0316319B8 (pt) 2021-05-25
CA2506296A1 (en) 2004-06-03
HK1081858A1 (en) 2006-05-26
BE2018C018I2 (el) 2023-03-07
CN1741801A (zh) 2006-03-01
US20200094069A1 (en) 2020-03-26
US20130345417A1 (en) 2013-12-26
IL168480A (en) 2015-01-29
US8461142B2 (en) 2013-06-11
RU2353624C2 (ru) 2009-04-27
JP2011162551A (ja) 2011-08-25
PL216661B1 (pl) 2014-04-30
ES2489516T3 (es) 2014-09-02
NO2018012I1 (no) 2018-04-10
LUC00073I2 (en) 2018-06-20
CY2018012I1 (el) 2018-09-05
CA2506296C (en) 2012-09-11
IL152900A0 (en) 2003-06-24
US20060142260A1 (en) 2006-06-29
CY1115458T1 (el) 2017-01-04
NZ540790A (en) 2009-12-24
NO334978B1 (no) 2014-08-11
AU2003282354C1 (en) 2009-10-29
PL376734A1 (pl) 2006-01-09
NO20052925L (no) 2005-06-15
JP2011148822A (ja) 2011-08-04
WO2004045492A2 (en) 2004-06-03
MXPA05005262A (es) 2005-07-25
US20150238773A1 (en) 2015-08-27
JP5555659B2 (ja) 2014-07-23
NO20052925D0 (no) 2005-06-15
JP2006515836A (ja) 2006-06-08
PT1567147E (pt) 2014-08-25
JP5566945B2 (ja) 2014-08-06
WO2004045492A3 (en) 2004-07-08
AU2003282354B2 (en) 2009-04-23
RU2005118771A (ru) 2006-01-20
BR0316319A (pt) 2005-09-27
AU2003282354B8 (en) 2009-05-14
NO2018012I2 (no) 2018-04-10
FR18C0002I2 (fr) 2020-03-13
BRPI0316319B1 (pt) 2017-06-27
CN102002048A (zh) 2011-04-06
EP2522349A1 (en) 2012-11-14
CN102002048B (zh) 2012-11-28
HUS1800020I1 (hu) 2018-05-28
JP4922559B2 (ja) 2012-04-25
EP1567147A4 (en) 2008-07-09
NL300934I2 (nl) 2018-05-22
EP1567147A2 (en) 2005-08-31

Similar Documents

Publication Publication Date Title
CY2018012I1 (el) Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων
CY2018009I2 (el) Παραλλαγες ανοσοσφαιρινων και χρησεις αυτων
CY2014033I1 (el) Παραγωγα κινολινης και η χρηση τους ως μυκοβακτηριακων αναστολεων
IS2504B (is) Fosfónóoxýkínasólínafleiður og lyfjafræileg notkun þeirra
CY2014001I1 (el) Συνδυασμος αζελαστινης και φλουτικαζονης
DE602004032276D1 (de) Tetrahydro-Naphthalen und Harnstoffderivate
CY2013043I1 (el) Ενωσεις 4-οξοκινολινης και χρησιμοποιηση αυτων ως αναστολεις της ενσωματασης του hiv
NO20041272L (no) Tetracycline derivatives and methods of use thereof
CY2015018I2 (el) Ανθρωπινα αντισωματα ειδικα για kdr και χρησεις αυτων
CY2012025I1 (el) Υπο-ακετυλιωμενα και υπερ-ακετυλιωμενα μηνιγγοκοκκικα καψικα σακχαριδια
DE60239403D1 (de) Elektromechanischer mikrosensor
EE200500011A (et) Indasoolid, bensotiasoolid ja bensoisotiasoolid, nende valmistamine ning kasutamine
ATE390426T1 (de) Aminocyclische substituierte pyrrolopyrimidinderivate und pyrrolopyridinderivate
DE60334292D1 (de) Ylenverbundemulsionszusammensetzung und verwendung davon
DE60330269D1 (de) Piperazinyl- und diazapanylbenzamide und-benzothioamide
DE60311467D1 (de) Dispersion von wasserlöslichem polymer, herstellungsverfahren dafür und verwendungsverfahren dafür
DE60317772D1 (de) Zweirichtungenmischrotor und verfahren
ATE489069T1 (de) Mundpflegezusammensetzungen und -verfahren
DE60224452D1 (de) Haarfärbeverfahren und haarfärbesatz
FI20010075A (fi) Terveysvaikutteinen tuote ja menetelmä
DE60336720D1 (de) Fluorsulfate von hexafluorisobutylen und dessen höheren homologen und deren derivaten
AU2003252696A1 (en) Water-soluble keratin derivative and use thereof
DE60321641D1 (de) Photopolymerisierbare Initiatorkombination und photopolymerisierbare Zusammensetzung
ATE299873T1 (de) Substituierte c-furan-2-yl-methylamin- und c- thiophen-2-yl-methylamin-derivate
EE200300454A (et) Bitsüklilised guanidiini derivaadid ja nende terapeutiline kasutamine