IL152900A0 - Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses - Google Patents

Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses

Info

Publication number
IL152900A0
IL152900A0 IL15290002A IL15290002A IL152900A0 IL 152900 A0 IL152900 A0 IL 152900A0 IL 15290002 A IL15290002 A IL 15290002A IL 15290002 A IL15290002 A IL 15290002A IL 152900 A0 IL152900 A0 IL 152900A0
Authority
IL
Israel
Prior art keywords
water
pharmaceutical uses
bacteriochlorophyll derivatives
soluble
soluble bacteriochlorophyll
Prior art date
Application number
IL15290002A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30011928&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL152900(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL15290002A priority Critical patent/IL152900A0/xx
Publication of IL152900A0 publication Critical patent/IL152900A0/xx
Priority to PCT/IL2003/000973 priority patent/WO2004045492A2/en
Priority to JP2004553058A priority patent/JP4922559B2/ja
Priority to EP03773967.9A priority patent/EP1567147B1/en
Priority to PT37739679T priority patent/PT1567147E/pt
Priority to NZ540790A priority patent/NZ540790A/en
Priority to CN2010105268579A priority patent/CN102002048B/zh
Priority to CA2506296A priority patent/CA2506296C/en
Priority to ES03773967.9T priority patent/ES2489516T3/es
Priority to AU2003282354A priority patent/AU2003282354C1/en
Priority to RU2005118771/13A priority patent/RU2353624C2/ru
Priority to BRPI0316319A priority patent/BRPI0316319B8/pt
Priority to DK03773967.9T priority patent/DK1567147T3/da
Priority to US10/534,692 priority patent/US7947672B2/en
Priority to MXPA05005262A priority patent/MXPA05005262A/es
Priority to PL376734A priority patent/PL216661B1/pl
Priority to CN2003801089065A priority patent/CN1741801B/zh
Priority to EP20120161201 priority patent/EP2522349A1/en
Priority to IL168480A priority patent/IL168480A/en
Priority to NO20052925A priority patent/NO334978B1/no
Priority to HK06102165.9A priority patent/HK1081858A1/xx
Priority to US12/942,938 priority patent/US8461142B2/en
Priority to JP2011096875A priority patent/JP5566945B2/ja
Priority to JP2011096876A priority patent/JP5555659B2/ja
Priority to US13/890,126 priority patent/US20130345417A1/en
Priority to CY20141100619T priority patent/CY1115458T1/el
Priority to US14/504,347 priority patent/US20150238773A1/en
Priority to US15/425,473 priority patent/US20170143988A1/en
Priority to NO2018012C priority patent/NO2018012I2/no
Priority to LU00073C priority patent/LUC00073I2/fr
Priority to FR18C0002C priority patent/FR18C0002I2/fr
Priority to HUS1800020C priority patent/HUS1800020I1/hu
Priority to NL300934C priority patent/NL300934I2/nl
Priority to BE2018C018C priority patent/BE2018C018I2/nl
Priority to CY2018012C priority patent/CY2018012I1/el
Priority to US16/397,515 priority patent/US20200094069A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0624—Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic System
    • C07F1/08—Copper compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/006—Palladium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/006—Palladium compounds
    • C07F15/0066—Palladium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/04—Nickel compounds
    • C07F15/045—Nickel compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/02—Magnesium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/06—Zinc compounds
IL15290002A 2002-11-17 2002-11-17 Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses IL152900A0 (en)

Priority Applications (36)

Application Number Priority Date Filing Date Title
IL15290002A IL152900A0 (en) 2002-11-17 2002-11-17 Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
CN2003801089065A CN1741801B (zh) 2002-11-17 2003-11-17 水溶性阴离子型细菌叶绿素衍生物及其用途
RU2005118771/13A RU2353624C2 (ru) 2002-11-17 2003-11-17 Водорастворимые анионсодержащие производные бактериохлорофилла и их применение
PL376734A PL216661B1 (pl) 2002-11-17 2003-11-17 Rozpuszczalne w wodzie anionowe pochodne bakteriochlorofilu, sposób ich wytwarzania, kompozycja farmaceutyczna zawierająca te pochodne oraz ich zastosowanie
EP20120161201 EP2522349A1 (en) 2002-11-17 2003-11-17 Water-Soluble Anionic Bacteriochlorophyll Derivatives and their Uses
EP03773967.9A EP1567147B1 (en) 2002-11-17 2003-11-17 Water-soluble anionic bacteriochlorophyll derivatives and their uses
PT37739679T PT1567147E (pt) 2002-11-17 2003-11-17 Derivados de bacterioclorofila aniónicos solúveis em água e as suas utilizações
NZ540790A NZ540790A (en) 2002-11-17 2003-11-17 Water-soluble tetracyclic and pentacyclic anionic bacteriochlorophyll derivatives and their uses
CN2010105268579A CN102002048B (zh) 2002-11-17 2003-11-17 水溶性阴离子型细菌叶绿素衍生物及其用途
CA2506296A CA2506296C (en) 2002-11-17 2003-11-17 Water-soluble anionic bacteriochlorophyll derivatives and their uses
ES03773967.9T ES2489516T3 (es) 2002-11-17 2003-11-17 Derivados bacterioclorofílicos aniónicos solubles en agua y sus utilizaciones
AU2003282354A AU2003282354C1 (en) 2002-11-17 2003-11-17 Water-soluble anionic bacteriochlorophyll derivatives and their uses
JP2004553058A JP4922559B2 (ja) 2002-11-17 2003-11-17 水溶性陰イオン性バクテリオクロロフィル誘導体及びそれらの使用
BRPI0316319A BRPI0316319B8 (pt) 2002-11-17 2003-11-17 derivados de bacterioclorofila aniônicos solúveis em água, composição farmacêutica, usos dos derivados e método para preparo dos mesmos
DK03773967.9T DK1567147T3 (da) 2002-11-17 2003-11-17 Vandopløselige anioniske bakteriochlorofylderivater og deres anvendelser
US10/534,692 US7947672B2 (en) 2002-11-17 2003-11-17 Water-soluble anionic bacteriochlorophyll derivatives and their uses
MXPA05005262A MXPA05005262A (es) 2002-11-17 2003-11-17 Derivados anionicos de bacterioclorofila solubles en agua y sus usos.
PCT/IL2003/000973 WO2004045492A2 (en) 2002-11-17 2003-11-17 Water-soluble anionic bacteriochlorophyll derivatives and their uses
IL168480A IL168480A (en) 2002-11-17 2005-05-09 History of water-soluble anhydrous bacteriochlorophyll, pharmaceuticals containing them, their use for photodynamic therapy and tumor diagnosis, and methods for preparing them
NO20052925A NO334978B1 (no) 2002-11-17 2005-06-15 Vannløselig anionisk bakterieklorofyllderivat, fremgangsmåte for fremstilling derav, farmasøytisk sammensetning som inneholder nevnte derivat og anvendelse derav.
HK06102165.9A HK1081858A1 (en) 2002-11-17 2006-02-17 Water-soluble anionic bacteriochlorophyll derivatives and their uses
US12/942,938 US8461142B2 (en) 2002-11-17 2010-11-09 Water-soluble anionic bacteriochlorophyll derivatives and their uses
JP2011096875A JP5566945B2 (ja) 2002-11-17 2011-04-25 水溶性陰イオン性バクテリオクロロフィル誘導体及びそれらの使用
JP2011096876A JP5555659B2 (ja) 2002-11-17 2011-04-25 水溶性陰イオン性バクテリオクロロフィル誘導体及びそれらの使用
US13/890,126 US20130345417A1 (en) 2002-11-17 2013-05-08 Water soluble anionic bacteriochlorophyll derivatives and their uses
CY20141100619T CY1115458T1 (el) 2002-11-17 2014-08-07 Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων
US14/504,347 US20150238773A1 (en) 2002-11-17 2014-10-01 Water soluble anionic bacteriochlorophyll derivatives and their uses
US15/425,473 US20170143988A1 (en) 2002-11-17 2017-02-06 Water soluble anionic bacteriochlorophyll derivatives and their uses
NO2018012C NO2018012I2 (no) 2002-11-17 2018-04-10 Padeliporfin
LU00073C LUC00073I2 (en) 2002-11-17 2018-04-11 Water-soluble anionic bacteriochlorophyll derivatives and their uses
FR18C0002C FR18C0002I2 (fr) 2002-11-17 2018-04-17 Derives bacteriochlorophylles anioniques solubles dans l'eau et leurs utilisations
HUS1800020C HUS1800020I1 (hu) 2002-11-17 2018-04-25 Vízben oldódó anionos bakterioklorofill származékok és azok alkalmazásai
NL300934C NL300934I2 (nl) 2002-11-17 2018-04-26 Padeliporfine (als di-kalium zout)
BE2018C018C BE2018C018I2 (xx) 2002-11-17 2018-05-02
CY2018012C CY2018012I1 (el) 2002-11-17 2018-05-04 Υδατοδιαλυτα ανιοντικα παραγωγα βακτηριοχλωροφυλλης και η χρηση αυτων
US16/397,515 US20200094069A1 (en) 2002-11-17 2019-04-29 Water soluble anionic bacteriochlorophyll derivatives and their uses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL15290002A IL152900A0 (en) 2002-11-17 2002-11-17 Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses

Publications (1)

Publication Number Publication Date
IL152900A0 true IL152900A0 (en) 2003-06-24

Family

ID=30011928

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15290002A IL152900A0 (en) 2002-11-17 2002-11-17 Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
IL168480A IL168480A (en) 2002-11-17 2005-05-09 History of water-soluble anhydrous bacteriochlorophyll, pharmaceuticals containing them, their use for photodynamic therapy and tumor diagnosis, and methods for preparing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL168480A IL168480A (en) 2002-11-17 2005-05-09 History of water-soluble anhydrous bacteriochlorophyll, pharmaceuticals containing them, their use for photodynamic therapy and tumor diagnosis, and methods for preparing them

Country Status (24)

Country Link
US (6) US7947672B2 (xx)
EP (2) EP1567147B1 (xx)
JP (3) JP4922559B2 (xx)
CN (2) CN102002048B (xx)
AU (1) AU2003282354C1 (xx)
BE (1) BE2018C018I2 (xx)
BR (1) BRPI0316319B8 (xx)
CA (1) CA2506296C (xx)
CY (2) CY1115458T1 (xx)
DK (1) DK1567147T3 (xx)
ES (1) ES2489516T3 (xx)
FR (1) FR18C0002I2 (xx)
HK (1) HK1081858A1 (xx)
HU (1) HUS1800020I1 (xx)
IL (2) IL152900A0 (xx)
LU (1) LUC00073I2 (xx)
MX (1) MXPA05005262A (xx)
NL (1) NL300934I2 (xx)
NO (2) NO334978B1 (xx)
NZ (1) NZ540790A (xx)
PL (1) PL216661B1 (xx)
PT (1) PT1567147E (xx)
RU (1) RU2353624C2 (xx)
WO (1) WO2004045492A2 (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
HUE030586T2 (en) 2004-06-07 2017-06-28 Yeda Res & Dev Cationic bacteriochlorophyll derivatives and their uses
US9957293B2 (en) * 2006-08-23 2018-05-01 Yeda Research And Development Company Ltd. Conjugates of RGD peptides and porphyrin or (bacterio)chlorophyll photosynthesizers and their uses
EP2257309B1 (en) 2008-02-27 2019-10-16 Yeda Research And Development Company Ltd. Rgd-(bacterio)chlorophyll conjugates for use in diagnosis of tumors comprising necrotic domains
EP2425873A1 (fr) 2010-09-07 2012-03-07 Steba Maor SA Modélisation de l'action d'une fibre optique dans un traitement par therapie photodynamique, et assistance à la planification d'un tel traitement
BR112013023162A2 (pt) 2011-03-11 2017-07-25 Abenhaim Lucien métodos de terapia fotodinâmica focal
PT2747763T (pt) 2011-08-23 2021-02-22 Yeda Res & Dev Fotossensibilizadores de (bacterio)clorofila para o tratamento de doenças e distúrbios oculares
EP2971026B1 (en) 2013-03-11 2020-11-18 Tookad Ip Sarl Method for producing bacteriochlorophyll a
CA2907356C (en) 2013-03-15 2022-07-12 Sherri Ann MCFARLAND Metal-based coordination complexes as photodynamic compounds and their use
RU2021110230A (ru) * 2016-04-10 2021-05-26 Йеда Рисерч Энд Дивелопмент Ко. Лтд. Комбинированные способы терапии для лечения злокачественной опухоли
CN107987081B (zh) * 2016-10-26 2019-12-06 刘辉 一种二氢卟吩e6衍生物及其药学上可接受的盐、其制备方法和应用
AU2017384348B2 (en) * 2016-12-22 2024-03-07 Daiichi Sankyo Company, Limited Peptide for treating age-related macular degeneration
US10933134B2 (en) 2017-03-16 2021-03-02 Memorial Sloan Kettering Cancer Center Combination therapies for treatment of cancer
WO2019116376A1 (en) * 2017-12-17 2019-06-20 Yeda Research And Development Co. Ltd. Cop9 signalosome (csn) complex modulators and uses thereof
CN111848656B (zh) * 2020-06-24 2023-03-14 天津大学 离子修饰的原卟啉镓化合物及其制备方法和应用
CN116033913A (zh) * 2020-07-29 2023-04-28 国立大学法人北陆先端科学技术大学院大学 癌症的治疗药或诊断药
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