IL152889A0 - Imidazopyridine and imidazopyrimidine derivatives and pharmaceutical compositions containing the same - Google Patents
Imidazopyridine and imidazopyrimidine derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL152889A0 IL152889A0 IL15288901A IL15288901A IL152889A0 IL 152889 A0 IL152889 A0 IL 152889A0 IL 15288901 A IL15288901 A IL 15288901A IL 15288901 A IL15288901 A IL 15288901A IL 152889 A0 IL152889 A0 IL 152889A0
- Authority
- IL
- Israel
- Prior art keywords
- imidazopyridine
- same
- pharmaceutical compositions
- compositions containing
- imidazopyrimidine derivatives
- Prior art date
Links
- GAMYYCRTACQSBR-UHFFFAOYSA-N 4-azabenzimidazole Chemical compound C1=CC=C2NC=NC2=N1 GAMYYCRTACQSBR-UHFFFAOYSA-N 0.000 title 1
- 150000005237 imidazopyrimidines Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21144700P | 2000-06-13 | 2000-06-13 | |
| US26336301P | 2001-01-22 | 2001-01-22 | |
| PCT/US2001/014775 WO2001095910A1 (en) | 2000-06-13 | 2001-05-08 | Imidazopyridine and imidazopyrimidine antiviral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL152889A0 true IL152889A0 (en) | 2003-06-24 |
Family
ID=26906145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15288901A IL152889A0 (en) | 2000-06-13 | 2001-05-08 | Imidazopyridine and imidazopyrimidine derivatives and pharmaceutical compositions containing the same |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6489338B2 (enExample) |
| EP (1) | EP1311268A4 (enExample) |
| JP (1) | JP2004503501A (enExample) |
| KR (1) | KR20030008151A (enExample) |
| CN (1) | CN1436079A (enExample) |
| AR (1) | AR029128A1 (enExample) |
| AU (2) | AU7290601A (enExample) |
| BR (1) | BR0111569A (enExample) |
| CA (1) | CA2412327A1 (enExample) |
| CZ (1) | CZ20024078A3 (enExample) |
| HU (1) | HUP0400766A2 (enExample) |
| IL (1) | IL152889A0 (enExample) |
| MX (1) | MXPA02012204A (enExample) |
| NO (1) | NO20025977L (enExample) |
| NZ (1) | NZ523566A (enExample) |
| PE (1) | PE20011348A1 (enExample) |
| PL (1) | PL360290A1 (enExample) |
| RU (1) | RU2003100828A (enExample) |
| UY (1) | UY26758A1 (enExample) |
| WO (1) | WO2001095910A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6774134B2 (en) * | 2000-12-20 | 2004-08-10 | Bristol-Myers Squibb Company | Heterocyclic substituted 2-methyl-benzimidazole antiviral agents |
| US6919331B2 (en) * | 2001-12-10 | 2005-07-19 | Bristol-Myers Squibb Company | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents |
| HUP0402535A2 (hu) | 2001-12-10 | 2005-04-28 | Bristol-Myers Squibb Co. | RSV fúzió inhibitor hatású imidazo-piridin-vegyület dihidroklorid-monohidrát sója és az ezt tartalmazó gyógyszerkészítmények |
| WO2004043913A2 (en) * | 2002-11-08 | 2004-05-27 | Trimeris, Inc. | Hetero-substituted benzimidazole compounds and antiviral uses thereof |
| JP2007501251A (ja) * | 2003-08-05 | 2007-01-25 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答調節剤化合物を使用する感染予防 |
| EP1682547B1 (en) | 2003-10-30 | 2012-10-24 | Boehringer Ingelheim (Canada) Ltd. | Rsv polymerase inhibitors |
| EP2287167A1 (en) | 2003-12-24 | 2011-02-23 | Biota Scientific Management Pty. Ltd. | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| GB0406282D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Therapeutic compounds |
| GB0406279D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Therapeutic compounds |
| AU2005287407B2 (en) * | 2004-07-27 | 2011-11-17 | Gilead Sciences, Inc. | Imidazo(4,5-d)pyrimidines, their uses and methods of preparation |
| RU2441866C2 (ru) | 2005-06-20 | 2012-02-10 | Тиботек Фармасьютикалз Лтд | 2-замещенные бензимидазолы |
| US8034835B2 (en) | 2005-06-20 | 2011-10-11 | Tibotec Pharmaceuticals Ltd. | 1-[[2-amino-3-(substituted alkyl)-3H-benzimidazolyl[methyl]-3-substituted-1,3-dihydro-benzoimidazol-2-ones and structural analogs |
| WO2006136562A1 (en) | 2005-06-20 | 2006-12-28 | Tibotec Pharmaceuticals Ltd | Heterocyclylaminoalkyl substituted benzimidazoles |
| TWI423972B (zh) | 2006-09-28 | 2014-01-21 | Biota Scient Management | 治療呼吸系融合細胞病毒感染之多環劑 |
| WO2009084544A1 (ja) * | 2007-12-27 | 2009-07-09 | Idemitsu Kosan Co., Ltd. | 含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
| US20100278835A1 (en) | 2009-03-10 | 2010-11-04 | Astrazeneca Uk Limited | Novel compounds 660 |
| RU2407738C1 (ru) * | 2009-07-03 | 2010-12-27 | Общество с ограниченной ответственностью "Интеллектуальный Диалог" | Противовирусный активный компонент, фармацевтическая композиция, лекарственное средство, способ лечения вирусных заболеваний |
| TWI508968B (zh) | 2010-02-08 | 2015-11-21 | Biota Scient Management | 用於治療呼吸道融合性病毒感染的化合物 |
| JPWO2011115150A1 (ja) * | 2010-03-18 | 2013-07-04 | 興和株式会社 | ベンゾチアジン化合物の製造方法 |
| US8796303B2 (en) | 2010-11-26 | 2014-08-05 | Biota Scientific Management Pty Ltd. | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections |
| TWI530495B (zh) * | 2010-12-16 | 2016-04-21 | 健生科學愛爾蘭無限公司 | 苯并咪唑呼吸道融合病毒抑制劑 |
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI541241B (zh) * | 2010-12-16 | 2016-07-11 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類 |
| TWI527814B (zh) | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
| TWI501967B (zh) * | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| CN103860538B (zh) * | 2011-03-23 | 2016-03-02 | 上海市第一人民医院 | 靶向人La蛋白的先导化合物及其在制备抗乙型肝炎病毒的药物中的用途 |
| EA028626B1 (ru) * | 2012-06-11 | 2017-12-29 | Юсб Байофарма Спрл | БЕНЗИМИДАЗОЛЫ, МОДУЛИРУЮЩИЕ TNF-α |
| EP2864299A1 (en) * | 2012-06-15 | 2015-04-29 | Janssen Sciences Ireland UC | 4 - substituted 1, 3 - dihydro - 2h - benzimidazol - 2 - one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents |
| JP6259451B2 (ja) | 2012-06-15 | 2018-01-10 | ヤンセン・サイエンシズ・アイルランド・ユーシー | Ｒｓウイルス抗ウイルス薬としての、複素環によって置換された新規１，３−ジヒドロ−２ｈ−ベンゾイミダゾル−２−オン誘導体 |
| JP2015519387A (ja) * | 2012-06-15 | 2015-07-09 | ヤンセン・アールアンドデイ・アイルランド | Ｒｓウイルス抗ウイルス薬としての、複素環によって置換された新規４−置換１，３−ジヒドロ−２ｈ−ベンゾイミダゾル−２−オン誘導体 |
| CN104470916A (zh) * | 2012-06-15 | 2015-03-25 | 爱尔兰詹森研发公司 | 新颖的作为呼吸道合胞病毒抗病毒剂的被苯并咪唑取代的1,3-二氢-2h-苯并咪唑-2-酮衍生物 |
| NZ705759A (en) * | 2012-10-16 | 2019-01-25 | Janssen Sciences Ireland Uc | Rsv antiviral compounds |
| JP2016145155A (ja) * | 2013-04-30 | 2016-08-12 | 日本農薬株式会社 | フタルアミド誘導体及び該誘導体を含有する農園芸用殺虫剤並びにその使用方法 |
| US9708332B2 (en) | 2013-10-29 | 2017-07-18 | Medivir Ab | Respiratory syncytial virus inhibitors |
| WO2015065336A1 (en) * | 2013-10-29 | 2015-05-07 | Medivir Ab | Respiratory syncytial virus inhibitors |
| WO2017066014A1 (en) * | 2015-10-14 | 2017-04-20 | Sunnylife Pharma Inc. | Bruton's tyrosine kinase inhibitors |
| WO2019046364A1 (en) * | 2017-08-29 | 2019-03-07 | Emory University | INHIBITORS OF SYNCYTIAL RESPIRATORY VIRUS (RSV) REPLICATION AND USES THEREOF |
| IL292526A (en) * | 2019-10-30 | 2022-06-01 | Janssen Sciences Ireland Unlimited Co | Synthesis of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1h-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-3,1-dihydro- 2h-Imidazo[5,4-c]pyridin-2-one |
| BR112022007208A2 (pt) | 2019-10-30 | 2022-07-26 | Janssen Sciences Ireland Unlimited Co | Síntese de 3-nitro-n-(2,2,2-trifluoroetil)-4-piridinamina |
| EP4165034A1 (en) | 2020-06-11 | 2023-04-19 | Janssen Sciences Ireland Unlimited Company | Hemi (l)-tartrate forms of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1h-indol-2 yl} methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2h-imidazo[4,5-c]pyridin-2-one and pharmaceutical compositions comprising the same |
| WO2022184606A1 (en) * | 2021-03-01 | 2022-09-09 | Janssen Sciences Ireland Unlimited Company | Synthesis of rilematovir |
| EP4469456A4 (en) * | 2022-01-28 | 2025-12-31 | Insilico Medicine Ip Ltd | Ectunocleotide pyrophosphatase-phosphodiesterase 1 (ENPP1) inhibitors and their uses |
| WO2025026383A1 (en) * | 2023-08-02 | 2025-02-06 | Insilico Medicine Ip Limited | Crytsalline forms of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp1) inhibitors and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4324794A (en) | 1980-08-26 | 1982-04-13 | Research Triangle Institute | Inhibition of respiratory syncytial virus-induced cell fusion by amidino compounds |
| NO155805C (no) | 1981-02-06 | 1987-06-10 | Ucb Sa | Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter. |
| US5256668A (en) | 1993-03-17 | 1993-10-26 | American Home Products Corporation | Aminopyrimidine derivatives as antiviral agents for respiratory syncytial virus |
| ZA971185B (en) | 1996-02-13 | 1998-08-12 | American Cyanamid Co | Triazine containing compounds useful as antiviral agents |
| NZ505894A (en) | 1998-01-29 | 2002-12-20 | Viropharma Inc | Methylenebisbenzaldehyde derivatives, methylidynetrisphenol derivative and pharmaceuticals thereof; useful for treating or preventing pneumovirus infection and associated diseases |
| WO2000004900A1 (en) | 1998-07-20 | 2000-02-03 | Bristol-Myers Squibb Company | Substituted benzimidazole antiviral agents |
| EP1196410B1 (en) | 1999-06-28 | 2004-02-18 | Janssen Pharmaceutica N.V. | Respiratory syncytial virus replication inhibitors |
-
2001
- 2001-04-23 US US09/840,279 patent/US6489338B2/en not_active Expired - Fee Related
- 2001-05-08 EP EP01952114A patent/EP1311268A4/en not_active Withdrawn
- 2001-05-08 BR BR0111569-3A patent/BR0111569A/pt not_active IP Right Cessation
- 2001-05-08 NZ NZ523566A patent/NZ523566A/en unknown
- 2001-05-08 CA CA002412327A patent/CA2412327A1/en not_active Abandoned
- 2001-05-08 MX MXPA02012204A patent/MXPA02012204A/es unknown
- 2001-05-08 PL PL36029001A patent/PL360290A1/xx not_active Application Discontinuation
- 2001-05-08 RU RU2003100828/15A patent/RU2003100828A/ru not_active Application Discontinuation
- 2001-05-08 WO PCT/US2001/014775 patent/WO2001095910A1/en not_active Ceased
- 2001-05-08 AU AU7290601A patent/AU7290601A/xx active Pending
- 2001-05-08 HU HU0400766A patent/HUP0400766A2/hu unknown
- 2001-05-08 KR KR1020027016924A patent/KR20030008151A/ko not_active Ceased
- 2001-05-08 CN CN01811136A patent/CN1436079A/zh active Pending
- 2001-05-08 IL IL15288901A patent/IL152889A0/xx unknown
- 2001-05-08 JP JP2002510088A patent/JP2004503501A/ja not_active Withdrawn
- 2001-05-08 AU AU2001272906A patent/AU2001272906B2/en not_active Ceased
- 2001-05-08 CZ CZ20024078A patent/CZ20024078A3/cs unknown
- 2001-06-11 UY UY26758A patent/UY26758A1/es not_active Application Discontinuation
- 2001-06-12 AR ARP010102772A patent/AR029128A1/es unknown
- 2001-06-13 PE PE2001000559A patent/PE20011348A1/es not_active Application Discontinuation
-
2002
- 2002-12-12 NO NO20025977A patent/NO20025977L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR029128A1 (es) | 2003-06-04 |
| NZ523566A (en) | 2004-08-27 |
| CN1436079A (zh) | 2003-08-13 |
| NO20025977D0 (no) | 2002-12-12 |
| JP2004503501A (ja) | 2004-02-05 |
| US20020016309A1 (en) | 2002-02-07 |
| MXPA02012204A (es) | 2003-10-15 |
| CA2412327A1 (en) | 2001-12-20 |
| CZ20024078A3 (cs) | 2003-08-13 |
| UY26758A1 (es) | 2002-01-31 |
| PE20011348A1 (es) | 2002-02-07 |
| KR20030008151A (ko) | 2003-01-24 |
| EP1311268A4 (en) | 2004-06-30 |
| AU7290601A (en) | 2001-12-24 |
| US6489338B2 (en) | 2002-12-03 |
| HUP0400766A2 (hu) | 2004-07-28 |
| EP1311268A1 (en) | 2003-05-21 |
| BR0111569A (pt) | 2003-04-29 |
| NO20025977L (no) | 2003-01-29 |
| WO2001095910A1 (en) | 2001-12-20 |
| RU2003100828A (ru) | 2004-06-27 |
| AU2001272906B2 (en) | 2004-08-26 |
| PL360290A1 (en) | 2004-09-06 |
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