NO20025977L - Imidazopyridin - og imidazopyrimidin antivirale forbindelser - Google Patents

Imidazopyridin - og imidazopyrimidin antivirale forbindelser

Info

Publication number
NO20025977L
NO20025977L NO20025977A NO20025977A NO20025977L NO 20025977 L NO20025977 L NO 20025977L NO 20025977 A NO20025977 A NO 20025977A NO 20025977 A NO20025977 A NO 20025977A NO 20025977 L NO20025977 L NO 20025977L
Authority
NO
Norway
Prior art keywords
imidazopyridine
antiviral compounds
imidazopyrimidine
imidazopyrimidine antiviral
compounds
Prior art date
Application number
NO20025977A
Other languages
English (en)
Other versions
NO20025977D0 (no
Inventor
Kuo-Long Yu
Rita L Civiello
Keith Dean Combrink
Hatice Bel Guelgeze
Ny Sin
Xiangdong Wang
Nicholas A Meanwell
Brian Lee Venables
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20025977D0 publication Critical patent/NO20025977D0/no
Publication of NO20025977L publication Critical patent/NO20025977L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20025977A 2000-06-13 2002-12-12 Imidazopyridin - og imidazopyrimidin antivirale forbindelser NO20025977L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21144700P 2000-06-13 2000-06-13
US26336301P 2001-01-22 2001-01-22
PCT/US2001/014775 WO2001095910A1 (en) 2000-06-13 2001-05-08 Imidazopyridine and imidazopyrimidine antiviral agents

Publications (2)

Publication Number Publication Date
NO20025977D0 NO20025977D0 (no) 2002-12-12
NO20025977L true NO20025977L (no) 2003-01-29

Family

ID=26906145

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20025977A NO20025977L (no) 2000-06-13 2002-12-12 Imidazopyridin - og imidazopyrimidin antivirale forbindelser

Country Status (20)

Country Link
US (1) US6489338B2 (no)
EP (1) EP1311268A4 (no)
JP (1) JP2004503501A (no)
KR (1) KR20030008151A (no)
CN (1) CN1436079A (no)
AR (1) AR029128A1 (no)
AU (2) AU2001272906B2 (no)
BR (1) BR0111569A (no)
CA (1) CA2412327A1 (no)
CZ (1) CZ20024078A3 (no)
HU (1) HUP0400766A2 (no)
IL (1) IL152889A0 (no)
MX (1) MXPA02012204A (no)
NO (1) NO20025977L (no)
NZ (1) NZ523566A (no)
PE (1) PE20011348A1 (no)
PL (1) PL360290A1 (no)
RU (1) RU2003100828A (no)
UY (1) UY26758A1 (no)
WO (1) WO2001095910A1 (no)

Families Citing this family (39)

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US6774134B2 (en) * 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
US6919331B2 (en) * 2001-12-10 2005-07-19 Bristol-Myers Squibb Company Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
PL369432A1 (en) 2001-12-10 2005-04-18 Bristol-Myers Squibb Company Bis hydrochloride monohydrate salt of rsv fusion inhibitor
AU2003294249A1 (en) * 2002-11-08 2004-06-03 Trimeris, Inc. Hetero-substituted benzimidazole compounds and antiviral uses thereof
EP1651216A2 (en) * 2003-08-05 2006-05-03 3M Innovative Properties Company Infection prophylaxis using immune response modifier compounds
EP1682547B1 (en) 2003-10-30 2012-10-24 Boehringer Ingelheim (Canada) Ltd. Rsv polymerase inhibitors
KR20060127909A (ko) * 2003-12-24 2006-12-13 비오타 사이언티픽 매니지먼트 피티와이 엘티디 호흡기 다핵체 바이러스 감염 치료용 다환 물질
GB0406279D0 (en) * 2004-03-19 2004-04-21 Arrow Therapeutics Ltd Therapeutic compounds
GB0406282D0 (en) * 2004-03-19 2004-04-21 Arrow Therapeutics Ltd Therapeutic compounds
BRPI0513811A (pt) * 2004-07-27 2008-07-15 Gilead Sciences Inc imidazo [4,5-d] pirimidinas, seus usos e processos de preparação
EP1896449B1 (en) 2005-06-20 2013-11-06 Janssen R&D Ireland Heterocyclylaminoalkyl substituted benzimidazoles
RU2441866C2 (ru) 2005-06-20 2012-02-10 Тиботек Фармасьютикалз Лтд 2-замещенные бензимидазолы
JP5078887B2 (ja) * 2005-06-20 2012-11-21 テイボテク・フアーマシユーチカルズ 呼吸器シンシチウムウイルスに活性をもつ、１−（２−アミノ−３−（置換アルキル）−３ｈ−ベンズイミダゾイルメチル）−３−置換−１，３−ジヒドロ−ベンゾイミダゾル−２−オン
TWI423972B (zh) 2006-09-28 2014-01-21 Biota Scient Management 治療呼吸系融合細胞病毒感染之多環劑
WO2009084544A1 (ja) * 2007-12-27 2009-07-09 Idemitsu Kosan Co., Ltd. 含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子
WO2010103306A1 (en) 2009-03-10 2010-09-16 Astrazeneca Uk Limited Benzimidazole derivatives and their use as antivaral agents
TWI508968B (zh) 2010-02-08 2015-11-21 Biota Scient Management 用於治療呼吸道融合性病毒感染的化合物
WO2011115150A1 (ja) * 2010-03-18 2011-09-22 興和株式会社 ベンゾチアジン化合物の製造方法
US8796303B2 (en) 2010-11-26 2014-08-05 Biota Scientific Management Pty Ltd. Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections
TWI541241B (zh) 2010-12-16 2016-07-11 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類
TWI515187B (zh) * 2010-12-16 2016-01-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之吲哚類
TWI501967B (zh) 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
TWI527814B (zh) * 2010-12-16 2016-04-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類
TWI530495B (zh) 2010-12-16 2016-04-21 健生科學愛爾蘭無限公司 苯并咪唑呼吸道融合病毒抑制劑
CN103860538B (zh) * 2011-03-23 2016-03-02 上海市第一人民医院 靶向人La蛋白的先导化合物及其在制备抗乙型肝炎病毒的药物中的用途
US9550737B2 (en) * 2012-06-11 2017-01-24 Ucb Biopharma Sprl TNF -α modulating benzimidazoles
CA2873920C (en) * 2012-06-15 2021-07-20 Janssen R&D Ireland 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents
KR20150028969A (ko) * 2012-06-15 2015-03-17 얀센 알 앤드 디 아일랜드 호흡기 합포체 바이러스의 항바이러스제로서의 벤즈이미다졸로 치환된 4-치환된 1,3-디하이드로-2h-벤즈이미다졸-2-온 유도체
AU2013276521A1 (en) * 2012-06-15 2014-12-04 Janssen Sciences Ireland Uc 1,3 -dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents
EA201590020A1 (ru) * 2012-06-15 2015-03-31 ЯНССЕН Ар ЭНД Ди АЙРЛЭНД Новые производные 1,3-дигидро-2h-бензимидазол-2-она, замещенные бензимидазолами, в качестве противовирусных средств против респираторного синцитиального вируса
MY172021A (en) * 2012-10-16 2019-11-12 Janssen Sciences Ireland Uc Rsv antiviral compounds
JP2016145155A (ja) * 2013-04-30 2016-08-12 日本農薬株式会社 フタルアミド誘導体及び該誘導体を含有する農園芸用殺虫剤並びにその使用方法
EP3063149A1 (en) * 2013-10-29 2016-09-07 Medivir Ab Quinazoline based respiratory syncytial virus inhibitors
WO2015065336A1 (en) * 2013-10-29 2015-05-07 Medivir Ab Respiratory syncytial virus inhibitors
CA3008653A1 (en) * 2015-10-14 2017-04-20 Zibo Biopolar Changsheng Pharmaceutical Co. Ltd. Bruton's tyrosine kinase inhibitors
WO2019046364A1 (en) * 2017-08-29 2019-03-07 Emory University INHIBITORS OF SYNCYTIAL RESPIRATORY VIRUS (RSV) REPLICATION AND USES THEREOF
CA3151904A1 (en) * 2019-10-30 2021-05-06 Hongyu TAN Synthesis of 3-nitro-n-(2,2,2-trifluoroethyl)-4-pyridinamine
WO2022184606A1 (en) * 2021-03-01 2022-09-09 Janssen Sciences Ireland Unlimited Company Synthesis of rilematovir
WO2023143520A1 (en) * 2022-01-28 2023-08-03 Insilico Medicine Ip Limited Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp1) inhibitors and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4324794A (en) 1980-08-26 1982-04-13 Research Triangle Institute Inhibition of respiratory syncytial virus-induced cell fusion by amidino compounds
NO155805C (no) 1981-02-06 1987-06-10 Ucb Sa Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter.
US5256668A (en) 1993-03-17 1993-10-26 American Home Products Corporation Aminopyrimidine derivatives as antiviral agents for respiratory syncytial virus
BR9700939A (pt) 1996-02-13 1998-09-01 American Cyanamid Co Compostos aniônicos contendo traiazina úteis como agentes antivirais
BR9908522A (pt) 1998-01-29 2001-10-02 Viropharma Inc Composto, pró-droga, intermediário para a preparação de um composto, composição farmacêutica, processos para tratar e prevenir infecção por pneumovìrus, para tratar células em cultura, para tratar materiais biológicos, e, para preparar um composto
CA2338147A1 (en) 1998-07-20 2000-02-03 Kuo-Long Yu Substituted benzimidazole antiviral agents
BR0011997A (pt) 1999-06-28 2002-03-05 Janssen Pharmaceutica Nv Inibidores da replicação do vìrus sincicial respiratório

Also Published As

Publication number Publication date
EP1311268A4 (en) 2004-06-30
IL152889A0 (en) 2003-06-24
JP2004503501A (ja) 2004-02-05
AU2001272906B2 (en) 2004-08-26
PE20011348A1 (es) 2002-02-07
NZ523566A (en) 2004-08-27
CN1436079A (zh) 2003-08-13
RU2003100828A (ru) 2004-06-27
EP1311268A1 (en) 2003-05-21
MXPA02012204A (es) 2003-10-15
UY26758A1 (es) 2002-01-31
WO2001095910A1 (en) 2001-12-20
US20020016309A1 (en) 2002-02-07
KR20030008151A (ko) 2003-01-24
AU7290601A (en) 2001-12-24
CZ20024078A3 (cs) 2003-08-13
HUP0400766A2 (hu) 2004-07-28
PL360290A1 (en) 2004-09-06
US6489338B2 (en) 2002-12-03
BR0111569A (pt) 2003-04-29
NO20025977D0 (no) 2002-12-12
AR029128A1 (es) 2003-06-04
CA2412327A1 (en) 2001-12-20

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application