AU7290601A - Imidazopyridine and imidazopyrimidine antiviral agents - Google Patents

Imidazopyridine and imidazopyrimidine antiviral agents

Info

Publication number
AU7290601A
AU7290601A AU7290601A AU7290601A AU7290601A AU 7290601 A AU7290601 A AU 7290601A AU 7290601 A AU7290601 A AU 7290601A AU 7290601 A AU7290601 A AU 7290601A AU 7290601 A AU7290601 A AU 7290601A
Authority
AU
Australia
Prior art keywords
imidazopyridine
antiviral agents
imidazopyrimidine
imidazopyrimidine antiviral
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU7290601A
Other languages
English (en)
Inventor
Kuo-Long Yu
Rita L Civiello
Keith D Combrink
Hatice Belgin Gulgeze
Ny Sin
Xiangdong Wang
Nicholas A Meanwell
Brian Lee Venables
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AU7290601A publication Critical patent/AU7290601A/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU7290601A 2000-06-13 2001-05-08 Imidazopyridine and imidazopyrimidine antiviral agents Pending AU7290601A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21144700P 2000-06-13 2000-06-13
US26336301P 2001-01-22 2001-01-22
PCT/US2001/014775 WO2001095910A1 (en) 2000-06-13 2001-05-08 Imidazopyridine and imidazopyrimidine antiviral agents

Publications (1)

Publication Number Publication Date
AU7290601A true AU7290601A (en) 2001-12-24

Family

ID=26906145

Family Applications (2)

Application Number Title Priority Date Filing Date
AU7290601A Pending AU7290601A (en) 2000-06-13 2001-05-08 Imidazopyridine and imidazopyrimidine antiviral agents
AU2001272906A Ceased AU2001272906B2 (en) 2000-06-13 2001-05-08 Imidazopyridine and imidazopyrimidine antiviral agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001272906A Ceased AU2001272906B2 (en) 2000-06-13 2001-05-08 Imidazopyridine and imidazopyrimidine antiviral agents

Country Status (20)

Country Link
US (1) US6489338B2 (enExample)
EP (1) EP1311268A4 (enExample)
JP (1) JP2004503501A (enExample)
KR (1) KR20030008151A (enExample)
CN (1) CN1436079A (enExample)
AR (1) AR029128A1 (enExample)
AU (2) AU7290601A (enExample)
BR (1) BR0111569A (enExample)
CA (1) CA2412327A1 (enExample)
CZ (1) CZ20024078A3 (enExample)
HU (1) HUP0400766A2 (enExample)
IL (1) IL152889A0 (enExample)
MX (1) MXPA02012204A (enExample)
NO (1) NO20025977L (enExample)
NZ (1) NZ523566A (enExample)
PE (1) PE20011348A1 (enExample)
PL (1) PL360290A1 (enExample)
RU (1) RU2003100828A (enExample)
UY (1) UY26758A1 (enExample)
WO (1) WO2001095910A1 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774134B2 (en) * 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
US6919331B2 (en) * 2001-12-10 2005-07-19 Bristol-Myers Squibb Company Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
US6737428B2 (en) 2001-12-10 2004-05-18 Bristol-Myers Squibb Company BIS hydrochloride monohydrate salt of RSV fusion inhibitor
US20040166137A1 (en) * 2002-11-08 2004-08-26 Lackey John William Hetero-substituted benzimidazole compounds and antiviral uses thereof
JP2007501252A (ja) * 2003-08-05 2007-01-25 スリーエム イノベイティブ プロパティズ カンパニー 免疫応答調整剤を含有する製剤
WO2005042530A1 (en) 2003-10-30 2005-05-12 Boehringer Ingelheim (Canada) Ltd. Rsv polymerase inhibitors
CA2551178C (en) * 2003-12-24 2012-11-06 Biota Scientific Management Pty Ltd Polycyclic agents for the treatment of respiratory syncytial virus infections
GB0406282D0 (en) * 2004-03-19 2004-04-21 Arrow Therapeutics Ltd Therapeutic compounds
GB0406279D0 (en) * 2004-03-19 2004-04-21 Arrow Therapeutics Ltd Therapeutic compounds
CN101027303A (zh) 2004-07-27 2007-08-29 吉里德科学公司 咪唑并[4，5－d]嘧啶类、其应用和制备方法
MX2007016311A (es) 2005-06-20 2008-03-07 Tibotec Pharm Ltd Bencimidazoles sustituidos con heterociclilaminoalquilo.
AU2006260969B2 (en) * 2005-06-20 2011-11-17 Janssen Sciences Ireland Uc 1- ( 2-amino-3- (substituted alkyl)-3H-benzimidazolylmethyl) -3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus
PL1896450T3 (pl) 2005-06-20 2013-01-31 Janssen Sciences Ireland Uc 2-podstawione benzimidazole
TWI423972B (zh) 2006-09-28 2014-01-21 Biota Scient Management 治療呼吸系融合細胞病毒感染之多環劑
WO2009084544A1 (ja) * 2007-12-27 2009-07-09 Idemitsu Kosan Co., Ltd. 含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子
US20100278835A1 (en) 2009-03-10 2010-11-04 Astrazeneca Uk Limited Novel compounds 660
RU2407738C1 (ru) * 2009-07-03 2010-12-27 Общество с ограниченной ответственностью "Интеллектуальный Диалог" Противовирусный активный компонент, фармацевтическая композиция, лекарственное средство, способ лечения вирусных заболеваний
TWI508968B (zh) 2010-02-08 2015-11-21 Biota Scient Management 用於治療呼吸道融合性病毒感染的化合物
WO2011115150A1 (ja) * 2010-03-18 2011-09-22 興和株式会社 ベンゾチアジン化合物の製造方法
US8796303B2 (en) 2010-11-26 2014-08-05 Biota Scientific Management Pty Ltd. Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections
TWI541241B (zh) 2010-12-16 2016-07-11 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類
TWI530495B (zh) * 2010-12-16 2016-04-21 健生科學愛爾蘭無限公司 苯并咪唑呼吸道融合病毒抑制劑
TWI501967B (zh) 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
TWI527814B (zh) * 2010-12-16 2016-04-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類
TWI515187B (zh) 2010-12-16 2016-01-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之吲哚類
CN103860538B (zh) * 2011-03-23 2016-03-02 上海市第一人民医院 靶向人La蛋白的先导化合物及其在制备抗乙型肝炎病毒的药物中的用途
CA2874303C (en) * 2012-06-11 2020-10-13 Ucb Biopharma Sprl Tnf -alpha modulating benz imidazoles
JP2015519387A (ja) * 2012-06-15 2015-07-09 ヤンセン・アールアンドデイ・アイルランド Ｒｓウイルス抗ウイルス薬としての、複素環によって置換された新規４−置換１，３−ジヒドロ−２ｈ−ベンゾイミダゾル−２−オン誘導体
WO2013186334A1 (en) * 2012-06-15 2013-12-19 Janssen R&D Ireland 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents
JP2015519385A (ja) * 2012-06-15 2015-07-09 ヤンセン・アールアンドデイ・アイルランド Ｒｓウイルス抗ウイルス薬としての、ベンゾイミダゾールによって置換された新規４−置換１，３−ジヒドロ−２ｈ−ベンゾイミダゾル−２−オン誘導体
CA2873920C (en) 2012-06-15 2021-07-20 Janssen R&D Ireland 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents
AU2013334001B2 (en) * 2012-10-16 2017-07-20 Janssen Sciences Ireland Uc RSV antiviral compounds
JP2016145155A (ja) * 2013-04-30 2016-08-12 日本農薬株式会社 フタルアミド誘導体及び該誘導体を含有する農園芸用殺虫剤並びにその使用方法
RU2016120763A (ru) * 2013-10-29 2017-12-05 Медивир Аб Ингибиторы респираторного синцитиального вируса
WO2015065336A1 (en) * 2013-10-29 2015-05-07 Medivir Ab Respiratory syncytial virus inhibitors
US10358446B2 (en) 2015-10-14 2019-07-23 Zibo Biopolar Changsheng Pharmaceutical Co., Ltd. Bruton's tyrosine kinase inhibitors
WO2019046364A1 (en) * 2017-08-29 2019-03-07 Emory University INHIBITORS OF SYNCYTIAL RESPIRATORY VIRUS (RSV) REPLICATION AND USES THEREOF
BR112022007208A2 (pt) * 2019-10-30 2022-07-26 Janssen Sciences Ireland Unlimited Co Síntese de 3-nitro-n-(2,2,2-trifluoroetil)-4-piridinamina
PH12022551042A1 (en) * 2019-10-30 2023-05-29 Janssen Sciences Ireland Unlimited Co Synthesis of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1h-indol-2 yl} methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2h-imidazo[4,5-c]pyridin-2-one
JP2023528969A (ja) 2020-06-11 2023-07-06 ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー ３－（｛５－クロロ－１－［３－（メチルスルホニル）プロピル］－１Ｈ－インドール－２ イル｝メチル）－１－（２，２，２－トリフルオロエチル）－１，３－ジヒドロ－２Ｈ－イミダゾ［４，５－ｃ］ピリジン－２－オンのヘミ（Ｌ）－酒石酸塩形態及びそれを含む医薬組成物
WO2022184606A1 (en) * 2021-03-01 2022-09-09 Janssen Sciences Ireland Unlimited Company Synthesis of rilematovir
MX2024009216A (es) * 2022-01-28 2024-08-06 Insilico Medicine Ip Ltd Inhibidores de ectonucleotido pirofosfatasa-fosfodiesterasa 1 (enpp1) y usos de los mismos.
CN117586250A (zh) * 2022-08-11 2024-02-23 潍坊汇韬化工有限公司 一种人类呼吸道合胞病毒抑制剂中间体的制备方法
CN116589399A (zh) * 2023-05-29 2023-08-15 济南大学 一种3-甲氧基-2-硝基吡啶的制备方法
CN121969621A (zh) * 2023-08-02 2026-05-01 英矽智能科技知识产权有限公司 外核苷酸焦磷酸酶-磷酸二酯酶1 (enpp1)抑制剂的结晶形式及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4324794A (en) 1980-08-26 1982-04-13 Research Triangle Institute Inhibition of respiratory syncytial virus-induced cell fusion by amidino compounds
NO155805C (no) 1981-02-06 1987-06-10 Ucb Sa Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter.
US5256668A (en) 1993-03-17 1993-10-26 American Home Products Corporation Aminopyrimidine derivatives as antiviral agents for respiratory syncytial virus
ZA971185B (en) 1996-02-13 1998-08-12 American Cyanamid Co Triazine containing compounds useful as antiviral agents
CN1289248A (zh) 1998-01-29 2001-03-28 维洛药品公司 治疗或预防肺病毒感染及有关疾病的化合物、组合物和方法
JP2002521334A (ja) 1998-07-20 2002-07-16 ブリストルーマイヤーズ スクイブ カンパニー 置換ベンズイミダゾール抗ウィルス剤
JP2003503403A (ja) 1999-06-28 2003-01-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 呼吸合胞体ウイルス複製阻害剤

Also Published As

Publication number Publication date
NZ523566A (en) 2004-08-27
PE20011348A1 (es) 2002-02-07
CZ20024078A3 (cs) 2003-08-13
EP1311268A1 (en) 2003-05-21
CN1436079A (zh) 2003-08-13
PL360290A1 (en) 2004-09-06
CA2412327A1 (en) 2001-12-20
BR0111569A (pt) 2003-04-29
WO2001095910A1 (en) 2001-12-20
US6489338B2 (en) 2002-12-03
MXPA02012204A (es) 2003-10-15
NO20025977D0 (no) 2002-12-12
NO20025977L (no) 2003-01-29
AR029128A1 (es) 2003-06-04
IL152889A0 (en) 2003-06-24
JP2004503501A (ja) 2004-02-05
HUP0400766A2 (hu) 2004-07-28
AU2001272906B2 (en) 2004-08-26
RU2003100828A (ru) 2004-06-27
KR20030008151A (ko) 2003-01-24
EP1311268A4 (en) 2004-06-30
UY26758A1 (es) 2002-01-31
US20020016309A1 (en) 2002-02-07

Similar Documents

Publication Publication Date Title
PL360290A1 (en) Imidazopyridine and imidazopyrimidine antiviral agents
SI1278750T1 (en) Imidazopyrimidine derivatives and triazolopyrimidine derivatives
EP1187827A4 (en) ANTIVIRAL ACTIVE SUBSTANCE
HU229992B1 (hu) Antivirális hatású aza-indol-származékok
IL144171A0 (en) Quinolinecarboxamides as antiviral agents
HUP0301614A3 (en) Pyrido[2,3-d]pyrimidini and pyrimido[4,5-d]pyrimidini nucleosides
AU2002221344A1 (en) Antiviral agents
PT1518792E (pt) Estrutura de pega e prancha
IL177316A0 (en) Diazabicyclic central nervous system active agents
IL160402A0 (en) Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido {1,2-a} pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo{1,2-pyrimidin-5 (1h) one derivatives
AU1224902A (en) 2-pyridinyl-6,7,8,9-tetrahydropyrimido(1,2-a)pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo(1,2-a)pyrimidin-5(1H)one derivatives
DE60015325D1 (en) Offset-kompensation in analog-digital wandlern
PL341819A1 (en) Antiviral agents
GB0109060D0 (en) Multi-purpose attachment device
HK1054510A (en) Imidazopyridine and imidazopyrimidine antiviral agents
AU2001281142A1 (en) Diazepinones as antiviral agents
GB2349652B (en) Padded surfaces
GB0012497D0 (en) Antiviral therapy
GB0105461D0 (en) Baby`s vest
AUPP942599A0 (en) Antiviral agents
TW435877U (en) Multi-purpose laser device
GB0009643D0 (en) Holographic-3 dimensional floor and walltile
AU2001263668A1 (en) Antiviral agents
AUPQ888900A0 (en) Antiviral agents
GB2367242B (en) Antiviral treatment