IL148803A0 - Novel composition and method for stabilizing the same - Google Patents

Novel composition and method for stabilizing the same

Info

Publication number
IL148803A0
IL148803A0 IL14880300A IL14880300A IL148803A0 IL 148803 A0 IL148803 A0 IL 148803A0 IL 14880300 A IL14880300 A IL 14880300A IL 14880300 A IL14880300 A IL 14880300A IL 148803 A0 IL148803 A0 IL 148803A0
Authority
IL
Israel
Prior art keywords
stabilizing
same
novel composition
novel
composition
Prior art date
Application number
IL14880300A
Other languages
English (en)
Original Assignee
Sucampo Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22573018&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL148803(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo Ag filed Critical Sucampo Ag
Publication of IL148803A0 publication Critical patent/IL148803A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL14880300A 1999-10-15 2000-10-13 Novel composition and method for stabilizing the same IL148803A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15954999P 1999-10-15 1999-10-15
PCT/JP2000/007109 WO2001027099A2 (en) 1999-10-15 2000-10-13 Bicyclic compounds composition and method for stabilizing the same

Publications (1)

Publication Number Publication Date
IL148803A0 true IL148803A0 (en) 2002-09-12

Family

ID=22573018

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14880300A IL148803A0 (en) 1999-10-15 2000-10-13 Novel composition and method for stabilizing the same
IL148803A IL148803A (en) 1999-10-15 2002-03-21 Preparations and methods for stabilizing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL148803A IL148803A (en) 1999-10-15 2002-03-21 Preparations and methods for stabilizing them

Country Status (26)

Country Link
US (5) US6583174B1 (zh)
EP (2) EP1426361B2 (zh)
JP (2) JP4332316B2 (zh)
KR (1) KR100830061B1 (zh)
CN (1) CN1268623C (zh)
AR (3) AR026046A1 (zh)
AT (2) ATE267189T1 (zh)
AU (2) AU780342B2 (zh)
BR (1) BRPI0014869B8 (zh)
CA (1) CA2385732C (zh)
CZ (1) CZ303625B6 (zh)
DE (2) DE60010913T2 (zh)
DK (2) DK1220849T3 (zh)
ES (2) ES2309410T5 (zh)
HK (2) HK1066792A1 (zh)
HU (2) HU230484B1 (zh)
IL (2) IL148803A0 (zh)
MX (1) MXPA02003756A (zh)
NO (1) NO330258B1 (zh)
NZ (1) NZ518020A (zh)
PT (2) PT1426361E (zh)
RU (1) RU2695274C3 (zh)
TR (1) TR200201032T2 (zh)
TW (1) TWI281918B (zh)
WO (1) WO2001027099A2 (zh)
ZA (1) ZA200202312B (zh)

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CN1268623C (zh) * 1999-10-15 2006-08-09 苏坎波公司 组合物和使该组合物稳定的方法
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
AR037524A1 (es) * 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
FR2842810B1 (fr) * 2002-07-25 2006-01-27 Inst Nat Sciences Appliq Nouveaux composes gem difluores, leur procedes de preparation et leurs applications.
PT1562604E (pt) * 2002-10-23 2012-04-09 Sucampo Ag Compostos de prostaglandina para o tratamento de obesidade
CN1753680B (zh) * 2002-12-27 2010-12-08 苏坎波公司 用于治疗腹部不适的前列腺素衍生物
JP5294559B2 (ja) * 2003-07-03 2013-09-18 スキャンポ・アーゲー クロライドチャンネルオープナーとしてプロスタグランジンアナログを含む腸溶性組成物
TWI495471B (zh) * 2003-08-12 2015-08-11 R Tech Ueno Ltd 促進毛髮生長之組成物及方法
TWI387454B (zh) 2004-09-02 2013-03-01 Sucampo Ag 治療胃腸道疾病之方法及組成物
ES2371658T3 (es) * 2005-04-12 2012-01-05 Sucampo Ag Uso combinado de compuesto de prostaglandina e inhibidor de la bomba de protones para el tratamiento de trastornos gastrointestinales.
CN101466407B (zh) 2006-01-24 2013-05-15 株式会社·R-技术上野 包含双环化合物的药物组合物和使所述双环化合物稳定的方法
WO2007086536A2 (en) * 2006-01-24 2007-08-02 R-Tech Ueno, Ltd. Soft-gelatin capsule formulation
WO2007091697A2 (en) * 2006-02-07 2007-08-16 R-Tech Ueno, Ltd. Method for preparing prostaglandin derivative
US20090030072A1 (en) 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
US20090012165A1 (en) 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
KR101485212B1 (ko) * 2007-07-19 2015-01-22 가부시키가이샤 아루떼꾸 우에노 11-데옥시-프로스타글란딘 화합물을 포함하는 약학 조성물 및 상기 화합물을 안정화시키는 방법
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
CN101318948B (zh) * 2008-04-01 2011-04-27 上海天伟生物制药有限公司 鲁比前列酮晶体、其制备方法及用途
US8569279B2 (en) * 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
CN102498105B (zh) 2009-07-28 2014-04-02 小野药品工业株式会社 双环化合物及其医疗用途
BR112012006069A8 (pt) * 2009-09-18 2017-10-10 Adolor Corp Método para tratar ou prevenir constipação induzida e disfunção intestinal induzida por opióide em um humano, e, uso de uma quantidade terapeuticamente efetiva de composto
WO2011054087A1 (en) * 2009-11-03 2011-05-12 Bernard Charles Sherman Stable pharmaceutical formulations comprising lubiprostone
EP2669279B1 (en) 2011-01-27 2017-01-11 ONO Pharmaceutical Co., Ltd. Bicyclic compound and use thereof for medical purposes
WO2012102355A1 (ja) * 2011-01-27 2012-08-02 小野薬品工業株式会社 二環式化合物およびその医薬用途
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
EP3277274B1 (en) 2015-04-01 2024-06-12 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
ES2890989T3 (es) 2016-06-30 2022-01-25 Ono Pharmaceutical Co Método para producir un compuesto bicíclico
WO2018065826A1 (en) 2016-10-06 2018-04-12 Sucampo Ag Multilayer beads for pharmaceutical use
JPWO2019221215A1 (ja) * 2018-05-18 2021-05-27 ニプロ株式会社 ルビプロストン含有粒子状医薬組成物
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Also Published As

Publication number Publication date
US7417067B2 (en) 2008-08-26
RU2695274C9 (ru) 2020-01-22
DK1426361T4 (en) 2015-03-16
US8088934B2 (en) 2012-01-03
AU2004242503B2 (en) 2007-06-21
AR109354A2 (es) 2018-11-21
KR100830061B1 (ko) 2008-05-16
HUP0203746A3 (en) 2005-02-28
EP1426361A1 (en) 2004-06-09
RU2695274C2 (ru) 2019-07-22
US20040235885A1 (en) 2004-11-25
RU2002112984A (ru) 2004-01-20
CN1379769A (zh) 2002-11-13
US8097649B1 (en) 2012-01-17
ES2309410T3 (es) 2008-12-16
HU230484B1 (hu) 2016-07-28
HK1045693A1 (en) 2002-12-06
CA2385732A1 (en) 2001-04-19
CZ20021037A3 (cs) 2002-09-11
AR089848A2 (es) 2014-09-24
HK1066792A1 (en) 2005-04-01
TR200201032T2 (tr) 2002-08-21
BRPI0014869B8 (pt) 2021-05-25
PT1426361E (pt) 2008-10-08
JP2003511445A (ja) 2003-03-25
ES2309410T5 (es) 2015-03-17
US20080255227A1 (en) 2008-10-16
CZ303625B6 (cs) 2013-01-16
WO2001027099A3 (en) 2001-10-25
HUP1300369A2 (zh) 2003-03-28
EP1220849B1 (en) 2004-05-19
EP1426361B2 (en) 2015-02-25
EP1220849A2 (en) 2002-07-10
DK1426361T3 (da) 2008-11-17
AU780342B2 (en) 2005-03-17
NO20021736L (no) 2002-04-12
PT1220849E (pt) 2004-10-29
TWI281918B (en) 2007-06-01
AU2004242503A1 (en) 2005-01-27
BRPI0014869B1 (pt) 2017-06-13
EP1426361B1 (en) 2008-07-30
JP4332316B2 (ja) 2009-09-16
AU2004242503C1 (en) 2005-01-27
HK1045693B (zh) 2005-01-21
NZ518020A (en) 2004-02-27
DE60010913T2 (de) 2005-06-09
CA2385732C (en) 2009-02-10
DK1220849T3 (da) 2004-09-27
JP2009235079A (ja) 2009-10-15
ZA200202312B (en) 2002-12-24
AU7685600A (en) 2001-04-23
ATE267189T1 (de) 2004-06-15
ES2221859T3 (es) 2005-01-16
US20120095090A1 (en) 2012-04-19
NO20021736D0 (no) 2002-04-12
MXPA02003756A (es) 2005-09-08
AR026046A1 (es) 2002-12-26
HUP0203746A2 (hu) 2003-03-28
HU229547B1 (en) 2014-01-28
NO330258B1 (no) 2011-03-14
CN1268623C (zh) 2006-08-09
BR0014869A (pt) 2002-06-25
US6583174B1 (en) 2003-06-24
DE60010913D1 (de) 2004-06-24
KR20020068521A (ko) 2002-08-27
ATE402925T2 (de) 2008-08-15
RU2695274C3 (ru) 2020-11-09
IL148803A (en) 2006-07-05
WO2001027099A2 (en) 2001-04-19
DE60039727D1 (de) 2008-09-11

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