IL144697A0 - Microbial process for preparing paravastatin - Google Patents

Microbial process for preparing paravastatin

Info

Publication number
IL144697A0
IL144697A0 IL14469700A IL14469700A IL144697A0 IL 144697 A0 IL144697 A0 IL 144697A0 IL 14469700 A IL14469700 A IL 14469700A IL 14469700 A IL14469700 A IL 14469700A IL 144697 A0 IL144697 A0 IL 144697A0
Authority
IL
Israel
Prior art keywords
paravastatin
preparing
microbial process
microbial
preparing paravastatin
Prior art date
Application number
IL14469700A
Other languages
English (en)
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of IL144697A0 publication Critical patent/IL144697A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL14469700A 1999-02-03 2000-02-03 Microbial process for preparing paravastatin IL144697A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11845899P 1999-02-03 1999-02-03
US13475999P 1999-05-18 1999-05-18
PCT/US2000/002993 WO2000046175A1 (en) 1999-02-03 2000-02-03 Microbial process for preparing pravastatin

Publications (1)

Publication Number Publication Date
IL144697A0 true IL144697A0 (en) 2002-06-30

Family

ID=26816384

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14469700A IL144697A0 (en) 1999-02-03 2000-02-03 Microbial process for preparing paravastatin

Country Status (27)

Country Link
EP (1) EP1154979B1 (enExample)
JP (2) JP3645491B2 (enExample)
KR (2) KR20060061406A (enExample)
CN (3) CN1177793C (enExample)
AR (2) AR023368A1 (enExample)
AT (1) ATE294771T1 (enExample)
AU (2) AU774438B2 (enExample)
BG (1) BG105778A (enExample)
BR (1) BR0009180A (enExample)
CA (1) CA2361701C (enExample)
CZ (1) CZ20012761A3 (enExample)
DE (1) DE60019898T2 (enExample)
ES (1) ES2240072T3 (enExample)
HK (1) HK1042686B (enExample)
HR (1) HRP20010577B1 (enExample)
HU (1) HUP0200650A3 (enExample)
IL (1) IL144697A0 (enExample)
IS (1) IS6036A (enExample)
MX (1) MXPA01007807A (enExample)
NO (1) NO20013818L (enExample)
PL (1) PL350317A1 (enExample)
PT (1) PT1154979E (enExample)
RU (1) RU2004127981A (enExample)
SK (1) SK10932001A3 (enExample)
TR (2) TR200600009T2 (enExample)
WO (1) WO2000046175A1 (enExample)
YU (1) YU55701A (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI20305A (sl) † 1999-08-06 2001-02-28 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristali natrijeve soli pravastatina
EP1798214A3 (en) * 1999-11-30 2007-08-01 Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság Process for recovering statin compounds from a fermentation broth
AU1804601A (en) * 1999-11-30 2001-06-12 Biogal Gyogyszergyar Rt Process for recovering statin compounds from a fermentation broth
KR20020062340A (ko) 1999-12-14 2002-07-25 비오갈 기오기스제르갸르 알티. 신규 형태의 프라바스타틴 나트륨
HRP20030347A2 (en) * 2000-10-05 2005-04-30 Teva Gy�gyszergy�r R�szv�nyt�rsas�g Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
JP2003026634A (ja) * 2001-07-17 2003-01-29 Mercian Corp プラバスタチンナトリウム塩の製造方法
JP3463875B2 (ja) 2001-08-06 2003-11-05 三共株式会社 プラバスタチンを精製する方法
JP3422791B2 (ja) 2002-08-06 2003-06-30 三共株式会社 プラバスタチンの単離・精製方法
KR100540761B1 (ko) * 2002-08-09 2006-01-16 코바이오텍 (주) 프라바스타틴 나트륨의 제조방법
EP1452519A1 (en) * 2003-02-25 2004-09-01 Balkanpharma-Razgrad AD Method for the isolation and purification of pravastatin sodium
WO2004096785A1 (ja) * 2003-04-25 2004-11-11 Nippon Chemiphar Co., Ltd. （２s，３s）－３－［［（１s）－１－イソブトキシメチル－３－メチルブチル］カルバモイル］オキシラン－２－カルボン酸の塩
CN1244688C (zh) 2003-07-09 2006-03-08 上海天伟生物制药有限公司 生产普伐他汀钠的微生物和方法
TWI319707B (en) 2003-11-24 2010-01-21 Method of purifying pravastatin
TWI307360B (en) 2004-12-03 2009-03-11 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for constructing strain having compactin hydroxylation ability
US20110130450A1 (en) * 2008-04-02 2011-06-02 Aad Johannes Bouman Pravastatin extraction
EP3714959A1 (en) * 2019-03-29 2020-09-30 Basf Se Isolation of small molecules from the fermentation broth of a eukaryotic microorganism
CN117164541B (zh) * 2022-05-27 2025-09-30 黑龙江华瑞生物科技有限公司 一种从美伐他汀母液中分离纯化美伐他汀的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE249514T1 (de) * 1996-03-28 2003-09-15 Dsm Ip Assets Bv Verfahren zur herstellung von granulärer mikrobieller biomasse und gewinnung wertvoller komponenten aus mikrobieller biomasse

Also Published As

Publication number Publication date
EP1154979A4 (en) 2004-05-26
HK1042686A1 (en) 2002-08-23
CN1590363A (zh) 2005-03-09
CN1177793C (zh) 2004-12-01
SK10932001A3 (sk) 2002-06-04
KR20060061406A (ko) 2006-06-07
HRP20010577B1 (en) 2005-12-31
AU774438B2 (en) 2004-06-24
DE60019898T2 (de) 2006-08-10
HRP20010577A2 (en) 2002-12-31
AU3356700A (en) 2000-08-25
RU2004127981A (ru) 2006-03-10
CN1260344C (zh) 2006-06-21
ES2240072T3 (es) 2005-10-16
CN1347400A (zh) 2002-05-01
CA2361701C (en) 2007-04-10
JP4197312B2 (ja) 2008-12-17
JP3645491B2 (ja) 2005-05-11
IS6036A (is) 2001-08-02
PL350317A1 (en) 2002-12-02
KR100648541B1 (ko) 2006-11-24
CZ20012761A3 (cs) 2002-05-15
TR200600009T2 (tr) 2006-08-21
EP1154979A1 (en) 2001-11-21
NO20013818D0 (no) 2001-08-03
CA2361701A1 (en) 2000-08-10
PT1154979E (pt) 2005-08-31
JP2002535977A (ja) 2002-10-29
HUP0200650A2 (en) 2002-08-28
ATE294771T1 (de) 2005-05-15
AR023368A1 (es) 2002-09-04
EP1154979B1 (en) 2005-05-04
BG105778A (bg) 2002-05-31
AU2004214559A1 (en) 2004-10-21
CN1537935A (zh) 2004-10-20
NO20013818L (no) 2001-10-03
DE60019898D1 (de) 2005-06-09
WO2000046175A1 (en) 2000-08-10
JP2005047924A (ja) 2005-02-24
KR20010112257A (ko) 2001-12-20
HK1042686B (en) 2005-10-14
YU55701A (sh) 2004-07-15
MXPA01007807A (es) 2003-06-04
TR200103127T2 (tr) 2002-04-22
BR0009180A (pt) 2002-03-26
AR061765A2 (es) 2008-09-17
HUP0200650A3 (en) 2008-03-28

Similar Documents

Publication Publication Date Title
HUP0203206A3 (en) Process for preparing 4-trifluoromethylsulphinylpyrazole derivative
GB9928977D0 (en) Process
GB9928132D0 (en) Process
GB9917851D0 (en) Process
IL147588A0 (en) Microbial process for preparing pravastatin
IL144697A0 (en) Microbial process for preparing paravastatin
GB9926854D0 (en) Process
GB9924285D0 (en) Process
GB9914209D0 (en) Process
GB9905512D0 (en) Process
GB9926855D0 (en) Process
GB9908814D0 (en) Process
SG83788A1 (en) Method for preparing polymer
IL145791A0 (en) Process for preparing mkc-442
GB9904162D0 (en) Process
HUP0103002A3 (en) New process for obtaining 17betha-(n-terc-butylcarbamoyl)-3-one-4-aza-steroids
HUP0000559A3 (en) Process for preparing cyanoaceticacidesters
GB9930599D0 (en) Process
GB9917291D0 (en) Process for preparing polymers
GB9905418D0 (en) Process
GB9908662D0 (en) Novel process for preparing benzodiazepines
GB9903087D0 (en) Process
GB9917330D0 (en) Process
SI1154979T1 (en) Microbial process for preparing pravastatin
AU1725400A (en) Process for preparing acylaromatic compounds

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees