IL132304A0 - Osteoprotegerin binding proteins and receptors - Google Patents
Osteoprotegerin binding proteins and receptorsInfo
- Publication number
- IL132304A0 IL132304A0 IL13230498A IL13230498A IL132304A0 IL 132304 A0 IL132304 A0 IL 132304A0 IL 13230498 A IL13230498 A IL 13230498A IL 13230498 A IL13230498 A IL 13230498A IL 132304 A0 IL132304 A0 IL 132304A0
- Authority
- IL
- Israel
- Prior art keywords
- fragments
- encoding
- sequence
- nucleic acid
- receptors
- Prior art date
Links
- 102000014914 Carrier Proteins Human genes 0.000 title abstract 2
- 108091008324 binding proteins Proteins 0.000 title abstract 2
- 102000008108 Osteoprotegerin Human genes 0.000 title 1
- 108010035042 Osteoprotegerin Proteins 0.000 title 1
- XXUPLYBCNPLTIW-UHFFFAOYSA-N octadec-7-ynoic acid Chemical compound CCCCCCCCCCC#CCCCCCC(O)=O XXUPLYBCNPLTIW-UHFFFAOYSA-N 0.000 title 1
- 102000005962 receptors Human genes 0.000 title 1
- 108020003175 receptors Proteins 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 208000020084 Bone disease Diseases 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 210000002997 osteoclast Anatomy 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/842,842 US5843678A (en) | 1997-04-16 | 1997-04-16 | Osteoprotegerin binding proteins |
| US88085597A | 1997-06-23 | 1997-06-23 | |
| US09/052,521 US6316408B1 (en) | 1997-04-16 | 1998-03-30 | Methods of use for osetoprotegerin binding protein receptors |
| PCT/US1998/007584 WO1998046751A1 (en) | 1997-04-16 | 1998-04-15 | Osteoprotegerin binding proteins and receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL132304A0 true IL132304A0 (en) | 2001-03-19 |
Family
ID=27368158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13230498A IL132304A0 (en) | 1997-04-16 | 1998-04-15 | Osteoprotegerin binding proteins and receptors |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7923008B2 (cs) |
| EP (2) | EP1717315A3 (cs) |
| JP (2) | JP2001526532A (cs) |
| CN (1) | CN1264427A (cs) |
| AT (1) | ATE363533T1 (cs) |
| AU (4) | AU743257B2 (cs) |
| BG (1) | BG65242B1 (cs) |
| BR (1) | BR9808545A (cs) |
| CA (1) | CA2285746C (cs) |
| CZ (1) | CZ302262B6 (cs) |
| DE (1) | DE69837845T3 (cs) |
| DK (1) | DK0975754T4 (cs) |
| EA (1) | EA003636B1 (cs) |
| EE (1) | EE05496B1 (cs) |
| ES (1) | ES2284203T5 (cs) |
| HU (1) | HU230547B1 (cs) |
| ID (1) | ID23855A (cs) |
| IL (1) | IL132304A0 (cs) |
| NO (1) | NO325175B1 (cs) |
| NZ (1) | NZ500253A (cs) |
| PL (1) | PL190092B1 (cs) |
| RO (1) | RO128635A2 (cs) |
| SI (1) | SI0975754T2 (cs) |
| SK (1) | SK288559B6 (cs) |
| TR (1) | TR199902512T2 (cs) |
| TW (1) | TW589376B (cs) |
| WO (1) | WO1998046751A1 (cs) |
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| IL117175A (en) | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
| EP1114864B9 (en) | 1996-12-13 | 2013-05-08 | Schering Corporation | Mammalian cell surface antigens, related reagents |
| DE122010000048I1 (de) * | 1996-12-23 | 2011-05-05 | Immunex Corp | Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie |
| US6271349B1 (en) | 1996-12-23 | 2001-08-07 | Immunex Corporation | Receptor activator of NF-κB |
| DE122010000049I1 (de) | 1997-04-15 | 2011-05-05 | Daiichi Sankyo Co Ltd | Neues protein und verfahren zu dessen herstellung |
| AU2008200700C1 (en) * | 1997-04-15 | 2013-04-04 | Daiichi Sankyo Co., Ltd | Novel Protein and Process for Producing The Same |
| ATE363533T1 (de) | 1997-04-16 | 2007-06-15 | Amgen Inc | Osteoprotegerin bindende proteine und rezeptoren |
| US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| EP1076699B1 (en) * | 1998-05-14 | 2008-10-29 | Immunex Corporation | Method of inhibiting osteoclast activity |
| US20020106728A1 (en) * | 2000-06-20 | 2002-08-08 | Genentech, Inc. | NS4 nucleic acids and polypeptides and methods of use for the treatment of body weight disorders |
| SI1114166T1 (en) * | 1998-09-15 | 2005-10-31 | Pharmexa A/S | Method for down-regulating osteoprotegerin ligand activity |
| ES2239457T3 (es) | 1998-09-15 | 2005-09-16 | Pharmexa A/S | Procedimiento para regular a niveles mas bajos la actividad de ligando de osteoprotegerina. |
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| WO2001023559A1 (en) * | 1999-09-27 | 2001-04-05 | Eli Lilly And Company | Osteoclast differentiation factor regulatory region |
| AUPQ314799A0 (en) * | 1999-09-29 | 1999-10-21 | University Of Western Australia, The | Bone cell factor |
| ATE511857T1 (de) | 2000-02-16 | 2011-06-15 | Genentech Inc | Anti-april monoklonaler antikörper und deren verwendung zur behandlung von immunerkrankungen oder krebs |
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| JP4401613B2 (ja) * | 2000-02-23 | 2010-01-20 | アムジエン・インコーポレーテツド | オステオプロテゲリン結合タンパク質のアンタゴニスト性選択的結合因子 |
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1998
- 1998-04-15 AT AT98918244T patent/ATE363533T1/de active
- 1998-04-15 CN CN98806073A patent/CN1264427A/zh active Pending
- 1998-04-15 IL IL13230498A patent/IL132304A0/xx unknown
- 1998-04-15 EE EEP199900611A patent/EE05496B1/xx unknown
- 1998-04-15 ES ES98918244.9T patent/ES2284203T5/es not_active Expired - Lifetime
- 1998-04-15 EP EP06015956A patent/EP1717315A3/en not_active Withdrawn
- 1998-04-15 SK SK1419-99A patent/SK288559B6/sk active Protection Beyond IP Right Term
- 1998-04-15 AU AU71205/98A patent/AU743257B2/en not_active Ceased
- 1998-04-15 HU HU0001400A patent/HU230547B1/hu unknown
- 1998-04-15 DK DK98918244.9T patent/DK0975754T4/en active
- 1998-04-15 PL PL98336311A patent/PL190092B1/pl unknown
- 1998-04-15 ID IDW991225A patent/ID23855A/id unknown
- 1998-04-15 EP EP98918244.9A patent/EP0975754B2/en not_active Expired - Lifetime
- 1998-04-15 JP JP54425798A patent/JP2001526532A/ja not_active Withdrawn
- 1998-04-15 RO ROA201200577A patent/RO128635A2/ro unknown
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- 1998-04-15 EA EA199900939A patent/EA003636B1/ru not_active IP Right Cessation
- 1998-04-15 BR BR9808545-0A patent/BR9808545A/pt not_active Application Discontinuation
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- 1998-04-15 WO PCT/US1998/007584 patent/WO1998046751A1/en not_active Ceased
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